Darunavir/ritonavir
Transcript of Darunavir/ritonavir
Reactions 1482, p18 - 14 Dec 2013
Darunavir/ritonavir
Depressive syndrome: case reportIn an observational study of 65 HIV-infected patients, aged
40–49 years, 35 patients were switched from double ritonavir-boosted protease inhibitor therapy to darunavir/ritonavireither once or twice daily [dose and route not stated]. One ofthese patients [exact age and sex not stated] stopped darunavir/ritonavir due to the onset of depressive syndrome [duration oftreatment to reaction onset and outcome not stated].
Author comment: "[O]ne patient in the [darunavir/ritonavir] arm stopped treatment due to side effects(depressive syndrome)".Curran A, et al. Efficacy and safety of switching double-boosted proteaseinhibitors to boosted darunavir in HIV-infected patients with virologic suppression.Journal of the International AIDS Society 15 (Suppl. 4): 162-163 abstr. P297, 11Nov 2012. Available from: URL: http://dx.doi.org/10.7448/IAS.15.6.18350 -Spain 803096952
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Reactions 14 Dec 2013 No. 14820114-9954/13/1482-0001/$14.95 Adis © 2013 Springer International Publishing AG. All rights reserved