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La Sinergia fra produttori di strumenti e mondo scientifico

Nicola La MonicaSenior Sales & Support Manager,Italy, Spain & Portugal

2 © 2011 AB SCIEX

ACQUA e LC-MS: come le innovazioni nella spettrometria di massa

possono tutelare l’oro blu del XXI secolo

Mercoledì 14 Marzo 2012

Organizzato in collaborazione con il Dipartimento di Scienze Farmaceutiche “Pietro Pratesi” dell’Università degli Studi di Milano

pressoDISFARM - Aula Magna C3

Via L. Mangiagalli, 25 - Milano

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3 © 2011 AB SCIEX

Agenda Seminario

ACQUA e LC-MS: come le innovazioni nella spettrometria di massa possono tutelare l’oro blu del XXI secolo

Mercoledì 14 Marzo 2012

Organizzato in collaborazione con il DISFARM dell’Università degli Studi di Milano

9.30 Benvenuto e Introduzione ai lavori Marina Carini-Università degli Studi di Milano9.45 La sinergia fra produttori di strumenti e mondo scientifico Nicola La Monica-AB SCIEX

10.00 Come affrontare le nuove richieste della legislazione sulle acque- Stefano Polesello-IRSA-CNR

10.30 Identificazione di farmaci e droghe d'abuso in acque reflue e di superficie mediante spettrometria di massa Sara Castiglioni-Istituto Mario Negri

11.00 Coffee Break11.30 Dalla preparazione online all’iniezione diretta di campioni di acqua: l’evoluzione dell’LC-MS

Samuele Scurati-AB SCIEX12.00Nuove tecnologie LC-MS, nuove sfide ambientali e nuove politiche dei laboratori in ARPA Lombardia Giulio Sesana-Dipartimento di Brescia – ARPA, Pierluisa Dellavedova, Marco Volante,

Settore Laboratorio – ARPA12.30 Vedere la foresta prima degli alberi ? La sfida di trovare l’inaspettato S.FiorinaABSCIEX

13.00 Buffet14.00 Accreditamento di procedure analitiche basate sull'impiego di LC-MS/MS nel campo

ambientale: problematiche e prospettive future Maurizio Bettinelli C.M.B. – Piacenza14.30 A new on-line solid phase extraction high performance liquid chromatography tandem mass

spectrometry method to study the sun light photodegradation of mono-chloroanilines in river water Fabio Gosetti-Università del Piemonte Orientale "A. Avogadro“

15.15Discussione e conclusione dei lavori

4 © 2011 AB SCIEX

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5 © 2011 AB SCIEX

Who We AreGlobal Leader in Mass Spectrometry

AB SCIEX helps to improve the world we live in by empowering scientists and lab analysts to push the limits in their fields

More than a 20-yearhistory of innovation

and market leadership

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“With AB SCIEX, we can dogreat science”

Michael Siu,York University

“We trust AB SCIEX”Fabiio Garofolo,Algorithme Pharma

“We push the limits of detectionwith AB SCIEX products”

Mark Molloy,APAF

“AB SCIEX has takenthe market”

Tony Purcell,University of Melbourne

Drug Discovery & Development

Clinical Research & Forensic Toxicology

Biomarkers & OMICs

Food Safety & Environmental Analysis

Who OurCustomers Are

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7 © 2011 AB SCIEX

First to integrate a triple quadruple and a linear ion trap on the same platform

Enabling Our Customers’ SuccessAB SCIEX innovation has produced many breakthrough technologies that significantly improve how scientists obtain results

Created time-of-flight/time-of-flight (TOF/TOF) mass spectrometry

Invented liquidchromatography/mass spectrometry (LC/MS

Pioneered mass spectrometry/mass spectrometry (MS/MS)on a triple quadrupole

First to integrate high resolution and accuratemass with high speed and high sensitivity

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Technology PlatformsAB SCIEX provides the most innovative, high performance mass spectrometers in the industry

High Resolution,AccurateMass Platform

Fastest and mostsensitivehigh-resolutionmassspectrometer withaccurate mass

TandemTime-of-FlightSystems

Fastest, most comprehensiveTOF/TOF systems for protein biomarker discovery and imaging

Triple Quadrupoles

AB SCIEX QQQsare distinguishedby the highest sensitivityfor quantitative analysis

Eksigent Chromatography Systems

Innovative LC technologies that extend MS capabilities

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9 © 2011 AB SCIEX

Novita da PITCON – PITCON News:il Nuovo 4500QTrap & 4500 Triple Quad e l’Ekspert UHPLC

Pitcon News !

UHPLC pumps that deliver gradients at the highest back pressures, up to 18,000 psi at flow rates up to5.0 mL/min

The 4500 series is a more robust, faster scanning LC/MS/MS system that offers 10X greater sensitivity and enhanced MRM3 selectivity when dealing with complex sample mixtures. Full scan sensitivity in LIT is 100X more sensitive making it ideal for library searching or screening assays.

10 © 2011 AB SCIEX

Applications and MethodsAB SCIEX is a leader in developing application-specific workflows to enhance the use of its industry-leading mass spectrometers

Chemistry Reagents

Specialized chemistries used to study proteins and compounds by analyzing molecular reactions

Application Software

A broad range of software applicationsto simplify mass spectrometry-based workflows

iMethods

The industry’s only pre-configured, downloadable methods to set parameters for laboratory testing, including food analysis, toxicology and clinical research

iMethod Tests

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11 © 2011 AB SCIEX

World-class Service and Support

TechnicalSolution Center

First line of support for instrument issues

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1,500+ associates worldwide

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New Delhi

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13 © 2011 AB SCIEX

AB Sciex in Italia

Il Team AB Sciex in Italia è cresciuto arricchendosi di nuovi professionisti sia nella Consulenza Commerciale che nel Supporto Scientifico e nell’Assistenza Tecnica

AB Sciex si avvale in Italia inoltre anche di 2 laboratori, uno presso il Bio Industry Park di Ivrea e l’altro presso l’ARPA Friuli a Pordenone per lo Sviluppo di Nuove Metodiche, Dimostrazioni e Corsi e da Gennaio 2012 del nuovo Partner DASP

14 © 2011 AB SCIEX

La Sinergia Tra il Produttore ed il Mondo Scientifico

Because welisten to ourcustomers andadopt theirmission…

Leaderswho listen

We become atrusted partnerand collaborateto developsolutions whereone neverexisted…

TrustedPartner

These cutting-edge solutionsenable ourcustomers topush the limitsin their field.

Pushing theLimits

And pushingthe limitsmeans theycan improvethe world welive in.

Dedicated toImproving Life

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15 © 2011 AB SCIEX

La Sinergia Tra il Produttore ed il Mondo ScientificoEnsuring the Safety of Drinking Water

Helping Reinforce Standards to Protect Public Health

Customer: Langenau GermanWater Company

Challenge: Improve test methodsto better identify contamination in water

Product: TripleTOF 5600 System

Impact: Identify contaminants before they taint drinking water

“With AB SCIEX, we can dogreat science”

Michael Siu,York University

“We trust AB SCIEX”Fabiio Garofolo,Algorithme Pharma

“We push the limits of detectionwith AB SCIEX products”

Mark Molloy,APAF

“AB SCIEX has takenthe market”

Tony Purcell,University of Melbourne

Drug Discovery & Development

Clinical Research & Forensic Toxicology

Biomarkers & OMICs

Food Safety & Environmental Analysis

VOI ed ……AB Sciex

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17 © 2011 AB SCIEX

Grazie !