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Curriculum Vitae

Prof. Armando Gabrielli

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ARMANDO GABRIELLI

Istituto di Clinica Medica Generale, Ematologia ed Immunologia Clinica

Università Politecnica delle Marche

Polo Didattico

Via Tronto,10

60020 Ancona

Tel 071 2206104

Fax 071 2206103

E-mail a.gabrielli@univpm.it

CURRICULUM ATTIVITA' SCIENTIFICA E DIDATTICA

Nato a Riccione (FO) il 27/1/1950. Residente ad Ancona

Posizione attuale

Professore Ordinario. Insegnamento di Medicina Interna nel Corso di Laurea in Medicina e Chirurgia, Facoltà di Medicina e Chirurgia, Università Politecnica delle Marche Professore Ordinario. Insegnamento di Immunologia Clinica nel Corso di Laurea in Medicina e Chirurgia, Facoltà di Medicina e Chirurgia, Università Politecnica delle Marche

Direttore della Clinica Medica Facoltà di Medicina e Chirurgia, Università Politecnica delle Marche Direttore del Servizio di immunologia, Ospedali Riuniti, Ancona

Appartenenza a Società Scientifiche e Gruppi di ricerca

-Società Italiana di Immunologia, Immunologia clinica ed Allergologia; -Società Italiana di Reumatologia; -Società Italiana di Medicina Interna; -Membro del Comitato Scientifico dell’ AILS (Associazione Italiana per la Lotta alla Sclerodermia) - Membro del Comitato Tecnico Scientifico dell’ International workshop on Scleroderma Research - Membro del Comitato Tecnico Scientifico dell’ European Scleroderma Trials and Research group

(EUSTAR)

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Incarichi Istituzionali

- Direttore della Scuola di Specializzazione in Medicina Interna della Facolta’ di Medicina e Chirurgia dell’ Università Politecnica delle Marche; - Direttore della Scuola di Specializzazione in Medicina d’Urgenza della Facolta’ di Medicina e Chirurgia dell’ Università Politecnica delle Marche; - Direttore della Scuola di Specializzazione in Allergologia ed Immunologia Clinica della Facolta’ di Medicina e Chirurgia dell’ Università Politecnica delle Marche; - Presidente della Fondazione “Medicina Molecolare e Terapia Cellulare” dell’ Università Politecnica delle Marche; - Direttore del Dipartimento di Medicina Interna e Specialistica degli Ospedali Riuniti di Ancona. - Direttore del Corso di Dottorato “Salute dell’Uomo” della Facolta’ di Medicina e Chirurgia dell’ Università Politecnica delle Marche; - Direttore della Clinica Medica della Facolta’ di Medicina e Chirurgia dell’ Università Politecnica delle Marche; - Direttore del Servizio di Immunologia Clinica degli Ospedali Riuniti di Ancona.

Stages

Externship presso il Medical Service Cook County Hospital di Chicago, U.S.A., (1973); Stage presso l'Istituto di Genetica Medica dell'Università di Torino(1975); Visiting Professor presso il Department of Laboratory Medicine, University of South Carolina, Charleston, U.S.A. (1982). Stage presso il Max Planck Institut fur Biochemie, Martinsried (Germania) (1985 e 1988)

Borse di studio

Borsa di Studio della European Molecular Biology Organization (EMBO) (1985)

Attività Editoriale

Funzioni di Referee per le riviste: -Clinical Experimental Rheumatology -Journal of Investigative Dermatology -Arthritis & Rheumatology -J Rheumatol

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-Free Radical Biology and Medicine -Eur J Epid - NEJM

PUBBLICAZIONI

1. Curtoni E.S., Gabrielli A. Platelet transfusion. Haematologica 61, 498- 510,1976

2. Milani-Comparetti M., Diotallevi P., Cervini C., Grassi W., Gabrielli A. HLA and psoriasis (with and without arthropathy). Boll. Soc It. Biol. Sper. 58, 148-154,1982.

3. Gabrielli A, De Nictolis M., Campanati G., Cinti S. Eosinophilic fasciitis: a mast cell

disorder? Clin. Exp. Rheumatol. 1,75-80,1983.

4. Gabrielli A., Saper R., DeLustro F. Human IgG binds to laminin of basement membrane.

Folia Allerg. Immunol. Clin. 4, 112,1983.

5. La Via M.F., Misefari A., Venza-Teti D., Teti G., Gabrielli A. Pavese I. Depression of direct plaque-forming cell response in mouse spleen cell cultures by aggregated IgG2b-induced factors. Immunology Letters 8,165-168,1984.

6. Corvetta A., Spaeth P.J., Gabrielli A., Ghirelli P.A., Orecchioni F., Montroni M., Danieli G. Capacity to solubilize immune precipitates or to prevent their formation expressed by sera and synovial fluids from patients affected by immune complex diseases. EOS 4,173-177,1984.

7. Gabrielli A., Corvetta A., Montroni M., Rupoli S., Danieli G. Immune deposits in normal skin of patients with systemic lupus erythematosus: relationship to the serum capacity to solubilize immune complexes. Clin Immunol. Immunopathol. 36, 266- 274,1985.

8. Gabrielli A., Montroni M., Rupoli S., Caniglia M.L., DeLustro F., Danieli G. Antibodies to type IV collagen in patients with scleroderma and idiopathic Raynaud's phenomenon. It. J. Med. 1, 26- 27,1985.

9. Danieli G., Marchegiani G., Gabrielli A. Essential cryoglobulinemia: a therapeutic dilemma. La Ric. Clin. Lab. 16, 393- 401, 1986.

10. Gabrielli A., Sbarbati A., Marchegiani G., Rupoli S., Montroni M., Cinti S., Danieli G. Abnormalities of vessel walls of normal skin of patients with essential mixed cryoglobulinemia. An ultrastructural study. La Ric. Clin. Lab. 16, 335- 340,1986.

11. Bianchini R., Gabrielli A. Necrolytic migratory erythema, due to zinc deficiency?. It. Gen. Review Dermatol. 23, 21-26, 1986.

12. Gabrielli A., Sbarbati A., Marchegiani G., Rupoli S., Montroni M., Cinti S., Danieli G. Evidence of immune deposits and of basement membrane alterations in dermal vessels of normal skin of patients with essential mixed cryoglobulinemia. Arthritis Rheum. 30, 884- 893,1987.

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13. Peruccio D., Crepaldi D., Lovisone E., Paolino F., Foa R., Castagnoli G., Gabrielli A.,

Cappa P.M.A., Richiardi P. HLA class I-like expression on human leukemic cells. Tissue Antigens 30, 76-83, 1987.

14. Gabrielli A., Marchegiani G., Rupoli S., Ansuini G., Brocks D.G., Danieli G., Timpl R. Assessment of disease activity in essential cryoglobulinemia by serum levels of a basement membrane antigen, laminin. Arthritis Rheum. 31, 1558- 1562, 1988.

15. Gerstmeier H, Gabrielli A., Meurer M., Brocks D., Braun-Falco O., Krieg T. Levels of type IV collagen and laminin fragments in serum from patients with progressive systemic sclerosis. J. Rheumatol. 15, 969- 972,1988.

16. Gabrielli A., Montroni M., Rupoli S., Caniglia M.L., DeLustro F., Danieli G. A kretrospective study of antibodies against basement membrane antigens, type IV collagen and laminin, in patients with primary and secondary Raynaud's phenomenon. Arthritis Rheum. 31, 1432-1436, 1988.

17. Gabrielli A., Silver R., Teti G., Chiofalo M.S., Misefari A., Venza-Teti D., Virella G., La Via

M.F. Depression by Fc gamma receptor ligands of SRBC- induced IgM-PFC generation in human blood mononuclear cell cultures. Diag. Clin. Immunol. 5,304-308,1988.

18. Gabrielli A., Silver R., Teti G., Chiofalo M.S., Misefari A., Venza-Teti D., Virella G., La Via

M.F. Mononuclear cells from Rheumatoid Arthritis patients exhibit a depressed IgM response to sheep erythrocyte stimulation in vitro. Diag. Clin. Immunol. 5, 266-268, 1988.

19. Frongia G.B., Brianzoni M.F., Pirani A., Candela M., Gabrielli A. Primary and secondary sicca syndrome: clinical and immunological features. New Trends In Ophtal. 3, 263-269,1988.

20. Gabrielli A., Corvetta A., Montroni M., Marchegiani G., Danieli G. Essential cryoglobulinemia: clinical and laboratory aspects of 56 patients. It. J. Med. 4, 137- 143,1988.

21. Offidani A.M., Simonetti O., Politi A., Salvi A., Gabrielli A., Bossi G. Antigeni HLA e alopecia areata. G. It. Dermatol. Vener. 123, 409-412,1988.

22. Litargini P., Centurioni R., Gabrielli A., Brianzoni , Reginelli R., Rupoli S., Candela M.,

Leoni P. Viscosità plasmatica e sierica in alcune emopatie: dati preliminari Hematologica 4, 223-225,1988.

23. Corvetta A., Della Bitta R., Gabrielli A., Spaeth P.J., Danieli G. Use of high dose intravenous immunoglobulin in systemic lupus erythematosus: report of three cases. Clin. Exp. Rheumatol. 7, 295-299,1989.

24. Wieslander J., Mansson O., Kallin E., Gabrielli A., Nowack H., Timpl R. Specificity of human antibodies against Gal a1-3 Gal carbohydrate epitope and distinction from natural antibodies with Gal a1-2 Gal or Gal a1-4 Gal. Glycoconjugate J. 7,85-100,1990.

25. Montesi A., Pesaresi A., Cavalli M.L., Serri L., Salmistrazo D., Candela M., Gabrielli A. Correlazione tra studio radiologico della deglutizione e quadro clinico nella sclerosi sistemica

(sclerodermia). Radiol Med 80, 296-300, 1990

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26. Montesi A., Pesaresi A., Cavalli M.L., Ripa G., Candela M., Gabrielli A. Oralpharingeal

and esophageal function in scleroderma. Dysphagia 6: 219- 223, 1991

27. Gabrielli A., Leoni P., Danieli G., Hermann K., Krieg T., Wieslander J. Antibodies against

galactosyl- (a1-3) galactose in connective tissue diseases. Arthritis & Rheum 34, 375-6, 1991

28. Gabrielli A., Candela M., Ricciatti A.M., Caniglia M.L., Wieslander J. Antibodies to mouse laminin in patients with systemic sclerosis (scleroderma) recognize galactosyl (a1-3)

galactose epitopes. Clin Exp Immunol 86:367-373,1991

29. Galli M. Gabrielli A, and the Italian Group for the study of cryoglobulinemias (IGSC)

Cryoglobulinaemia and serological markers of hepatitis viruses Lancet 2, 758-759, 1991

30. Gabrielli A., Corvetta A., Montroni M., Ricciatti A.M., Nitti C., Danieli M.G., Danieli G. Clinical features and outcome of 80 patients with Systemic Lupus Erythematosus. J Immunol Res 3: 175-179, 1991

31. Gabrielli A, Danieli MG, Candela M, Ricciatti AM, Nitti C, Danieli G: The potential role of cytokines in the pathogenesis of systemic sclerosis (scleroderma). Int J Immunopathol Pharmacol 5, 135-140,1992

32. Danieli M.G., Markovitz D., Gabrielli A., Corvetta A., Giorgi P.L., van der Zee R., van

Embden J.D.A., Danieli G., Cohen I.R. Juvenile rheumatoid arthritis patients manifest immune reactivity to the mycobacterial 65 KD heat shock protein, to its 180- 188 peptide and to a partially homologous peptide of the proteoglycan link protein. Clin Immunol Immunopathol 64, 121-128,1992

33. Gabrielli A., Candela M., Pisani E., Hermann K., Wieslander J., Danieli G., Krieg T. Antibodies against terminal galactosyl (a1-3) galactose epitopes in systemic sclerosis (scleroderma). Clin Exp Rheumatol 10: 31-36, 1992

34. Danieli M.G., Candela M., Ricciatti A.M., Reginelli R., Caniglia M.L., Danieli G., Cohen I.,

Gabrielli A. Antibodies to mycobacterial heat shock protein in systemic sclerosis

(Scleroderma). J Autoimmunity 5: 443-452,1992

35. Monti G., Galli M., Gabrielli A. et al: Cryoglobulinemias: a multi-centre study of the early clinical and laboratory manifestation of primary and secondary disease. Q J Med 88: 115-126, 1995

36. Gabrielli A., Candela M., Cherubini G., Nitti C., Danieli G. Morphological and serological characterization of cryoglobulinemic vasculitis Conn Tiss Dis 11, 31-40, 1992

37. Candela M., Reginelli R., Ripa G., Salvi A., Gabrielli A., Danieli G.: Ketanserina e fenomeno di Raynaud primario esecondario. Efficacia terapeutica della somministrazione endovenosa associata a blocco loco-regionale. Minerva Angiol 17: 147-152, 1992.

38. Gabrielli A., Di Loreto C., Taborro R., Candela M, Sambo P, Nitti C, Danieli M.G.,

DeLustro F, Dasch J.R., Danieli G. Immunohistochemical localization of intracellular and

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extracellular associated TGFß in the skin of patients with systemic sclerosis (scleroderma) and primary Raynaud' phenomenon. Clin Immunol Immunopathol 68, 340-349, 1993

39. Leoni P., Rupoli S., Cinciripini A., Salvi A., Sambo P., Gabrielli A: Antibodies against terminal galactosyl (a1-3) galactose epitopes in patients with idiopathic myelofibrosis. Br J Haematol 85: 313-319,1993

40. Danieli M.G., Gabrielli A., Recchioni A., Danieli G.: Serum levels of soluble interleukin-2 receptors in patients with systemic lupus erythematosus and with systemic idiopathic

vasculitis. Scan J Rheumatol 22: 215 -219, 1993

41. Galli M., Monti F., Invernizzi F., Monteverde A., Bomardieri S., Gabrielli A., Migliaresi C.,

Mussini C., Ossi E., Pietrogrande M., Quintiliani L., Renoldi P., Vacca A., Saccardo F.,

Ferri C., Bordin G., Mazzaro C., Rusconi S., and the Italian Group for the Study of

Cryoglobulinemias (GISC): Hepatitis B virus-related markers in secondary and in essential mixed cryoglobulinemias: a multicentric study of 596 cases Ann Ital Med Int 7, 209-214, 1992

42. Manzin A., Candela M., Paolucci S., Caniglia ML, Gabrielli A., Clementi M.: Presence of hepatitis C virus (HCV) genomic RNA and viral replicative intermediates in bone marrow and peripheral blood mononuclear cells from HCV-infected patients. Clin Diagn Lab Immunol 1, 160-163,1994

43. Gabrielli A., Manzin A., Candela M., Caniglia M.L., Paolucci S., Danieli M.G., Clementi

M.: Active hepatitis C virus infection in bone marrow and peripheral blood mononuclear cells from patients with mixed cryoglobulinemia. Clin Exp Immunol 97, 87-93,1994

44. Ravaglia F., Candela M., Cherubini G., Da Lio L., Gabrielli A., De Sio G. Profilo emocoagulativo nel fenomeno di Raynaud primario e secondario Trombosi & Aterosclerosi 4, 337-344, 1993

45. Gabrielli A, Marrozzini C, Candela M, Ferretti RM, Recchioni A, Binetti GF, Danieli G: Prognostic significance of basement membrane antigens and soluble IL-2 receptor serum

concentrations in heart transplant rejection: Cardiologia 39, 481-486, 1994

46. Candela M, Ravaglia F, Cherubini G, da Lio L, Testa I, Gabrielli A: Primary Raynaud's phenomenon and systemic sclerosis: enothelial and platelet interaction in the development of hemocoagulative alterations. Eur J Lab Med 2, 185-189, 1994

47. Candela M., Cherubini G., Chelli F., Danieli G., Gabrielli A.: Fish-oil fatty acid

supplementation in mixed cryoglobulinemia: a preliminary report. Clin Exp Rheumatol 12, 509-513, 1994

48. Manzin A, Solforosi L, Bianchi D, Gabrielli A, Giostra F, Bruno S, Clementi M: Viral load from hepatitis C virus (HCV)-infected patients with various clinical conditions. Res Virol 146, 279-284, 1995

49. Gabrielli A, Sambo P, Zhu-Xu-Zhang, Candela M, Savoldi S, Manzin A, Clementi M,

Amoroso A, Sallberg M, Danieli G: Humoral immune response and natural killer activity in patients with mixed cryoglobulinemia. Clin Exp Rheumatol 13 (Suppl. 13): S95-S99,1995

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50. Casato M., Pucillo P.L., Leoni M., Di Lulo L, Gabrielli A., Sansonno D., Dammacco F.,

Danieli G., Bonomo L. Granulocypenia after combined therapy with interferon and angiotensin-converting enzyme inhibitors: evidence for a synergistic hematologic toxicity. Am J Med 99, 386-391,1995

51. Pioltelli P, Maldifassi P, and the GISC protocoll Group: GISC protocol experience in the

treatment of essential mixed cryoglobulinemia. Clin Exp Rheumatol 13 (Suppl. 13), S187-S190,1995

52. Piccinini G, Luchetti MM, Caniglia ML, Carossino AM, Montroni M, Introna M, Gabrielli

A: c-myb proto-oncogene is expressed by quiescent scleroderma fibroblasts and, unlike B-myb gene, does not correlate with proliferation. J Invest Dermatol 106, 1281-1286,1996

53. Gabrielli A, Cherubini G, Candela M, Savoldi S, Clementi M, Manzin A, Amoroso A,

Sallberg M: Differential humoral immune response against hepatitis C virus antigenic synthetic peptides in infected patients with and without mixed cryoglobulinemia. Clin Exp Immunol 105, 59-64, 1996

54. Manzin A, Solforosi L, Candela M, Cherubini G, Piccinini G, Gabrielli A, Clementi M: Hepatitis C virus infection and mixed cryoglobulinemia: assessment of HCV RNA copy numbers in supernatants, cryoprecipitates, and non-liver cells. J Vir Hepat 3, 285-292, 1996

55. Danieli G, Gabrielli A, Montroni M, Candela M, Pomponio G, Danieli MG, Fraticelli P,

Carratelli R. Neuro-LES. Modelli di espressione clinica. Rec Prog Med 87, 471- 475, 1996

56. Bagnarelli P, Candela M, Valenza A, Manzin A, Solforosi L, Mazzola F, Butini L,

Montroni M, Gabrielli A, Varaldo PE, Clementi M Dynamic features of human immunodeficiency virus type 1 (HIV-1) viremia: kinetics of cell-free HIV-1 RNA after therapeutic plasma exchange. J Infect Dis 176, 801-4, 1997

57. Gerli R, Muscat C, Giansanti M, Danieli MG, Sciuto M, Gabrielli A, Fiandra E, Vitali C: Quantitative assessment of salivary gland inflammatory infiltration in primary Sjogren's syndrome: its relationship to different demographic, clinical and serological features of the disorder Br J Rheumatol 36, 969-975, 1997

58. Manzin A, Solforosi L, Giostra F, Bianchi FB, Bruno S, Rossi S, Gabrielli A, Candela M,

Petrelli E, Clementi M: Quantitative analysis of hepatitis C virus activity in vivo in different groups of untreated patients. Arch Virol 142: 465-472 ,1997

59. Plaisant R, Burioni R, Manzin A, Solforosi L, Candela M, Gabrielli A, Fadda G, Clementi

M Human monoclonal recombinant Fabs specific for HCV antigens obtained by repertoire cloning in phage display combinatorial vectors Res Virol 148, 165-169, 1997

60. Candela M, Pansoni A, Tartari De Carolis S, Pomponio G, Corvetta A, Gabrielli A,

Danieli G: La capillaroscopia periungueale in pazienti con sindrome da immunità antifosfolipidica. Rec Prog Med 89, 444-449, 1998

61. Catassi C, Fabiani E, Coppa GV, Gabrielli A et al Elevata frequenza della infezione da virus dell'epatite C (HCV) nei pazienti con linfoma di Hodgkin all'esordio: risultati preliminari di uno studio multicentrico italiano. Rec Prog Med 89, 1-5, 1998

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62. Amoroso A, Berrino M, Canale L, Cornaglia M, Guarrera S, Mazzola G, Savoldi S,

Scolari F, Sallberg M, Clementi M, Gabrielli A: Are HLA class II and immunoglobulin constant region genes involved in the pathogenesis of mixed cryoglobulinemia type II after hepatitis C virus infection? J Hepatol 29, 36-44,1998

63. Danieli MG, Fraticelli P, Gabrielli A, Salvi A, Danieli G Undifferentiated connective tissue disease: natural history and evolution into definite CTD assessed in 84 patients initially

diagnosed as early UCTD Clin Rheumatol 17, 195-201, 1998

64. Burioni R, Plaisant P, Bugli F, Delli Carri V, Candela M, Gabrielli A Fadda G: Probing the natural antibody repertoire by combinatorial cloning of IgM and IgD isotypes in phage display vectors. Res Vir 149, 321-325, 1998

65. Sambo P, Jannino L, Donini M, Candela M, Salvi A, Dusi S, Gabrielli A. Monocytes of patients with systemic sclerosis (sceroderma) sponaneously release in vitro increased amounts of superoxide anion. J Invest Dermatol 112, 78-84, 1999

66. 101) Piccinini G, Golay J, Flora A, Songia S, Luchetti M, Gabrielli A, Introna M: c-myb, but not B-myb, upregulates type I collagen gene expression in human fibroblasts. J Invest Dermatol 112, 191-196, 1999

67. Scortechini AR, Rupoli S, Piccinini G, Luchetti MM, Cantori I, Gabrielli A, Leoni P. Expression of c-myb and B-myb oncogenes on myielofibrotic marrow fibroblasts. Leuk Lymphoma 33, 295-304, 1999

68. Manzin A, Candela M, Solforosi L, Gabrielli A, Clementi M. Dynamics of hepatitis C virus viremia after perturbation by plasma exchange. J Hepatol 31, 389-393,1999

69. Falcini F, Azzari C, Gelli A, Luchetti M, Gabrielli A, Calzolari A, Pignone A, Generini S,

Matucci Cerinic M. Reduction of bcl-2 in T cells during immunosuppressive therapy in patients with severe juvenile onset systemic lupus erythematosus. Clin Immunol 93, 59-64,1999

70. Luchetti M M, Piccinini G, Introna M, Peri G, Matteucci C, Pomponio G, Fratini M,

Fraticelli P, Sambo P, Mantovani A, Gabrielli A. Expression and production of the long pentraxin PTX3 in rheumatoid arthritis. Clin Exp Immunol 119, 196-202, 2000

71. Grigolo B, Mazzetti I, Meliconi R, Bazzi S, Scorza R, Candela M, Gabrielli A, Facchini A. Anti- Association with pulmonary hypertension and HLA-B35. Clin Exp Immunol 121, 539-43, 2000

72. Della Rossa A, Valentini G, Bombardieri G, Bencivelli W, Silman AJ, D’Angelo S, Matucci-Cerinic

M, Belch JF, Black CM, Becvar R, Bruhlman P, Cozzi F, Czrjak L, Drosos AA, Dziankowska B,

Ferri C, Gabrielli A, , Giacomelli R, Hayem G, Inanc M, McHugh NJ, Nielsen H, Scorza R, Tirri E, ,

Van den Hoogen FHJ, Vlachoyiannopoulos PG. European multicentre study to define disease activity criteria of Systemic Sclerosis. I. Clinical and epidemiological features of 290 patients from 19 centres. Ann Rheum Dis 60, 585-591,2001

73. Valentini G, Della Rossa A, Bombardieri G, Bencivelli W, Silman AJ, D’Angelo S, Matucci-Cerinic

M, , Belch JF, Black CM, Bruhlman P, Czrjak L, De Luca A, Drosos AA, Ferri C, Gabrielli A,

Giacomelli R, Hayem G, Inanc M, McHugh NJ, Nielsen H, Rosada M, Scorza R, Stork J, Sysa A,

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Van den Hoogen FHJ, Vlachoyiannopoulos PG. . European multicentre study to define disease activity criteria of Systemic Sclerosis II. Identification of disease activity variables and development of preliminary activity indexes. Ann Rheum Dis 60, 592-598,2001

74. Sambo P, Svegliati-Baroni S, Paroncini P, Luchetti M, Dusi S, Orlandini G, Gabrielli A. Oxidative stress in scleroderma: maintenance of scleroderma fibroblast phenotype by the constitutive upregulation of free radical generation through the NADPH oxidase complex pathway. Arthritis Rheum 44, 2653-2664, 2001

75. Sambo P, Amico D, Giacomelli R, Matucci-Cerinic M, Valentini G, Salsano F, Gabrielli A. Intravenous N-acetylcysteine for treatment of Raynaud’s phenomenon secondary to systemic sclerosis: a pilot study. J Rheumatol 28,2257-62, 2001

76. Bugli F, Mancini N, Kang C-Y, Di Campli C, Grieco A, Manzin A, Gabrielli A, Gasbarrini A, Fadda

G, Varaldo PE, Clementi M, Burioni R. Mapping B-cell epitopes of hepatitis C virus E2 glycoprotein using human monoclonal antibodies from phage display libraries. J Virol 75, 9986-9990, 2001

77. Gabrielli A, Sambo P. Scleroderma: amidst weak genes and vague environment, where is the culprit? Ann Ital Med Intern 16, 5-6, 2001

78. Candela M, Pansoni A, Jannino L, Menditto V, Natalini M, Ravaglia, F, Da Lio L, Scorza R,

Gabrielli A, Danieli G Coagulative modifications in patients with systemic sclerosis treated with iloprost or nifedipine Ann Ital Med Int 16, 170-174, 2001

79. Catassi C, Fabiani E, Corrao G, Barbato M, De Renzo A, Carella AM, Gabrielli A, Leoni P,

Carroccio A, Baldassarre M, Bertolani P, Caramaschi P, Sozzi M, Guariso G, Volta U, Corazza

GR, and the Italian Working Group on Coeliac Disease and Non-Hodgkin’s Lymphoma. Risk of non-Hodgkin lymphoma in celiac disease. JAMA 287, 1413-9, 2002

80. Chizzolini C, Raschi E, Rezzonico R, Testoni C, Mallone R, Gabrielli A, Facchini A, Del Papa N,

Borghi M O, Dayer JM, Meroni Pl Autoantibodies to fibroblasts induce a proadhesive and pro-inflammatory fibroblast phenotype patients with systemic sclerosis Arthritis Rheum 46, 1602-1613, 2002

81. Giacomelli R, Valentini G, Salsano F, Cipriani P, Sambo P, Conforti ML, Fulminis A, De Luca A,

Farina G, Candela M, Generini S, De Francisci A, Tirri E, Proietti M, Bombardieri S, Gabrielli A,

Matucci Cerinic M. Cyclophosphamide pulse regimen in the treatment of alveolitis in systemic sclerosis. J Rheumatol 29, 731-6, 2002

82. De Rosa FG, Pucillo LP, Di Lullo L, Coviello R, Donnanno S, Laganà B, Quinti I, Candela M,

Gabrielli A, Fiorilli M, Casato M. Influence of age and autoimmuity on liver disease in HCV-associated type II miked cryoglobulinemia. Hum Immunol 63,751-757,2002

83. Dziadzio M, Ghattas L, Scarpelli M, Pomponio G, Gabrielli A. A case of Takayasu’s arteritis with parenchymal pulmonary involvement associated with spondyloarthropathy Clin Exp Rheumatol 21, 413-414, 2003

84. Clements PJ, Becvar R, Drosos AA, Ghattas L, Gabrielli A. Assessment of gastrointestinal involvement in scleroderma. Clin Exp Rheumatol 21, (S) 15-18, 2003

85. Dziadzio M, Giovagnoni A, Pomponio G, Recanatini A, Paci Della Costanza O, Manzin A,

Casagrande W, Gabrielli A. Acute myocarditis associated with adenoviral infection in a patient with sclerodermia. Clin Rheumatol 22, 487-90, 2003

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86. Luchetti MM, Paroncini P, Majilingova P, Frampton J, Mucenski M, Svegliati Baroni S, Sambo P,

Introna M, Gabrielli A. Characterization of the c-myb responsive region of the human type I collagen a2 chain gene. J Biol Chem 278, 1533-41, 2003

87. Dziadzio M, Smith R, Abraham D, Stratton R, Gabrielli A, Black C, Denton C. Serological assessment of type I collagen burden in scleroderma spectrum disorders: a systematic review. Clin Exp Rheumatol 22, 356-367,2004

88. Luchetti MM, Sambo P, Mjilingova P, Svegliati Baroni S, Paroncini P, Peri G, Introna M,

Stoppacciaro A, Mantovani A, Gabrielli A. Scleroderma fibroblasts constitutively express the long pentraxin PTX3. Clin Exp Rheumatol 22, 66-72,2004

89. Del Rosso A, Cinelli M, Guiducci S, Pignone A, Fibbi G, Margheri F, Gabrielli A, Giacomelli R,

Coppini A, Del Rosso M, Matucci Cerinic M. Deflazacort modulates the fibrinolytic pattern and reduces uPA-dependent chemioinvasion and proliferation in rheumatoid arthritis synoviocytes.. Rheumatology 44:1255-62, 2005

90. Monti G, Pioltelli P, Saccardo F, Campanini M, Candela M, Cavallero G, De Vita S, Ferri C,

Mazzaro C, Migliaresi S, Ossi E, Pietrogrande M, Gabrielli A, Galli M, Invernizzi F. Incidence and characteristics of Non-Hodgkin lymphomas in a multicenter case file of patients with hepatitis c virus-related symptomatic mixed cryoglobulinemia. Arch Intern Med 165, 101-105,2005

91. Nesci S, A Iliescu, O Buffi, T Sista, M Luchetti, A. Gabrielli, G Rinaldi. A novel HLA-Cw*6 allele, Cw*160102, identified by clonino and sequencing. Tisse Antigens 65: 580-1 2005

92. Caggiari L, M.P. Simula, A. Marzotto, A. Caragnano, M. Luchetti, A. Gabrielli, V. De Re

Identification of a novel human DRB1*13 allele by sequence-based DRB typing Tissue Antigens 66:246-7. 2005

93. Bandinelli F, Bartoli F,Perfetto F, Del Rosso A, Pignone A, Guiducci S, Fatini C, Generini S,

Gabrielli A, Giacomelli A, Maddali Bongi S, Abbate R, Del Rosso M, Matucci Cerinic M The fibrinolytic system components are increased in Systemic Sclerosis and modulated by Alprostadil (alpha1 ciclodestryn). Clin Exp Rheumatol. 23: 671-7 2005

94. Svegliati Baroni S, Cancello R, Sambo P, Luchetti M, Paroncini P, Orlandini G, Discepoli G,

Paterno’ R, Santillo MR, Cozzo I, Silvana Cassano, Avvedimento EV, Gabrielli A Platelet-derived growth factor and reactive oxygen species (ROS) regulate Ras protein levels in primary human fibroblasts via ERK 1-2. Amplification of ROS and Ras in systemic sclerosis fibroblasts. J Biol Chem 280, 36474-82, 2005

95. Guiducci S, Del Rosso A, Cinelli M, Perfetto F, Livi R, Rossi A, Gabrielli A, Giacomelli R, Iori N,

Fibbi G, Del Rosso M, Matucci Cerinic M. Raloxifene reduces urokinase-type plasminogen activator-dependent proliferation of synoviocytes from patients with rheumatoid arthritis Arthritis Res Ther 7, 1244-1253, 2005.

96. Dziadzio M, Anastassiades CP, Hawkins PN, Potter M, Gabrielli A, Brough GM, Black CM, Denton

CP. From scleredema to AL amyloidosis: disease progression or coincidence? Review of the literature. Clin Rheumatol 25, 3-15, 2005

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97. Svegliati Baroni S, Santillo MR Bevilacqua F, Luchetti M, Spadoni T, Mancini M , Fraticelli P,

Sambo P, Funaro A , Kazlauskas A, Avvedimento EV, Gabrielli A Stimulatory autoantibodies to the PDGF receptor in systemic sclerosis (scleroderma). N Engl J Med 354; 2667-2676,2006

98. Gabrielli A, Svegliati Baroni S, Avvedimento EV. Stimulatory autoantibodies to PDGF receptor in scleroderma (correspondence). N Engl J Med 354, 1279, 2006

99. Del Papa N, Quirici N, Soligo D, Scavullo C,Cortiana M, Borsotti C, Maglione W, Comina DP, Vitali

C, Fraticelli P, Gabrielli A, Cortelezzi A, Lambertenghi-Deliliers G Bone marrow endothelial progenitors are detective in systemic sclerosis . Arthritis Rheum 54; 2605- 2615,2006

100. Moroncini G, Mangieri M , Morbin M, Mazzoleni G, Ghetti B, Gabrielli A, Williamson RA,

Giaccone G, Tagliavini F Pathologic prion protein is specifically recognized in situ by a novel PrP conformational antibody. Neurobiology Dis 23; 7171-724, 2006

101. Cinelli M, Guiducci S; Del Rosso A; Pignone A; Del Rosso M; Fibbi G; Serratì S; Gabrielli

A; Giacomelli R; Piccardi N, Matucci Cerinic, M Piascledine modullates the production of VEGF and TIMP-1 and reduces the invasiveness of rheumatoid arthritis syniviocytes Scan J Rheumatol 2006, 35:346-50, 2006

102. De Re V, Caggiari L, Simula MP, De Vita S, Mazzaro C, Lenzi M, Galli M, Monti G, Ferri C,

Zignego AL, Gabrielli A, Sansonno D, Dammacco F, Libra M, Sacchi N, Talamini R, Spina M,

Tirelli U, Cannizzaro R, Guidoboni M, Dolcetti R. Role of HLA Class II in HCV-related disorders Ann N Y Acad Sci 1107; 308-318,2007

103. Ferrera F, Rizzi M, Sprecacenere B, Balestra P, Sessarego M, Di Carlo A, Filaci G, Gabrielli

A Ravazzolo R Indiveri F AIRE gene polymorphisms in Systemic Sclerosis associated with Autoimmune Thyroiditis Clin Immunol 122; 13-7, 2007

104. Gabrielli A, Svegliati S, Moroncini G,Luchetti M, Tonnini C, Avvedimento EV. Stimulatory auto-antibodies to the PDGF receptor: a link to fibrosis in scleroderma and a pathway for novel therapeutic targets. Autoimmunity Rev 7: 121-126, 2007

105. Svegliati S, Olivieri A, Campelli N, Luchetti M, Poloni A, Trappolini S, Moroncini G,

Bacigalupo A, Leoni P, Avvedimento EV, Gabrielli A. Stimulatory aotoantibodies to PDGF receptor in patients with estensive graft-versus-host disease Blood 110, 237-241,2007

106. Kopecki Z, Luchetti M, Adams D, Strudwick X, Mantamadiotis T, Stoppacciaro A, Gabrielli

A, Ramsay R, Cowin A Collagen loss and impaired woud healing is associated with c- Myb deficiency J Pathol 211; 351: 61, 2007

107. Pomponio G, Tirotta D, Pietracci L, Pasquali S, Pupita G, Raggetti g, Gabrielli A. The diagnostic admission in an internal medicine service: clinical and economic aspects Rec Prog Med 98, 524-33, 2007

108. Gabrielli A, Svegliati S, Moroncini G, Avvedimento EV Pathogenic autoantibodies in systemic sclerosis. Curr Opinion Immunol 19, 640-645,2007

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109. Danieli MG, Calcabrini L, Marchetti AL, Calabrese V, Pettinari L, Massaccesi C,

Gabrielli A, Danieli G La terapia con immunoglobuline endovena nelle malattie autoimmuni. Rec Prog Med 98, 322-326, 2007

110. De Re V, Caggiari L, De Vita S, Mazzaro C, Lenzi M, Galli M, Monti G, Ferri C,

Zignego AL, Gabrielli A, Sansonno D, Dammacco F, Libra M, Sacchi N, Talamini R,

Spina M, Cannizzaro R, Guidoboni M, Dolcetti R Genetic insights into the disease mechanisms of type II mixed cryoglobulinemia induced by hepatitis C virus. Dig Liver Dis. 39 (Suppl 1), S65-71, 2007

111. Denton CP, Pope JE, Peter HH, Gabrielli A, Boonstra A, van den Hoogen F,

Riemkasten G, De Vita S, Morganti A, Berkani O, Guillevin L. Long-term effects of Bosentan on quality of life, survival, safety and tolerability in pulmonary arterial hypertension related to connective tissue diseases. Ann Rheum Dis 67, 1222-28, 2008

112. Gabrielli A, Svegliati S, Moroncini G, Pomponio G, Santillo M, Avvedimento EV Oxidative stress and the pathogenesis of scleroderma: the Murrell’s hypothesis revisited. Sem Immunopathol 30, 329-37, 2008

113. Walker UA, Tyndall A, Czirják L, Denton C, Farge-Bancel D, Kowal-Bielecka O, Müller-

Ladner U, Matucci-Cerinic M, Gabrielli A and EUSTAR Co-authors Geographic variation of disease manifestations in systemic sclerosis - a report from the EULAR Scleroderma Trials And Research (EUSTAR) group data base. Ann Rheum Dis 68, 856-62, 2009

114. Distler HWJ, Allanore Y, Avouac J, Giacomelli R, Guiducci S, Moritz F, Akhmetshina A,

Walzer U, Gabrielli A, Muller-Landner U, Tyndal A, Matucci-Cerinic M, Distler O. EUSTAR statement and recommendations on endothelial precursor cells in systemic sclerosis. Ann Rheum Dis 68, 163-168, 2009

115. Krieg T, Hunzelmann N, Gabrielli A, Jablonska S. European Dermatology Forum: skin diseases in Europe. Skin diseases with a high public health impact: scleroderma.Scleroderma. Eur J Dermatol. 18, 213-4, 2008

116. Gabrielli A, Avvedimento EV, Krieg T. Scleroderma. N Engl J Med 360, 1989-2003, 2009

117. Danieli MG, Spalletta C, Moretti R, Calabrese V, Marchetti A, Gabrielli A, Logullo F. Immunosuppressant treatment in refractory myositis. Our experience. Recenti Prog Med 100, 451-7, 2009

118. Danieli MG, Calcabrini L, Calabrese V, Marchetti A, Logullo F, Gabrielli A. Intravenous immunoglobulins add on treatment with mycophenolate mofetil in severe myositis. Autoimmunity Rev 9, 124-7, 2009

119. Danieli MG, Marchetti A, Monteforte F, Calabrese V, Pettinari L, Gabrielli A. Splenic microcalcifications in systemic lupus erythematosus. Lupus 18, 570-1, 2009

120. Martucci F, Acutis P, Mazza M, Nodari S, Colussi S, Corona C, Barocci S, Gabrielli A,

Caramelli M, Casalone C, Moroncini G. Detection of typical and atypical bovine spongiform encephalopathy and scrapie prion strains by prion protein motif-grafted antibodies. J Gen Virol 90,1048-53, 2009

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121. Giuliodori G, Fraticelli P, bartolini M, Cagnetti C, Baruffaldi R, Rocchi MBL, Provinciali L,

Gabrielli A, Silvestrini M. Cognitive and cerebral hemodynamic impairment in scleroderma patients. Eur J Neur 16,1285-90, 2009

122. Olivieri A, Locatelli F, Zecca M, Sanna A, Cimminiello M, Raimondi R, Gini G, Mordini N,

Balduzzi A, Leoni P, Gabrielli A, Bacigalupo A. Imatinib for refractory chronic Graft-versus-Host disease with fibrotic features. Blood 114, 700-718, 2009

123. Gabrielli A, Moroncini G, Avvedimento EV. Autoantibodies against PDGF receptor in scleroderma, comment on the articles by Classen et al and Loizos et al. Arthritis Rheum 60, 3521-3522, 2009

124. Avvedimento EV, Gabrielli A Stiff and tight skin: a rear window into fibrosis without inflammation. Science Transl Med 2: 23ps13, 2010

125. Avouac J, Walker U, Tyndall A, Gabrielli A et al Characteristics of joint involvement and

relationships with systemic inflammation in systemic sclerosis: results from the EULAR Scleroderma Trial and Research Group (EUSTAR) database. J Rheumatol. 37,1488-501, 2010

126. Bocchino ML, Agnese S, Fagone E, Svegliati S, Grieco D, Vancheri C, Gabrielli A,

Sanduzzi A, Avvedimento EV. Involvement of reactive oxygen species in the phenotypic characterization of primary lung fibroblasts from idiopathic pulmonary fibrosis patients PLoS One 2010; 5: e14003

127. Avouac J, Fransen J, Walker UA, Riccieri V, Smith V, Muller C, Miniati I, Tarner IH,

Randone SB, Cutolo M, Allanore Y, Distler O, Valentini G, Czirjak L, Muller-Ladner U, Furst DE,

Tyndall A, Matucci-Cerinic M, Gabrielli A. EUSTAR Group Preliminary criteria for the very early diagnosis of systemic sclerosis: results of a Delphi consensus study from EULAR scleroderma trials and research group. Ann Rheum Dis 70, 476-81 2011

128. Smaldone S, Olivieri J, Gusella L, Moroncini G, Gabrielli A Ramirez F. Ha-Ras stabilization

mediates pro-fibrotic signals in dermal fibroblasts Fibrogenesis & Tissue Repair 4, 8, 2011

129. Herrick AL, van den Hoogen F, Gabrielli A, Tamimi N, Reid C, O’Connell D, Vazquez-Abad

MD, Denton CP. Modified-release sildenafil reduces Raynaud’s attack frequency in limited cutaneous systemic sclerosis. Arthritis Rheum 63, 775-782, 2011

130. Pietrogrande M, De Vita S, Zignego AL, Pioltelli P, Sansonno D, Sollima S, Atzeni F,

Saccardo F, Quartuccio L, Bruno S, Bruno R, Campanini M, Candela M, Castelnovo L, Gabrielli A,

Gaeta GB, Marson P, Mascia MT, Mazzaro C, Mazzotta F, Meroni P, Montecucco C, Ossi E,

Piccinino F, Prati D, Puoti M, Riboldi P, Riva A, Roccatello D, Sagnelli E, Scaini P, Scarpato S,

Sinico R, Taliani G, Tavoni A, Bonacci E, Renoldi P, Filippini D, Sarzi-Puttini P, Ferri C, Monti G,

Galli M. Recommendations for the management of mixed cryoglobulinemia syndrome in epatitis C virus- infected patients. Autoimmunity Rev 10, 444-454, 2011

131. Danieli MG, Pettinari L, Moretti R, LoGullo F, Gabrielli A Subcutaneous immunoglobulins in

polymyositis and dermatomyositis: a novel application. Autoimmunity Rev 10, 144-149, 2011

132. Fransen J, Popa-Diaconu D, Hesselstrand R, Carreira P, Valentini G, Berena L, Airo P,

Inanc M, Ullman S, Balbir-Gurman A, Sierakowski S, Allanore Y, Czirjak L, Riccieri V, Giacomelli

R, Gabrielli A, Riemekasten G, Matucci-Cerinic M, Farge D, Hunzelmann N, Van den Hoogen FHJ,

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Vonk MC Clinical prediction of 5-year survival in systemic sclerosis: validation of a simple prognostic model in EUSTAR centres Ann Rheum Dis 70, 1788-1792, 2011

133. De Vita S, Soldano F, Isola M, Monti G, Gabrielli A, Tzioufas A, Ferri C, Ferraccioli GF,

Quartuccio L, Corazza L, De Marchi G, Casals MR, Voulgarelis M, Lenzi M, Saccardo F, Fraticelli

P, Mascia MT, Sansonno D, Cacoub P, Tomsic M, Tavoni A, Pietrogrande M, Zignego AL,

Scarpato S, Mazzaro C, Pioltelli P, Steinfeld S, Lamprecht P, Bombardieri S, Galli M Preliminary classification criteria for the cryoglobulinemic vasculitis. Ann Rheum Dis 70, 1183-1190, 2011

134. Mazzaro C, Monti G, Saccardo F, Zignego AL, Ferri C, De Vita S, Gabrielli A, Lenzi M,

Donada C, Galli M, Pietrogrande M, Pozzato G Efficacy and safety of peginterferon alfa-2b plus ribavirin for HCV-positive mixed cryoglobulinemia: a multicentre open-label study. Clin Exp Rheumatol 29, 933-41, 2011

135. Fransen J, Johnson SR, van den Hoogen F, Baron M, Allanore Y, Denton C, Furst D

Carreira P, Czirjak L, Distler O, , Gabrielli A, Herrick A, Inanc M, Kahaleh B, Kowal-Bielecka O,

Medsger T, Mueller-Ladner U, Riemekasten G, Sierakowski S, Valentini G, Veale D, Vonk M,

Chung L, Clements P, Collier D, Csuka ME, Jimenez S, Merkel P, Seibold J, Silver R, Steen V,

Tyndall A, Matucci-Cerinic M, Pope JE, Khanna D. Items for developing revised classification criteria in systemic sclerosis: results of a consensus exercise. Arthritis Care & Res 64, 351-357, 2012,

136. De Vita S, Quartuccio L, Isola M, Mazzaro C, Scaini P, Lenzi M, Campanini M, Naclerio

C,Tavoni A, Pietrogrande M, Ferri C, Mascia MT, Masolini P, Zabotti A, Maset M, Roccatello D,

Zignego AL, Pioltelli P, Gabrielli A, Filippini D, Perrella O, Migliaresi S, Galli M, Bombardieri S,

Monti G. A randomized controlled trial of rituximab for the treatment of severe cryoglobulinemic vasculitis. Arthritis Rheum. 64, 843-53, 2012

137. Bartoloni E, Alunno A, Bistoni O, Bizzaro N, Migliorini P, Morozzi G, Doria A, Mathieu A,

Lotzinker M, Allegri F, Riccieri V, Alpini C, Gabrielli A, Tamponio M, Gerli R Diagnostic value of anti-mutated citrullinated vimentin in comparison to anti- cyclic citrullinated peptide and anti-viral citrullinated peptide 2 antibodies in rheumatoid arthritis: an Italian multicentric study and review of the literature. Autoimmunity Rev 11, 815-820, 2012

138. Quartuccio L, Isola M, Corazza L, Maset M, Monti G, Gabrielli A, Tzioufas A, Ferri C,

Ferraccioli G, Ramos-Casals M, Voulgarelis M, Lenzi M, Mascia MT, Sansonno D, Cacoub P,

Tomsic M, Tavoni A, Pietrogrande M, Zignego AL, Scarpato S, Pioltelli P, Steinfeld S, Lamprecht

P, Bombardieri S, Galli M, De Vita S. Performance of the preliminary classification criteria for cryoglobulinaemic vasculitis and clinical manifestations in hepatitis C virus-unrelated cryoglobulinaemic vasculitis. Clin Exp Rheumatol 30, 48-52, 2012

139. Gabrielli A, Svegliati S, Moroncini G, Amico D New Insights into the role of oxidative stress in scleroderma fibrosis Open J Rheumatol 6, 87-95, 2012

140. Bandinelli F, Del Rosso A, Gabrielli A, Giacomelli R, Bartoli F, Guiducci S, Matucci Cerinic

M. CCL2, CCL3 and CCL5 chemokines in systemic sclerosis the correlation with SSc clinical features and the effect of prostaglandin E1 treatment. Clin Exp Rheumatol 30, S44-9, 2012

141. Danieli MG, Moretti R, Pettinari L, Gabrielli A.Subcutaneous immunoglobulins in ocular myositis. Rheumatology (Oxford) 51, 764-5, 2012

142. Denton CP, Krieg T, Guillevin L, Schwierin B, Rosenberg D, Silkey M, Zultak M, Gabrielli A

,Matucci-Cerinic M et al. Demographic, clinical and antibody characteristics of patients with digital ulcers in systemic sclerosis: data from the DUO Registry. Ann Rheum Dis. 71, 718-21, 2012

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143. Menditto VG, Lucci M, Polonara S, Pomponio G, Gabrielli A. Management of minor head injury in patients receiving oral anticoagulant therapy: a prospective study of a 24-hour observation protocol. Ann Emerg Med 59, 451-5, 2012

144. Bonifazi M, Tramacere I, Pomponio G, Gabrielli B, Avvedimento EV, La Vecchia C, Negri E,

Gabrielli A. Scleroderma and cancer risk: systematic review and meta-analysis of observational studies” Rheumatology 52, 143-54, 2013

145. Orciani M, , Svegliati S, Gorbi S, Spadoni T, Lazzarini R, Regoli F, Di Primio R, Gabrielli A

Alterations of ROS pathway in scleroderma begin at stem cell level. J Biol Reg Homeost. Agents 27,

211-24, 2013

146. van den Hoogen F, Khanna D, Fransen J, Johnson SR, Baron M, Tyndall A, Matucci-

Cerinic M, Naden R, Medsger TA Jr, Carreira P, Riemekasten G, Clements P, Denton C, Distler O,

Allanore Y, Furst DE, Gabrielli A, Mayes M, van Laar J, Seibold JR, Czirjak L, Steen V, Inanc M,

Kowl-Bielecka O, Müller-Ladner U, Valentini G, Veale D, Vonk M, Walker U, Chung L, Collier D,

Csuka ME, Fessler BJ, Guiducci S, Herrick A, Hsu V, Jimenez S, Kahaleh B, Merkel P,

Sierakowski S, Silver R, Simms R, J Varga J, Pope JE. 2013 Classification Criteria for Systemic Sclerosis: An American College of Rheumatology/European League against rheumatism Collaborative Initiative Arthritis Rheum 65, 2737-47, 2013

147. Campanati A, Moroncini G, Ganzetti G, Pozniak KN, Goteri G, Giuliano A, Martina E,

Liberati G, Gabrielli A, Offidani A Adalimumab modulates angiogenesis in psoriatic skin. Eur J Inflamm 1, 489-498, 2013

148. Moroncini G, Mori S, Tonnini C, Gabrielli A. Role of viral infections in the etiopathogenesis of systemic sclerosis. Clin Exp Rheumatol 31, 3-7, 2013

149. Cuccioloni M, Moroncini G, Mozzicafreddo M, Pozniak KN, Nacci G, Grieco A, Paolini C,

Tonnini C, Funaro A, Angeletti A, Gabrielli A. Biosensor-based Binding Assay for Platelet-Derived Growth Factor Receptor-α Autoantibodies in Human Serum J Anal Bioanal Tech S7: 010; 2013

150. van den Hoogen F, Khanna D, Fransen J, Johnson SR, Baron M, Tyndall A, Matucci-

Cerinic M, Naden R, Medsger TA Jr, Carreira P, Riemekasten G, Clements P, Denton C, Distler O,

Allanore Y, Furst DE, Gabrielli A, Mayes M, van Laar J, Seibold JR, Czirjak L, Steen V, Inanc M,

Kowl-Bielecka O, Müller-Ladner U, Valentini G, Veale D, Vonk M, Walker U, Chung L, Collier D,

Csuka ME, Fessler BJ, Guiducci S, Herrick A, Hsu V, Jimenez S, Kahaleh B, Merkel P,

Sierakowski S, Silver R, Simms R, J Varga J, Pope JE. 2013 Classification Criteria for Systemic Sclerosis: An American College of Rheumatology/European League against rheumatism Collaborative Initiative. Ann Rheum Dis 72:1747-55, 2013

151. Olivieri A, Cimminiello MMC, Corradini P, Mordini N, Fedele R, Selleri C, Onida F, Patriarca

F, Pavone E, Svegliati S, Gabrielli A, Bresciani P, Nuccorini R, Pascale S, Coluzzi S, Pane F,

Poloni A, Olivieri J, Pane F, Leoni P, Bacigalupo A Long term outcome and prospective validation of NIH response criteria in 39 patients receiving Imatinib for steroid-refractory chronic GVHD. Blood 122, 4111-8, 2013

152. Fattal I, Shental N, Molad Y, Gabrielli A, Pokroy-Shapira E, Oren S, Livneh A, Langevitz P,

Pauzner R, Sarig O, Gafter U, Domany E, Cohen IR. Epstein-Barr virus antibodies mark systemic lupus erythematosus and scleroderma patients negative for anti-DNA. Immunology. 141, 276-85. 2014

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153. Danieli MG, Moretti R, Gambini S, Paolini L, Gabrielli A Open-label study on treatment with 20% subcutaneous IgG administration in Polymyositis and Dermatomyositis. Clin Rheumatol 33, 531-6, 2014

154. Danieli MG, Gelardi C, Pedini V, Moretti R, Gabrielli A, Logullo F. Subcutaneous IgG in immune-mediate diseases: proposed mechanisms of action and literature review. Autoimmun Rev 13,1182-8, 2014

155. Moroncini G, Pomponio G, Dziadzio M, Paci della Costanza O, Alessandra Pierfederici A,

Ferretti L, Giuseppe Pupita G, Luca Salvolini L, Andrea Giovagnoni A, Gabrielli A Myocardial perfusion defects in scleroderma detected by contrast-enhanced cardiovascular magnetic resonance. La Radiologia Medica 119, 885-94, 2014

156. Donati A, Damiani E, Luchetti MM, Domizi R, Scorcella C, Carsetti A, Gabbanelli V, Carletti

P, Bencivenga R, Vink H, Adrario E, Piagnerelli M, Gabrielli A, Pelaia P, Ince C. Microcirculatory effects of the transfusion of leukodepleted or non-leukodepleted red blood cells in septic patients: a pilot study. Crit Care 18, R33, 2014

157. Maurer B, Graf N, Michel BA, Müller-Ladner U, László Czirják, Denton C, Tyndall A, Baron

M, Metzig C, Lanius V, Khanna D, Distler O Gabrielli A and EUSTAR co-authors Prediction of worsening of skin fibrosis in patients with diffuse cutaneous systemic sclerosis using the EUSTAR database. Ann Rheum Dis 74, 1124-31, 2015

158. Johnson SR, Naden RP, Fransen J, van den Hoogen F, Pope JE, Baron M, Tyndall A,

Matucci-Cerinic M, Denton CP, Distler O, Gabrielli A, van Laar J, Mayes M, Steen V, Seibold JR,

Clements P, Medsger TAJr17, Carreira PE, Riemekasten G, Chung L,. Fessler BJ, Merkel P, Silver

R, Varga J, Allanore Y, Mueller-Ladner U, Vonk MC, Walker UA, Cappelli S, Khanna D. Multicriteria decision analysis methods with 1000Minds for developing systemic sclerosis classification criteria J Clin Epidemiol 67, 706-14, 2014

159. Quartuccio L, Isola M, Corazza L, Ramos-Casals M, Retamozo S, Ragab GM, Zoheir MN,

El-Menyawi MA, Salem MN, Sansonno D, Ferraccioli G, Gremese E, Tzioufas A, Voulgarelis M,

Vassilopoulos D, Scarpato S, Pipitone N, Salvarani C, Guillevin L, Terrier B, Cacoub P, Filippini

D, Saccardo F, Gabrielli A, Fraticelli P, Sebastiani M, Tomsic M, Tavoni A, Mazzaro C, Pioltelli P,

Nishimoto N, Scaini P, Zignego AL, Ferri C, Monti G, Pietrogrande M, Bombardieri S, Galli M, De

Vita S. Validation of the classification criteria for cryoglobulinaemic vasculitis.Rheumatology (Oxford). 53, 2209-13, 2014

160. EULAR Textbook on Systemic Sclerosis Ed Eric Hachulla, L Czirjak BMJ Autoantibodies, autoimmunity Masataka Kuwana & Armando Gabrielli pp 88-96, 2014

161. Svegliati S, Marrone G, Pezone A, Spadoni T, Grieco A, Moroncini G, Grieco D, Vinciguerra

M, Agnese S, Jungel A, Distler O., Musti AM, Gabrielli A, Avvedimento EV. Oxidative DNA damage induces the ATM-mediated transcriptional suppression of the WNT inhibitor WIF-1 in systemic sclerosis and fibrosis. Science Signal 7,ra84, 2014

162. Nobili L. Albani L, Gabrielli A, Moroncini G. Reactivation of hepatitis B virus infection

associated with anti- tumor necrosis factor –therapy. J Antivir Antiretrovir 6, 3, 2014

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163. Danieli MG, Gambini S, Pettinari L Logullo F, Veronesi G, Gabrielli A. Impact of treatment on survival in polymyositis and dermatomyositis. A single-Centre long term follow-up study. Autoimmunity Rev 13, 1048-54, 2014

164. Fraticelli P, Gabrielli B, Pomponio G, Valentini G, Bosello S, Riboldi P, Gerosa M, Faggioli P,

Giacomelli R, Del Papa N, Gerli R, Lunardi C, Bombardieri S, Malorni W, Corvetta A, Moroncini G,

Gabrielli A on behalf of “Imatinib in Scleroderma Italian Study Group” Low-dose Oral Imatinib in the Treatment of Systemic Sclerosis Interstitial Lung Disease unresponsive to cyclophosphamide. A Phase II Pilot Study. Arthritis Res Therapy 16:R144, 2014

165. Lonati PA, Brembilla NC, Montanari E, Fontao L, Gabrielli A, Vettori S, Valentini G, Laffitte

E; Kaya G, Meroni PL, Chizzolini C High IL-17E and low IL-17C dermal expression identifies a fibrosis-specific motif common to morphea and systemic sclerosis". PLoS one 9, e105008, 2014

166. Fattal I, Rimer J, Shental N, Molad Y, Gabrielli A, Livneh A, Sarig O, Goldberg I, Gafter U,

Domany E, Cohen IR. Pemphigus vulgaris is characterized by low IgG reactivities to specific self-antigens along with high IgG reactivity to desmoglein 3. Immunology 143:374-80, 2014

167. Del Papa N, Di Luca G, Sambataro D, Zaccara E, Maglione W, Gabrielli A, Fraticelli P,

Moroncini G, Beretta L, Santaniello A, Sambataro G, Ferraresi R, Vitali C. Reply to J. Magalon et al. Cell Transplant 24, 2669-70, 2015

168. Moroncini G, Grieco A, Nacci G, Paolini C, Tonnini C, Katarzyna N. Pozniak1, Cuccioloni M,

Mozzicafreddo M, Silvia Svegliati S, Angeletti M, Kazlauskas A, Avvedimento EV, Funaro A,

Gabrielli A. Epitope specificity determines pathogenicity and detectability of anti-PDGFR autoantibodies in systemic sclerosis Arthritis Rheumatol 67; 1891–1903; 2015

169. Jordan S, Distler JHW, Maurer B, Huscher D, van Laar JM, Allanore Y, Distler O, , Gabrielli

A EUSTAR rituximab study group. Effects and safety of Rituximab (RTX) in Systemic sclerosis: an analysis from the European Scleroderma Trial and Research group (EUSTAR). Ann Rheum Dis 74, 1188-94, 2015

170. Fattal I, Shental N, Ben-Dor S, Molad Y, Gabrielli A, Pokroy-Shapira E, Oren S, Livneh A,

Langevitz P, Zandman-Goddard G, Sarig O, Margalit R, Gafter U, Domany E, Cohen IR. Guanine polynucleotides are self-antigens for human natural autoantibodies and are significantly reduced in the human genome. Immunology 146:401-10, 2015

171. Bonifazi M, Francesca Bravi F, Gasparini S, La Vecchia C, Gabrielli A, Wells A, Renzoni E Sarcoidosis and cancer risk: systematic review and meta-analysis of observational studies. Chest 147, 778-91,2015

172. Damiani E, Adrario E, Luchetti MM, Scorcella C, Carsetti A, Mininno N, Pierantozzi S,

Principi T, Strovegli D, Bencivenga R, Gabrielli A, Romano R, Pelaia P, Ince C, Donati A. Plasma free haemoglobin and microcirculatory response to fresh or old red blood transfusions in sepsis. PLoS One 10, e0122655, 2015

173. Donzelli G, Carnesecchi G, Amador C, di Tommaso M, Filippi L, Caporali R, Codullo V,

Riccieri V, Valesini G, Gabrielli A, Bagnati R, McGreevy KS, De Masi S, Matucci Cerinic M Fetal programming and systemic sclerosis. Am J Obstet Gynecol 213: 839.e1-8, 2015

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174. Del Papa N, Di Luca G, Sambataro D, Zaccaro E, Maglione W, Gabrielli A, Fraticelli P,

Moroncini G, Beretta L, Santaniello A, Sambataro G, Vitali C. Regional implantation of autologous adipose tissue-derived cells induces a prompt healing of long-lasting indolent digital ulcers in patients with Systemic sclerosis Cell transplant 24, 2297-305, 2015

175. Tedesco S, Postacchini L, Manfredi L, Goteri G, Luchetti MM, Festa A, Gabrielli A,

Pomponio G Successful treatment of a Caucasian case of multifocal Castleman’s disease with TAFRO Syndrome with a pathophysiology targeted therapy. A case report. Experimental Hematology & Oncology 4:3, 2015

176. Iudici M, Moroncini G, Cipriani P, Giacomelli R, Gabrielli A, Valentini G Where are we going in the management of interstitial lung disease in patients with systemic sclerosis? Autoimmun Rev. 14, 575-578, 2015

177. Fraticelli P, De Vita S, Franzolini N, Svegliati S, Scott C, Tonnini C, Spadoni T, Gabrielli B,

Pomponio G, Moroncini G, Gabrielli A Reduced type I collagen gene expression by skin fibroblasts of

patients with systemic sclerosis after one treatment course with rituximab. Clin Exp Rheumatol 33, 160-167,

2015

178. Spadoni T, Svegliati Baroni S, Amico D, Albani L, Moroncini G, Avvedimento EV, Gabrielli A. A

reactive oxygen species-mediated loop maintains the increased expression of NADPH oxidases 2 and 4 in

skin fibroblasts from patients with systemic sclerosis. Arthritis Rheumatol 67, 1611–1622, 2015

179. Amico D, Spadoni T, Rovinelli M, Serafini M, D'Amico G, Campelli N, Svegliati S, Gabrielli

A. Intracellular free radical production by peripheral blood T lymphocytes from patients with Systemic Sclerosis: role of NADPH oxidase and ERK1/2. Arthritis Res Therapy 17, 68, 2015

180. Olivieri J, Manfredi L, Postacchini L, Tedesco S, Leoni P, Gabrielli A, Rambaldi A,

Bacigalupo A, Olivieri A, Pomponio G. Consensus recommendations for improvement of unmet clinical needs? The example of chronic graft-versus-host disease: a systematic review and meta-analysis. Lancet Haematol 2, e297-305, 2015

181. Quartuccio L. et al Quartuccio L, Zuliani F, Corazza L, Scaini P, Zani R, Lenzi M, Tavoni A,

Sebastiani M, Baldovino S, Urraro T, Saccardo F, Sbreglia C, Mazzaro C, Pioltelli P, Fraticelli P,

Filippini D, Gabrielli A, Perrella O, Scarpato S, Roccatello D, Zignego AL, Ferri C, Bombardieri S,

Pietrogrande M, Monti G, Galli M, De Vita S. Retreatment regimen of rituximab monotherapy given at the relapse of severe HCV-related cryoglobulinemic vasculitis: Long term follow up of a randomized controlled multicenter study J of Autoimmunity 63, 88-93, 2015

182. Luchetti MM , Moroncini G, Escamez MJ, Svegliati Baroni S, Spadoni T, Grieco A, Paolini

C, Avvedimento EV, Larcher F, Del Rio M, Gabrielli A Induction of scleroderma fibrosis in skin-humanized mice by administration of anti-Platelet-Derived Growth Factor receptor agonistic autoantibodies. Arthritis Rheumatol 68, 2263-73, 2016

183. Luchetti MM, Balloni A, Gabrielli A. Biologic Therapy in Inflammatory and Immunomediated Arthritis: Safety Profile.Curr Drug Saf. 11:22-34, 2016

184. Iudici M, Moroncini G, Cipriani P, Giacomelli R, Gabrielli A, Valentini G. Comment on

'Where are we going in the management of interstitial lung disease in patients with systemic sclerosis?'. Autoimmun Rev 15: 202, 2016

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185. Brembilla NC, Dufour AM, Alvarez M, Hugues S, Montanari E, Truchetet ME, Lonati P,

Fontao L, Gabrielli A, Vettori S, Valentini G, Boehncke WH, Meroni P, Chizzolini C. IL-22 capacitates dermal fibroblast responses to TNF in scleroderma. Ann Rheum Dis. 75:1697-705; 2016

186. Danieli MG, Gelardi C, Guerra F, Cardinaletti P, Pedini V, Gabrielli A. Cardiac involvement in polymyositis and dermatomyositis. Autoimmun Rev 15, 462-5, 2016.

187. López-Isac E, Campillo-Davo D, Bossini-Castillo L, Guerra SG, Assassi S, Simeón CP,

Carreira P, Ortego-Centeno N, García de la Peña P; Spanish Scleroderma Group, Beretta L,

Santaniello A, Bellocchi C, Lunardi C, Moroncini G, Gabrielli A, Riemekasten G, Witte T,

Hunzelmann N, Kreuter A, Distler JH, Voskuyl AE, de Vries-Bouwstra J, Herrick A, Worthington J,

Denton CP, Fonseca C, Radstake TR, Mayes MD, Martín J Influence of TYK2 in Systemic Sclerosis susceptibility: a new locus in the IL-12 pathway" Ann Rheum Dis 75, 1521-6, 2016

188. López-Isac E, Martín JE, Assassi S, Simeón CP, Carreira P, Ortego-Centeno N, Freire M,

Beltrán E, Narváez J, Alegre-Sancho JJ; Spanish Scleroderma Group, Fernández-Gutiérrez B,

Balsa A, Ortiz AM, González-Gay MA, Beretta L, Santaniello A, Bellocchi C, Lunardi C, Moroncini

G, Gabrielli A, Witte T, Hunzelmann N, Distler JH, Riekemasten G, van der Helm-van Mil AH, de

Vries-Bouwstra J, Magro-Checa C, Voskuyl AE, Vonk MC, Molberg Ø, Merriman T, Hesselstrand

R, Nordin A, Padyukov L, Herrick A, Eyre S, Koeleman BP, Denton CP, Fonseca C, Radstake TR,

Worthington J, Mayes MD, Martín J. Brief report: IRF4 newly identified as a common susceptibility locus for Systemic Sclerosis and Rheumatoid Arthritis in a cross-disease meta-analysis of Genome-wide Association Studies. Arthritis Rheumatol 68, 2338-44,2016

189. Fraticelli P, Kafyeke A, Mattioli M, Martino GP, Murri M, Gabrielli A. Idiopathic hypereosinophilic syndrome presenting with severe vasculitis successfully treated with Imatinib. World Journal of Clin Cases In Press

190. Fraticelli P, Bagnarelli P, Tarantino G, Martino GP, Benfaremo D, Nobili L , Mandolesi A,

Barbisan F, Marinelli K, Mattioli M, Murri, M, Gabrielli A Chronic hepatitis E in a patient treated with rituximab and mycophenolate mofetil for Sjogren’s syndrome Rheumatology In Press

191. Bianchi T, Wolcott RD, Peghetti A, Leaper D, Cutting K, Polignano R, Rosa Rita Z,

Moscatelli A, Greco A, Romanelli M, Pancani S, Bellingeri A, Ruggeri V, Postacchini S, Tedesco

S, Manfredi L, Camerlingo M, Rowan S,Gabrielli A Pomponio G, Recommendations for the management of biofilm: a consensus document Journal of Wound Care 25, 305-17, 2016

192. Moroncini G, Albani L, Nobili L, Gabrielli A. Biologic Therapy in Inflammatory Immunomediated Systemic Diseases: Safety Profile. Curr Drug Saf 11: 44-6, 2016

193. Salaffi F, Fraticelli P, Carotti M, Fischetti C, Di Carlo M, Giuseppetti GM, Gabrielli

A. Internal and external responsiveness of computer-aided quantification of interstitial lung disease from high resolution computed tomogrophy images in Systemic sclerosis: comparison with visual reader-based score. Sarcoidosis vasculitis and diffuse lung disease In Press

194. Ciccia F, Guggino G, Rizzo, Alessandro R, Luchetti MM, Milling S, Saieva L,

Cypers H, Stampone T, Gabrielli A, Fasano A, Elewaut D, Triolo G. Dysbiosis and Zonulin up-regulation alter gut epithelial and vascular barriers in patients with Ankylosing Spondylitis. Annals Rheum Dis In Press

195. Svegliati S, Amico D, Spadoni T, Fischetti C, Finke D, Moroncini G, Paolini C,

Tonnini C, Grieco A, Rovinelli M, Gabrielli A. Agonistic anti-PDGF receptor autoantibodies

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from patients with Systemic sclerosis impact human pulmonary artery smooth mucle cells in vitro. Front Immunol In Press

196. Veronika K. Jaeger1, Oliver Distler2, Britta Maurer2, Laszlo Czirják3, Veronika Lóránd3,

Gabriele Valentini4, Serena Vettori4, Francesco Del Galdo5, Giuseppina Abignano5, Christopher

Denton6, Svetlana Nihtyanova6, Yannick Allanore7, Jerome Avouac7, Gabriele Riemekasten8, Elise

Siegert9, Dörte Huscher10, Marco Matucci-Cerinic11, Serena Guiducci11, Marc Frerix12, Ingo H.

Tarner12, Beata Garay Toth13, Lidia Ananieva14, Carina Mihai15, Franco Cozzi16, Sule Yavuz17,

Nicolas Hunzelmann18, Simona Rednic19, Alessandra Vacca20, Tim Schmeiser21, Valeria Riccieri22,

Paloma García de la Peña Lefebvre23, Armando Gabrielli24, Brigitte Krummel-Lorenz25, Duska

Martinovic26, Codrina Ancuta27, Vanessa Smith28, Ulf Müller-Ladner12, Ulrich A. Walker1 on behalf

of the DeSScipher Consortium and contributing EUSTAR centre Functional disability and its predictors in systemic sclerosis: a study from the DeSScipher project within the EUSTAR group Rheumatology In Press

197. Guerra F et al "Subclinical cardiac dysfunction in polymyositis and dermatomyositis: a speckle tracking case-control study" J Rheumatol In Press

198. Fraticelli P, Cardinali M, Biondi L, benfaremo D, Mattioli M, Mazzucchelli’ R, Montironi R,

Gabrielli A. A painful diagnosis. Intern Emerg Med In Press

199. Sindhu J, Soowamber, Medha; Fransen, Jaap; Khanna, Dinesh; Van Den Hoogen, Frank;

Baron, Murray; Matucci Cerinic, Marco; Denton, Christopher; Medsger Jr., Thomas; Carreira,

Patricia; Riemekasten, Gabriela; Distler, JHW; Gabrielli, Armando; Steen, Virginia; Chung,

Lorinda; Silver, Richard ; Varga, John; Mueller-Ladner, Ulf; Vonk, Madelon; Walker, Ulrich;

Wollheim, Frank; Herrick, Ariane; Furst, DE; Czirjak, Laszlo; Kowal-Bielecka, Otylia ; Del Galdo,

Francesco ; Cutolo, Maurizio; Hunzelmann, Nicolas; Murray, Charles; Foeldvari, Ivan; Mouthon,

L; Damjanov, Nemanja; Kahaleh, Bashar; Frech, TM; Assassi, Shervin; Saketkoo, Lesley Ann ;

Pope, Janet'. There is a need for new systemic sclerosis subset criteria. A content analytic approach. Scand J Rheumatol In press

200. Campanati A, Benfaremo D, Luchetti MM, G. Ganzetti G, A. Gabrielli A,, Offidani A Certolizumab pegol for the treatment of psoriasis. Expert Opinion on Biological Therapy In Press

201. Spadoni T, Mancini M, Luchetti MM, Svegliati Baroni S, Gabrielli A. Anti PDGF receptor autoantibodies isolated from scleroderma patients induce collagen matrix contraction by human dermal fibroblasts. J Dermatology and Clinical Research In Press

202. Danieli MG et al Subcutaneous IgG in the Myositis Spectrum Disorders. Current Rheumatology

Reviews In Press

203. Galli M. Oreni L, Saccardo F, Castelnovo L, Filippini D, Marson P, Mascia MT,

Mazzaro C, Origgi L, Ossi E, Pietrogrande M, Pioltelli P, Quartuccio L, Scarpato S,

Sollima S, Riva A, Fraticelli P, Zani R, Giuggioli D, Sebastiani M, Sarzi Puttini P,

Gabrielli A, Zignego AL, Scaini P, Ferri C, De Vita S, Monti G. HCV-unrelated cryoglobulinemic vasculituis: the results of a prospective observational study by the Italian group for the study of cryoglobulinemias (GISC) Clin Exp Rheumatol In Press

204. Moroncini G, Cuccioloni M, Mozzicafreddo M, Pozniak KN, Grieco A, Paolini C,

Tonnini C, Spadoni T, Svegliati S, Funaro A, Angeletti M, Gabrielli A. Characterization of binding and quantification of human antibodies to PDGFRa using a biosensor-based approach. Analytical Biochem In Press

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205. Luchetti MM , Larcher F, Moroncini G, Svegliati S, Avvedimento EV, , Gabrielli A Induction of scleroderma fibrosis in skin-humanized mice by administration of anti-Platelet-Derived Growth Factor receptor agonistic autoantibodies. Arthritis Rheumatol (Correspondence) In Press