CURRICULUM VITAE

Prof. Salvatore Cuzzocrea, PhD

Dati personali:Nome: Salvatore

Cognome: Cuzzocrea

Luogo di Nascita: Ginevra (Svizzera)

Data di Nascita: 11 Marzo 1972

Stato Civile: Coniugato

Indirizzi:

Abitazione: Via San Filippo Bianchi n. 19, 98123

Messina.

Telefono: 090 - 710741

Email: salvator@unime. it

Istituto: Istituto di Farmacologia, Facoltà di Medicina e Chirurgia

Università di Messina, Torre Biologica Policlinico Universitario 98100

Messina.

Telefono: 090 - 2213644

Fax: 090 - 2213300

TITOLI DI STUDIO:

1990: Diploma di maturità classica (46/60).

1995: Laurea in Farmacia, l'Università di Messina, (110/110 e Lode).

1995: Abilitazione alla professione di Farmacista (270/350).

1999: Dottore di ricerca in “Medicina Sperimentale” Università di Messina.

1999-2002: Ricercatore in Farmacologia, Facoltá di Medicina e Chirurgia Università di Messina.

2001- ad oggi: Honorary Lecturer in Pharmacology at the Department of Experimental Medicine

and Nephrology" at The William Harvey at The St. Bartholomew’s and Royal London School of

Medicine and Dentistry,

2002- ad oggi: Professore Associato in Farmacologia, Facoltá di Medicina e Chirurgia Università di

Messina.

ESPERIENZE DI RICERCA

1993-1994: Allievo interno in Farmacologia, Direttore Prof. Anna De pasquale, Facoltà di

Farmacia Università di Messina.

1994-1995: Allievo interno presso il Dipartimento di Farmacologia Sperimentale, Tutore Prof.

Massimo Di Rosa Università “Federico II” di Napoli .

1995-1999: Dottorando di ricerca in “Medicina Sperimentale” (XI ciclo) presso l'Istituto di

Farmacologia (Coordinatore Prof. Achille P. Caputi) Facoltà di Medicina e Chirurgia, Università

di Messina.

ESPERIENZE DI RICERCA IN LABORATORI ESTERNI A QUELLO DEL

DOTTORATO

Novembre1995-Maggio 1996: presso l'Istituto di Farmacologia e Tossicologia, Seconda

Università di Napoli, Direttore Prof. Francesco Rossi Tutore Prof. Achille P. Caputi.

Giugno 1996-Giugno 1997: presso l'Unità di Terapia Intensiva, Children's Hospital Medical

Center, Cincinnati, USA Direttore Prof. Andrew L. Salzman , Tutore Prof. Achille P. Caputi.

Aprile 1998-Settembre 1998: presso il Department of Biochemical Pharmacology at The

William Harvey at The St. Bartholomew’s and Royal London School of Medicine and Dentistry,

Direttore Prof. RJ. Flower, Tutore Prof. Achille P. Caputi.

ATTIVITA’ DIDATTICA

1996-1999: Docente di “Storia della Farmacia” Corso di perfezionamento in “Storia della

Medicina” Università di Messina.

1999- 2001: Docente di “Farmacologia” Diploma Universitario per Ostetriche. Facoltà di

Medicina e Chirurgia, Università di Messina.

1999- 2001: Docente di “Farmacologia” Diploma Universitario per infermieri professionali.

Facoltà di Medicina e Chirurgia, Università di Messina.

1999- ad oggi: Docente di “Farmacologia” Corso di laurea in Odontoiatria. Facoltà di Medicina

e Chirurgia, Università di Messina.

2001-ad oggi: Docente nel “Dottorato di Ricerca in Medicina Sperimentale” Facoltà di Medicina

e Chirurgia, Università di Messina.

2001- ad oggi: Docente di “Immunofarmacologia” Scuola di Specializzazione in Farmacologia,

Facoltà di Medicina e Chirurgia, Università di Messina.

2001- ad oggi: Docente di “Farmacologia” Scuola di Specializzazione in Medicina dello Sport,

Facoltà di Medicina e Chirurgia, Università di Messina.

2002- ad oggi: Docente di “Farmacologia” Scuola di Specializzazione in Reumatologia, Facoltà

di Medicina e Chirurgia, Università di Messina.

2002- ad oggi: Docente Incaricato di “Farmacologia” Corso di laurea in Ostetricia. Facoltà di

Medicina e Chirurgia, Università di Messina.

2002- ad oggi: Docente Incaricato di “Farmacologia” Corso di laurea in infermieri professionali.

Facoltà di Medicina e Chirurgia, Università di Messina.

2004- ad oggi: Docente di “Tossicologia Sperimentale” Scuola di Specializzazione in

Tossicologia Medica, Facoltà di Medicina e Chirurgia, Università di Messina.

2005- ad oggi:: Docente nel “Dottorato di ricerca in Biotecnologie Farmacologiche e

Farmacologia Clinica” presso Dipartimento di Medicina Clinica e Sperimentale (Coordinatore

Prof. Carlo Riccardi) Facoltà di Medicina e Chirurgia, Università di Perugia.

2007- ad oggi: Docente di “Farmacologia” Corso di laurea Scienze biologiche Farmacologia

molecolare, cellulare e sperimentale Curriculum Biosanitario, Facoltà di Scienze Mm.FF.NN ,

Università di Messina.

2007- ad oggi: Docente di “Farmacologia” Corso di laurea Scienze biologiche Farmacologia

Curriculum: Biologia degli alimenti e della Nutrizione Facoltà di Scienze Mm.FF.NN ,

Università di Messina.

PREMI DI STUDIO:

1995: Premio Gionco (Verona 13-16 Maggio 1996)

1997: Premio di Studio della “Società Italiana di Farmacologia” , Roma.

1998: Vincitore del “Travel Grant Awards” 53th Work-shop: Melatonin and its Analogues: from

Molecular Biology to the Clinical Application.

1998: Vincitore del “Travel Grant Awards” The 6th Joint meeting of the Italian, Hungarian and

Polish Pharmacological Society.

1998: Premio di Studio del “Centro Nazionale delle Ricerche” Roma, per soggiorno all'estero

presso Department of Biochemical Pharmacology at The William Harvey at The St.

Bartholomew’s and Royal London School of Medicine and Dentistry, Direttore Prof. RJ. Flower.

1998: Vincitore del Premio "Young Investigator Award" (prima posizione) al 8st Congress of the

European Shock Society, La Hulpe, Belgio.

1998: Vincitore del Premio “Linus Pauling Award Biomedicina 98” Special Mention in

Farmacologia al congresso di Biomedicina ’98 Meeting on Molecular Medicine Firenze, Italia.

1999: Vincitore del “Travel Grant Awards” Joint meeting of the French and Italian Societies of

Pharmacology, Nantes, Francia.

1999: Vincitore del “Travel Grant Awards” XXIX Congresso Nazionale dell Società Italiana di

Farmacologia, Firenze, Italia.

1999: Vincitore del “Travel Grant Awards” 2nd European Congress of Pharmacology, Budapest,

Ungheria.

1999: Vincitore del “Pharmalink/ European Shock Society Reasearch Awards” 7th Vienna Shock

Forum, Vienna Austria.

2000: Vincitore del Premio “Miglior Lavoro in Tossicologia del 1999” Società Italiana di

Tossicologia, XII Congresso Nazionale di Tossicologia, Bologna, Italia,

2000: Vincitore del “Travel Grant Awards” BPS/SIF, Birmingham, Inghilterra.

2008: Vincitore premio Galeno 2008.

ASSOCIAZIONI SCIENTIFICHE:

1997: Società Italiana di Farmacologia

1997: Società Italiana di Tossicologia

1997: American Shock society

1997: Associazione Europea per la Ricerca Biomedica

1998: European Shock Society

1999: British Pharmacological Society

1999: International Endotoxin Society

1999: Society of Leukocyte Biology

2000: Societá Italiana di Ricerche Cardiovascolari

2000: Molecular Medicine Society

2006: European Society for Free Radical Research

2007: Societá Italiana di Neuroscienze

Referee per gli elencati Giornali Scientifici:

European Journal of Pharmacology - Life Science - J. Pineal Research - Inflammation Research -British J. Pharmacology - Cardiovascular Research - Am J Resp. Crit Care – Gut – Shock - Physiology and Behavior - Archives of Biochemistry and Biophysics - Pharmacological Research – Digestive Disease of Science- Current Medicinal Chemistry Anti-Infective & Anti-Allergy Agents - American J. Pathology - European Respiratory Journal - Intensive Care Medicine - Medical Science Monitoring- Journal of Hepatology - Cytokine – Critical Care Medicine – Journal of Autonomic Nervous system – Brain Research – Circulation – Gastroenterology - Blood Coagulation & Fibrinolysis – Endocrinology-Calcified Tissue International. – J. Surgical Research - Journal of Pharmacology and Experimental Therapeutics – Am. J Physiol Gast. and Liver - Journal of Neurochemistry- Anesthesia & Analgesia - Experimental Physiology - Pediatric Research- Rheumatology – Carcinogenesis - Neuroscience Letters - Free Radical Research- Journal of Dental Research - Pharmacology, Biochemistry and Behavior – European Journal of Histochemistry - Future Rheumatology- Chinese Journal of Physiology- Redox Report-Neurochemistry International- Chemico-Biological Interactions - BMC Pharmacology – Neuropharmacology - International Immunopharmacology - Spinal Cord - Cell Proliferation - Histology and Histopathology - BMC Complementary and Alternative Medicine - Tohoku J. Exp. Med – Immunobiology - Cell. Mol. Biol. Lett- Neurochemical Research - Immunology Letters - Archives of Orthopaedic and Trauma Surgery - Journal of Cardiovascular Pharmacology – Future Medicine – Immunobiology – Journal of Cellular and Molecular Medicine - Current Medicinal Chemistry – Central Nervous System Agents - BMC Neuroscience - Journal Methods and Findings in Experimental and Clinical Pharmacology - Regulatory Peptides. .

INVITED LECTURE:

1998: “Melatonin and Inflammation” Department of Cellular and Structural Biology. The University of Texas at San Antonio Texas USA.1998: “Role of interleukin-6 in inflammation” The William Harvey Research Institute, St. Bartholomew’s and The Royal London School of Medicine and Dentistry, Charterhouse Square, London, United Kingdom.1998: “Free Radical and shock” Ludwig-Boltzmann-Institut for Experimental and Clinical Traumatology, Vienna, Austria. 1999: “SOD mimetic in Inflammation and Shock” Metaphore Pharmaceuticals, St Louis, USA.1999: “Role of peroxynitrite and Poly (ADP-Ribose) synthetase (PARS) in inflammation and Shock. St. Louis University, St Louis, USA.1999: “Endogenous and exogenous melatonin” International Symposium: Receptor and non-receptor mediated action of Melatonin”, Hong Kong, Cina.2000: “Antioxidant Properties of Endogenous and exogenous melatonin” The second International Conference on Basic Science and Advanced Technology, Assiut, Egitto.2002: “Role of Free Radicals in inflammation, shock and ischemia and reperfusion” Faculty of Pharmacy, University of Salerno, Salerno, Italy.2002: “Beneficial Effects of new SOD mimetics in acute and chronic inflammation” Faculty of Pharmacy, University of Salerno, Salerno, Italy.2003: “Prospectives of antioxidant therapy in the critically ill” Sektion Anasthesiologische Pathophysiologie und Verfahrensentwicklung, Universitatsklinik fur Anasthesiologie, Universitat Ulm, Ulm, Germany.2003: “Role of Free Radicals in inflammation, shock and ischemia and reperfusion” International Agency for Research on Cancer (IARC), Lyon, France.2003: “Role of Nitric Oxide in acute and chronic inflammmation” Bio-Medical Applications of Biotechnology, Havana, Cuba.2004: “Role of ROS in inflammation, shock and ischemia and reperfusion” 2nd International Congress of Pharmacology and Therapeutics, Havana, Cuba.2004: “Pharmacological action of PPAR-γ ligands in acute and chronic inflammation” 2nd

International Congress of Pharmacology and Therapeutics, Havana, Cuba.2004: “Role of ROS in inflammation, shock and ischemia and reperfusion” Faculty of Pharmacy, University of Calabria, Catanzaro, Italy.2005: “Peroxisome Proliferator-Activated Receptors (PPARs) in Autoimmune Disease” School of Medicine, University of Perugia, Perugia, Italy.2007: “Role of Glucocorticoid-Induced TNFR Related Gene (GITR) in the regulation of Inflammatory Response during Acute and Chronic Inflammation” The William Harvey Research Institute, St. Bartholomew’s and The Royal London School of Medicine and Dentistry, Charterhouse Square, London, United Kingdom.

LAVORI IN ESTENSO SU RIVISTE INTERNAZIONALI CON COMITATO DI

REFEREE

1. EFFECT OF PD98059, A SELECTIVE MAPK3/MAPK1 INHIBITOR, ON ACUTE LUNG INJURY IN MICE. Di Paola R, Crisafulli C, Mazzon E, Genovese T, Paterniti I, Bramanti P, Cuzzocrea S. Int J Immunopathol Pharmacol. 2009 Oct-Dec;22(4):937-50. I.F. 2,157 I.F. 2,793

2. LIVER X RECEPTOR AGONIST TREATMENT REDUCED SPLANCHNIC ISCHEMIA AND REPERFUSION INJURY Crisafulli C, Di Paola R, Mazzon E, Paterniti I, Galuppo M, Genovese T, Bramanti P, Cappellani A, Cuzzocrea S.. J Leukoc Biol. 2010 Feb;87(2):309-21. I.F. 4,605

3. ESTROGEN RECEPTOR-ALPHA AS A DRUG TARGET CANDIDATE FOR PREVENTING LUNG INFLAMMATION. Vegeto E, Cuzzocrea S, Crisafulli C, Mazzon E, Sala A, Krust A, Maggi A. Endocrinology. 2010 Jan;151(1):174-84. I.F. 4,945

4. SELECTIVE N-ACYLETHANOLAMINE-HYDROLYZING ACID AMIDASE INHIBITION REVEALS A KEY ROLE FOR ENDOGENOUS PALMITOYLETHANOLAMIDE IN INFLAMMATION. Solorzano C, Zhu C, Battista N, Astarita G, Lodola A, Rivara S, Mor M, Russo R, Maccarrone M, Antonietti F, Duranti A, Tontini A, Cuzzocrea S, Tarzia G, Piomelli D. Proc Natl Acad Sci U S A. 2009 Dec 8;106(49):20966-71. I.F. 9,380

5. PROTECTIVE EFFECT OF VERBASCOSIDE IN ACTIVATED C6 GLIOMA CELLS: POSSIBLE MOLECULAR MECHANISMS Esposito E, Dal Toso R, Pressi G, Bramanti P, Meli R, Cuzzocrea S.. Naunyn Schmiedebergs Arch Pharmacol. 2010 Jan;381(1):93-105. Epub 2009 Nov 11. I.F. 2,161

6. ROLE FOR ENDOTHELIAL NITRIC OXIDE SYNTHASE IN NITRITE-INDUCED PROTECTION AGAINST RENAL ISCHEMIA-REPERFUSION INJURY IN MICE.Milsom AB, Patel NS, Mazzon E, Tripatara P, Storey A, Mota-Filipe H, Sepodes B, Webb AJ, Cuzzocrea S, Hobbs AJ, Thiemermann C, Ahluwalia A. Nitric Oxide. 2010 Feb 15;22(2):141-148. I.F. 2,650

7. LIVER X RECEPTOR AGONIST TREATMENT REGULATES INFLAMMATORY RESPONSE AFTER SPINAL CORD TRAUMA Paterniti I, Genovese T, Mazzon E, Crisafulli C, Di Paola R, Galuppo M, Bramanti P, Cuzzocrea S.. J Neurochem. 2010 Feb;112(3):611-24. Epub 2009 Nov 4. I.F. 4,5

8. PALMITOYLETHANOLAMIDE MODULATES PENTOBARBITAL-EVOKED HYPNOTIC EFFECT IN MICE INVOLVEMENT OF ALLOPREGNANOLONE BIOSYNTHESIS.

Sasso O, La Rana G, Vitiello S, Russo R, D'Agostino G, Iacono A, Russo E, Citraro R, Cuzzocrea S, Piazza PV, De Sarro G, Meli R, Calignano A. Eur Neuropsychopharmacol. 2010 Mar;20(3):195-206. I.F. 3,661

9. PD98059, A SPECIFIC MAP KINASE INHIBITOR, ATTENUATES MULTIPLE ORGAN DYSFUNCTION SYNDROME/FAILURE (MODS) INDUCED BY ZYMOSAN IN MICE Di Paola R, Galuppo M, Mazzon E, Paterniti I, Bramanti P, Cuzzocrea S.. Pharmacol Res. 2010 Feb;61(2):175-87. I.F. 3,287

10. DEXAMETHASONE AMELIORATES RENAL ISCHEMIA-REPERFUSION INJURY. Kumar S, Allen DA, Kieswich JE, Patel NS, Harwood S, Mazzon E, Cuzzocrea S, Raftery MJ, Thiemermann C, Yaqoob MM. J Am Soc Nephrol. 2009 Nov;20(11):2412-25. Epub 2009 Sep 24. I.F. 7,505

11. PPAR-ALPHA CONTRIBUTES TO THE ANTI-INFLAMMATORY ACTIVITY OF 17BETA-ESTRADIOL Crisafulli C, Bruscoli S, Esposito E, Mazzon E, Di Paola R, Genovese T, Bramanti P, Migliorati G, Cuzzocrea S.. J Pharmacol Exp Ther. 2009 Dec;331(3):796-807. I.F. 4,309

12. TNF-ALPHA AS A THERAPEUTIC TARGET IN INFLAMMATORYDISEASES, ISCHEMIA-REPERFUSION INJURY AND TRAUMA Esposito E, Cuzzocrea S.. Curr Med Chem. 2009;16(24):3152-67. Review. I.F. 4,823

13. THALIDOMIDE SUPPRESSES SCLEROSING ENCAPSULATING PERITONITIS IN A RAT EXPERIMENTAL MODEL Mondello S, Mazzon E, Di Paola R, Crisafulli C, Mondello P, Buemi M, Aloisi C, Cuzzocrea S.. Shock. 2009 Sep;32(3):332-9. I.F. 3,394

14. GREEN TEA POLYPHENOLS AMELIORATE PANCREATIC INJURY IN CERULEIN-INDUCED MURINE ACUTE PANCREATITIS. Babu BI, Malleo G, Genovese T, Mazzon E, Di Paola R, Crisafulli C, Caminiti R, Siriwardena AK, Cuzzocrea S. Pancreas. 2009 Nov;38(8):954-67. I.F. 2,708

15. SPINAL CERAMIDE AND NEURONAL APOPTOSIS IN MORPHINE ANTINOCICEPTIVE TOLERANCE. Bryant L, Doyle T, Chen Z, Cuzzocrea S, Masini E, Vinci MC, Esposito E, Mazzon E, Petrusca DN, Petrache I, Salvemini D. Neurosci Lett. 2009 Sep 29;463(1):49-53. I.F. 2,200

16.ROLE OF NITROSO RADICALS AS DRUG TARGETS IN CIRCULATORY SHOCK. BR J PHARMACOL.Esposito E, Cuzzocrea S. 2009 Jun;157(4):494-508. Review. I.F. 4,902

17. SUPRASPINAL INACTIVATION OF MITOCHONDRIAL SUPEROXIDE DISMUTASE IS A SOURCE OF PEROXYNITRITE IN THE DEVELOPMENT OF MORPHINE ANTINOCICEPTIVE TOLERANCE Doyle T, Bryant L, Batinic-Haberle I, Little J, Cuzzocrea S, Masini E, Spasojevic I, Salvemini D.. Neuroscience. 2009 Dec 1;164(2):702-10. I.F. 3,556

18. ROLE OF PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR-ALPHA IN ILEUM TIGHT JUNCTION ALTERATION IN MOUSE MODEL OF RESTRAINT STRESS. Mazzon E, Crisafulli C, Galuppo M, Cuzzocrea S. Am J Physiol Gastrointest Liver Physiol. 2009 Sep;297(3):G488-505. I.F. 3,587

19. IBUPROFEN-ARGININE GENERATES NITRIC OXIDE AND HAS ENHANCED ANTI-INFLAMMATORY EFFECTS. De Palma C, Di Paola R, Perrotta C, Mazzon E, Cattaneo D, Trabucchi E, Cuzzocrea S, Clementi E. Pharmacol Res. 2009 Oct;60(4):221-8. I.F. 2,604

20.THE ROLE OF ENDOGENOUS AND EXOGENOUS LIGANDS FOR THE PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR ALPHA (PPAR-ALPHA) IN THE REGULATION OF INFLAMMATION IN MACROPHAGES. Crisafulli C, Cuzzocrea S. Shock. 2009 Jul;32(1):62-73. I.F.3,394

21.THE P2Y-LIKE RECEPTOR GPR17 AS A SENSOR OF DAMAGE AND A NEW POTENTIAL TARGET IN SPINAL CORD INJURY Ceruti S, Villa G, Genovese T, Mazzon E, Longhi R, Rosa P, Bramanti P, Cuzzocrea S, Abbracchio MP.. Brain. 2009 Aug;132(Pt 8):2206-18. I.F. 9,603

22. HETEROGENEOUS EXPRESSION OF CYCLOOXYGENASE-2 AND INDUCIBLE NITRIC OXIDE SYNTHASE WITHIN COLORECTAL TUMORS: CORRELATION WITH TUMOR ANGIOGENESIS.Cianchi F, Cuzzocrea S, Vinci MC, Messerini L, Comin CE, Navarra G, Perigli G, Centorrino T, Marzocco S, Lenzi E, Battisti N, Trallori G, Masini E. Dig Liver Dis.2010 Jan;42(1):20-7. I.F. 1,98

23. PROTECTIVE EFFECT OF MELATONIN AGAINST THE INFLAMMATORY RESPONSE ELICITED BY CRUDE VENOM FROM ISOLATED NEMATOCYSTS OF PELAGIA NOCTILUCA (CNIDARIA, SCYPHOZOA). Marino A, Di Paola R, Crisafulli C, Mazzon E, Morabito R, Paterniti I, Galuppo M, Genovese T, La Spada G, Cuzzocrea S. J Pineal Res. 2009 Aug;47(1):56-69. I.F. 5,056

24.EFFECTS OF GENETIC AND PHARMACOLOGICAL INHIBITION OF TNF-ALPHA IN THE REGULATION OF INFLAMMATION IN MACROPHAGES Crisafulli C, Galuppo M, Cuzzocrea S. Pharmacol Res. 2009 Oct;60(4):332-40. I.F.3,287

25. EFFECTS OF A METALLOPORPHYRINIC PEROXYNITRITE DECOMPOSITION CATALYST, WW-85, IN A MOUSE MODEL OF SPINAL CORD INJURY

Genovese T, Mazzon E, Esposito E, Di Paola R, Murthy K, Neville L, Bramanti P, Cuzzocrea S.. Free Radic Res. 2009 Jul;43(7):631-45. I.F. 2,826

26. PPAR-ALPHA MODULATE THE ANTI-INFLAMMATORY EFFECT OF GLUCOCORTICOIDS IN THE SECONDARY DAMAGE IN EXPERIMENTAL SPINAL CORD TRAUMA. Genovese T, Esposito E, Mazzon E, Crisafulli C, Paterniti I, Di Paola R, Galuppo M, Bramanti P, Cuzzocrea S. Pharmacol Res. 2009 May;59(5):338-50. Epub 2009 Feb 13. I.F.3,287

27. CENTRAL ADMINISTRATION OF PALMITOYLETHANOLAMIDE REDUCES HYPERALGESIA IN MICE VIA INHIBITION OF NF-KAPPAB NUCLEAR SIGNALLING IN DORSAL ROOT GANGLIA.D'Agostino G, La Rana G, Russo R, Sasso O, Iacono A, Esposito E, Mattace Raso G, Cuzzocrea S, Loverme J, Piomelli D, Meli R, Calignano A. Eur J Pharmacol. 2009 Jun 24;613(1-3):54-9. I.F.2,787

28. MATERNAL ADAPTATION IN PREGNANT HYPERTENSIVE RATS: IMPROVEMENT OF VASCULAR AND INFLAMMATORY VARIABLES AND OXIDATIVE DAMAGE IN THE KIDNEY.Iacono A, Bianco G, Mattace Raso G, Esposito E, d'Emmanuele di Villa Bianca R, Sorrentino R, Cuzzocrea S, Calignano A, Autore G, Meli R. Am J Hypertens. 2009 Jul;22(7):777-83. I.F.3,122

29. INVOLVEMENT OF LEUKOTRIENE PATHWAY IN THE PATHOGENESIS OF ISCHEMIA-REPERFUSION INJURY AND SEPTIC AND NON-SEPTIC SHOCK Rossi A, Cuzzocrea S, Sautebin L.. Curr Vasc Pharmacol. 2009 Apr;7(2):185-97. Review. I.F. 4,12

30. TREATMENT WITH GREEN TEA EXTRACT ATTENUATES SECONDARY INFLAMMATORY RESPONSE IN AN EXPERIMENTAL MODEL OF SPINAL CORD TRAUMA. Paterniti I, Genovese T, Crisafulli C, Mazzon E, Di Paola R, Galuppo M, Bramanti P, Cuzzocrea S. Naunyn Schmiedebergs Arch Pharmacol. 2009 Aug;380(2):179-92. I.F.2,161

31. PROBIOTICS REDUCE THE INFLAMMATORY RESPONSE INDUCED BY A HIGH-FAT DIET IN THE LIVER OF YOUNG RATS Esposito E, Iacono A, Bianco G, Autore G, Cuzzocrea S, Vajro P, Canani RB, Calignano A, Raso GM, Meli R.. J Nutr. 2009 May;139(5):905-11. I.F. 3,689

32. THE SELECTIVE ADENOSINE A2A RECEPTOR AGONIST CGS 21680 REDUCES JNK MAPK ACTIVATION IN OLIGODENDROCYTES IN INJURED SPINAL CORD. Genovese T, Melani A, Esposito E, Mazzon E, Di Paola R, Bramanti P, Pedata F, Cuzzocrea S. Shock. 2009 Dec;32(6):578-85. I.F.3,394

33. PROTECTIVE EFFECTS OF A COUMARIN DERIVATIVE IN DIABETIC RATS.Bucolo C, Ward KW, Mazzon E, Cuzzocrea S, Drago F. Invest Ophthalmol Vis Sci. 2009 Aug;50(8):3846-52. I.F. 3,583

34. SUPEROXIDE, NO, PEROXYNITRITE AND PARP IN CIRCULATORY SHOCK AND INFLAMMATION.Esposito E, Cuzzocrea S. Front Biosci. 2009 Jan 1;14:263-96. I.F.3,308

35. EFFECTS OF VERBASCOSIDE BIOTECHNOLOGICALLY PRODUCED BY SYRINGA VULGARIS PLANT CELL CULTURES IN A RODENT MODEL OF COLITIS. Mazzon E, Esposito E, Di Paola R, Riccardi L, Caminiti R, Dal Toso R, Pressi G, Cuzzocrea S. Naunyn Schmiedebergs Arch Pharmacol. 2009 Jul;380(1):79-94. I.F.2,161

36. ABSENCE OF ENDOGENOUS INTERLEUKIN-10 ENHANCES SECONDARY INFLAMMATORY PROCESS AFTER SPINAL CORD COMPRESSION INJURY IN MICE.Genovese T, Esposito E, Mazzon E, Di Paola R, Caminiti R, Bramanti P, Cappelani A, Cuzzocrea S. J Neurochem. 2009 Mar;108(6):1360-72. I.F.4,5

37.COMPARATIVE THERAPEUTIC EFFECTS OF METFORMIN AND VITAMIN E IN A MODEL OF NON-ALCOHOLIC STEATOHEPATITIS IN THE YOUNG RAT. Raso GM, Esposito E, Iacono A, Pacilio M, Cuzzocrea S, Canani RB, Calignano A, Meli R. Eur J Pharmacol. 2009 Feb 14;604(1-3):125-31. I.F. 2,787

38. MELATONIN REDUCES STRESS-ACTIVATED/MITOGEN-ACTIVATED PROTEIN KINASES IN SPINAL CORD INJURY Esposito E, Genovese T, Caminiti R, Bramanti P, Meli R, Cuzzocrea S.. J Pineal Res. 2009 Jan;46(1):79-86. I.F. 5,056

39. ERYTHROPOIETIN SUPPRESSES PERITONEAL FIBROSIS IN RAT EXPERIMENTAL MODEL Mondello S, Mazzon E, Di Paola R, Crisafulli C, Italiano D, Buemi M, Aloisi C, Cuzzocrea S.. Eur J Pharmacol. 2009 Feb 14;604(1-3):138-49. I.F. 2,787

40. TEUPOLIOSIDE, A PHENYLPROPANOID GLYCOSIDES OF AJUGA REPTANS, BIOTECHNOLOGICALLY PRODUCED BY IRBN22 PLANT CELL LINE, EXERTS BENEFICIAL EFFECTS ON A RODENT MODEL OF COLITIS. Di Paola R, Esposito E, Mazzon E, Riccardi L, Caminiti R, Dal Toso R, Pressi G, Cuzzocrea S. Biochem Pharmacol. 2009 Mar 1;77(5):845-57. I.F. 4,838

41.16,16-DIMETHYL PROSTAGLANDIN E2 EFFICACY ON PREVENTION AND PROTECTION FROM BLEOMYCIN-INDUCED LUNG INJURY AND FIBROSIS. Failla M, Genovese T, Mazzon E, Fruciano M, Fagone E, Gili E, Barera A, La Rosa C, Conte E, Crimi N, Cuzzocrea S, Vancheri C. Am J Respir Cell Mol Biol. 2009 Jul;41(1):50-8. Epub 2008 Dec 4. I.F. 4,477

42. MYRTUCOMMULONE FROM MYRTUS COMMUNIS EXHIBITS POTENT ANTI-INFLAMMATORY EFFECTIVENESS IN VIVO. Rossi A, Di Paola R, Mazzon E, Genovese T, Caminiti R, Bramanti P, Pergola C, Koeberle A, Werz O, Sautebin L, Cuzzocrea S. J Pharmacol Exp Ther. 2009 Apr;329(1):76-86. Epub 2008 Dec 4. I.F.4,309

43. ETHYL PYRUVATE REDUCES THE DEVELOPMENT OF ZYMOSAN-INDUCED GENERALIZED INFLAMMATION IN MICE. Di Paola R, Mazzon E, Genovese T, Crisafulli C, Bramanti P, Caminiti R, Esposito E, Fink MP, Cuzzocrea S. Crit Care Med. 2009 Jan;37(1):270-82. I.F. 6,594

44.SPINAL CERAMIDE MODULATES THE DEVELOPMENT OF MORPHINE ANTINOCICEPTIVE TOLERANCE VIA PEROXYNITRITE-MEDIATED NITROXIDATIVE STRESS AND NEUROIMMUNE ACTIVATION Ndengele MM, Cuzzocrea S, Masini E, Vinci MC, Esposito E, Muscoli C, Petrusca DN, Mollace V, Mazzon E, Li D, Petrache I, Matuschak GM, Salvemini D.. J Pharmacol Exp Ther. 2009 Apr;329(1):64-75. Epub 2008 Nov 25. I.F.4,309

45.PURE MNTBAP SELECTIVELY SCAVENGES PEROXYNITRITE OVER SUPEROXIDE: COMPARISON OF PURE AND COMMERCIAL MNTBAP SAMPLES TO MNTE-2-PYP IN TWO MODELS OF OXIDATIVE STRESS INJURY, AN SOD-SPECIFIC ESCHERICHIA COLI MODEL AND CARRAGEENAN-INDUCED PLEURISY.Batinić-Haberle I, Cuzzocrea S, Rebouças JS, Ferrer-Sueta G, Mazzon E, Di Paola R, Radi R, Spasojević I, Benov L, Salvemini D. Free Radic Biol Med. 2009 Jan 15;46(2):192-201. I.F.5,399

46. PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR-ALPHA CONTRIBUTES TO THE RESOLUTION OF INFLAMMATION AFTER RENAL ISCHEMIA/REPERFUSION INJURY.Patel NS, di Paola R, Mazzon E, Britti D, Thiemermann C, Cuzzocrea S. J Pharmacol Exp Ther. 2009 Feb;328(2):635-43. I.F. 4,309

47. GLUCOCORTICOID-INDUCED LEUCINE ZIPPER IS PROTECTIVE IN TH1-MEDIATED MODELS OF COLITIS Cannarile L, Cuzzocrea S, Santucci L, Agostini M, Mazzon E, Esposito E, Muià C, Coppo M, Di Paola R, Riccardi C.. Gastroenterology. 2009 Feb;136(2):530-41. I.F.12,591

48. LIPOPHILICITY IS A CRITICAL PARAMETER THAT DOMINATES THE EFFICACY OF METALLOPORPHYRINS IN BLOCKING THE DEVELOPMENT OF MORPHINE ANTINOCICEPTIVE TOLERANCE THROUGH PEROXYNITRITE-MEDIATED PATHWAYS Batinić-Haberle I, Ndengele MM, Cuzzocrea S, Rebouças JS, Spasojević I, Salvemini D.. Free Radic Biol Med. 2009 Jan 15;46(2):212-9. Epub 2008 Oct 17. I.F. 5,399

49. PROTECTIVE EFFECTS OF GLYCYRRHIZIN IN A GUT HYPOXIA (ISCHEMIA)-REOXYGENATION (REPERFUSION) MODEL. Di Paola R, Menegazzi M, Mazzon E, Genovese T, Crisafulli C, Dal Bosco M, Zou Z, Suzuki H, Cuzzocrea S. Intensive Care Med. 2009 Apr;35(4):687-97. I.F.5,055

50. BENEFICIAL EFFECTS OF ETHYL PYRUVATE IN A MOUSE MODEL OF SPINAL CORD INJURY.Genovese T, Esposito E, Mazzon E, Di Paola R, Meli R, Caminiti R, Bramanti P, Fink MP, Cuzzocrea S. Shock. 2009 Aug;32(2):217-27. I.F.3,394

51. INHIBITION OF CERAMIDE BIOSYNTHESIS AMELIORATES PATHOLOGICAL CONSEQUENCES OF SPINAL CORD INJURY Cuzzocrea S, Deigner HP, Genovese T, Mazzon E, Esposito E, Crisafulli C, Di Paola R, Bramanti P, Matuschak G, Salvemini D.. Shock. 2009 Jun;31(6):634-44. I.F.3,394

52. EFFECTS OF THE IMMUNOMODULATOR, VGX-1027, IN ENDOTOXIN-INDUCED UVEITIS IN LEWIS RATS Mangano K, Sardesai NY, Quattrocchi C, Mazzon E, Cuzzocrea S, Bendtzen K, Meroni PL, Kim JJ, Nicoletti F.. Br J Pharmacol. 2008 Nov;155(5):722-30 I.F.4,902

53. PREDICTIVITY AND SENSITIVITY OF ANIMAL MODELS OF ARTHRITIS. Di Paola R, Cuzzocrea S. Autoimmun Rev. 2008 Oct;8(1):73-5. Epub 2008 Aug 15. Review. I.F.5,371

54. PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR-ALPHA MODULATES THE ANTI-INFLAMMATORY EFFECT OF GLUCOCORTICOIDS IN A MODEL OF INFLAMMATORY BOWEL DISEASE IN MICE.Riccardi L, Mazzon E, Bruscoli S, Esposito E, Crisafulli C, Di Paola R, Caminiti R, Riccardi C, Cuzzocrea S. Shock. 2009 Mar;31(3):308-16 I.F.3,394

55. GLYCYRRHIZIN REDUCES SECONDARY INFLAMMATORY PROCESS AFTER SPINAL CORD COMPRESSION INJURY IN MICE Genovese T, Menegazzi M, Mazzon E, Crisafulli C, Di Paola R, Dal Bosco M, Zou Z, Suzuki H, Cuzzocrea S.. Shock. 2009 Apr;31(4):367-75. I.F.3,394

56. FUMONISIN B1 REDUCES THE DEVELOPMENT OF MULTIPLE ORGAN FAILURE INDUCED BY ZYMOSAN IN MICE. Cuzzocrea S, Genovese T, Mazzon E, Esposito E, Crisafulli C, Di Paola R, Bramanti P, Salvemini D. Shock. 2009 Feb;31(2):170-7. I.F.3,394

57. INFLIXIMAB AND ETANERCEPT ARE EQUALLY EFFECTIVE IN REDUCING ENTEROCYTE APOPTOSIS IN EXPERIMENTAL COLITIS Fries W, Muja C, Crisafulli C, Costantino G, Longo G, Cuzzocrea S, Mazzon E. . Int J Med Sci. 2008 Jul 3;5(4):169-80. I.F.

58. ANTI-APOPTOTIC AND ANTI-INFLAMMATORY EFFECTS OF HYDROGEN SULFIDE IN A RAT MODEL OF REGIONAL MYOCARDIAL I/R. Sivarajah A, Collino M, Yasin M, Benetti E, Gallicchio M, Mazzon E, Cuzzocrea S, Fantozzi R, Thiemermann C. Shock. 2009 Mar;31(3):267-74. I.F.3,394

59. EFFECT OF CYCLOPENTANONE PROSTAGLANDIN 15-DEOXY-DELTA12,14PGJ2 ON EARLY FUNCTIONAL RECOVERY FROM EXPERIMENTAL SPINAL CORD INJURY. Genovese T, Esposito E, Mazzon E, Di Paola R, Muià C, Meli R, Bramanti P, Cuzzocrea S. Shock. 2008 Aug;30(2):142-52. I.F.3,394

60. PLANT HISTAMINASE AS AN INVESTIGATIONAL DRUG IN SPLANCHNIC ARTERY OCCLUSION AND REPERFUSION Cuzzocrea S, Masini E.. Expert Opin Investig Drugs. 2008 Aug;17(8):1151-60. Review. I.F.4,058

61. ANTI-INFLAMMATORY AND ANTI-APOPTOTIC EFFECTS OF FUMONISIN B1, AN INHIBITOR OF CERAMIDE SYNTHASE, IN A RODENT MODEL OF SPLANCHNIC ISCHEMIA AND REPERFUSION INJURY Cuzzocrea S, Di Paola R, Genovese T, Mazzon E, Esposito E, Crisafulli C, Bramanti P, Salvemini D.. J Pharmacol Exp Ther. 2008 Oct;327(1):45-57. I.F.4,309

62. GLYCYRRHIZIN ATTENUATES THE DEVELOPMENT OFCARRAGEENAN-INDUCED LUNG INJURY IN MICE Menegazzi M, Di Paola R, Mazzon E, Genovese T, Crisafulli C, Dal Bosco M, ZouZ, Suzuki H, Cuzzocrea S.. Pharmacol Res. 2008 Jul;58(1):22-31. I.F.3,287

63. EFFECT OF TUMOUR NECROSIS FACTOR-ALPHA RECEPTOR 1 GENETIC DELETION ON CARRAGEENAN-INDUCED ACUTE INFLAMMATION: A COMPARISON WITH ETANERCEPT Mazzon E, Esposito E, Di Paola R, Muià C, Crisafulli C, Genovese T, Caminiti R, Meli R, Bramanti P, Cuzzocrea S.. Clin Exp Immunol. 2008 Jul;153(1):136-49. I.F.2,853

64. CYCLOOXYGENASES 1 AND 2 CONTRIBUTE TO PEROXYNITRITE-MEDIATED INFLAMMATORY PAIN HYPERSENSITIVITY Ndengele MM, Cuzzocrea S, Esposito E, Mazzon E, Di Paola R, Matuschak GM, Salvemini D.. FASEB J. 2008 Sep;22(9):3154-64. I.F.7,049

65. STABLE DEPLETION OF POLY (ADP-RIBOSE) POLYMERASE-1 REDUCES IN VIVO MELANOMA GROWTH AND INCREASES CHEMOSENSITIVITY Tentori L, Muzi A, Dorio AS, Bultrini S, Mazzon E, Lacal PM, Shah GM, Zhang J, Navarra P, Nocentini G, Cuzzocrea S, Graziani G.. Eur J Cancer. 2008 Jun;44(9):1302-14. I.F.4,475

66. MATRIX METALLOPROTEINASE-9 AND METALLOPROTEINASE-2 ACTIVITY AND EXPRESSION IS REDUCED BY MELATONIN DURING EXPERIMENTAL COLITIS.Esposito E, Mazzon E, Riccardi L, Caminiti R, Meli R, Cuzzocrea S. J Pineal Res. 2008 Sep;45(2):166-73. I.F.5,056

67. EFFECTS OF PALMITOYLETHANOLAMIDE ON SIGNALING PATHWAYS IMPLICATED IN THE DEVELOPMENT OF SPINAL CORD INJURY. Genovese T, Esposito E, Mazzon E, Di Paola R, Meli R, Bramanti P, Piomelli D, Calignano A, Cuzzocrea S. J Pharmacol Exp Ther. 2008 Jul;326(1):12-23. I.F.4,309.

68. GLUCOCORTICOID-INDUCED TUMORNECROSIS FACTOR RECEPTOR-RELATED (GITR)-FC FUSION PROTEIN INHIBITS GITR TRIGGERING AND PROTECTS FROM THE INFLAMMATORY RESPONSE AFTER SPINAL CORD INJURY Nocentini G, Cuzzocrea S, Genovese T, Bianchini R, Mazzon E, Ronchetti S, Esposito E, Rosanna DP, Bramanti P, Riccardi C.. Mol Pharmacol. 2008 Jun;73(6):1610-21. I.F.4,711.

69. ROLE OF TNF-ALPHA IN ILEUM TIGHT JUNCTION ALTERATION IN MOUSE MODEL OF RESTRAINT STRESS. Mazzon E, Cuzzocrea S. Am J Physiol Gastrointest Liver Physiol. 2008 May;294(5):G1268-80. I.F.3,587.

70. MELATONIN REGULATES MATRIX METALLOPROTEINASES AFTER TRAUMATIC EXPERIMENTAL SPINAL CORD INJURY Esposito E, Genovese T, Caminiti R, Bramanti P, Meli R, Cuzzocrea S.. J Pineal Res. 2008 Sep;45(2):149-56. I.F.5,056

71. ROLE OF FREE RADICALS AND POLY(ADP-RIBOSE)POLYMERASE-1 IN THE DEVELOPMENT OF SPINAL CORD INJURY: NEWPOTENTIAL THERAPEUTIC TARGETS Genovese T, Cuzzocrea S.. Curr Med Chem. 2008;15(5):477-87. Review. I.F.4,823

72. DYNAMICS OF ENTEROCYTE TIGHT JUNCTIONS: EFFECT OF EXPERIMENTAL COLITIS AND TWO DIFFERENT ANTI-TNF TRATEGIES Fries W, Muja C, Crisafulli C, Cuzzocrea S, Mazzon E.. Am J Physiol Gastrointest Liver Physiol. 2008 Apr;294(4):G938-47. I.F.3,587.

73. PROTECTIVE EFFECT OF ARBUTUS UNEDO AQUEOUS EXTRACT IN CARRAGEENAN-INDUCED LUNG INFLAMMATION IN MICE Mariotto S, Esposito E, Di Paola R, Ciampa A, Mazzon E, de Prati AC, Darra E,Vincenzi S, Cucinotta G, Caminiti R, Suzuki H, Cuzzocrea S..Pharmacol Res. 2008 Feb;57(2):110-24. I.F.3,287.

74. EFFECTS OF THALIDOMIDE IN A MOUSE MODEL OF CERULEIN-INDUCED ACUTE PANCREATITIS.Malleo G, Mazzon E, Genovese T, Di Paola R, Muià C, Crisafulli C, SiriwardenaAK, Cuzzocrea S. Shock. 2008 Jan;29(1):89-97. I.F.3,394

75. SPHINGOSYLPHOSPHORYLCHOLINE REDUCES THE ORGAN INJURY/DYSFUNCTION AND INFLAMMATION CAUSED BY ENDOTOXEMIA IN THE RAT. Murch O, Abdelrahman M, Collino M, Gallicchio M, Benetti E, Mazzon E, Fantozzi R, Cuzzocrea S, Thiemermann C. Crit Care Med. 2008 Feb;36(2):550-9. I.F.6,594

76. EFFECT OF THALIDOMIDE ON SIGNAL TRANSDUCTION PATHWAYS AND SECONDARY DAMAGE IN EXPERIMENTAL SPINAL CORD TRAUMA Genovese T, Mazzon E, Esposito E, Di Paola R, Caminiti R, Meli R, Bramanti P, Cuzzocrea S.. Shock. 2008 Sep;30(3):231-40. I.F.3,394

77.EVIDENCE FOR THE ROLE OF MITOGEN-ACTIVATED PROTEIN KINASE SIGNALING PATHWAYS IN THE DEVELOPMENT OF SPINAL CORD INJURY Genovese T, Esposito E, Mazzon E, Muià C, Di Paola R, Meli R, Bramanti P, Cuzzocrea S.. J Pharmacol Exp Ther. 2008 Apr;325(1):100-14. I.F.4,309.

78. ABSENCE OF ENDOGENOUS INTERLEUKIN-10 ENHANCED ORGAN DYSFUNCTION AND MORTALITY ASSOCIATED TO ZYMOSAN-INDUCED MULTIPLE ORGAN DYSFUNCTION SYNDROME.Malleo G, Mazzon E, Genovese T, Di Paola R, Caminiti R, Esposito E, Bramanti P, Cuzzocrea S. Cytokine. 2008 Feb;41(2):136-43. I.F.2,212

79. SIGNAL TRANSDUCTION PATHWAYS INVOLVED IN PROTECTIVE EFFECTS OF MELATONIN IN C6 GLIOMA CELLS Esposito E, Iacono A, Muià C, Crisafulli C, Mattace Raso G, Bramanti P, Meli R, Cuzzocrea S.. J Pineal Res. 2008 Jan;44(1):78-87. I.F.5,056

80. EFFECTS OF GLYCOGEN SYNTHASE KINASE-3BETAINHIBITION ON THE DEVELOPMENT OF CERULEIN-INDUCED ACUTE PANCREATITIS IN MICE.Cuzzocrea S, Malleo G, Genovese T, Mazzon E, Esposito E, Muià C, Abdelrahman M, Di Paola R, Thiemermann C. Crit Care Med. 2007 Dec;35(12):2811-21. I.F.6,594

81. EMBOLIA CUTIS MEDICAMENTOSA FOLLOWING THIOCOLCHICOSIDE INJECTION.Guarneri C, Polimeni G, Guarneri F, Cuzzocrea S. J Eur Acad Dermatol Venereol. 2008Aug;22(8):1005-6. I.F.2,276

82. EFFECTS OF ZILEUTON AND MONTELUKAST IN MOUSEEXPERIMENTAL SPINAL CORD INJURY.Genovese T, Rossi A, Mazzon E, Di Paola R, Muià C, Caminiti R, Bramanti P,Sautebin L, Cuzzocrea S. Br J Pharmacol. 2008 Feb;153(3):568-82. I.F.4,902

83. CERAMIDE: A KEY SIGNALING MOLECULE IN A GUINEA PIG MODEL OF ALLERGIC ASTHMATIC RESPONSE AND AIRWAY INFLAMMATION. Masini E, Giannini L, Nistri S, Cinci L, Mastroianni R, Xu W, Comhair SA, Li D, Cuzzocrea S, Matuschak GM, Salvemini D. J Pharmacol Exp Ther. 2008 Feb;324(2):548-57. I.F.4,309

84. VACCINATION WITH IL-6 ANALOGUES INDUCES AUTOANTIBODIES TO IL-6 AND INFLUENCES EXPERIMENTALLY INDUCED INFLAMMATION Galle P, Jensen L, Andersson C, Cuzzocrea S, Di Paola R, Nicoletti F, Svenson M, Bendtzen K, Thomsen AR, Hansen MB.. Int Immunopharmacol. 2007 Dec 15;7(13):1704-13. I.F.2,157

85.PEROXISOME PROLIFERATOR-ACTIVATEDRECEPTOR-ALPHA CONTRIBUTES TO THE ANTI-INFLAMMATORY ACTIVITY OF GLUCOCORTICOIDS Cuzzocrea S, Bruscoli S, Mazzon E, Crisafulli C, Donato V, Di Paola R, Velardi E, Esposito E, Nocentini G, Riccardi C. Mol Pharmacol. 2008 Feb;73(2):323-37. I.F.4,711

86. THE ROLE OF NITRIC OXIDE SYNTHASES IN LUNG INFLAMMATION.Esposito E, Cuzzocrea S. Curr Opin Investig Drugs. 2007 Nov;8(11):899-909. Review. I.F.2,276

87. THERAPEUTIC MANIPULATION OF PEROXYNITRITE ATTENUATES THE DEVELOPMENT OF OPIATE-INDUCED ANTINOCICEPTIVE TOLERANCE IN MICE Muscoli C, Cuzzocrea S, Ndengele MM, Mollace V, Porreca F, Fabrizi F, Esposito E, Masini E, Matuschak GM, Salvemini D.. J Clin Invest. 2007 Nov;117(11):3530-9. I.F.16,559

88. ROLE OF TNF-ALPHA IN LUNG TIGHT JUNCTION ALTERATION IN MOUSE MODEL OF ACUTE LUNG INFLAMMATION. Mazzon E, Cuzzocrea S. Respir Res. 2007 Oct 30;8:75. I.F.3,874

89. COMBINATION OF DEXAMETHASONE AND ETANERCEPTREDUCES SECONDARY DAMAGE IN EXPERIMENTAL SPINAL CORD TRAUMA Genovese T, Mazzon E, Crisafulli C, Esposito E, Di Paola R, Muià C, Di Bella P, Meli R, Bramanti P, Cuzzocrea S.. Neuroscience. 2007Nov 30;150(1):168-81. I.F.3,556

90. GLYCOGEN SYNTHASE KINASE-3BETA INHIBITIONATTENUATES THE DEVELOPMENT OF BLEOMYCIN-INDUCED LUNG INJURY Cuzzocrea S, Genovese T, Mazzon E, Esposito E, Muià C, Abdelrahman M, DiPaola R, Bramanti P, Thiemermann C.. Int J ImmunopatholPharmacol. 2007 Jul-Sep;20(3):619-30. I.F.2,793

91.MODULATION OF ACUTE AND CHRONIC INFLAMMATION OF THE LUNG BY GITR AND ITS LIGAND.

Nocentini G, Cuzzocrea S, Bianchini R, Mazzon E, Riccardi C. Ann N Y AcadSci. 2007 Jun;1107:380-91. Review. I.F.1,731

92.ETANERCEPT REDUCES ACUTE TISSUE INJURY AND MORTALITYASSOCIATED TO ZYMOSAN-INDUCED MULTIPLE ORGAN DYSFUNCTION SYNDROME Malleo G, Mazzon E, Genovese T, Di Paola R, Muià C, Caminiti R, Esposito E, Di Bella P, Cuzzocrea S.. Shock. 2008 May;29(5):560-71. I.F.3,394

93.PEROXISOME PROLIFERATOR-ACTIVATED RECEPTORS AND ACUTE LUNG INJURY.Paola RD, Cuzzocrea S. PPAR Res. 2007;2007:63745. I.F.

94.EFFECT OF 17BETA-ESTRADIOL ON SIGNALTRANSDUCTION PATHWAYS AND SECONDARY DAMAGE IN EXPERIMENTAL SPINAL CORD TRAUMA Cuzzocrea S, Genovese T, Mazzon E, Esposito E, Di Paola R, Muià C, Crisafulli C, Peli A, Bramanti P, Chaudry IH..Shock. 2008 Mar;29(3):362-71. I.F. 3,394

95.EFFECT OF CHRONIC NICOTINE ADMINISTRATION ON THE RAT LUNG AND LIVER: BENEFICIAL ROLE OF MELATONIN El-Sokkary GH, Cuzzocrea S, Reiter RJ.. Toxicology. 2007 Sep 24;239(1-2):60-7. I.F. 2,836

96.ROLE OF ENDOGENOUS GLUTATHIONE IN THE SECONDARY DAMAGE IN EXPERIMENTAL SPINAL CORD INJURY IN MICE.Genovese T, Mazzon E, Esposito E, Muià C, Di Paola R, Di Bella P, BramantiP, Cuzzocrea S. Neurosci Lett. 2007 Aug 9;423(1):41-6. I.F. 2,200

97. BENEFICIAL EFFECTS OF FETSPP, A PEROXYNITRITE DECOMPOSITION CATALYST, IN AMOUSE MODEL OF SPINAL CORD INJURY Genovese T, Mazzon E, Esposito E, Muià C, Di Paola R, Bramanti P, Cuzzocrea S.. Free Radic Biol Med. 2007 Sep 1;43(5):763-80. I.F. 5,339

98. EFFECTS OF COMBINATION OF MELATONIN AND DEXAMETHASONEON SECONDARY INJURY IN AN EXPERIMENTAL MICE MODEL OF SPINAL CORD TRAUMA Genovese T, Mazzon E, Crisafulli C, Esposito E, Di Paola R, Muià C, Di Bella P, Bramanti P, Cuzzocrea S.. J PinealRes. 2007 Sep;43(2):140-53. I.F. 5,056

99. TNF-ALPHA BLOCKAGE IN A MOUSE MODEL OF SCI: EVIDENCE FOR IMPROBE OUTCOME.Genovese T, Mazzon E, Crisafulli C, Di Paola R, Muià C, Esposito E, Bramanti P, Cuzzocrea S. Shock. 2008 Jan;29(1):32-41. I.F. 3,394

100. INHIBITION OF INDUCIBLE NITRIC OXIDE SYNTHASE IN VITRO AND IN VIVO BY A WATER-SOLUBLE EXTRACT OF WENDITA CALYSINA LEAVES.Marzocco S, Piccinelli AL, Rastrelli L, Mazzon E, Cuzzocrea S, Autore G. Naunyn Schmiedebergs Arch Pharmacol. 2007 Aug;375(6):349-58. I.F. 2,161

101. ACUTE INTRACEREBROVENTRICULAR ADMINISTRATION OF PALMITOYLETHANOLAMIDE, AN ENDOGENOUS PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR-ALPHA AGONIST, MODULATES CARRAGEENAN-INDUCED PAW EDEMA IN MICE.D'Agostino G, La Rana G, Russo R, Sasso O, Iacono A, Esposito E, Raso GM, Cuzzocrea S, Lo Verme J, Piomelli D, Meli R, Calignano A. J Pharmacol Exp Ther. 2007 Sep;322(3):1137-43. I.F. 4,309

102. ROLE OF TUMOR NECROSIS FACTOR-ALPHA IN ACUTE PANCREATITIS: FROM BIOLOGICAL BASIS TO CLINICAL EVIDENCE Malleo G, Mazzon E, Siriwardena AK, Cuzzocrea S..Shock. 2007 Aug;28(2):130-40. Review. I.F. 3,394

103. ABSENCE OF FUNCTIONAL PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR-ALPHA ENHANCED ILEUM PERMEABILITY DURING EXPERIMENTAL COLITIS Mazzon E, Cuzzocrea S.. Shock. 2007 Aug;28(2):192-201. I.F. 3,394

104. NITRIC OXIDE IN THE INJURED SPINAL CORD: SYNTHASES CROSS-TALK, OXIDATIVE STRESS AND INFLAMMATION. Conti A, Miscusi M, Cardali S, Germanò A, Suzuki H, Cuzzocrea S, Tomasello F. Brain Res Rev. 2007 Apr;54(1):205-18. Review. I.F. 6,236

105. TNF-ALPHA AS A THERAPEUTIC TARGET IN ACUTE PANCREATITIS--LESSONS FROM EXPERIMENTAL MODELS Malleo G, Mazzon E, Siriwardena AK, Cuzzocrea S.. ScientificWorldJournal. 2007 Mar 30;7:431-48. Review. I.F. 1,830

106. PROTECTIVE ROLE OF PI3-KINASE-AKT-ENOS SIGNALLING PATHWAY IN INTESTINAL INJURY ASSOCIATED WITH SPLANCHNIC ARTERY OCCLUSION SHOCK Roviezzo F, Cuzzocrea S, Di Lorenzo A, Brancaleone V, Mazzon E, Di Paola R, Bucci M, Cirino G.. Br J Pharmacol. 2007 Jun;151(3):377-83. Epub 2007 Apr 23; I.F. 4,902

107. IN VITRO, EX VIVO AND IN VIVO IMMUNOPHARMACOLOGICAL ACTIVITIES OF THE ISOXAZOLINE COMPOUND VGX-1027: MODULATION OF CYTOKINE SYNTHESIS AND PREVENTION OF BOTH ORGAN-SPECIFIC AND SYSTEMIC AUTOIMMUNE DISEASES IN MURINE MODELSStojanovic I, Cuzzocrea S, Mangano K, Mazzon E, Miljkovic D, Wang M, DoniaM, Al Abed Y, Kim J, Nicoletti F, Stosic-Grujicic S, Claesson M.. Clin Immunol. 2007 Jun;123(3):311-23. I.F. 3,606

108. ETANERCEPT ATTENUATES THE DEVELOPMENT OF CERULEIN-INDUCED ACUTE PANCREATITIS IN MICE: A COMPARISON WITH TNF-ALPHA GENETIC DELETION

Malleo G, Mazzon E, Genovese T, Di Paola R, Muià C, Centorrino T, Siriwardena AK, Cuzzocrea S.. Shock. 2007 May;27(5):542-51. I.F. 3,394

109. INHIBITION OF TYROSINE KINASE-MEDIATED CELLULAR SIGNALLING BY TYRPHOSTINS AG126 AND AG556 MODULATES SECONDARY DAMAGE IN EXPERIMENTAL SPINAL CORD TRAUMA. Genovese T, Mazzon E, Esposito E, Muià C, Di Paola R, Crisafulli C, Bramanti P, Cuzzocrea S. Neuropharmacology. 2007 Jun;52(7):1454-71. I.F. 3,383

110. BENEFICIAL EFFECTS OF A PLANT HISTAMINASE IN A RAT MODEL OF SPLANCHNIC ARTERY OCCLUSION AND REPERFUSION. Masini E, Cuzzocrea S, Bani D, Mazzon E, Muja C, Mastroianni R, Fabrizi F, Pietrangeli P, Marcocci L, Mondovì B, Mannaioni PF, Federico R. Shock. 2007 Apr;27(4):409-15. I.F. 3,394

111. GITR/GITRL: MORE THAN AN EFFECTOR T CELL CO-STIMULATORY SYSTEM. Nocentini G, Ronchetti S, Cuzzocrea S, Riccardi C. Eur J Immunol. 2007 May;37(5):1165-9. I.F. 4,865

112. PEROXISOME PROLIFERATOR-ACTIVATED RECEPTORS LIGANDS AND ISCHEMIA-REPERFUSION INJURY. Di Paola R, Cuzzocrea S. Naunyn Schmiedebergs Arch Pharmacol. 2007 May;375(3):157-75. I.F. 2,161

113. GLYCOGEN SYNTHASE KINASE-3BETA INHIBITION ATTENUATES THE DEVELOPMENT OF ISCHAEMIA/REPERFUSION INJURY OF THE GUT Cuzzocrea S, Mazzon E, Esposito E, Muià C, Abdelrahman M, Di Paola R, Crisafulli C, Bramanti P, Thiemermann C.. Intensive Care Med. 2007 May;33(5):880-93 I.F. 5,055

114. THE ROLE OF CYCLOXYGENASE-2 IN THE RODENT KIDNEY FOLLOWING ISCHAEMIA/REPERFUSION INJURY IN VIVO Patel NS, Cuzzocrea S, Collino M, Chaterjee PK, Mazzon E, Britti D, Yaqoob MM, Thiemermann C.. Eur J Pharmacol. 2007 May 7;562(1-2):148-54. I.F. 2,787

115. THE ROLE OF 5-LIPOXYGENASE AND LEUKOTRIENES IN SHOCK AND ISCHEMIA-REPERFUSION INJURY. Rossi A, Pergola C, Cuzzocrea S, Sautebin L. ScientificWorldJournal. 2007 Jan 22;7:56-74. Review. I.F. 1,830

116. 5-AMINOISOQUINOLIN-1(2H)-ONE, A WATER-SOLUBLE POLY (ADP-RIBOSE) POLYMERASE (PARP) INHIBITOR REDUCES THE EVOLUTION OF EXPERIMENTAL PERIODONTITIS IN RATS Di Paola R, Mazzon E, Muià C, Terrana D, Greco S, Britti D, Santori D, Oteri G, Cordasco G, Cuzzocrea S.. J Clin Periodontol. 2007 Feb;34(2):95-102. I.F. 3,193

117. N-BENZYLOXYCARBONYL-VAL-ALA-ASP-FLUOROMETHYLKETONE REDUCES SEVERITY OF EXPERIMENTAL SPINAL CORD INJURY Genovese T, Mazzon E, Esposito E, Muià C, Di Paola R, Crisafulli C, Bramanti P, Cuzzocrea S.. Shock. 2007 Mar;27(3):258-65. I.F. 3,394

118. AMINO ACID LEVELS IN SOME BRAIN AREAS OF INDUCIBLE NITRIC OXIDE SYNTHASE KNOCK OUT MOUSE (INOS-/-) BEFORE AND AFTER PENTYLENETETRAZOLE KINDLING.De Luca G, Di Giorgio RM, Macaione S, Calpona PR, Di Paola ED, Costa N, Cuzzocrea S, Citraro R, Russo E, De Sarro G. Pharmacol Biochem Behav. 2006 Dec;85(4):804-12. I.F. 2,751

119. PROTECTIVE EFFECT OF ORALLY ADMINISTERED CARNOSINE ON BLEOMYCIN-INDUCED LUNG INJURY.Cuzzocrea S, Genovese T, Failla M, Vecchio G, Fruciano M, Mazzon E, Di Paola R, Muià C, La Rosa C, Crimi N, Rizzarelli E, Vancheri C. Am J Physiol Lung Cell Mol Physiol. 2007 May;292(5):L1095-104. I.F. 3,924

120. SPLANCHNIC ISCHEMIA AND REPERFUSION INJURY IS REDUCED BY GENETIC OR PHARMACOLOGICAL INHIBITION OF TNF-ALPHA. Esposito E, Mazzon E, Muià C, Meli R, Sessa E, Cuzzocrea S. J Leukoc Biol. 2007 Apr;81(4):1032-43. I.F. 4,605

121. NITRITE-DERIVED NITRIC OXIDE PROTECTS THE RAT KIDNEY AGAINST ISCHEMIA/REPERFUSION INJURY IN VIVO: ROLE FOR XANTHINE OXIDOREDUCTASE. Tripatara P, Patel NS, Webb A, Rathod K, Lecomte FM, Mazzon E, Cuzzocrea S, Yaqoob MM, Ahluwalia A, Thiemermann C. J Am Soc Nephrol. 2007 Feb;18(2):570-80. Epub 2007 Jan 3. I.F. 7,505

122. MOLECULAR MECHANISMS INVOLVED IN THE RECIPROCAL REGULATION OF CYCLOOXYGENASE AND NITRIC OXIDE SYNTHASE ENZYMES Cuzzocrea S, Salvemini D.. Kidney Int. 2007 Feb;71(4):290-7. Epub 2007 Jan 3. Review. I.F. 6,418

123. EFFECTS OF ETANERCEPT, A TUMOUR NECROSIS FACTOR-ALPHA ANTAGONIST, IN AN EXPERIMENTAL MODEL OF PERIODONTITIS IN RATS Di Paola R, Mazzon E, Muià C, Crisafulli C, Terrana D, Greco S, Britti D, Santori D, Oteri G, Cordasco G, Cuzzocrea S.. Br J Pharmacol. 2007 Feb;150(3):286-97. I.F. 4,902

124. PEROXISOME PROLIFERATOR-ACTIVATED RECEPTORS AND SHOCK STATE. Esposito E, Cuzzocrea S, Meli R. ScientificWorldJournal. 2006 Dec 28;6:1770-82. Review. I.F. 1,830

125. GLYCOGEN SYNTHASE KINASE 3BETA INHIBITION REDUCES THE DEVELOPMENT OF NONSEPTIC SHOCK INDUCED BY ZYMOSAN IN MICE. Cuzzocrea S, Di Paola R, Mazzon E, Crisafulli C, Genovese T, Muià C, Abdelrahman M, Esposito E, Thiemermann C. Shock. 2007 Jan;27(1):97-107. I.F. 3,394

126. ROLE OF POLY(ADP-RIBOSE) GLYCOHYDROLASE IN THE DEVELOPMENT OF INFLAMMATORY BOWEL DISEASE IN MICE Cuzzocrea S, Mazzon E, Genovese T, Crisafulli C, Min WK, Di Paola R, Muià C, Li JH, Malleo G, Xu W, Massuda E, Esposito E, Zhang J, Wang ZQ.. Free Radic Biol Med. 2007 Jan 1;42(1):90-105. I.F. 5,399

127. GENETIC AND PHARMACOLOGICAL INHIBITION OF GITR-GITRL INTERACTION REDUCES CHRONIC LUNG INJURY INDUCED BY BLEOMYCIN INSTILLATION Cuzzocrea S, Ronchetti S, Genovese T, Mazzon E, Agostini M, Di Paola R, Esposito E, Muià C, Nocentini G, Riccardi C.. FASEB J. 2007 Jan;21(1):117-29. I.F. 7,049

128. PHARMACOLOGICAL INHIBITION OF LEUKOTRIENES IN AN ANIMAL MODEL OF BLEOMYCIN-INDUCED ACUTE LUNG INJURY Failla M, Genovese T, Mazzon E, Gili E, Muià C, Sortino M, Crimi N, Caputi AP, Cuzzocrea S, Vancheri C.. Respir Res. 2006 Nov 21;7:137. I.F. 3,874

129. SUPEROXIDE, PEROXYNITRITE AND OXIDATIVE/NITRATIVE STRESS IN INFLAMMATION.Salvemini D, Doyle TM, Cuzzocrea S. Biochem Soc Trans. 2006 Nov;34(Pt 5):965-70. I.F. 2,979

130. ABSENCE OF PEROXISOME PROLIFERATORS-ACTIVATED RECEPTORS (PPAR)ALPHA ENHANCED THE MULTIPLE ORGAN FAILURE INDUCED BY ZYMOSAN Di Paola R, Esposito E, Mazzon E, Genovese T, Muià C, Crisafulli C, Malleo G, Sessa E, Meli R, Cuzzocrea S.. Shock. 2006 Nov;26(5):477-84. I.F. 3,394

131. ESTROGEN RECEPTOR ANTAGONIST FULVESTRANT (ICI 182,780) INHIBITS THE ANTI-INFLAMMATORY EFFECT OF GLUCOCORTICOIDS Cuzzocrea S, Bruscoli S, Crisafulli C, Mazzon E, Agostini M, Muià C, Esposito E, Di Virgilio R, Meli R, Vegeto E, Maggi A, Riccardi C.. Mol Pharmacol. 2007 Jan;71(1):132-44. I.F. 4,711

132. ROLE OF NITRIC OXIDE AND REACTIVE OXYGEN SPECIES IN ARTHRITIS Cuzzocrea S.. Curr Pharm Des. 2006;12(27):3551-70. Review. I.F. 4,399

133. INHIBITION OF GLYCOGEN SYNTHASE KINASE-3BETA ATTENUATES THE DEVELOPMENT OF CARRAGEENAN-INDUCED LUNG INJURY IN MICE Cuzzocrea S, Crisafulli C, Mazzon E, Esposito E, Muià C, Abdelrahman M, Di Paola R, Thiemermann C.. Br J Pharmacol. 2006 Nov;149(6):687-702. I.F. 4,902

134. MELATONIN MODULATES SIGNAL TRANSDUCTION PATHWAYS AND APOPTOSIS IN EXPERIMENTAL COLITIS. Mazzon E, Esposito E, Crisafulli C, Riccardi L, Muià C, Di Bella P, Meli R, Cuzzocrea S. J Pineal Res. 2006 Nov;41(4):363-73. I.F. 5,056

135. DESIGN OF A NEW LINE IN TREATMENT OF EXPERIMENTAL RHEUMATOID ARTHRITIS BY ARTESUNATE Mirshafiey A, Saadat F, Attar M, Di Paola R, Sedaghat R, Cuzzocrea S.. Immunopharmacol Immunotoxicol. 2006;28(3):397-410. I.F. 0,822

136. COPPER ACTIVATES THE NF-KAPPAB PATHWAY IN VIVO.Persichini T, Percario Z, Mazzon E, Colasanti M, Cuzzocrea S, Musci G. Antioxid Redox Signal. 2006 Sep-Oct;8(9-10):1897-904. I.F. 6,190

137. GREEN TEA POLYPHENOL EXTRACT ATTENUATES ZYMOSAN-INDUCED NON-SEPTIC SHOCK IN MICE.Di Paola R, Mazzon E, Muià C, Crisafulli C, Genovese T, Di Bella P, Esposito E, Menegazzi M, Meli R, Suzuki H, Cuzzocrea S. Shock. 2006 Oct;26(4):402-9. I.F. 3,394

138. EFFECTS OF 3-AMINOBENZAMIDE, AN INHIBITOR OF POLY (ADP-RIBOSE) POLYMERASE, IN A MOUSE MODEL OF ACUTE PANCREATITIS INDUCED BY CERULEIN. Mazzon E, Genovese T, Di Paola R, Muià C, Crisafulli C, Malleo G, Esposito E, Meli R, Sessa E, Cuzzocrea S. Eur J Pharmacol. 2006 Nov 7;549(1-3):149-56. I.F. 2,787

139. HYPERBARIC OXYGEN THERAPY PREVENTS COAGULATION DISORDERS IN AN EXPERIMENTAL MODEL OF MULTIPLE ORGAN FAILURE SYNDROME. Imperatore F, Cuzzocrea S, De Lucia D, Sessa M, Rinaldi B, Capuano A, Liguori G, Filippelli A, Rossi F. Intensive Care Med. 2006 Nov;32(11):1881-8. I.F. 5,055

140. OXIDATIVE STRESS AS THE LEADING CAUSE OF ACUTE MYOCARDIAL INFARCTION IN DIABETICS.Di Filippo C, Cuzzocrea S, Rossi F, Marfella R, D'Amico M. Cardiovasc Drug Rev. 2006 Summer;24(2):77-87. Review. I.F. 4,114

141. EFFECTS OF COMBINATION OF MELATONIN AND DEXAMETHASONE ON ACUTE LUNG INJURY IN A MICE MODEL OF CARRAGEENAN-INDUCED PLEURISY Crisafulli C, Mazzon E, Muià C, Bella P, Esposito E, Meli R, Cuzzocrea S.. J Pineal Res. 2006 Oct;41(3):228-37. I.F. 5,056

142. PROTECTIVE EFFECT OF HYPERICUM PERFORATUM IN ZYMOSAN-INDUCED MULTIPLE ORGAN DYSFUNCTION SYNDROME: RELATIONSHIP TO ITS INHIBITORY EFFECT ON NITRIC OXIDE PRODUCTION AND ITS PEROXYNITRITE SCAVENGING ACTIVITY.

Di Paola R, Mazzon E, Muià C, Crisafulli C, Genovese T, Di Bella P, Esposito E, Menegazzi M, Meli R, Suzuki H, Cuzzocrea S. Nitric Oxide. 2007 Feb;16(1):118-30. I.F. 2,650

143. PROTECTIVE EFFECTS OF RELAXIN IN ISCHEMIA/REPERFUSION-INDUCED INTESTINAL INJURY DUE TO SPLANCHNIC ARTERY OCCLUSION.Masini E, Cuzzocrea S, Mazzon E, Muià C, Vannacci A, Fabrizi F, Bani D. Br J Pharmacol. 2006 Aug;148(8):1124-32. I.F. 4,902

144. POLY(ADP-RIBOSE) GLYCOHYDROLASE ACTIVITY MEDIATES POST-TRAUMATIC INFLAMMATORY REACTION AFTER EXPERIMENTAL SPINAL CORD TRAUMA Cuzzocrea S, Genovese T, Mazzon E, Crisafulli C, Min W, Di Paola R, Muià C, Li JH, Esposito E, Bramanti P, Xu W, Massuda E, Zhang J, Wang ZQ.. J Pharmacol Exp Ther. 2006 Oct;319(1):127-38. I.F. 4,309

145. ASPIRIN REGULATES EXPRESSION AND FUNCTION OF SCAVENGER RECEPTOR-BI IN MACROPHAGES: STUDIES IN PRIMARY HUMAN MACROPHAGES AND IN MICE Tancevski I, Wehinger A, Schgoer W, Eller P, Cuzzocrea S, Foeger B, Patsch JR, Ritsch A.. FASEB J. 2006 Jul;20(9):1328-35. I.F. 7,049

146. A ROLE FOR NITRIC OXIDE-MEDIATED PEROXYNITRITE FORMATION IN A MODEL OF ENDOTOXIN-INDUCED SHOCK Cuzzocrea S, Mazzon E, Di Paola R, Esposito E, Macarthur H, Matuschak GM, Salvemini D.. J Pharmacol Exp Ther. 2006 Oct;319(1):73-81. I.F. 4,309

147. INHIBITION OF POLY(ADP-RIBOSE) POLYMERASE PREVENTS IRINOTECAN-INDUCED INTESTINAL DAMAGE AND ENHANCES IRINOTECAN/TEMOZOLOMIDE EFFICACY AGAINST COLON CARCINOMA. Tentori L, Leonetti C, Scarsella M, Muzi A, Mazzon E, Vergati M, Forini O, Lapidus R, Xu W, Dorio AS, Zhang J, Cuzzocrea S, Graziani G. FASEB J. 2006 Aug;20(10):1709-11. I.F. 7,049

148. PROINFLAMMATORY ROLE OF GLUCOCORTICOID-INDUCED TNF RECEPTOR-RELATED GENE IN ACUTE LUNG INFLAMMATION Cuzzocrea S, Nocentini G, Di Paola R, Agostini M, Mazzon E, Ronchetti S, Crisafulli C, Esposito E, Caputi AP, Riccardi C.. J Immunol. 2006 Jul 1;177(1):631-41. I.F. 6

149. ROLE OF PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR-ALPHA IN ACUTE PANCREATITIS INDUCED BY CERULEIN Genovese T, Mazzon E, Di Paola R, Muià C, Crisafulli C, Malleo G, Esposito E, Cuzzocrea S.. Immunology. 2006 Aug;118(4):559-70. I.F. 3,432

150. NEUROPROTECTION AND ENHANCED RECOVERY WITH HYPERICUM PERFORATUM EXTRACT AFTER EXPERIMENTAL SPINAL CORD INJURY IN MICE. Genovese T, Mazzon E, Menegazzi M, Di Paola R, Muià C, Crisafulli C, Bramanti P, Suzuki H, Cuzzocrea S. Shock. 2006 Jun;25(6):608-17. I.F. 3,394

151. PYRROLIDINE DITHIOCARBAMATE REDUCED EXPERIMENTAL PERIODONTITIS Muià C, Mazzon E, Maiere D, Zito D, Di Paola R, Domenico S, Crisafulli C, Britti D, Cuzzocrea S.. Eur J Pharmacol. 2006 Jun 13;539(3):205-10. I.F. 2,787

152. THALIDOMIDE TREATMENT REDUCES THE ALTERATION OF PARACELLULAR BARRIER FUNCTION IN MICE ILEUM DURING EXPERIMENTAL COLITIS Mazzon E, Cuzzocrea S.. Shock. 2006 May;25(5):515-21. I.F. 3,394

153. GLYCOGEN SYNTHASE KINASE-3BETA INHIBITORS PROTECT AGAINST THE ORGAN INJURY AND DYSFUNCTION CAUSED BY HEMORRHAGE AND RESUSCITATION Dugo L, Abdelrahman M, Murch O, Mazzon E, Cuzzocrea S, Thiemermann C.. Shock. 2006 May;25(5):485-91. I.F. 3,394

154. 5-LIPOXYGENASE MODULATES THE ALTERATION OF PARACELLULAR BARRIER FUNCTION IN MICE ILEUM DURING EXPERIMENTAL COLITIS. Mazzon E, Sautebin L, Caputi AP, Cuzzocrea S. Shock. 2006 Apr;25(4):377-83. I.F. 3,394

155. GLYCOGEN SYNTHASE KINASE-3BETA INHIBITION ATTENUATES THE DEGREE OF ARTHRITIS CAUSED BY TYPE II COLLAGEN IN THE MOUSE Cuzzocrea S, Mazzon E, Di Paola R, Muià C, Crisafulli C, Dugo L, Collin M, Britti D, Caputi AP, Thiemermann C.. Clin Immunol. 2006 Jul;120(1):57-67. I.F. 3,606

156. GLYCOGEN SYNTHASE KINASE-3 BETA INHIBITION REDUCES SECONDARY DAMAGE IN EXPERIMENTAL SPINAL CORD TRAUMA Cuzzocrea S, Genovese T, Mazzon E, Crisafulli C, Di Paola R, Muià C, Collin M, Esposito E, Bramanti P, Thiemermann C.. J Pharmacol Exp Ther. 2006 Jul;318(1):79-89. I.F. 4,309

157. A NOVEL ADAMANTANE DERIVATIVE ATTENUATES RETINALISCHEMIA-REPERFUSION DAMAGE IN THE RAT RETINA THROUGH SIGMA1 RECEPTORS Bucolo C, Marrazzo A, Ronsisvalle S, Ronsisvalle G, Cuzzocrea S, Mazzon E, Caputi A, Drago F.. Eur J Pharmacol. 2006 Apr 24;536(1-2):200-3. I.F. 2,787

158. PEROXISOME PROLIFERATOR-ACTIVATED RECEPTORS AND ACUTE LUNG INJURY Cuzzocrea S.. Curr Opin Pharmacol. 2006 Jun;6(3):263-70. Review. I.F. 6,528

159. CLORICROMENE, A COUMARINE DERIVATIVE, REDUCED THE DEVELOPMENT OF PERIODONTITIS IN RATS Muià C, Mazzon E, Zito D, Maiere D, Britti D, Crisafulli C, Oteri G, Cordasco G, Cuzzocrea S.. Naunyn Schmiedebergs Arch Pharmacol. 2006 Apr;373(1):51-9. I.F. 2,161

160. ANTI-ALLERGIC PROPERTIES OF MANGIFERA INDICA L. EXTRACT (VIMANG) AND CONTRIBUTION OF ITS GLUCOSYLXANTHONE MANGIFERIN Rivera DG, Balmaseda IH, León AA, Hernández BC, Montiel LM, Garrido GG, Cuzzocrea S, Hernández RD.. J Pharm Pharmacol. 2006 Mar;58(3):385-92. I.F. 1,847

161. HYPERICUM PERFORATUM ATTENUATES THE DEVELOPMENT OF CERULEIN-INDUCED ACUTE PANCREATITIS IN MICE. Genovese T, Mazzon E, Di Paola R, Muià C, Crisafulli C, Menegazzi M, Malleo G, Suzuki H, Cuzzocrea S. Shock. 2006 Feb;25(2):161-7. I.F. 3,394

162. HYPERICUM PERFORATUM ATTENUATES THE DEVELOPMENT OF CARRAGEENAN-INDUCED LUNG INJURY IN MICE Menegazzi M, Di Paola R, Mazzon E, Muià C, Genovese T, Crisafulli C, Suzuki H, Cuzzocrea S.. Free Radic Biol Med. 2006 Mar 1;40(5):740-53. I.F. 5,399

163. INHIBITION OF NITRIC OXIDE BIOSYNTHESIS BY ANTHOCYANIN FRACTION OF BLACKBERRY EXTRACT Pergola C, Rossi A, Dugo P, Cuzzocrea S, Sautebin L.. Nitric Oxide. 2006 Aug;15(1):30-9. I.F. 2,650

164. MODULATION OF NITRIC OXIDE HOMEOSTASIS IN A MOUSE MODEL OF SPINAL CORD INJURY Genovese T, Mazzon E, Mariotto S, Menegazzi M, Cardali S, Conti A, Suzuki H, Bramanti P, Cuzzocrea S.. J Neurosurg Spine. 2006 Feb;4(2):145-53. I.F. 1,403

165. THE ROLE OF THE PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR-ALPHA (PPAR-ALPHA) IN THE REGULATION OF ACUTE INFLAMMATION Cuzzocrea S, Mazzon E, Di Paola R, Peli A, Bonato A, Britti D, Genovese T, Muià C, Crisafulli C, Caputi AP.. J Leukoc Biol. 2006 May;79(5):999-1010. I.F. 4,605

166. TYRPHOSTIN AG 126 REDUCES INTESTINAL ISCHEMIA-REPERFUSION INJURY IN THE RAT Marzocco S, Mazzon E, Pinto A, Autore G, Cuzzocrea S.. Naunyn Schmiedebergs Arch Pharmacol. 2006 Feb;372(5):362-73 I.F. 2,161

167. ERYTHROPOIETIN REDUCES THE DEVELOPMENT OF NONSEPTIC SHOCK INDUCED BY ZYMOSAN IN MICE.Cuzzocrea S, Di Paola R, Mazzon E, Patel NS, Genovese T, Muià C, Crisafulli C, Caputi AP, Thiemermann C. Crit Care Med. 2006 Apr;34(4):1168-77. I.F. 6,594

168. ARTEMETHER: A NEW THERAPEUTIC STRATEGY IN EXPERIMENTAL RHEUMATOID ARTHRITIS. Cuzzocrea S, Saadat F, Di Paola R, Mirshafiey A. Immunopharmacol Immunotoxicol. 2005;27(4):615-30. I.F. 0,822

169. ROSIGLITAZONE REDUCES THE EVOLUTION OF EXPERIMENTAL PERIODONTITIS IN THE RAT Di Paola R, Mazzon E, Maiere D, Zito D, Britti D, De Majo M, Genovese T, Cuzzocrea S.. J Dent Res. 2006 Feb;85(2):156-61. I.F. 3,142

170. ROLE OF ENDOGENOUS PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR-ALPHA (PPAR-ALPHA) LIGANDS IN THE DEVELOPMENT OF GUT ISCHEMIA AND REPERFUSION IN MICE. Muià C, Mazzon E, Crisafulli C, Di Paola R, Genovese T, Caputi AP, Cuzzocrea S. Shock. 2006 Jan;25(1):17-22. I.F. 3,394

171. SYNERGISTIC INTERACTION BETWEEN METHOTREXATE AND A SUPEROXIDE DISMUTASEMIMETIC: PHARMACOLOGIC AND POTENTIAL CLINICAL SIGNIFICANCE Cuzzocrea S, Mazzon E, di Paola R, Genovese T, Muià C, Caputi AP, Salvemini D.. Arthritis Rheum. 2005 Dec;52(12):3755-60. I.F. 6,707

172. ROLEOF ENDOGENOUS AND EXOGENOUS LIGANDS FOR THE PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR alpha IN THE DEVELOPMENT OF BLEOMYCIN-INDUCED LUNG INJURY Genovese T, Mazzon E, Di Paola R, Muià C, Crisafulli C, Caputi AP, Cuzzocrea S.. Shock. 2005 Dec;24(6):547-55. I.F. 3,394

173. TREATMENT WITH PARP-1 INHIBITORS, GPI 15427 OR GPI 16539, AMELIORATES INTESTINAL DAMAGE IN RAT MODELS OF COLITIS AND SHOCK Di Paola R, Mazzon E, Xu W, Genovese T, Ferrraris D, Muià C, Crisafulli C, Zhang J, Cuzzocrea S.. Eur J Pharmacol. 2005 Dec 19;527(1-3):163-71. I.F. 2,787

174. IMMUNOMODULATORY EFFECTS OF ETANERCEPT IN AN EXPERIMENTAL MODEL OF SPINAL CORD INJURY. Genovese T, Mazzon E, Crisafulli C, Di Paola R, Muià C, Bramanti P, Cuzzocrea S. J Pharmacol Exp Ther. 2006 Mar;316(3):1006-16. I.F. 4,309

175. A PROTECTIVE ROLE FOR PROTEINASE ACTIVATED RECEPTOR 2 IN AIRWAYS OF LIPOPOLYSACCHARIDE-TREATED RATS.Morello S, Vellecco V, Roviezzo F, Maffia P, Cuzzocrea S, Cirino G, Cicala C. Biochem Pharmacol. 2005 Dec 19;71(1-2):223-30. I.F. 4,838

176. INHIBITION OF TYROSINE-KINASE-MEDIATED CELLULAR SIGNALING BY TYRPHOSTINS AG 126 AND AG556 MODULATES MURINE EXPERIMENTAL ACUTE PANCREATITIS. Balachandra S, Genovese T, Mazzon E, Di Paola R, Thiemerman C, Siriwardena AK, Cuzzocrea S. Surgery. 2005 Nov;138(5):913-23. I.F. 3,389

177. INCREASED OXIDATIVE-RELATED MECHANISMS IN THE SPINAL CORD INJURY IN OLD RATS. Genovese T, Mazzon E, Di Paola R, Crisafulli C, Muià C, Bramanti P, Cuzzocrea S. Neurosci Lett. 2006 Jan 30;393(2-3):141-6. I.F. 2,200

178. INCREASED GILZ EXPRESSION IN TRANSGENIC MICE UP-REGULATES TH-2 LYMPHOKINES. Cannarile L, Fallarino F, Agostini M, Cuzzocrea S, Mazzon E, Vacca C, Genovese T, Migliorati G, Ayroldi E, Riccardi C. Blood. 2006 Feb 1;107(3):1039-47. I.F. 10,432

179. EFFECTS OF TEMPOL, A MEMBRANE-PERMEABLE RADICAL SCAVENGER, IN A RODENT MODEL PERIODONTITIS. J Di Paola R, Mazzon E, Zito D, Maiere D, Britti D, Genovese T, Cuzzocrea S. Clin Periodontol. 2005 Oct;32(10):1062-8. I.F. 3,193

180. EFFECTS OF HYPERICUM PERFORATUM EXTRACT IN A RAT MODEL OF ISCHEMIA AND REPERFUSION INJURY De Paola R, Muià C, Mazzon E, Genovese T, Crisafulli C, Menegazzi M, Caputi AP, Suzuki H, Cuzzocrea S.. Shock. 2005 Sep;24(3):255-63. I.F. 3,394

181. MELATONIN LIMITS LUNG INJURY IN BLEOMYCIN TREATED MICE Genovese T, Di Paola R, Mazzon E, Muià C, Caputi AP, Cuzzocrea S.. J Pineal Res. 2005 Sep;39(2):105-12. I.F. 5,056

182. GREEN TEA POLYPHENOL EXTRACT ATTENUATES COLON INJURY INDUCED BY EXPERIMENTAL COLITIS Mazzon E, Muià C, Paola RD, Genovese T, Menegazzi M, De Sarro A, Suzuki H, Cuzzocrea S.. Free Radic Res. 2005 Sep;39(9):1017-25. I.F. 2,826

183. ROLE OF GLUCOCORTICOID-INDUCED TNF RECEPTOR FAMILY GENE (GITR) IN COLLAGEN-INDUCED ARTHRITIS Cuzzocrea S, Ayroldi E, Di Paola R, Agostini M, Mazzon E, Bruscoli S, Genovese T, Ronchetti S, Caputi AP, Riccardi C.. FASEB J. 2005 Aug;19(10):1253-65. I.F. 7,049

184. M2000: A REVOLUTION IN PHARMACOLOGY. Mirshafiey A, Cuzzocrea S, Rehm BH, Matsuo H. Med Sci Monit. 2005 Aug;11(8):PI53-63. Epub 2005 Jul 25. I.F. 1,514

185. EFFECT OF PYRIMETHAMINE IN EXPERIMENTAL RHEUMATOID ARTHRITIS

Saadat F, Cuzzocrea S, Di Paola R, Pezeshki M, Khorramizadeh MR, Sedaghat M, Razavi A, Mirshafiey A.. Med Sci Monit. 2005 Aug;11(8):BR293-9. I.F. 1,514

186. UP-REGULATION OF PROSTAGLANDIN BIOSYNTHESIS BY LEUKOTRIENE C4 IN ELICITED MICE PERITONEAL MACROPHAGES ACTIVATED WITH LIPOPOLYSACCHARIDE/INTERFERON-{GAMMA}.Rossi A, Acquaviva AM, Iuliano F, Di Paola R, Cuzzocrea S, Sautebin L. J Leukoc Biol. 2005 Oct;78(4):985-91. I.F. 4,605

187. HYPERBARIC OXYGEN AND SEPSIS: TIME TO RECOGNIZE.Muth CM, Radermacher P, Cuzzocrea S. Intensive Care Med. 2005 Sep;31(9):1150-2. I.F. 5,055

188. INVOLVEMENT OF 5-LIPOXYGENASE IN SPINAL CORD INJURY Genovese T, Mazzon E, Rossi A, Di Paola R, Cannavò G, Muià C, Crisafulli C, Bramanti P, Sautebin L, Cuzzocrea S. J Neuroimmunol. 2005 Sep;166(1-2):55-64. I.F. 3,159

189. GREEN TEA POLYPHENOL EXTRACT ATTENUATES ISCHEMIA/REPERFUSION INJURY OF THE GUT Muià C, Mazzon E, Di Paola R, Genovese T, Menegazzi M, Caputi AP, Suzuki H, Cuzzocrea S.. Naunyn Schmiedebergs Arch Pharmacol. 2005 May;371(5):364-74. I.F. 2,161

190. GREEN TEA POLYPHENOL EXTRACT ATTENUATES LUNG INJURY IN EXPERIMENTAL MODEL OF CARRAGEENAN-INDUCED PLEURISY IN MICE. Di Paola R, Mazzon E, Muià C, Genovese T, Menegazzi M, Zaffini R, Suzuki H, Cuzzocrea S. Respir Res. 2005 Jun 29;6:66. I.F. 3,874

191. INHIBITION OR KNOCK OUT OF INDUCIBLE NITRIC OXIDE SYNTHASE RESULT IN RESISTANCE TO BLEOMYCIN-INDUCED LUNG INJURY Genovese T, Cuzzocrea S, Di Paola R, Failla M, Mazzon E, Sortino MA, Frasca G, Gili E, Crimi N, Caputi AP, Vancheri C.. Respir Res. 2005 Jun 14;6:58. I.F. 3,874

192. EFFECTS OF COMBINATION M40403 AND DEXAMETHASONE THERAPY ON JOINT DISEASE IN A RAT MODEL OF COLLAGEN-INDUCED ARTHRITIS. Cuzzocrea S, Mazzon E, Paola RD, Genovese T, Muià C, Caputi AP, Salvemini D. Arthritis Rheum. 2005 Jun;52(6):1929-40. I.F. 6,787

193. REDUCED DEVELOPMENT OF EXPERIMENTAL PERIODONTITIS BY TREATMENT WITH M40403, A SUPEROXIDE DISMUTASE MIMETIC Di Paola R, Mazzon E, Rotondo F, Dattola F, Britti D, De Majo M, Genovese T, Cuzzocrea S.. Eur J Pharmacol. 2005 Jun 1;516(2):151-7. I.F. 2,787

194. MODULATION OF PROSTAGLANDIN BIOSYNTHESIS BY NITRIC OXIDE AND NITRIC OXIDE DONORS.

Mollace V, Muscoli C, Masini E, Cuzzocrea S, Salvemini D. Pharmacol Rev. 2005 Jun;57(2):217-52. Review. I.F. 21,936

195. ROLE OF POLY(ADP-RIBOSE) GLYCOHYDROLASE (PARG) IN SHOCK, ISCHEMIA AND REPERFUSION. Cuzzocrea S, Wang ZQ. Pharmacol Res. 2005 Jul;52(1):100-8. Review. I.F. 3,287

196. SHOCK, INFLAMMATION AND PARP. Cuzzocrea S. Pharmacol Res. 2005 Jul;52(1):72-82. Review. I.F. 3,287

197. 5-ARYLIDENE-2-IMINO-4-THIAZOLIDINONES: DESIGN AND SYNTHESIS OF NOVEL ANTI-INFLAMMATORY AGENTS Ottanà R, Maccari R, Barreca ML, Bruno G, Rotondo A, Rossi A, Chiricosta G, Di Paola R, Sautebin L, Cuzzocrea S, Vigorita MG. Bioorganic & Medicinal Chemistry 13, Issue 13, 1 July 2005. 4243-4252 I.F. 3,075

198. ROLE OF ENDOGENOUS LIGANDS FOR THE PEROXISOME PROLIFERATORS ACTIVATED RECEPTORS ALPHA IN THE SECONDARY DAMAGE IN EXPERIMENTAL SPINAL CORD TRAUMA. Genovese T, Mazzon E, Di Paola R, Cannavò G, Muià C, Bramanti P, Cuzzocrea S. Exp Neurol. 2005 Jul;194(1):267-78. I.F. 3,974

199. THALIDOMIDE TREATMENT REDUCES COLON INJURY INDUCED BY EXPERIMENTAL COLITIS.Mazzon E, Muià C, Di Paola R, Genovese T, De Sarro A, Cuzzocrea S. Shock. 2005 Jun;23(6):556-64. I.F. 3,394

200. INCREASED CARRAGEENAN-INDUCED ACUTE LUNG INFLAMMATION IN OLD RATS.Corsini E, Di Paola R, Viviani B, Genovese T, Mazzon E, Lucchi L, Marinovich M, Galli CL, Cuzzocrea S. Immunology. 2005 Jun;115(2):253-61. I.F. 3,432

201. TREATMENT OF EXPERIMENTAL ARTHRITIS WITH M2000, A NOVEL DESIGNED NON-STEROIDAL ANTI-INFLAMMATORY DRUG. Mirshafiey A, Cuzzocrea S, Rehm B, Mazzon E, Saadat F, Sotoude M. Scand J Immunol. 2005 May;61(5):435-41. I.F. 2,186

202. THE CYCLOPENTENONE PROSTAGLANDIN 15-DEOXYDELTA(12,14)-PROSTAGLANDIN J2 ATTENUATES THE DEVELOPMENT OF ZYMOSAN-INDUCED SHOCK Marzocco S, Di Paola R, Mazzon E, Genovese T, Britti D, Pinto A, Autore G, Cuzzocrea S.. Intensive Care Med. 2005 May;31(5):693-700. I.F. 5,055

203. 5-LIPOXYGENASE MODULATES COLITIS THROUGH THE REGULATION OF ADHESION EXPRESSION AND NEUTROPHIL MIGRATION

Cuzzocrea S, Rossi A, Mazzon E, Di Paola R, Genovese T, Muià C, Caputi AP, Sautebin L. Laboratory Investigation (2005) 85, 808–822. I.F.4,580

204. PARG ACTIVITY MEDIATES INTESTINAL INJURY INDUCED BY SPLANCHNIC ARTERY OCCLUSION AND REPERFUSION Cuzzocrea S, Di Paola R, Mazzon E, Cortes U, Genovese T, Muià C, Li W, Xu W, Li JH, Zhang J, Wang ZQ.. FASEB J. 2005 Apr;19(6):558-66. I.F. 7,049

205. INHIBITORS OF CALPAIN ACTIVATION (PD150606 AND E-64) AND RENAL ISCHEMIA-REPERFUSION INJURY Chatterjee PK, Todorovic Z, Sivarajah A, Mota-Filipe H, Brown PA, Stewart KN, Mazzon E, Cuzzocrea S, Thiemermann C.. Biochem Pharmacol. 2005 Apr 1;69(7):1121-31. I.F. 4,838

206. ERYTHROPOIETIN REDUCES THE DEGREE OF ARTHRITIS CAUSED BY TYPE II COLLAGEN IN THE MOUSE.Cuzzocrea S, Mazzon E, di Paola R, Genovese T, Patel NS, Britti D, de Majo M, Caputi AP, Thiemermann C. Arthritis Rheum. 2005 Mar;52(3):940-50. I.F. 6,787

207. HYPERGLYCEMIA IN STREPTOZOTOCIN-INDUCED DIABETIC RAT INCREASES INFARCT SIZE ASSOCIATED WITH LOW LEVELS OF MYOCARDIAL HO-1 DURING ISCHEMIA/REPERFUSION.Di Filippo C, Marfella R, Cuzzocrea S, Piegari E, Petronella P, Giugliano D, Rossi F, D'Amico M. Diabetes. 2005 Mar;54(3):803-10. I.F. 8,398

208. URIC ACID PROTECTS AGAINST SECONDARY DAMAGE AFTER SPINAL CORD INJURY.Scott GS, Cuzzocrea S, Genovese T, Koprowski H, Hooper DC. Proc Natl Acad Sci U S A. 2005 Mar 1;102(9):3483-8. I.F. 9,380

209. ATTENUATION IN THE EVOLUTION OF EXPERIMENTAL SPINAL CORD TRAUMA BY TREATMENT WITH MELATONIN Genovese T, Mazzon E, Muià C, Bramanti P, De Sarro A, Cuzzocrea S.. J Pineal Res. 2005 Apr;38(3):198-208. I.F. 5,056

210. EFFECT OF ROSIGLITAZONE AND 15-DEOXY-DELTA12,14-PROSTAGLANDIN J2 ON BLEOMYCIN-INDUCED LUNG INJURY Genovese T, Cuzzocrea S, Di Paola R, Mazzon E, Mastruzzo C, Catalano P, Sortino M, Crimi N, Caputi AP, Thiemermann C, Vancheri C.. Eur Respir J. 2005 Feb;25(2):225-34. I.F. 5,545

211. MICE LACKING THE 110-KD ISOFORM OF POLY(ADP-RIBOSE) GLYCOHYDROLASE ARE PROTECTED AGAINST RENAL ISCHEMIA/REPERFUSION INJURY Patel NS, Cortes U, Di Poala R, Mazzon E, Mota-Filipe H, Cuzzocrea S, Wang ZQ, Thiemermann C.. J Am Soc Nephrol. 2005 Mar;16(3):712-9. I.F. 7,505.

212. INHIBITORS OF NADPH OXIDASE REDUCE THE ORGAN INJURY IN HEMORRHAGIC SHOCK.Abdelrahman M, Mazzon E, Bauer M, Bauer I, Delbosc S, Cristol JP, Patel NS, Cuzzocrea S, Thiemermann C. Shock. 2005 Feb;23(2):107-14. I.F. 3,394

213. BENEFICIAL EFFECTS OF GW274150 TREATMENT ON THE DEVELOPMENT OF EXPERIMENTAL COLITIS INDUCED BY DINITROBENZENE SULFONIC ACID Di Paola R, Mazzon E, Patel NS, Genovese T, Muià C, Thiemermann C, De Sarro A, Cuzzocrea S. Eur J Pharmacol. 2005 Jan 10;507(1-3):281-9. I.F. 2,787.

214. PEROXISOME PROLIFERATOR-ACTIVATED RECEPTORS GAMMA LIGANDS AND ISCHEMIA AND REPERFUSION INJURY Cuzzocrea S. Vascul Pharmacol. 2004 Jul;41(6):187-95. Review. I.F. 2,319

215. INHIBITORS OF POLY(ADP-RIBOSE) POLYMERASE MODULATE SIGNAL TRANSDUCTION PATHWAYS AND THE DEVELOPMENT OF BLEOMYCIN-INDUCED LUNG INJURY Genovese T, Mazzon E, Di Paola R, Muià C, Threadgill MD, Caputi AP, Thiemermann C, Cuzzocrea S.. J Pharmacol Exp Ther. 2005 May;313(2):529-38. I.F. 4,309

216. EFFECT OF METHYLGUANIDINE IN A MODEL OF SEPTIC SHOCK INDUCED BY LPS. Marzocco S, Di Paola R, Ribecco MT, Sorrentino R, Domenico B, Genesio M, Pinto A, Autore G, Cuzzocrea S. Free Radic Res. 2004 Nov;38(11):1143-53. I.F. 2,826

217. 5-AMINOISOQUINOLINONE REDUCES COLON INJURY BY EXPERIMENTAL COLITIS. Cuzzocrea S, Mazzon E, Di Paola R, Genovese T, Patel NS, Muià C, Threadgill MD, De Sarro A, Thiemermann C. Naunyn Schmiedebergs Arch Pharmacol. 2004 Dec;370(6):464-73. Epub 2004 Nov 18. I.F. 2,161

218. ENDOGENOUS INTERLEUKIN-6 ENHANCES THE RENAL INJURY, DYSFUNCTION, AND INFLAMMATION CAUSED BY ISCHEMIA/REPERFUSION Patel NS, Chatterjee PK, Di Paola R, Mazzon E, Britti D, De Sarro A, Cuzzocrea S, Thiemermann C.. J Pharmacol Exp Ther. 2005 Mar;312(3):1170-8. I.F. 4,309

219. DIFFERENTIAL EFFECTS OF CASPASE INHIBITORS ON THE RENAL DYSFUNCTION AND INJURY CAUSED BY ISCHEMIA-REPERFUSION OF THE RAT KIDNEY Chatterjee PK, Todorovic Z, Sivarajah A, Mota-Filipe H, Brown PA, Stewart KN, Cuzzocrea S, Thiemermann C.. Eur J Pharmacol. 2004 Oct 25;503(1-3):173-83. I.F. 2,787

220. TEMPOL REDUCES THE ACTIVATION OF NUCLEAR FACTOR-KAPPAB IN ACUTE INFLAMMATION Cuzzocrea S, Pisano B, Dugo L, Ianaro A, Patel NS, Caputi AP, Thiemermann C.. Free Radic Res. 2004 Aug;38(8):813-9. I.F. 2,826

221. ROLE OF ENDOGENOUS AND EXOGENOUS LIGANDS FOR THE PEROXISOME PROLIFERATORS ACTIVATED RECEPTORS ALPHA (PPAR-ALPHA) IN THE DEVELOPMENT OF INFLAMMATORY BOWEL DISEASE IN MICE. Cuzzocrea S, Di Paola R, Mazzon E, Genovese T, Muià C, Centorrino T, Caputi AP. Lab Invest. 2004 Dec;84(12):1643-54. I.F. 4,580

222. NONCLEAVABLE POLY(ADP-RIBOSE) POLYMERASE-1 REGULATES THE INFLAMMATION RESPONSE IN MICE Pétrilli V, Herceg Z, Hassa PO, Patel NS, Di Paola R, Cortes U, Dugo L, Filipe HM, Thiemermann C, Hottiger MO, Cuzzocrea S, Wang ZQ.. J Clin Invest. 2004 Oct;114(8):1072-81. I.F. 16,559

223. INHIBITION OF THE NUCLEAR FACTOR-KAPPAB ACTIVATION WITH PYRROLIDINE DITHIOCARBAMATE ATTENUATING INFLAMMATION AND OXIDATIVE STRESS AFTER EXPERIMENTAL SPINAL CORD TRAUMA IN RATS La Rosa G, Cardali S, Genovese T, Conti A, Di Paola R, La Torre D, Cacciola F, Cuzzocrea S.. J Neurosurg Spine. 2004 Oct;1(3):311-21. I.F. 1,403

224. INHIBITORS OF POLY(ADP-RIBOSE) POLYMERASE MODULATE SIGNAL TRANSDUCTION PATHWAYS AND SECONDARY DAMAGE IN EXPERIMENTAL SPINAL CORD TRAUMA.Genovese T, Mazzon E, Muià C, Patel NS, Threadgill MD, Bramanti P, De Sarro A, Thiemermann C, Cuzzocrea S. J Pharmacol Exp Ther. 2005 Feb;312(2):449-57. I.F. 4,309.

225. PREVENTION OF CARRAGEENAN-INDUCED PLEURISY IN MICE BY ANTI-CD30 LIGAND MONOCLONAL ANTIBODY Di Paola R, Di Marco R, Mazzon E, Genovese T, Bendtzen K, Macrì B, Nicoletti F, Cuzzocrea S.. Clin Immunol. 2004 Oct;113(1):64-73. I.F. 3,606

226. WY 14643, A POTENT EXOGENOUS PPAR-ALPHA LIGAND, REDUCES INTESTINAL INJURY ASSOCIATED WITH SPLANCHNIC ARTERY OCCLUSION SHOCK.Cuzzocrea S, Di Paola R, Mazzon E, Genovese T, Muià C, Caputi AP. Shock. 2004 Oct;22(4):340-6. I.F. 3,394

227. EFFECT OF ANTHOCYANINS CONTAINED IN A BLACKBERRY EXTRACT ON THE CIRCULATORY FAILURE AND MULTIPLE ORGAN DYSFUNCTION CAUSED BY ENDOTOXIN IN THE RAT.

Sautebin L, Rossi A, Serraino I, Dugo P, Di Paola R, Mondello L, Genovese T, Britti D, Peli A, Dugo G, Caputi AP, Cuzzocrea S. Planta Med. 2004 Aug;70(8):745-52. I.F. 1,960

228. 15D-PROSTAGLANDIN J2 REDUCES MULTIPLE ORGAN FAILURE CAUSED BY WALL-FRAGMENT OF GRAM-POSITIVE AND GRAM-NEGATIVE BACTERIA.Dugo L, Collin M, Cuzzocrea S, Thiemermann C. Eur J Pharmacol. 2004 Sep 13;498(1-3):295-301. I.F. 2,787

229. EXPRESSION OF ANGIOGENIC FACTORS DURING ACUTE CORONARY SYNDROMES IN HUMAN TYPE 2 DIABETES Marfella R, Esposito K, Nappo F, Siniscalchi M, Sasso FC, Portoghese M, Di Marino MP, Baldi A, Cuzzocrea S, Di Filippo C, Barboso G, Baldi F, Rossi F, D'Amico M, Giugliano D.. Diabetes. 2004 Sep;53(9):2383-91 I.F. 8,398

230. REDUCTION OF THE MULTIPLE ORGAN INJURY AND DYSFUNCTION CAUSED BY ENDOTOXEMIA IN 5-LIPOXYGENASE KNOCKOUT MICE AND BY THE 5-LIPOXYGENASE INHIBITOR ZILEUTON.Collin M, Rossi A, Cuzzocrea S, Patel NS, Di Paola R, Hadley J, Collino M, Sautebin L, Thiemermann C. J Leukoc Biol. 2004 Nov;76(5):961-70. I.F. 4,605

231. PRETREATMENT WITH EPO REDUCES THE INJURY AND DYSFUNCTION CAUSED BY ISCHEMIA/REPERFUSION IN THE MOUSE KIDNEY IN VIVO. Patel NS, Sharples EJ, Cuzzocrea S, Chatterjee PK, Britti D, Yaqoob MM, Thiemermann C. Kidney Int. 2004 Sep;66(3):983-9. I.F. 6,418

232. M40403 PREVENTS MYOCARDIAL INJURY INDUCED BY ACUTE HYPERGLYCAEMIA IN PERFUSED RAT HEART. Di Filippo C, Cuzzocrea S, Marfella R, Fabbroni V, Scollo G, Berrino L, Giugliano D, Rossi F, D'Amico M. Eur J Pharmacol. 2004 Aug 16;497(1):65-74. I.F. 2,787

233. REDUCTION IN THE DEVELOPMENT OF CERULEIN-INDUCED ACUTE PANCREATITIS BY TREATMENT WITH M40401, A NEW SELECTIVE SUPEROXIDE DISMUTASE MIMETIC. Cuzzocrea S, Genovese T, Mazzon E, Di Paola R, Muià C, Britti D, Salvemini D. Shock. 2004 Sep;22(3):254-61. I.F. 3,394

234. GLUCOCORTICOID-INDUCED TNF RECEPTOR FAMILY GENE (GITR) KNOCKOUT MICE EXHIBIT A RESISTANCE TO SPLANCHNIC ARTERY OCCLUSION (SAO) SHOCK. Cuzzocrea S, Nocentini G, Di Paola R, Mazzon E, Ronchetti S, Genovese T, Muià C, Caputi AP, Riccardi C. J Leukoc Biol. 2004 Nov;76(5):933-40. I.F. 4,605

235. ERYTHROPOIETIN REDUCES THE DEVELOPMENT OF EXPERIMENTAL INFLAMMATORY BOWEL DISEASE

Cuzzocrea S, Mazzon E, Di Paola R, Patel NS, Genovese T, Muià C, De Sarro A, Thiemermann C.. J Pharmacol Exp Ther. 2004 Dec;311(3):1272-80. I.F. 4,309

236. REDUCTION OF RENAL ISCHEMIA-REPERFUSION INJURY IN 5-LIPOXYGENASE KNOCKOUT MICE AND BY THE 5-LIPOXYGENASE INHIBITOR ZILEUTON Patel NS, Cuzzocrea S, Chatterjee PK, Di Paola R, Sautebin L, Britti D, Thiemermann C.. Mol Pharmacol. 2004 Aug;66(2):220-7. I.F. 4,711

237. INHIBITION OF POLY(ADP-RIBOSE) POLYMERASE PREVENTS ALLERGEN-INDUCED ASTHMA-LIKE REACTION IN SENSITIZED GUINEA PIGS Suzuki Y, Masini E, Mazzocca C, Cuzzocrea S, Ciampa A, Suzuki H, Bani D.. J Pharmacol Exp Ther. 2004 Dec;311(3):1241-8. I.F. 4,309

238. SUPEROXIDE-RELATED SIGNALING CASCADE MEDIATES NUCLEAR FACTOR-KAPPAB ACTIVATION IN ACUTE INFLAMMATION. Cuzzocrea S, Pisano B, Dugo L, Ianaro A, Ndengele M, Salvemini D. Antioxid Redox Signal. 2004 Aug;6(4):699-704. I.F. 6,190

239. ROLE OF 5-LIPOXYGENASE IN THE MULTIPLE ORGAN FAILURE INDUCED BY ZYMOSAN Cuzzocrea S, Rossi A, Serraino I, Di Paola R, Dugo L, Genovese T, Britti D, Sciarra G, De Sarro A, Caputi AP, Sautebin L.. Intensive Care Med. 2004 Oct;30(10):1935-43. Epub 2004 Jul 6. I.F. 5,055

240. METHYLGUANIDINE REDUCES THE DEVELOPMENT OF NON SEPTIC SHOCK INDUCED BY ZYMOSAN IN MICE. Marzocco S, Di Paola R, Genovese T, Sorrentino R, Britti D, Scollo G, Pinto A, Cuzzocrea S, Autore G. Life Sci. 2004 Aug 6;75(12):1417-33. I.F. 2,583

241. TREATMENT WITH A NOVEL POLY(ADP-RIBOSE) GLYCOHYDROLASE INHIBITOR REDUCES DEVELOPMENT OF SEPTIC SHOCK-LIKE SYNDROME INDUCED BY ZYMOSAN IN MICE Genovese T, Di Paola R, Catalano P, Li JH, Xu W, Massuda E, Caputi AP, Zhang J, Cuzzocrea S.. Crit Care Med. 2004 Jun;32(6):1365-74 I.F. 6,594

242. HIGH-DENSITY LIPOPROTEINS REDUCE THE INTESTINAL DAMAGE ASSOCIATED WITH ISCHEMIA/REPERFUSION AND COLITIS Cuzzocrea S, Dugo L, Patel NS, Di Paola R, Cockerill GW, Genovese T, Thiemermann C.. Shock. 2004 Apr;21(4):342-51. I.F. 3,394

243. BENEFICIAL EFFECTS OF 5-AMINOISOQUINOLINONE, A NOVEL, POTENT, WATER-SOLUBLE, INHIBITOR OF POLY (ADP-RIBOSE) POLYMERASE, IN A RAT MODEL OF SPLANCHNIC ARTERY OCCLUSION AND REPERFUSION.Di Paola R, Genovese T, Caputi AP, Threadgill M, Thiemermann C, Cuzzocrea S. Eur J Pharmacol. 2004 May 25;492(2-3):203-10. I.F. 2,787

244. CALPAIN I INHIBITOR AMELIORATES THE INDICES OF DISEASE SEVERITY IN A MURINE MODEL OF CERULEIN-INDUCED ACUTE PANCREATITIS Virlos I, Mazzon E, Serraino I, Genovese T, Di Paola R, Thiemerman C, Siriwardena A, Cuzzocrea S.. Intensive Care Med. 2004 Aug;30(8):1645-51. I.F. 5,055

245. POTENTIAL THERAPEUTIC EFFECT OF ANTIOXIDANT THERAPY IN SHOCK AND INFLAMMATION Cuzzocrea S, Thiemermann C, Salvemini D.. Curr Med Chem. 2004 May;11(9):1147-62. Review. I.F. 4,823

246. EFFECT OF AMINOGUANIDINE IN LIGATURE-INDUCED PERIODONTITIS IN RATS.Di Paola R, Marzocco S, Mazzon E, Dattola F, Rotondo F, Britti D, De Majo M, Genovese T, Cuzzocrea S. J Dent Res. 2004 Apr;83(4):343-8. I.F. 3,142

247. A PROTECTIVE EFFECT OF THE SYNTHETIC COUMARINE DERIVATIVE CLORICROMENE AGAINST DNB-COLITIS IN THE RAT. Fries W, Mazzon E, Sturiale S, Giofré MR, Lo Presti MA, Cuzzocrea S, Campo GM, Caputi AP, Longo G, Sturniolo GC. Life Sci. 2004 Apr 16;74(22):2749-56. I.F. 2,583

248. MELATONIN PREVENTS LIPOPOLYSACCHARIDE-INDUCED HYPOREACTIVITY IN RAT.d'Emmanuele di Villa Bianca R, Marzocco S, Di Paola R, Autore G, Pinto A, Cuzzocrea S, Sorrentino R. J Pineal Res. 2004 Apr;36(3):146-54. I.F. 5,056

249. A NEWLY IDENTIFIED ROLE FOR SUPEROXIDE IN INFLAMMATORY PAIN.Wang ZQ, Porreca F, Cuzzocrea S, Galen K, Lightfoot R, Masini E, Muscoli C, Mollace V, Ndengele M, Ischiropoulos H, Salvemini D. J Pharmacol Exp Ther. 2004 Jun;309(3):869-78. I.F. 4,309

250. ROSIGLITAZONE, A LIGAND OF THE PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR-GAMMA, REDUCES ACUTE PANCREATITIS INDUCED BY CERULEIN. Cuzzocrea S, Pisano B, Dugo L, Ianaro A, Britti D, Patel NS, Di Paola R, Genovese T, Di Rosa M, Caputi AP, Thiemermann C. Intensive Care Med. 2004 May;30(5):951-6. I.F. 5,055

251. HYPERBARIC OXYGEN THERAPY PREVENTS VASCULAR DERANGEMENT DURING ZYMOSAN-INDUCED MULTIPLE-ORGAN-FAILURE SYNDROME. Imperatore F, Cuzzocrea S, Luongo C, Liguori G, Scafuro A, De Angelis A, Rossi F, Caputi AP, Filippelli A. Intensive Care Med. 2004 Jun;30(6):1175-81. I.F. 5,055.

252. THE CYCLOPENTENONE PROSTAGLANDIN 15-DEOXY-DELTA(12,14)-PROSTAGLANDIN J2 AMELIORATES ISCHEMIC ACUTE RENAL FAILURE Chatterjee PK, Patel NS, Cuzzocrea S, Brown PA, Stewart KN, Mota-Filipe H, Britti D,

Eberhardt W, Pfeilschifter J, Thiemermann C.. Cardiovasc Res. 2004 Feb 15;61(3):630-43. I.F. 5,947

253. EFFECTS OF GW274150, A NOVEL AND SELECTIVE INHIBITOR OF INOS ACTIVITY, IN ACUTE LUNG INFLAMMATION. Dugo L, Marzocco S, Mazzon E, Di Paola R, Genovese T, Caputi AP, Cuzzocrea S. Br J Pharmacol. 2004 Mar;141(6):979-87. I.F. 4,902

254. ROSIGLITAZONE, A LIGAND OF THE PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR-GAMMA, REDUCES THE DEVELOPMENT OF NONSEPTIC SHOCK INDUCED BY ZYMOSAN IN MICE Cuzzocrea S, Pisano B, Dugo L, Ianaro A, Patel NS, Di Paola R, Genovese T, Chatterjee PK, Fulia F, Cuzzocrea E, Di Rosa M, Caputi AP, Thiemermann C.. Crit Care Med. 2004 Feb;32(2):457-66. I.F. 6,594

255. EUK-134 REDUCES RENAL DYSFUNCTION AND INJURY CAUSED BY OXIDATIVE AND NITROSATIVE STRESS OF THE KIDNEY. Chatterjee PK, Patel NS, Kvale EO, Brown PA, Stewart KN, Mota-Filipe H, Sharpe MA, Di Paola R, Cuzzocrea S, Thiemermann C. Am J Nephrol. 2004 Mar-Apr;24(2):165-77. I.F. 3,164

256. ABSENCE OF INDUCIBLE NITRIC OXIDE SYNTHASE REDUCES MYOCARDIAL DAMAGE DURING ISCHEMIA REPERFUSION IN STREPTOZOTOCIN-INDUCED HYPERGLYCEMIC MICE. Marfella R, Di Filippo C, Esposito K, Nappo F, Piegari E, Cuzzocrea S, Berrino L, Rossi F, Giugliano D, D'Amico M. Diabetes. 2004 Feb;53(2):454-62. I.F. 8,398

257. EFFECT OF METHYLGUANIDINE IN CARRAGEENAN-INDUCED ACUTE INFLAMMATION IN THE RATS. Marzocco S, Di Paola R, Serraino I, Sorrentino R, Meli R, Mattaceraso G, Cuzzocrea S, Pinto A, Autore G. Eur J Pharmacol. 2004 Jan 26;484(2-3):341-50. I.F. 2,787

258. SUPEROXIDE: A KEY PLAYER IN HYPERTENSION Cuzzocrea S, Mazzon E, Dugo L, Di Paola R, Caputi AP, Salvemini D.. FASEB J. 2004 Jan;18(1):94-101. I.F. 7,049

259. THREADGILL MD, THIEMERMANN C. 5-AMINOISOQUINOLINONE REDUCES RENAL INJURY AND DYSFUNCTION CAUSED BY EXPERIMENTAL ISCHEMIA/REPERFUSION.Chatterjee PK, Chatterjee BE, Pedersen H, Sivarajah A, McDonald MC, Mota-Filipe H, Brown PA, Stewart KN, Cuzzocrea S, Kidney Int. 2004 Feb;65(2):499-509. I.F. 6,418

260. ROSIGLITAZONE, A LIGAND OF THE PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR-GAMMA, REDUCES ACUTE INFLAMMATION.

Cuzzocrea S, Pisano B, Dugo L, Ianaro A, Maffia P, Patel NS, Di Paola R, Ialenti A, Genovese T, Chatterjee PK, Di Rosa M, Caputi AP, Thiemermann C. Eur J Pharmacol. 2004 Jan 1;483(1):79-93. I.F. 2,787

261. PROTECTIVE EFFECTS OF M40401, A SELECTIVE SUPEROXIDE DISMUTASE MIMETIC, ON ZYMOSAN-INDUCED NONSEPTIC SHOCK Cuzzocrea S, Mazzon E, Di Paola R, Genovese T, Serraino I, Dugo L, Cuzzocrea E, Fulia F, Caputi AP, Salvemini D.. Crit Care Med. 2004 Jan;32(1):157-67. I.F. 6,594

262. CALPAIN INHIBITOR I REDUCES INTESTINAL ISCHEMIA-REPERFUSION INJURY IN THE RAT Marzocco S, Di Paola R, Autore G, Mazzon E, Pinto A, Caputi AP, Thiemermann C, Cuzzocrea S.. Shock. 2004 Jan;21(1):38-44. I.F. 3,394

263. REDUCTION IN THE EVOLUTION OF MURINE TYPE II COLLAGEN-INDUCED ARTHRITIS BY TREATMENT WITH ROSIGLITAZONE, A LIGAND OF THE PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR GAMMA.Cuzzocrea S, Mazzon E, Dugo L, Patel NS, Serraino I, Di Paola R, Genovese T, Britti D, De Maio M, Caputi AP, Thiemermann C. Arthritis Rheum. 2003 Dec;48(12):3544-56. I.F. 6,787

264. EMERGING BIOTHERAPIES FOR INFLAMMATORY BOWEL DISEASE Cuzzocrea S.. Expert Opin Emerg Drugs. 2003 Nov;8(2):339-47. Review. I.F. 3,394

265. PYRROLIDINE DITHIOCARBAMATE REDUCES RENAL DYSFUNCTION AND INJURY CAUSED BY ISCHEMIA/REPERFUSION OF THE RAT KIDNEY. Chatterjee PK, di Villa Bianca RD, Sivarajah A, McDonald MC, Cuzzocrea S, Thiemermann C. Eur J Pharmacol. 2003 Dec 15;482(1-3):271-80. I.F. 2,787

266. RECONSTITUTED HIGH-DENSITY LIPOPROTEIN ATTENUATES ORGAN INJURY AND ADHESION MOLECULE EXPRESSION IN A RODENT MODEL OF ENDOTOXIC SHOCK. McDonald MC, Dhadly P, Cockerill GW, Cuzzocrea S, Mota-Filipe H, Hinds CJ, Miller NE, Thiemermann C. Shock. 2003 Dec;20(6):551-7. I.F. 3,394

267. CUZZOCREA S. PYRROLIDINE DITHIOCARBAMATE REDUCES THE SEVERITY OF CERULEIN-INDUCED MURINE ACUTE PANCREATITIS. Virlos I, Mazzon E, Serraino I, Di Paola R, Genovese T, Britti D, Thiemerman C, Siriwardena A, Shock. 2003 Dec;20(6):544-50. I.F. 3,394

268. PROTECTIVE EFFECTS OF ANTHOCYANINS FROM BLACKBERRY IN A RAT MODEL OF ACUTE LUNG INFLAMMATION Rossi A, Serraino I, Dugo P, Di Paola R, Mondello L, Genovese T, Morabito D, Dugo G, Sautebin L, Caputi AP, Cuzzocrea S.. Free Radic Res. 2003 Aug;37(8):891-900. I.F. 2,826

269. 2-CYCLOPENTEN-1-ONE AND PROSTAGLANDIN J2 REDUCE RESTENOSIS AFTER BALLOON ANGIOPLASTY IN RATS: ROLE OF NF-KAPPAB.Ianaro A, Maffia P, Cuzzocrea S, Mazzon E, Santoro MG, Di Rosa M, Ialenti A. FEBS Lett. 2003 Oct 9;553(1-2):21-7. I.F. 3,264

270. THE TYROSINE KINASE INHIBITOR TYRPHOSTIN AG126 REDUCES RENAL ISCHEMIA/REPERFUSION INJURY IN THE RAT.Chatterjee PK, Patel NS, Kvale EO, Brown PA, Stewart KN, Britti D, Cuzzocrea S, Mota-Filipe H, Thiemermann C. Kidney Int. 2003 Nov;64(5):1605-19. I.F. 6,418

271. ON THE SELECTIVITY OF SUPEROXIDE DISMUTASE MIMETICS AND ITS IMPORTANCE IN PHARMACOLOGICAL STUDIES Muscoli C, Cuzzocrea S, Riley DP, Zweier JL, Thiemermann C, Wang ZQ, Salvemini D.. Br J Pharmacol. 2003 Oct;140(3):445-60. Review. I.F. 4,902

272. DEFICIENCY OF NADPH OXIDASE COMPONENTS P47PHOX AND GP91PHOX CAUSED GRANULOMATOUS SYNOVITIS AND INCREASED CONNECTIVE TISSUE DESTRUCTION IN EXPERIMENTAL ARTHRITIS MODELS van de Loo FA, Bennink MB, Arntz OJ, Smeets RL, Lubberts E, Joosten LA, van Lent PL, Coenen-de Roo CJ, Cuzzocrea S, Segal BH, Holland SM, van den Berg WB.. Am J Pathol. 2003 Oct;163(4):1525-37. I.F. 3,394

273. ROSIGLITAZONE AND 15-DEOXY-DELTA12,14-PROSTAGLANDIN J2, LIGANDS OF THE PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR-GAMMA (PPAR-GAMMA), REDUCE ISCHAEMIA/REPERFUSION INJURY OF THE GUT Cuzzocrea S, Pisano B, Dugo L, Ianaro A, Patel NS, Di Paola R, Genovese T,Chatterjee PK, Di Rosa M, Caputi AP, Thiemermann C.. Br J Pharmacol. 2003 Sep;140(2):366-76. I.F. 4,902.

274. TYRPHOSTIN REDUCES THE ORGAN INJURY IN HAEMORRHAGIC SHOCK: ROLE OF INDUCIBLE NITRIC OXIDE SYNTHASE McDonald M, Abdelrahman M, Cuzzocrea S, Thiemermann C.. Resuscitation. 2003 Sep;58(3):349-61. I.F. 2,513

275. 5-LIPOXYGENASE KNOCKOUT MICE EXHIBIT A RESISTANCE TO ACUTE PANCREATITIS INDUCED BY CERULEIN. Cuzzocrea S, Rossi A, Serraino I, Di Paola R, Dugo L, Genovese T, Britti D, Sciarra G, De Sarro A, Caputi AP, Sautebin L. Immunology. 2003 Sep;110(1):120-30. I.F. 3,432

276. 5-LIPOXYGENASE KNOCKOUT MICE EXHIBIT A RESISTANCE TO SPLANCHNIC ARTERY OCCLUSION SHOCK. Cuzzocrea S, Rossi A, Serraino I, Di Paola R, Dugo L, Genovese T, Caputi AP, Sautebin L. Shock. 2003 Sep;20(3):230-6. I.F. 3,394

277. PYRROLIDINE DITHIOCARBAMATE ATTENUATES THE DEVELOPMENT OF ORGAN FAILURE INDUCED BY ZYMOSAN IN MICE. Cuzzocrea S, Rossi A, Pisano B, Di Paola R, Genovese T, Patel NS, Cuzzocrea E, Ianaro A, Sautebin L, Fulia F, Chatterjee PK, Caputi AP, Thiemermann C. Intensive Care Med. 2003 Nov;29(11):2016-25. I.F. 5,055

278. AGONISTS OF PEROXISOME-PROLIFERATOR ACTIVATED RECEPTOR-GAMMA REDUCE RENAL ISCHEMIA/REPERFUSION INJURY Sivarajah A, Chatterjee PK, Patel NS, Todorovic Z, Hattori Y, Brown PA, Stewart KN, Mota-Filipe H, Cuzzocrea S, Thiemermann C.. Am J Nephrol. 2003 Jul-Aug;23(4):267-76. I.F. 3,164

279. ROLE OF INOS IN HEPATOCYTE TIGHT JUNCTION ALTERATION IN MOUSE MODEL OF EXPERIMENTAL COLITIS Mazzon E, Cuzzocrea S.. Cell Mol Biol (Noisy-le-grand). 2003 Feb;49(1):45-57. I.F. 1,333

280. HIGH DENSITY LIPOPROTEIN (HDL) REDUCES RENAL ISCHEMIA/REPERFUSION INJURY Thiemermann C, Patel NS, Kvale EO, Cockerill GW, Brown PA, Stewart KN, Cuzzocrea S, Britti D, Mota-Filipe H, Chatterjee PK.. J Am Soc Nephrol. 2003 Jul;14(7):1833-43. I.F. 7,505

281. PROTECTIVE EFFECTS OF CYANIDIN-3-O-GLUCOSIDE FROM BLACKBERRY EXTRACT AGAINST PEROXYNITRITE-INDUCED ENDOTHELIAL DYSFUNCTION AND VASCULAR FAILURE Serraino I, Dugo L, Dugo P, Mondello L, Mazzon E, Dugo G, Caputi AP, Cuzzocrea S.. Life Sci. 2003 Jul 18;73(9):1097-114. I.F. 2,583

282. 5-LIPOXYGENASE KNOCKOUT MICE EXHIBIT A RESISTANCE TO PLEURISY AND LUNG INJURY CAUSED BY CARRAGEENAN Cuzzocrea S, Rossi A, Serraino I, Mazzon E, Di Paola R, Dugo L, Genovese T, Calabrò B, Caputi AP, Sautebin L.. J Leukoc Biol. 2003 Jun;73(6):739-46. I.F. 4,605

283. : ROLES OF NITRIC OXIDE AND SUPEROXIDE IN INFLAMMATION.Salvemini D, Ischiropoulos H, Cuzzocrea S. Methods Mol Biol. 2003;225:291-303. Review.

284. EFFECTS OF THE SOD MIMETIC, M40403, ON PROSTAGLANDIN PRODUCTION IN AN IN VIVO MODEL OF ISCHEMIA AND REPERFUSION IN RAT HEART.Marzocca C, Vannacci A, Cuzzocrea S, Salvemini D, Mannaioni PF, Masini E. Inflamm Res. 2003 Apr;52 Suppl 1:S23-4. I.F. 1,457

285. A NONPEPTIDYL MIMIC OF SUPEROXIDE DISMUTASE, M40403, INHIBITS DOSE-LIMITING HYPOTENSION ASSOCIATED WITH INTERLEUKIN-2 AND INCREASES ITS ANTITUMOR EFFECTS Samlowski WE, Petersen R, Cuzzocrea S, Macarthur H, Burton D, McGregor JR, Salvemini D.. Nat Med. 2003 Jun;9(6):750-5. I.F. 27,553

286. COPPER INDUCES TYPE II NITRIC OXIDE SYNTHASE IN VIVO.Cuzzocrea S, Persichini T, Dugo L, Colasanti M, Musci G. Free Radic Biol Med. 2003 May 15;34(10):1253-62. I.F. 5,399

287. A SUPEROXIDE DISMUTASE MIMETIC WITH CATALASE ACTIVITY (EUK-8) REDUCES THE ORGAN INJURY IN ENDOTOXIC SHOCK McDonald MC, d'Emmanuele di Villa Bianca R, Wayman NS, Pinto A, Sharpe MA, Cuzzocrea S, Chatterjee PK, Thiemermann C.. Eur J Pharmacol. 2003 Apr 11;466(1-2):181-9. I.F. 2,787

288. GW274150, A POTENT AND HIGHLY SELECTIVE INHIBITOR OF INOS, REDUCES EXPERIMENTAL RENAL ISCHEMIA/REPERFUSION INJURY Chatterjee PK, Patel NS, Sivarajah A, Kvale EO, Dugo L, Cuzzocrea S, Brown PA, Stewart KN, Mota-Filipe H, Britti D, Yaqoob MM, Thiemermann C.. Kidney Int. 2003 Mar;63(3):853-65. I.F. 6,418

289. EFFECTS OF CLORICROMENE, A COUMARIN DERIVATIVE, ON ENDOTOXIN-INDUCED UVEITIS IN LEWIS RATS Bucolo C, Cuzzocrea S, Mazzon E, Caputi AP.. Invest Ophthalmol Vis Sci. 2003 Mar;44(3):1178-84. I.F. 3,583

290. THE CYCLOPENTENONE PROSTAGLANDIN 15-DEOXY-DELTA(12,14)- PGJ2 ATTENUATES THE DEVELOPMENT OF COLON INJURY CAUSED BY DINITROBENZENE SULPHONIC ACID IN THE RAT.Cuzzocrea S, Ianaro A, Wayman NS, Mazzon E, Pisano B, Dugo L, Serraino I, Di Paola R, Chatterjee PK, Di Rosa M, Caputi AP, Thiemermann C. Br J Pharmacol. 2003 Feb;138(4):678-88. I.F. 4,902

291. INDUCIBLE NITRIC OXIDE SYNTHASE MEDIATES BONE LOSS IN OVARIECTOMIZED MICE Cuzzocrea S, Mazzon E, Dugo L, Genovese T, Di Paola R, Ruggeri Z, Vegeto E, Caputi AP, Van De Loo FA, Puzzolo D, Maggi A.. Endocrinology. 2003 Mar;144(3):1098-107. I.F. 4,945

292. THERAPEUTIC POTENTIAL OF SUPEROXIDE DISMUTASE MIMETICS AS THERAPEUTIC AGENTS IN CRITICAL CARE MEDICINE. Salvemini D, Cuzzocrea S. Crit Care Med. 2003 Jan;31(1 Suppl):S29-38. Review. I.F. 6,594

293. A NOVEL, POTENT AND SELECTIVE INHIBITOR OF THE ACTIVITY OF INDUCIBLE NITRIC OXIDE SYNTHASE (GW274150) REDUCES THE ORGAN INJURY IN HEMORRHAGIC SHOCK McDonald MC, Izumi M, Cuzzocrea S, Thiemermann C.. J Physiol Pharmacol. 2002 Dec;53(4Pt 1):555-69. I.F. 3,394

294. REGULATION OF PROSTAGLANDIN GENERATION IN CARRAGEENAN-INDUCED PLEURISY BY INDUCIBLE NITRIC OXIDE SYNTHASE IN KNOCKOUT MICE. Rossi A, Cuzzocrea S, Mazzon E, Serraino I, De Sarro A, Dugo L, Felice MR, Van de Loo FA, Di Rosa M, Musci G, Caputi AP, Sautebin L. Life Sci. 2003 Jan 24;72(10):1199-208. I.F. 2,583

295. TEMPONE REDUCES RENAL DYSFUNCTION AND INJURY MEDIATED BY OXIDATIVE STRESS OF THE RAT KIDNEY Patel NS, Chatterjee PK, Chatterjee BE, Cuzzocrea S, Serraino I, Brown PA, Stewart KN, Mota-Filipe H, Thiemermann C.. Free Radic Biol Med. 2002 Dec 1;33(11):1575-89. I.F. 5,399

296. THE NOVEL PARP INHIBITOR 5-AMINOISOQUINOLINONE REDUCES THE LIVER INJURY CAUSED BY ISCHEMIA AND REPERFUSION IN THE RAT. Mota-Filipe H, Sepodes B, McDonald MC, Cuzzocrea S, Pinto R, Thiemermann C. Med Sci Monit. 2002 Nov;8(11):BR444-53. I.F. 1,514

297. ROLE OF TIGHT JUNCTION DERANGEMENT IN THE ENDOTHELIAL DYSFUNCTION ELICITED BY EXOGENOUS AND ENDOGENOUS PEROXYNITRITE AND POLY(ADP-RIBOSE) SYNTHETASE.Mazzon E, De Sarro A, Caputi AP, Cuzzocrea S. Shock. 2002 Nov;18(5):434-9. I.F. 3,394

298. SUPEROXIDE DISMUTASE MIMETICS Salvemini D, Muscoli C, Riley DP, Cuzzocrea S.. Pulm Pharmacol Ther. 2002;15(5):439-47. Review. I.F. 2,283

299. OXIDATIVE STRESS IN SEPTIC SHOCK AND DISSEMINATED INTRAVASCULAR COAGULATION.Salvemini D, Cuzzocrea S. Free Radic Biol Med. 2002 Nov 1;33(9):1173-85. Review. I.F. 5,399

300. EFFECTS OF CALPAIN INHIBITOR I ON MULTIPLE ORGAN FAILURE INDUCED BY ZYMOSAN IN THE RAT. Cuzzocrea S, Chatterjee PK, Mazzon E, Serraino I, Dugo L, Centorrino T, Barbera A, Ciccolo A, Fulia F, McDonald MC, Caputi AP, Thiemermann C. Crit Care Med. 2002 Oct;30(10):2284-94. I.F. 6,594

301. ROLE OF IL-10 IN HEPATOCYTE TIGHT JUNCTION ALTERATION IN MOUSE MODEL OF EXPERIMENTAL COLITIS Mazzon E, Puzzolo D, Caputi AP, Cuzzocrea S.. Mol Med. 2002 Jul;8(7):353-66. I.F. 3,411

302. BENEFICIAL EFFECTS OF GW274150, A NOVEL, POTENT AND SELECTIVE INHIBITOR OF INOS ACTIVITY, IN A RODENT MODEL OF COLLAGEN-INDUCED ARTHRITIS. Cuzzocrea S, Chatterjee PK, Mazzon E, McDonald MC, Dugo L, Di Paola R, Serraino I, Britti D, Caputi AP, Thiemermann C. Eur J Pharmacol. 2002 Oct 18;453(1):119-29. I.F. 2,787

303. STAPHYLOCOCCUS AUREUS REDUCES RENAL ISCHEMIA/REPERFUSION INJURY.Chatterjee PK, Zacharowski K, Cuzzocrea S, Brown PA, Stewart KN, Mota-Filipe H, Thiemermann C. Lipoteichoic acid from Kidney Int. 2002 Oct;62(4):1249-63. I.F. 6,418

304. ABSENCE OF ENDOGENOUS INTERLEUKIN-10 ENHANCES THE EVOLUTION OF ACUTE LUNG INJURY Cuzzocrea S, Mazzon E, Dugo L, Serraino I, Di Paola R, Genovese T, De Sarro A, Caputi AP.. Eur Cytokine Netw. 2002 Jul-Sep;13(3):285-97. I.F. 2,984

305. A ROLE FOR SUPEROXIDE IN GENTAMICIN-MEDIATED NEPHROPATHY IN RATS.Cuzzocrea S, Mazzon E, Dugo L, Serraino I, Di Paola R, Britti D, De Sarro A, Pierpaoli S, Caputi A, Masini E, Salvemini D. Eur J Pharmacol. 2002 Aug 16;450(1):67-76. I.F. 2,787

306. ROLE OF INDUCED NITRIC OXIDE IN THE INITIATION OF THE INFLAMMATORY RESPONSE AFTER POSTISCHEMIC INJURY Cuzzocrea S, Chatterjee PK, Mazzon E, Dugo L, De Sarro A, Van de Loo FA, Caputi AP, Thiemermann C.. Shock. 2002 Aug;18(2):169-76. I.F. 3,394

307. ABSENCE OF ENDOGENOUS INTERLEUKIN-6 ENHANCES THE INFLAMMATORY RESPONSE DURING ACUTE PANCREATITIS INDUCED BY CERULEIN IN MICE. Cuzzocrea S, Mazzon E, Dugo L, Centorrino T, Ciccolo A, McDonald MC, de Sarro A, Caputi AP, Thiemermann C. Cytokine. 2002 Jun 7;18(5):274-85. I.F. 2,212

308. SUPEROXIDE, SUPEROXIDE DISMUTASE AND ISCHEMIC INJURY. Salvemini D, Cuzzocrea S. Curr Opin Investig Drugs. 2002 Jun;3(6):886-95. Review. I.F. 3,324

309. MODELING AND BIOLOGICAL EVALUATION OF 3,3'-(1,2-ETHANEDIYL)BIS[2-(4-METHOXYPHENYL)-THIAZOLIDIN-4-ONE], A NEW SYNTHETIC CYCLOOXYGENASE-2 INHIBITOR

Ottaná R, Mazzon E, Dugo L, Monforte F, Maccari R, Sautebin L, De Luca G, Vigorita MG, Alcaro S, Ortuso F, Caputi AP, Cuzzocrea S.. Eur J Pharmacol. 2002 Jul 12;448(1):71-80. I.F. 2,787

310. GPI 6150, A PARP INHIBITOR, REDUCES THE COLON INJURY CAUSED BY DINITROBENZENE SULFONIC ACID IN THE RAT Mazzon E, Dugo L, Li JH, Di Paola R, Genovese T, Caputi AP, Zhang J, Cuzzocrea S.. Biochem Pharmacol. 2002 Jul 15;64(2):327-37. I.F. 4,838

311. SOD MIMETICS ARE COMING OF AGE.Salvemini D, Riley DP, Cuzzocrea S. Nat Rev Drug Discov. 2002 May;1(5):367-74. Review. I.F. 28,690

312. PROTECTIVE EFFECTS OF M40403, A SELECTIVE SUPEROXIDE DISMUTASE MIMETIC, IN MYOCARDIAL ISCHAEMIA AND REPERFUSION INJURY IN VIVO.Masini E, Cuzzocrea S, Mazzon E, Marzocca C, Mannaioni PF, Salvemini D. Br J Pharmacol. 2002 Jul;136(6):905-17. Erratum in: Br J Pharmacol. 2002 Dec;137(8):1387. I.F. 4,902

313. THE TYROSINE KINASE INHIBITOR TYRPHOSTIN AG 126 REDUCES THE MULTIPLE ORGAN FAILURE INDUCED BY ZYMOSAN IN THE RAT. Dugo L, Chatterjee PK, Mazzon E, McDonald MC, Paola RD, Fulia F, Caputi AP, Thiemermann C, Cuzzocrea S. Intensive Care Med. 2002 Jun;28(6):775-88. I.F. 5,055

314. LIGANDS OF THE PEROXISOME PROLIFERATOR-ACTIVATED RECEPTORS (PPAR-GAMMA AND PPAR-ALPHA) REDUCE MYOCARDIAL INFARCT SIZE Wayman NS, Hattori Y, McDonald MC, Mota-Filipe H, Cuzzocrea S, Pisano B, Chatterjee PK, Thiemermann C.. FASEB J. 2002 Jul;16(9):1027-40. I.F. 7,049

315. INDUCIBLE NITRIC OXIDE SYNTHASE-DEFICIENT MICE EXHIBIT RESISTANCE TO THE ACUTE PANCREATITIS INDUCED BY CERULEIN. Cuzzocrea S, Mazzon E, Dugo L, Serraino I, Centorrino T, Ciccolo A, Van de Loo FA, Britti D, Caputi AP, Thiemermann C. Shock. 2002 May;17(5):416-22. I.F. 3,394

316. PROTECTIVE EFFECTS OF CELECOXIB ON LUNG INJURY AND RED BLOOD CELLS MODIFICATION INDUCED BY CARRAGEENAN IN THE RAT Cuzzocrea S, Mazzon E, Sautebin L, Dugo L, Serraino I, De Sarro A, Caputi AP.. Biochem Pharmacol. 2002 Feb 15;63(4):785-95. I.F. 4,838

317. THE CYCLOPENTENONE PROSTAGLANDIN 15-DEOXY-DELTA(12,14)-PROSTAGLANDIN J(2) ATTENUATES THE DEVELOPMENT OF ACUTE AND CHRONIC INFLAMMATION.Cuzzocrea S, Wayman NS, Mazzon E, Dugo L, Di Paola R, Serraino I, Britti D, Chatterjee PK, Caputi AP, Thiemermann C. Mol Pharmacol. 2002 May;61(5):997-1007. I.F. 4,711

318. BENEFICIAL EFFECTS OF GPI 6150, AN INHIBITOR OF POLY(ADP-RIBOSE) POLYMERASE IN A RAT MODEL OF SPLANCHNIC ARTERY OCCLUSION AND REPERFUSION. Mazzon E, Dugo L, De SA, Li JH, Caputi AP, Zhang J, Cuzzocrea S. Shock. 2002 Mar;17(3):222-7. I.F. 3,394

319. PHARMACOLOGICAL ACTIONS OF MELATONIN IN ACUTE AND CHRONIC INFLAMMATION. Cuzzocrea S, Reiter RJ. Curr Top Med Chem. 2002 Feb;2(2):153-65. Review. I.F. 4,268

320. INHIBITION OF INDUCIBLE NITRIC OXIDE SYNTHASE REDUCES RENAL ISCHEMIA/REPERFUSION INJURY Chatterjee PK, Patel NS, Kvale EO, Cuzzocrea S, Brown PA, Stewart KN, Mota-Filipe H, Thiemermann C.. Kidney Int. 2002 Mar;61(3):862-71. I.F. 6,418

321. MELATONIN REDUCES OXIDATIVE DAMAGE AND INCREASES SURVIVAL OF MICE INFECTED WITH SCHISTOSOMA MANSONI El-Sokkary GH, Omar HM, Hassanein AF, Cuzzocrea S, Reiter RJ.. Free Radic Biol Med. 2002 Feb 15;32(4):319-32. I.F. 5,399

322. EFFECTS OF 5-AMINOISOQUINOLINONE, A WATER-SOLUBLE, POTENT INHIBITOR OF THE ACTIVITY OF POLY (ADP-RIBOSE) POLYMERASE, IN A RODENT MODEL OF LUNG INJURY Cuzzocrea S, McDonald MC, Mazzon E, Dugo L, Serraino I, Threadgill M, Caputi AP, Thiemermann C.. Biochem Pharmacol. 2002 Jan 15;63(2):293-304. I.F. 4,838

323. PYRROLIDINE DITHIOCARBAMATE ATTENUATES THE DEVELOPMENT OF ACUTE AND CHRONIC INFLAMMATION Cuzzocrea S, Chatterjee PK, Mazzon E, Dugo L, Serraino I, Britti D, Mazzullo G, Caputi AP, Thiemermann C.. Br J Pharmacol. 2002 Jan;135(2):496-510. I.F. 4,902

324. ABSENCE OF ENDOGENEOUS INTERLEUKIN-10 ENHANCES THE EVOLUTION OF MURINE TYPE-II COLLAGEN-INDUCED ARTHRITIS.Cuzzocrea S, Mazzon E, Dugo L, Serraino I, Britti D, De Maio M, Caputi AP. Eur Cytokine Netw. 2001 Oct-Dec;12(4):568-80. I.F. 2,984

325. AMELIORATION OF JOINT DISEASE IN A RAT MODEL OF COLLAGEN-INDUCED ARTHRITIS BY M40403, A SUPEROXIDE DISMUTASE MIMETIC Salvemini D, Mazzon E, Dugo L, Serraino I, De Sarro A, Caputi AP, Cuzzocrea S.. Arthritis Rheum. 2001 Dec;44(12):2909-21. I.F. 6,787

326. PROTECTIVE EFFECTS OF M40403, A SUPEROXIDE DISMUTASE MIMETIC, IN A RODENT MODEL OF COLITIS.Cuzzocrea S, Mazzon E, Dugo L, Caputi AP, Riley DP, Salvemini D. Eur J Pharmacol. 2001 Nov 30;432(1):79-89. I.F. 2,787

327. EFFECTS OF MELATONIN TREATMENT IN SEPTIC NEWBORNS. Gitto E, Karbownik M, Reiter RJ, Tan DX, Cuzzocrea S, Chiurazzi P, Cordaro S, Corona G, Trimarchi G, Barberi I. Pediatr Res. 2001 Dec;50(6):756-60. I.F. 2,604

328. CELECOXIB, A SELECTIVE CYCLO-OXYGENASE-2 INHIBITOR REDUCES THE SEVERITY OF EXPERIMENTAL COLITIS INDUCED BY DINITROBENZENE SULFONIC ACID IN RATS. Cuzzocrea S, Mazzon E, Serraino I, Dugo L, Centorrino T, Ciccolo A, Sautebin L, Caputi AP. Eur J Pharmacol. 2001 Nov 9;431(1):91-102. I.F. 2,787

329. INCREASED LEVELS OF MALONDIALDEHYDE AND NITRITE/NITRATE IN THE BLOOD OF ASPHYXIATED NEWBORNS: REDUCTION BY MELATONIN Fulia F, Gitto E, Cuzzocrea S, Reiter RJ, Dugo L, Gitto P, Barberi S, Cordaro S, Barberi I.. J Pineal Res. 2001 Nov;31(4):343-9. I.F. 5,056

330. INDIVIDUAL AND SYNERGISTIC ANTIOXIDATIVE ACTIONS OF MELATONIN: STUDIES WITH VITAMIN E, VITAMIN C, GLUTATHIONE AND DESFERRIOXAMINE (DESFEROXAMINE) IN RAT LIVER HOMOGENATES.Gitto E, Tan DX, Reiter RJ, Karbownik M, Manchester LC, Cuzzocrea S, Fulia F, Barberi I. J Pharm Pharmacol. 2001 Oct;53(10):1393-401. I.F. 1,847

331. THE PROTECTIVE ROLE OF ENDOGENOUS ESTROGENS IN CARRAGEENAN-INDUCED LUNG INJURY IN THE RAT.Cuzzocrea S, Mazzon E, Sautebin L, Serraino I, Dugo L, Calabró G, Caputi AP, Maggi A. Mol Med. 2001 Jul;7(7):478-87. I.F. 3,411

332. HIGH DENSITY LIPOPROTEINS REDUCE ORGAN INJURY AND ORGAN DYSFUNCTION IN A RAT MODEL OF HEMORRHAGIC SHOCK Cockerill GW, McDonald MC, Mota-Filipe H, Cuzzocrea S, Miller NE, Thiemermann C.. FASEB J. 2001 Sep;15(11):1941-52. I.F. 7,049

333. PHARMACOLOGICAL ACTION OF MELATONIN IN SHOCK, INFLAMMATION AND ISCHEMIA/REPERFUSION INJURY. Cuzzocrea S, Reiter RJ. Eur J Pharmacol. 2001 Aug 24;426(1-2):1-10. Review. I.F. 2,787

334. THE SELECTIVE GUANYLATE CYCLASE INHIBITOR ODQ REDUCES MULTIPLE ORGAN INJURY IN RODENT MODELS OF GRAM-POSITIVE AND GRAM-NEGATIVE SHOCK.Zacharowski K, Berkels R, Olbrich A, Chatterjee PK, Cuzzocrea S, Foster SJ, Thiemermann C. Crit Care Med. 2001 Aug;29(8):1599-608. I.F. 6,594

335. EFFECT OF MELATONIN ON CELLULAR ENERGY DEPLETION MEDIATED BY PEROXYNITRITE AND POLY (ADP-RIBOSE) SYNTHETASE ACTIVATION IN AN ACUTE MODEL OF INFLAMMATION. Dugo L, Serraino I, Fulia F, De Sarro A, Caputi AP, Cuzzocrea S. J Pineal Res. 2001 Aug;31(1):76-84. I.F. 5,056

336. EFFECT OF N-ACETYLCYSTEINE ON GENTAMICIN-MEDIATED NEPHROPATHY IN RATS. Mazzon E, Britti D, De Sarro A, Caputi AP, Cuzzocrea S. Eur J Pharmacol. 2001 Jul 13;424(1):75-83. I.F. 2,787

337. INDUCIBLE NITRIC OXIDE SYNTHASE KNOCKOUT MICE EXHIBIT RESISTANCE TO THE MULTIPLE ORGAN FAILURE INDUCED BY ZYMOSAN Cuzzocrea S, Mazzon E, Dugo L, Barbera A, Centorrino T, Ciccolo A, Fonti MT, Caputi AP.. Shock. 2001 Jul;16(1):51-8. I.F. 3,394

338. CALPAIN INHIBITOR-1 REDUCES RENAL ISCHEMIA/REPERFUSION INJURY IN THE RAT.Chatterjee PK, Brown PA, Cuzzocrea S, Zacharowski K, Stewart KN, Mota-Filipe H, McDonald MC, Thiemermann C. Kidney Int. 2001 Jun;59(6):2073-83. I.F. 6,418

339. PROTECTIVE EFFECTS OF N-ACETYLCYSTEINE ON LUNG INJURY AND RED BLOOD CELL MODIFICATION INDUCED BY CARRAGEENAN IN THE RAT Cuzzocrea S, Mazzon E, Dugo L, Serraino I, Ciccolo A, Centorrino T, De Sarro A, Caputi AP.. FASEB J. 2001 May;15(7):1187-200. I.F. 7,049

340. CALPAIN INHIBITOR I REDUCES COLON INJURY CAUSED BY DINITROBENZENE SULPHONIC ACID IN THE RAT Cuzzocrea S, McDonald MC, Mazzon E, Mota-Filipe H, Centorrino T, Terranova ML, Ciccolo A, Britti D, Caputi AP, Thiemermann C.. Gut. 2001 Apr;48(4):478-88. I.F. 9,766

341. GPI 6150, A POLY (ADP-RIBOSE) POLYMERASE INHIBITOR, EXHIBITS AN ANTI-INFLAMMATORY EFFECT IN RAT MODELS OF INFLAMMATION Mazzon E, Serraino I, Li JH, Dugo L, Caputi AP, Zhang J, Cuzzocrea S.. Eur J Pharmacol. 2001 Mar 9;415(1):85-94. I.F. 2,787

342. PHARMACOLOGICAL MANIPULATION OF THE INFLAMMATORY CASCADE BY THE SUPEROXIDE DISMUTASE MIMETIC, M40403Salvemini D, Mazzon E, Dugo L, Riley DP, Serraino I, Caputi AP, Cuzzocrea S.. Br J Pharmacol. 2001 Feb;132(4):815-27. I.F. 4,902

343. THE STABLE NITROXIDE, TEMPOL, ATTENUATES THE EFFECTS OF PEROXYNITRITE AND OXYGEN-DERIVED FREE RADICALS. Thiemermann C, McDonald MC, Cuzzocrea S. Crit Care Med. 2001 Jan;29(1):223-4. I.F. 6,594

344. BENEFICIAL EFFECTS OF TEMPOL, A MEMBRANE-PERMEABLE RADICAL SCAVENGER, ON THE MULTIPLE ORGAN FAILURE INDUCED BY ZYMOSAN IN THE RAT. Cuzzocrea S, McDonald MC, Mazzon E, Filipe HM, Centorrino T, Lepore V, Terranova ML, Ciccolo A, Caputi AP, Thiemermann C. Crit Care Med. 2001 Jan;29(1):102-11. I.F. 6,594

345. ANTIOXIDANT THERAPY: A NEW PHARMACOLOGICAL APPROACH IN SHOCK, INFLAMMATION, AND ISCHEMIA/REPERFUSION INJURY. Cuzzocrea S, Riley DP, Caputi AP, Salvemini D. Pharmacol Rev. 2001 Mar;53(1):135-59. Review. I.F. 21,936

346. MELATONIN REDUCES DINITROBENZENE SULFONIC ACID-INDUCED COLITIS. Cuzzocrea S, Mazzon E, Serraino I, Lepore V, Terranova ML, Ciccolo A, Caputi AP. J Pineal Res. 2001 Jan;30(1):1-12. I.F. 5,056

347. PROTECTIVE EFFECTS OF A NEW STABLE, HIGHLY ACTIVE SOD MIMETIC, M40401 IN SPLANCHNIC ARTERY OCCLUSION AND REPERFUSION Cuzzocrea S, Mazzon E, Dugo L, Caputi AP, Aston K, Riley DP, Salvemini D.. Br J Pharmacol. 2001 Jan;132(1):19-29. I.F. 4,902

348. CALPAIN INHIBITOR I REDUCES THE ACTIVATION OF NUCLEAR FACTOR-KAPPAB AND ORGAN INJURY/DYSFUNCTION IN HEMORRHAGIC SHOCK McDonald MC, Mota-Filipe H, Paul A, Cuzzocrea S, Abdelrahman M, Harwood S, Plevin R, Chatterjee PK, Yaqoob MM, Thiemermann C.. FASEB J. 2001 Jan;15(1):171-186. I.F. 7,049

349. CALPAIN INHIBITOR I REDUCES THE DEVELOPMENT OF ACUTE AND CHRONIC INFLAMMATION.Cuzzocrea S, McDonald MC, Mazzon E, Siriwardena D, Serraino I, Dugo L, Britti D, Mazzullo G, Caputi AP, Thiemermann C. Am J Pathol. 2000 Dec;157(6):2065-79. I.F. 5,697

350. CLORICROMENE, A COUMARINE DERIVATIVE, PROTECTS AGAINST COLLAGEN-INDUCED ARTHRITIS IN LEWIS RATS. Cuzzocrea S, Mazzon E, Bevilaqua C, Costantino G, Britti D, Mazzullo G, De Sarro A, Caputi AP. Br J Pharmacol. 2000 Dec;131(7):1399-407. I.F. 4,902

351. ROLE OF FREE RADICALS AND POLY(ADP-RIBOSE) SYNTHETASE IN INTESTINAL TIGHT JUNCTION PERMEABILITY Cuzzocrea S, Mazzon E, De Sarro A, Caputi AP.. Mol Med. 2000 Sep;6(9):766-78. I.F. 3,411

352. INDUCIBLE NITRIC OXIDE SYNTHASE-KNOCKOUT MICE EXHIBIT RESISTANCE TO PLEURISY AND LUNG INJURY CAUSED BY CARRAGEENAN Cuzzocrea S, Mazzon E, Calabro G, Dugo L, De Sarro A, van De LOO FA, Caputi AP.. Am J Respir Crit Care Med. 2000 Nov;162(5):1859-66. I.F. 3,394

353. PROTECTIVE EFFECTS OF MELATONIN IN ISCHEMIC BRAIN INJURY. Cuzzocrea S, Costantino G, Gitto E, Mazzon E, Fulia F, Serraino I, Cordaro S, Barberi I, De Sarro A, Caputi AP. J Pineal Res. 2000 Nov;29(4):217-27. I.F. 5,056

354. TEMPOL, A MEMBRANE-PERMEABLE RADICAL SCAVENGER, REDUCES DINITROBENZENE SULFONIC ACID-INDUCED COLITIS. Cuzzocrea S, McDonald MC, Mazzon E, Dugo L, Lepore V, Fonti MT, Ciccolo A, Terranova ML, Caputi AP, Thiemermann C. Eur J Pharmacol. 2000 Oct 6;406(1):127-37. I.F. 2,787

355. THE TYROSINE KINASE INHIBITOR TYRPHOSTIN AG 126 REDUCED THE DEVELOPMENT OF COLITIS IN THE RAT Cuzzocrea S, McDonald MC, Mazzon E, Mota-Filipe H, Lepore V, Ciccolo A, Terranova ML, Britti D, Caputi AP, Thiemermann C.. Lab Invest. 2000 Sep;80(9):1439-53. I.F. 4,580

356. EFFECTS OF TEMPOL, A MEMBRANE-PERMEABLE RADICAL SCAVENGER, IN A GERBIL MODEL OF BRAIN INJURY Cuzzocrea S, McDonald MC, Mazzon E, Siriwardena D, Costantino G, Fulia F, Cucinotta G, Gitto E, Cordaro S, Barberi I, De Sarro A, Caputi AP, Thiemermann C.. Brain Res. 2000 Sep 1;875(1-2):96-106. I.F. 2,494

357. EFFECTS OF N-ACETYLCYSTEINE IN A RAT MODEL OF ISCHEMIA AND REPERFUSION INJURY.Cuzzocrea S, Mazzon E, Costantino G, Serraino I, De Sarro A, Caputi AP. Cardiovasc Res. 2000 Aug 18;47(3):537-48. I.F. 5,947

358. BENEFICIAL EFFECTS OF TEMPOL, A MEMBRANE-PERMEABLE RADICAL SCAVENGER, IN A RODENT MODEL OF SPLANCHNIC ARTERY OCCLUSION AND REPERFUSION.Cuzzocrea S, McDonald MC, Mazzon E, Filipe HM, Costantino G, Caputi AP, Thiemermann C. Shock. 2000 Aug;14(2):150-6. I.F. 3,394

359. TEMPOL, A MEMBRANE-PERMEABLE RADICAL SCAVENGER, REDUCES OXIDANT STRESS-MEDIATED RENAL DYSFUNCTION AND INJURY IN THE RAT. Chatterjee PK, Cuzzocrea S, Brown PA, Zacharowski K, Stewart KN, Mota-Filipe H, Thiemermann C. Kidney Int. 2000 Aug;58(2):658-73. I.F. 6,418

360. BENEFICIAL EFFECTS OF N-ACETYLCYSTEINE ON ISCHAEMIC BRAIN INJURY.Cuzzocrea S, Mazzon E, Costantino G, Serraino I, Dugo L, Calabrò G, Cucinotta G, De Sarro A, Caputi AP. Br J Pharmacol. 2000 Jul;130(6):1219-26. I.F. 4,902

361. MEMBRANE-PERMEABLE RADICAL SCAVENGER, TEMPOL, REDUCES MULTIPLE ORGAN INJURY IN A RODENT MODEL OF GRAM-POSITIVE SHOCK.Zacharowski K, Olbrich A, Cuzzocrea S, Foster SJ, Thiemermann C. Crit Care Med. 2000 Jun;28(6):1953-61. I.F. 6,594

362. THE TYROSINE KINASE INHIBITOR TYRPHOSTIN AG126 REDUCES THE DEVELOPMENT OF ACUTE AND CHRONIC INFLAMMATION Cuzzocrea S, McDonald MC, Mazzon E, Siriwardena D, Calabrò G, Britti D, Mazzullo G, De Sarro A, Caputi AP, Thiemermann C.. Am J Pathol. 2000 Jul;157(1):145-58. I.F. 5,697

363. LIPOTEICHOIC ACID INDUCES DELAYED PROTECTION IN THE RAT HEART: A COMPARISON WITH ENDOTOXIN Zacharowski K, Frank S, Otto M, Chatterjee PK, Cuzzocrea S, Hafner G, Pfeilschifter J, Thiemermann C.. Arterioscler Thromb Vasc Biol. 2000 Jun;20(6):1521-8. I.F. 6,858

364. BENEFICIAL EFFECTS OF PEROXYNITRITE DECOMPOSITION CATALYST IN A RAT MODEL OF SPLANCHNIC ARTERY OCCLUSION AND REPERFUSION Cuzzocrea S, Misko TP, Costantino G, Mazzon E, Micali A, Caputi AP, Macarthur H, Salvemini D.. FASEB J. 2000 Jun;14(9):1061-72. I.F. 7,049

365. 17BETA-ESTRADIOL ANTIINFLAMMATORY ACTIVITY IN CARRAGEENAN-INDUCED PLEURISY. Cuzzocrea S, Santagati S, Sautebin L, Mazzon E, Calabrò G, Serraino I, Caputi AP, Maggi A. Endocrinology. 2000 Apr;141(4):1455-63. I.F. 4,945

366. INHIBITORS OF POLY (ADP-RIBOSE) SYNTHETASE REDUCE RENAL ISCHEMIA-REPERFUSION INJURY IN THE ANESTHETIZED RAT IN VIVO.Chatterjee PK, Zacharowski K, Cuzzocrea S, Otto M, Thiemermann C. FASEB J. 2000 Apr;14(5):641-51. I.F. 7,049

367. ROLE OF HYPERBARIC OXYGEN EXPOSURE IN REDUCTION OF LIPID PEROXIDATION AND IN MULTIPLE ORGAN FAILURE INDUCED BY ZYMOSAN ADMINISTRATION IN THE RAT.Cuzzocrea S, Imperatore F, Costantino G, Luongo C, Mazzon E, Scafuro MA, Mangoni G, Caputi AP, Rossi F, Filippelli A. Shock. 2000 Mar;13(3):197-203. I.F. 3,394

368. EFFECTS OF TEMPOL, A MEMBRANE-PERMEABLE RADICAL SCAVENGER, IN A RODENT MODEL OF CARRAGEENAN-INDUCED PLEURISY.Cuzzocrea S, McDonald MC, Filipe HM, Costantino G, Mazzon E, Santagati S, Caputi AP, Thiemermann C. Eur J Pharmacol. 2000 Feb 25;390(1-2):209-22. I.F. 2,787

369. BENEFICIAL EFFECTS OF TEMPOL, A MEMBRANE-PERMEABLE RADICAL SCAVENGER, IN A RODENT MODEL OF COLLAGEN-INDUCED ARTHRITIS. Cuzzocrea S, McDonald MC, Mota-Filipe H, Mazzon E, Costantino G, Britti D, Mazzullo G, Caputi AP, Thiemermann C. Arthritis Rheum. 2000 Feb;43(2):320-8. I.F. 6,787

370. BENEFICIAL EFFECTS OF MELATONIN IN A RAT MODEL OF SPLANCHNIC ARTERY OCCLUSION AND REPERFUSION

Cuzzocrea S, Costantino G, Mazzon E, Micali A, De Sarro A, Caputi AP.. J Pineal Res. 2000 Jan;28(1):52-63. I.F. 5,056

371. BENEFICIAL EFFECTS OF MN(III)TETRAKIS (4-BENZOIC ACID) PORPHYRIN (MNTBAP), A SUPEROXIDE DISMUTASE MIMETIC, IN ZYMOSAN-INDUCED SHOCK.Cuzzocrea S, Costantino G, Mazzon E, De Sarro A, Caputi AP. Br J Pharmacol. 1999 Nov;128(6):1241-51. I.F. 4,902

372. ROLE OF MELATONIN IN REDUCTION OF LIPID PEROXIDATION AND PEROXYNITRITE FORMATION IN NON-SEPTIC SHOCK INDUCED BY ZYMOSAN.El-Sokkary GH, Reiter RJ, Cuzzocrea S, Caputi AP, Hassanein AF, Tan DX. Shock. 1999 Nov;12(5):402-8. I.F. 3,394

373. THE PROTECTIVE ROLE OF ENDOGENOUS MELATONIN IN CARRAGEENAN-INDUCED PLEURISY IN THE RAT.Cuzzocrea S, Tan DX, Costantino G, Mazzon E, Caputi AP, Reiter RJ. FASEB J. 1999 Nov;13(14):1930-8. I.F. 7,049

374. ROLE OF IL-6 IN THE PLEURISY AND LUNG INJURY CAUSED BY CARRAGEENAN.Cuzzocrea S, Sautebin L, De Sarro G, Costantino G, Rombolà L, Mazzon E, Ialenti A, De Sarro A, Ciliberto G, Di Rosa M, Caputi AP, Thiemermann C. J Immunol. 1999 Nov 1;163(9):5094-104. I.F. 6

375. A NONPEPTIDYL MIMIC OF SUPEROXIDE DISMUTASE WITH THERAPEUTIC ACTIVITY IN RATS.Salvemini D, Wang ZQ, Zweier JL, Samouilov A, Macarthur H, Misko TP, Currie MG, Cuzzocrea S, Sikorski JA, Riley DP. Science. 1999 Oct 8;286(5438):304-6. I.F. 28,103

376. A MEMBRANE-PERMEABLE RADICAL SCAVENGER REDUCES THE ORGAN INJURY IN HEMORRHAGIC SHOCK Mota-Filipe H, McDonald MC, Cuzzocrea S, Thiemermann C.. Shock. 1999 Oct;12(4):255-61. I.F. 3,394

377. REGULATION OF PROSTAGLANDIN PRODUCTION BY INHIBITION OF POLY (ADP-RIBOSE) SYNTHASE IN CARRAGEENAN-INDUCED PLEURISY. Cuzzocrea S, Sautebin L, Costantino G, Rombolà L, Mazzon E, Caputi AP. Life Sci. 1999;65(12):1297-304. I.F. 2,583

378. IL-6 KNOCK-OUT MICE EXHIBIT RESISTANCE TO SPLANCHNIC ARTERY OCCLUSION SHOCK. Cuzzocrea S, De Sarro G, Costantino G, Ciliberto G, Mazzon E, De Sarro A, Caputi AP. J Leukoc Biol. 1999 Sep;66(3):471-80. I.F. 4,605

379. TEMPOL REDUCES INFARCT SIZE IN RODENT MODELS OF REGIONAL MYOCARDIAL ISCHEMIA AND REPERFUSION. McDonald MC, Zacharowski K, Bowes J, Cuzzocrea S, Thiemermann C. Free Radic Biol Med. 1999 Sep;27(5-6):493-503. I.F. 5,399

380. PROTECTIVE EFFECT OF N-ACETYLCYSTEINE ON MULTIPLE ORGAN FAILURE INDUCED BY ZYMOSAN IN THE RAT Cuzzocrea S, Costantino G, Mazzon E, Caputi AP.. Crit Care Med. 1999 Aug;27(8):1524-32. I.F. 6,594

381. PROTECTIVE EFFECT OF POLY(ADP-RIBOSE) SYNTHETASE INHIBITION ON MULTIPLE ORGAN FAILURE AFTER ZYMOSAN-INDUCED PERITONITIS IN THE RAT.Cuzzocrea S, Zingarelli B, Costantino G, Sottile A, Teti D, Caputi AP. Crit Care Med. 1999 Aug;27(8):1517-23. I.F. 6,594

382. INHIBITORS OF POLY (ADP-RIBOSE) SYNTHETASE PROTECT RAT PROXIMAL TUBULAR CELLS AGAINST OXIDANT STRESS.Chatterjee PK, Cuzzocrea S, Thiemermann C. Kidney Int. 1999 Sep;56(3):973-84. I.F. 6,418

383. PROTECTIVE EFFECTS OF POLY (ADP-RIBOSE) SYNTHASE INHIBITORS IN ZYMOSAN-ACTIVATED PLASMA INDUCED PAW EDEMA.Cuzzocrea S, Costantino G, Zingarelli B, Caputi AP. Life Sci. 1999;65(9):957-64. I.F. 2,583

384. REGULATION OF PROSTAGLANDIN PRODUCTION IN CARRAGEENAN-INDUCED PLEURISY BY MELATONIN. Cuzzocrea S, Costantino G, Mazzon E, Caputi AP. J Pineal Res. 1999 Aug;27(1):9-14 I.F. 5,056

385. PROTECTIVE EFFECTS OF MN(III)TETRAKIS (4-BENZOIC ACID) PORPHYRIN (MNTBAP), A SUPEROXIDE DISMUTASE MIMETIC, IN PAW OEDEMA INDUCED BY CARRAGEENAN IN THE RAT.Cuzzocrea S, Costantino G, Mazzon E, Zingarelli B, De Sarro A, Caputi AP. Biochem Pharmacol. 1999 Jul 1;58(1):171-6. I.F. 4,838

386. ROLE OF INTERLEUKIN-6 IN A NON-SEPTIC SHOCK MODEL INDUCED BY ZYMOSAN Cuzzocrea S, de Sarro G, Costantino G, Mazzon E, Laurà R, Ciriaco E, de Sarro A, Caputi AP. Eur Cytokine Netw. 1999 Jun;10(2):191-203. I.F. 2,984

387. THE PROTECTIVE ROLE OF ENDOGENOUS GLUTATHIONE IN CARRAGEENAN-INDUCED PLEURISY IN THE RAT

Cuzzocrea S, Costantino G, Zingarelli B, Mazzon E, Micali A, Caputi AP.. Eur J Pharmacol. 1999 May 14;372(2):187-97. I.F. 2,787

388. PROTECTIVE EFFECT OF MELATONIN ON ZYMOSAN-INDUCED CELLULAR DAMAGE.Cuzzocrea S, Caputi AP. Biol Signals Recept. 1999 Jan-Apr;8(1-2):136-42. I.F. 1,114

389. BENEFICIAL EFFECTS OF RAXOFELAST (IRFI 016), A NEW HYDROPHILIC VITAMIN E-LIKE ANTIOXIDANT, IN CARRAGEENAN-INDUCED PLEURISY.Cuzzocrea S, Costantino G, Mazzon E, Caputi AP. Br J Pharmacol. 1999 Jan;126(2):407-14. I.F. 4,902

390. PROTECTIVE EFFECT OF N-ACETYLCYSTEINE ON CELLULAR ENERGY DEPLETION IN A NON-SEPTIC SHOCK MODEL INDUCED BY ZYMOSAN IN THE RAT. Cuzzocrea S, Costantino G, Caputi AP. Shock. 1999 Feb;11(2):143-8. I.F. 3,394

391. BENEFICIAL EFFECTS OF MN(III)TETRAKIS (4-BENZOIC ACID) PORPHYRIN (MNTBAP), A SUPEROXIDE DISMUTASE MIMETIC, IN CARRAGEENAN-INDUCED PLEURISY.Cuzzocrea S, Zingarelli B, Costantino G, Caputi AP. Free Radic Biol Med. 1999 Jan;26(1-2):25-33. I.F. 5,399

392. PROTECTIVE EFFECTS OF MELATONIN IN ZYMOSAN-ACTIVATED PLASMA-INDUCED PAW INFLAMMATION Costantino G, Cuzzocrea S, Mazzon E, Caputi AP.. Eur J Pharmacol. 1998 Dec 11;363(1):57-63. I.F. 2,787

393. EFFECTS OF HYPERBARIC OXYGEN EXPOSURE ON A ZYMOSAN-INDUCED SHOCK MODEL. Luongo C, Imperatore F, Cuzzocrea S, Filippelli A, Scafuro MA, Mangoni G, Portolano F, Rossi F. Crit Care Med. 1998 Dec;26(12):1972-6. I.F. 6,594

394. MERCAPTOETHYLGUANIDINE, A COMBINED INHIBITOR OF NITRIC OXIDE SYNTHASE AND PEROXYNITRITE SCAVENGER, REDUCES TRINITROBENZENE SULFONIC ACID-INDUCED COLONIC DAMAGE IN RATS. Zingarelli B, Cuzzocrea S, Szabó C, Salzman AL. J Pharmacol Exp Ther. 1998 Dec;287(3):1048-55. I.F. 4,309

395. OXIDATION, TYROSINE NITRATION AND CYTOSTASIS INDUCTION IN THE ABSENCE OF INDUCIBLE NITRIC OXIDE SYNTHASE. Zingarelli B, Virág L, Szabó A, Cuzzocrea S, Salzman AL, Szabó C. Int J Mol Med. 1998 May;1(5):787-95. I.F. 1,880

396. PEROXYNITRITE-INDUCED THYMOCYTE APOPTOSIS: THE ROLE OF CASPASES AND POLY (ADP-RIBOSE) SYNTHETASE (PARS) ACTIVATION

Virág L, Scott GS, Cuzzocrea S, Marmer D, Salzman AL, Szabó C.. Immunology. 1998 Jul;94(3):345-55. I.F. 3,432

397. PROTECTIVE EFFECT OF MELATONIN ON CELLULAR ENERGY DEPLETION MEDIATED BY PEROXYNITRITE AND POLY (ADP-RIBOSE) SYNTHETASE ACTIVATION IN A NON-SEPTIC SHOCK MODEL INDUCED BY ZYMOSAN IN THE RAT. Cuzzocrea S, Costantino G, Caputi AP. J Pineal Res. 1998 Sep;25(2):78-85. I.F. 5,056

398. ROLE OF PEROXYNITRITE AND POLY (ADP-RIBOSYL) SYNTHETASE ACTIVATION IN CARDIOVASCULAR DERANGEMENT INDUCED BY ZYMOSAN IN THE RAT. Cuzzocrea S, Zingarelli B, Caputi AP. Life Sci. 1998;63(11):923-33. I.F. 2,583

399. ROLE OF CONSTITUTIVE NITRIC OXIDE SYNTHASE AND PEROXYNITRITE PRODUCTION IN A RAT MODEL OF SPLANCHNIC ARTERY OCCLUSION SHOCK.Cuzzocrea S, Zingarelli B, Caputi AP. Life Sci. 1998;63(9):789-99. I.F. 2,583

400. PROTECTIVE EFFECT OF MELATONIN IN A NON-SEPTIC SHOCK MODEL INDUCED BY ZYMOSAN IN THE RAT Cuzzocrea S, Zingarelli B, Costantino G, Caputi AP.. J Pineal Res. 1998 Aug;25(1):24-33. I.F. 5,056

401. EVIDENCE FOR IN VIVO PEROXYNITRITE PRODUCTION IN HUMAN CHRONIC HEPATITIS.Cuzzocrea S, Zingarelli B, Villari D, Caputi AP, Longo G. Life Sci. 1998;63(2):PL25-30. I.F. 2,583

402. PEROXYNITRATE-MEDIATED DNA STRAND BREAKAGE ACTIVATES POLY(ADP-RIBOSE) SYNTHETASE AND CAUSES CELLULAR ENERGY DEPLETION IN A NONSEPTIC SHOCK MODEL INDUCED BY ZYMOSAN IN THE RAT Cuzzocrea S, Zingarelli B, Caputi AP.. Shock. 1998 May;9(5):336-40. I.F. 3,394

403. ROLE OF PEROXYNITRITE AND POLY (ADP-RIBOSE) SYNTHETASE ON CELLULAR ENERGY DEPLETION IN CARRAGEENAN-INDUCED PLEURISY Cuzzocrea S, Zingarelli B, Caputi AP.. J Chemother. 1998 Apr;10(2):153-6. I.F. 0,843

404. PROTECTION AGAINST PEROXYNITRITE-INDUCED FIBROBLAST INJURY AND ARTHRITIS DEVELOPMENT BY INHIBITION OF POLY(ADP-RIBOSE) SYNTHASE. Szabó C, Virág L, Cuzzocrea S, Scott GS, Hake P, O'Connor MP, Zingarelli B, Salzman A, Kun E. Proc Natl Acad Sci U S A. 1998 Mar 31;95(7):3867-72. I.F. 9,380

405. PROTECTIVE EFFECTS OF 3-AMINOBENZAMIDE, AN INHIBITOR OF POLY (ADP-RIBOSE) SYNTHASE IN A CARRAGEENAN-INDUCED MODEL OF LOCAL INFLAMMATION.Cuzzocrea S, Zingarelli B, Gilad E, Hake P, Salzman AL, Szabó C. Eur J Pharmacol. 1998 Jan 19;342(1):67-76. I.F. 2,787

406. PEROXYNITRITE-MEDIATED DNA STRAND BREAKAGE ACTIVATES POLY (ADP-RIBOSE) SYNTHETASE AND CAUSES CELLULAR ENERGY DEPLETION IN CARRAGEENAN-INDUCED PLEURISY Cuzzocrea S, Caputi AP, Zingarelli B.. Immunology. 1998 Jan;93(1):96-101. I.F. 3,432

407. EFFECT OF L-BUTHIONINE-(S,R)-SULPHOXIMINE, AN INHIBITOR OF GAMMA-GLUTAMYLCYSTEINE SYNTHETASE ON PEROXYNITRITE- AND ENDOTOXIC SHOCK-INDUCED VASCULAR FAILURE Cuzzocrea S, Zingarelli B, O'Connor M, Salzman AL, Szabó C.. Br J Pharmacol. 1998 Feb;123(3):525-37. I.F. 4,902

408. PROTECTION AGAINST MYOCARDIAL ISCHEMIA AND REPERFUSION INJURY BY 3-AMINOBENZAMIDE, AN INHIBITOR OF POLY (ADP-RIBOSE) SYNTHETASE. Zingarelli B, Cuzzocrea S, Zsengellér Z, Salzman AL, Szabó C. Cardiovasc Res. 1997 Nov;36(2):205-15. I.F. 5,947

409. ANTIINFLAMMATORY EFFECTS OF MERCAPTOETHYLGUANIDINE, A COMBINED INHIBITOR OF NITRIC OXIDE SYNTHASE AND PEROXYNITRITE SCAVENGER, IN CARRAGEENAN-INDUCED MODELS OF INFLAMMATION Cuzzocrea S, Zingarelli B, Hake P, Salzman AL, Szabó C.. Free Radic Biol Med. 1998 Feb;24(3):450-9. I.F. 5,399

410. LODOXAMIDE VERSUS SPAGLUMIC ACID: A COMPARATIVE DOUBLE-BLIND TRIAL ON PATIENTS SUFFERING FROM SEASONAL ALLERGIC CONJUNCTIVITIS INDUCED BY PARIETARIA POLLEN Purello D'Ambrosio F, Gangemi S, Ricciardi L, Cuzzocrea S, Di Lorenzo G.. Allergol (Madr). 1997 Sep-Oct;25(5):233-7.

411. PROTECTIVE EFFECT OF MELATONIN IN CARRAGEENAN-INDUCED MODELS OF LOCAL INFLAMMATION: RELATIONSHIP TO ITS INHIBITORY EFFECT ON NITRIC OXIDE PRODUCTION AND ITS PEROXYNITRITE SCAVENGING ACTIVITY Cuzzocrea S, Zingarelli B, Gilad E, Hake P, Salzman AL, Szabó C.. J Pineal Res. 1997 Sep;23(2):106-16. I.F. 5,056

412. LIPOCORTIN 1 PROTECTS AGAINST SPLANCHNIC ARTERY OCCLUSION AND REPERFUSION INJURY BY AFFECTING NEUTROPHIL MIGRATION. Cuzzocrea S, Tailor A, Zingarelli B, Salzman AL, Flower RJ, Szabó C, Perretti M. J Immunol. 1997 Nov 15;159(10):5089-97. I.F. 6

413. ROLE OF PEROXYNITRITE AND ACTIVATION OF POLY (ADP-RIBOSE) SYNTHASE IN THE VASCULAR FAILURE INDUCED BY ZYMOSAN-ACTIVATED PLASMA. Cuzzocrea S, Zingarelli B, O'Connor M, Salzman AL, Caputi AP, Szabó C. Br J Pharmacol. 1997 Oct;122(3):493-503. I.F. 4,902

414. MULTIPLE ORGAN FAILURE FOLLOWING ZYMOSAN-INDUCED PERITONITIS IS MEDIATED BY NITRIC OXIDE Cuzzocrea S, Zingarelli B, Sautebin L, Rizzo A, Crisafulli C, Campo GM, Costantino G, Calapai G, Nava F, Di Rosa M, Caputi AP.. Shock. 1997 Oct;8(4):268-75. I.F. 3,394

415. INHIBITION OF POLY (ADP-RIBOSE) SYNTHETASE ATTENUATES NEUTROPHIL RECRUITMENT AND EXERTS ANTIINFLAMMATORY EFFECTS Szabó C, Lim LH, Cuzzocrea S, Getting SJ, Zingarelli B, Flower RJ, Salzman AL, Perretti M.. J Exp Med. 1997 Oct 6;186(7):1041-9. I.F. 15,219

416. INHIBITION OF NITRIC OXIDE SYNTHASE WITH PYRAZOLE-1-CARBOXAMIDINE AND RELATED COMPOUNDS Southan GJ, Gauld D, Lubeskie A, Zingarelli B, Cuzzocrea S, Salzman AL, Szabó C, Wolff DJ.. Biochem Pharmacol. 1997 Aug 1;54(3):409-17. I.F. 4,838

417. ENDOTHELIAL DYSFUNCTION IN A RAT MODEL OF ENDOTOXIC SHOCK. IMPORTANCE OF THE ACTIVATION OF POLY (ADP-RIBOSE) SYNTHETASE BY PEROXYNITRITE.Szabó C, Cuzzocrea S, Zingarelli B, O'Connor M, Salzman AL. J Clin Invest. 1997 Aug 1;100(3):723-35. I.F. 16,559

418. MELATONIN EFFECTS ON INHIBITION OF THIRST AND FEVER INDUCED BY LIPOPOLYSACCHARIDE IN RAT. Nava F, Calapai G, Facciolà G, Cuzzocrea S, Giuliani G, De Sarro A, Caputi AP. Eur J Pharmacol. 1997 Jul 23;331(2-3):267-74 I.F. 2,787

419. ETHYLENE OXIDE ALLERGY IN DIALYSIS PATIENTS. Purello D'Ambrosio F, Savica V, Gangemi S, Ricciardi L, Bagnato GF, Santoro D, Cuzzocrea S, Bellinghieri G. Nephrol Dial Transplant. 1997 Jul;12(7):1461-3. I.F. 3,568

420. BENEFICIAL EFFECTS OF 3-AMINOBENZAMIDE, AN INHIBITOR OF POLY (ADP-RIBOSE) SYNTHETASE IN A RAT MODEL OF SPLANCHNIC ARTERY OCCLUSION AND REPERFUSION Cuzzocrea S, Zingarelli B, Costantino G, Szabó A, Salzman AL, Caputi AP, Szabó C.. Br J Pharmacol. 1997 Jul;121(6):1065-74. I.F. 4,902

421. ROLE OF NITRIC OXIDE IN A NONSEPTIC SHOCK MODEL INDUCED BY ZYMOSAN IN THE RAT.

Cuzzocrea S, Filippelli A, Zingarelli B, Falciani M, Caputi AP, Rossi F. Shock. 1997 May;7(5):351-7. I.F. 3,394

422. EFFECTS OF INTERLEUKIN-10 ON WATER INTAKE, LOCOMOTORY ACTIVITY, AND RECTAL TEMPERATURE IN RAT TREATED WITH ENDOTOXIN Nava F, Calapai G, Facciolá G, Cuzzocrea S, Marciano MC, De Sarro A, Caputi AP.. Int J Immunopharmacol. 1997 Jan;19(1):31-8. I.F. 1,053

423. MELATONIN IS A SCAVENGER OF PEROXYNITRITE.Gilad E, Cuzzocrea S, Zingarelli B, Salzman AL, Szabó C. Life Sci. 1997;60(10):PL169-74. I.F. 2,583

424. ZYMOSAN-ACTIVATED PLASMA INDUCES PAW OEDEMA BY NITRIC OXIDE AND PROSTAGLANDIN PRODUCTION Cuzzocrea S, Zingarelli B, Calapai G, Nava F, Caputi AP. Life Sci. 1997;60(3):215-20. I.F. 2,583

425. INHIBITION OF NITRIC OXIDE FORMATION REDUCES VOLUNTARY ETHANOL CONSUMPTION IN THE RAT Calapai G, Mazzaglia G, Sautebin L, Costantino G, Marciano MC, Cuzzocrea S, Di Rosa M, Caputi AP. Psychopharmacology (Berl). 1996 Jun;125(4):398-401. I.F. 3,676

LAVORI IN CORSO DI STAMPA

1. Cantarella G, Di Benedetto G, Scollo M, Paterniti I, Cuzzocrea S, Bosco P, Nocentini G, Riccardi C, Bernardini R. Neutralization of Tumor Necrosis Factor-Related Apoptosis-Inducing Ligand Reduces Spinal Cord Injury Damage in Mice. Neuropsychopharmacology. 2010 Jan 27. [Epub ahead of print]

2. Cuzzocrea S, Malleo G, Genovese T, Mazzon E, Esposito E, Muià C, Abdelrahman M, Di Paola R, Thiemermann C. Effects of glycogen synthase kinase-3beta inhibition on the development of cerulein-induced acute pancreatitis in mice*. Crit Care Med. 2007 Oct 16. [Epub ahead of print]

3. Crisafulli C, Cuzzocrea S. THE ROLE ENDOGENOUS AND EXOGENOUS LIGANDS FOR THE PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR ALPHA (PPAR-alpha) IN THE REGULATION OF INFLAMMATION IN MACROPHAGES. Shock. 2008 Oct 23. [Epub ahead of print]

4. Mondello S, Mazzon E, Paola RD, Crisafulli C, Mondello P, Buemi M, Aloisi C, Cuzzocrea S. Thalidomide suppresses sclerosing encapsulating peritonitis in rats experimental model. Shock. 2008 Dec 22. [Epub ahead of print]

5. Di Paola R, Melani A, Esposito E, Mazzon E, Paterniti I, Bramanti P, Pedata F, Cuzzocrea S. ADENOSINE A2A RECEPTOR SELECTIVE STIMULATION REDUCES SIGNALING PATHWAYS INVOLVED IN THE DEVELOPMENT OF INTESTINE ISCHEMIA AND REPERFUSION INJURY. Shock. 2009 Nov 17. [Epub ahead of print]

LAVORI IN ESTENSO SU LIBRI IN INGLESE

1) ROLE OF NITRIC OXIDE ON MULTIPLE ORGAN FAILURE INDUCED BY ZYMOSAN. S. Cuzzocrea, B. Zingarelli, L. Sautebin, M. Di Rosa, A. P. Caputi The Immune Consequences of Trauma, Shock and Sepsi. Mechanism and Therapeutic Approaches; Monduzzi editore s.p.a. Bologna, Italia; pag. 995-999, 1997.

2) ROLE OF POLY-ADP RIBOYLTRANSFERASE IN SPLANCHNIC ARTERY OCCLUSION SHOCK IN THE RAT. S. Cuzzocrea, B. Zingarelli, A.L. Salzman, and C. Szabó. The Immune Consequences of Trauma, Shock and Sepsi. Mechanism and Therapeutic Approaches; Monduzzi editore s.p.a. Bologna, Italia; pag. 243-246, 1997.

3) POLY (ADP-RIBOSE) SYNTHETASE ACTIVATION INDUCED BY PEROXYNITRITE MEDIATES MYOCARDIAL ISCHEMIA AND REPERFUSION INJURY. B. Zingarelli, S. Cuzzocrea, M. O’Connor, Z. Zsengeller, A.L. Salzman, and C. Szabó. The Immune Consequences of Trauma, Shock and Sepsi. Mechanism and Therapeutic Approaches; Monduzzi editore s.p.a. Bologna, Italia; pag. 681-685, 1997.

4) ROLE OF POLY (ADP-RIBOSE) SYNTHETASE (PARS) IN THE PEROXYNITRITE AND NITRIC OXIDE-INDUCED CYTOTOXICITY: STUDIES IN A PARS KNOCKOUT FIBROBLAS CELL LINE. C. Szabó, L. Viràg, B. Zingarelli, G.S. Scott, S. Cuzzocrea, M. O’Connor, A.L. Salzman.In “Biology of Nitric Oxide” (Eds Moncada S., Stamler J., Gross S., Higgs E.A.) Portland Press, Londra, U.K.; pag.265, 1998.

5) NITRIC OXIDE AND PEROXYNITRITE RELATED ANTIINFLAMMATORY EFFECTS OF MELATONINC. Szabó, E. Gilard, S. Cuzzocrea, P. Hake, B. Zingarelli, A.L. Salzman.In “Biology of Nitric Oxide” (Eds Moncada S., Stamler J., Gross S., Higgs E.A.) Portland Press, Londra, U.K.; pag.269, 1998.

6) ANTIINFLAMMATORY EFFECTS OF MERCAPTOETHYLGUANIDINE, AN INHIBITOR OF THE INDUCIBLE NITRIC OXIDE SYNTHASE AND A SCAVENGER OF PEROXYNITRITE.C. Szabó, S. Cuzzocrea, P. Hake, B. Zingarelli, A.L. Salzman.In “Biology of Nitric Oxide” (Eds Moncada S., Stamler J., Gross S., Higgs E.A.) Portland Press, Londra, U.K.; pag.284, 1998.

7) ROLE OF PEROXYNITRITE AND POLY (ADP-RIBOSE) SYNTHETASE (PARS) ACTIVATION EXPERIMENTAL COLITISA.L. Salzman, B. Zingarelli, S. Cuzzocrea, C. Szabó.In “Biology of Nitric Oxide” (Eds Moncada S., Stamler J., Gross S., Higgs E.A.) Portland Press, Londra, U.K.; pag.42, 1998.

8) POLY (ADP-RIBOSE) SYNTHETASE MODULATES EXPRESSION OF P-SELECTINE AND ICAM-1 IN MYOCARDIAL ISCHEMIA-REPERFUSION INJURYC. Szabó, B. Zingarelli, S. Cuzzocrea, A.L. Salzman.In “Biology of Nitric Oxide” (Eds Moncada S., Stamler J., Gross S., Higgs E.A.) Portland Press, Londra, U.K.; pag.277, 1998.

9) PROTECTIVE EFFECT OF AN INHIBITOR OF POLY (ADP-RIBOSE) SYNTHETASE IN COLLAGEN-INDUCED ARTHRITIS.C. Szabó, S. Cuzzocrea, P. Hake, G.S. Scott, R. Hirsch, A.L. Salzman.In “Biology of Nitric Oxide” (Eds Moncada S., Stamler J., Gross S., Higgs E.A.) Portland Press, Londra, U.K.; pag.280, 1998.

10) EVIDENCE FOR THE PEROXYNITRITE - POLY (ADP-RIBOSE) SYNTHETASE PATHWAY IN THE PATHOGENESIS OF MESENTERIC ARTERY REPERFUSION INJURYC. Szabó, A. Szabò, S. Cuzzocrea, B. Zingarelli, A.L. Salzman.In “Biology of Nitric Oxide” (Eds Moncada S., Stamler J., Gross S., Higgs E.A.) Portland Press, Londra, U.K.; pag.278, 1998.

11) ROLE OF INTERLEUKIN-6 IN MULTIPLE ORGAN FAILURE INDUCED BY ZYMOSAN.

S. Cuzzocrea, G.B. De Sarro, G. Costantino, A. De Sarro, A.P. Caputi.Haematologica, 83: 15-16, 1998.

12) PEROXYNITRITE: THE DARK SIDE OF NITRIC OXIDE – EFFECTS OF MERCAPTOETHYLGUANIDINE, A COMBINED INHIBITOR OF INDUCIBLE NITRIC OXIDE SYNTHETASE AND SCAVENGER OF PEROXYNITRITE, IN SHOCK, INFLAMMATION, AND ISCHEMIA-REPERFUSION INJURY.C. Szabó, T. Csont, A. Szabò, B. Zingarelli, S. Cuzzocrea, A.L. Salzman and G.J. Southan.In ” Shock, Sepsis, and Organ Failure: Scavenging of Nitric oxide and Inhibition of its Production” (Eds G. Schlag, H. Redl). Springer, 203-246, 1999.

13) EFFECTS OF MELATONIN ON ISCHEMIC BRAIN INJURY S. Cuzzocrea, G. Costantino, E. Gitto, E. Mazzon, F. Fulia, I. Serraino, S. Cordaro, I. Berberi A. De Sarro, A.P. Caputi The Immune Consequences of Trauma, Shock and Sepsi. Mechanism and Therapeutic Approaches; Monduzzi editore s.p.a. Bologna, Italia; pag. 367-372, 2000.

14) EFFECTS OF N-ACETYLCYSTEINE IN ISCHEMIA AND REPERFUSION INJURY S. Cuzzocrea, E. Mazzon, G. Costantino, I. Serraino, A. De Sarro, A.P. CaputiThe Immune Consequences of Trauma, Shock and Sepsi. Mechanism and Therapeutic Approaches; Monduzzi editore s.p.a. Bologna, Italia; pag. 401-406, 2000.

15) EFFECTS OF TEMPOL, A MEMBRANE-PERMEABLE RADICAL SCAVENGER, ON THE MULTIPLE ORGAN FAILURE INDUCED BY ZYMOSAN IN THE RATS. Cuzzocrea, M.C. McDonald, E. Mazzon, H. Mota Filipe, V. Lepore, M.L. Terranova, A. Ciccolo, A.P. Caputi, C. Thiemermann.The Immune Consequences of Trauma, Shock and Sepsi. Mechanism and Therapeutic Approaches; Monduzzi editore s.p.a. Bologna, Italia; pag. 395-400, 2000.

16) INHIBITION OF THE ACTIVATION OF NFkB IN SHOCK M. McDonald, H. Ruetten, H. Mota Filipe, S. Cuzzocrea, C. Thiemermann.The Immune Consequences of Trauma, Shock and Sepsi. Mechanism and Therapeutic Approaches; Monduzzi editore s.p.a. Bologna, Italia; pag. 301-306, 2000.

17) INHIBITION OF THE ACTIVATION OF POLY (ADP-ROBOSE) POLYMERASE IN HEMORRHAGIC SHOCK M.C. McDonald, M. Abdelrahman, H. Mota Filipe, S. Cuzzocrea, C. Thiemermann.The Immune Consequences of Trauma, Shock and Sepsi. Mechanism and Therapeutic Approaches; Monduzzi editore s.p.a. Bologna, Italia; pag. 355-359, 2000.

18) ROLE OF INDUCIBLE NITRIC OXIDE SYNTHETASE IN LOCAL INFLAMMATIONS. Cuzzocrea, L. Sautebin, G. Costantino, G. Calabrò, A. De Sarro, M. Di Rosa, A.P. Caputi.In “Biology of Nitric Oxide” (Eds Moncada S., Stamler J., Gross S., Higgs E.A.) Portland Press, Londra, U.K.; pag. …, 2000.

19) PROTECTIVE EFFECTS OF TEMPOL, A MEMBRANE-PERMEABLE RADICAL SCAVENGER, IN A RAT MODEL OF COLLAGEN-INDUCED ARTHRITISS. Cuzzocrea, M.C. McDonald, G. Costantino, E. Mazzon, D. Britti, A.P. Caputi, C.ThiemermannIn “Biology of Nitric Oxide” (Eds Moncada S., Stamler J., Gross S., Higgs E.A.) Portland Press, Londra, U.K.; pag. …, 2000.

20) BENEFICIAL EFFECTS OF N-ACETYLCYSTEINE ON ISCHEMIC BRAIN INJURY S. Cuzzocrea, G. Costantino, E. Mazzon, A. De Sarro, A.P. Caputi In “Biology of Nitric Oxide” (Eds Moncada S., Stamler J., Gross S., Higgs E.A.) Portland Press, Londra, U.K.; pag. …, 2000.

21) ROLE OF NITRIC OXIDE AND REACTIVE OXYGEN SPECIES IN ARTHRITISS. CuzzocreaNitric Oxide and Inflammation (Eds D. Salvemini & T.R. Billiard) BioScience Switzerland pag 145-160, 2001.

22) ROLE OF NITRIC OXIDE AND REACTIVE OXYGEN SPECIES IN ZYMOSAN-INDUCED SHOCK S. CuzzocreaNitric Oxide, Basic Research and Clinical Applications (Eds RJ Gryglewski & P. Minuz) IOS Press pag 126,136, 2001.

23) ROLE OF NITRIC OXIDE AND PEROXYNITRITE IN NON SEPTIC SHOCK S. CuzzocreaRecent Research Developments in Endocrinology. (Ed Pandalai S.G.) Transworld Research Network Vol 2 Part I pag 55-68, 2001.

24) ROLE OF NITRIC OXIDE AND SUPEROXIDE IN INFLAMMATIOND. Salvemini, H. Ischiropoulos, S. Cuzzocrea. M e t h o d s i n M o l e c u l a r B i o l o g y, Vol. 225: Inflammation Protocols Edited by P.G. Winyard and D.A. Willoughby225: pag- 291-303, 2003

25) ROLE OF ESTROGEN IN INFLAMMATIONS. CuzzocreaRecent Res. Devel. Biochem pag- 101-120, 2005

26) CALPAIN INHIBITOR I REDUCES INTESTINAL ISCHEMIA-REPERFUSION INJURY IN THE RATR. Di Paola S. Marzocco, G. Autore, A. Pinto, A.P. Caputi, C. Thiemmermann, S. CuzzocreaImmune Consequences and Therapy Editor Eugen Faist. Medimond International Proceedings. Monduzzi editore s.p.a. Bologna, Italia; pp:221-224

27) ROSIGLITAZONE, A LIGAND OF THE PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR-GAMMA (PPAR-Γ) REDUCES THE DEVELOPMENT OF NON SEPTIC SHOCK INDUCED BY ZYMOSAN IN MICES. Cuzzocrea, L. Dugo, N.S.A. Patel, R. Di Paola, T. Genovese, P.K. Chatterjee, A.P. Caputi, C. Thiemermann Immune Consequences and Therapy Editor Eugen Faist. Medimond International Proceedings. Monduzzi editore s.p.a. Bologna, Italia; pp:225-230

28) PYRROLIDINE DITHIOCARBAMATE REDUCED SPINAL CORD TRAUMA IN RATS T. Genovese, S. Cardali, A. Conti, R. Di Paola, S. Cuzzocrea.Immune Consequences and Therapy Editor Eugen Faist. Medimond International Proceedings. Monduzzi editore s.p.a. Bologna, Italia; pp: 17-22

29) REDUCTION IN THE DEVELOPMENT OF CERULEIN-INDUCED ACUTE PANCREATITIS BY TREATMENT WITH M40401, A NEW SELECTIVE SUPEROXIDE DISMUTASE MIMETIC. S. Cuzzocrea, T. Genovese, E. Mazzon, R. Di Paola, C. Muià, D. Britti, D. Salvemini11th Congress of the European Shock Society Vienna, Austria January 27-30, 2005Monduzzi editore s.p.a. Bologna, p 61-65; F127R9009

30) BENEFICIAL EFFECTS OF 5-AMINOISOQUINOLINONE, A NOVEL, POTENT, WATER-SOLUBLE, INHIBITOR OF THE OF POLY (ADP-RIBOSE) POLYMERASE, IN A RAT MODEL OF SPLANCHNIC ARTERY OCCLUSION AND REPERFUSIONR. Di Paola, T. Genovese, A.P. Caputi, M. Threadgill, C. Thiemermann, S. Cuzzocrea11th Congress of the European Shock Society Vienna, Austria January 27-30, 2005Monduzzi editore s.p.a. Bologna, p67-70; F127R9010

31) INHIBITORS OF POLY (ADP-RIBOSE) POLYMERASE MODULATE SIGNAL TRANSDUCTION PATHWAYS AND SECONDARY DAMAGE IN EXPERIMENTAL SPINAL CORD TRAUMA. T. Genovese, E. Mazzon, C. Muià, N.S.A. Patel, M.D. Threadgill, P. Bramanti, A. De Sarro, C. Thiemermann, S. Cuzzocrea.11th Congress of the European Shock Society Vienna, Austria January 27-30, 2005Monduzzi editore s.p.a. Bologna, p127-131; F127R9011

32) WY 14643, A POTENT EXOGENOUS PPAR-α LIGAND REDUCES INTESTINAL INJURY ASSOCIATED WITH SPLANCHNIC ARTERY OCCLUSION (SAO) SHOCK.S. Cuzzocrea, R. Di Paola, E. Mazzon, T. Genovese, C. Muià, A.P. Caputi11th Congress of the European Shock Society Vienna, Austria January 27-30, 2005MEDIMOND p 79-83; F127R9013

33) ROSIGLITAZONE AND 15-DEOXY-∆12,14-PROSTAGLANDIN J2, LIGANDS OF THE PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR-γ (PPAR-γ), REDUCE ISCHAEMIA/REPERFUSION INJURY OF THE GUTS. Cuzzocrea, B. Pisano, L. Dugo, A. Ianaro, N.S.A. Patel, R. Di Paola, T. Genovese, P.K. Chatterjee, M. Di Rosa, A.P. Caputi, Christoph Thiemermann11th Congress of the European Shock Society Vienna, Austria January 27-30, 2005Monduzzi editore s.p.a. Bologna, p 71-77; F127R9012

34) ROLE OF ENDOGENOUS AND EXOGENOUS MELATONIN IN INFLAMATIONSalvatore CuzzocreaMelatonin: Biological Basis of its Function in Health and Disease, edited by S.R. Pandi-Perumal and Daniel Cardinali. Cap 11 pag. 127-137, 2006.

35) 17Β-ESTRADIOL ON SECONDARY DAMAGE AFTER SCIS. Cuzzocrea, T. Genovese, E. Mazzon, E. Esposito, R. Di Paola, C. Muià, C. Crisafulli, E. Cuzzocrea, P. Bramanti and I.H. Chaudry7th World Congress on Trauma, Shock, Inflammation and Sepsis Munich, Germany March 13-17, 2007MEDIMOND s.r.l. Bologna, p 45-49; H313C0026 45.

36) GLYCOGEN SYNTHASE KINASE-3ß INHIBITION ATTENUATES THE DEVELOPMENT OF ISCHEMIA/REPERFUSION INJURY OF THE GUTS. Cuzzocrea, E. Mazzon, E. Esposito, C. Muià, M. Abdelrahman, R. Di Paola, C. Crisafulli, P. Bramanti, E. Cuzzocrea and C. Thiemermann7th World Congress on Trauma, Shock, Inflammation and Sepsis Munich, Germany March 13-

17, 2007MEDIMOND s.r.l. Bologna, p 51-54; H313C0025.

37) SPLANCHNIC ISCHEMIA AND REPERFUSION INJURY IS REDUCED BY GENETIC OR PHARMACOLOGICAL INHIBITION OF TNF-aE. Esposito, E. Mazzon, C. Muià, R. Meli, E. Sessa, E. Cuzzocrea and S. Cuzzocrea.7th World Congress on Trauma, Shock, Inflammation and Sepsis Munich, Germany March 13-17, 2007MEDIMOND s.r.l. Bologna, p 63-66; H313C0027.

38) ETANERCEPT ATTENUATES THE DEVELOPMENT OF CERULEIN-INDUCED ACUTE PANCREATITIS IN MICE. A COMPARISON WITH TNF-a GENETIC DELETIONG. Malleo, E. Mazzon, T. Genovese, R. Di Paola, C. Muià, E. Cuzzocrea, A.K. Siriwardena and S. Cuzzocrea.7th World Congress on Trauma, Shock, Inflammation and Sepsis Munich, Germany March 13-17, 2007MEDIMOND s.r.l. Bologna, p 97-101; H313C0028.

COMUNICAZIONI A CONGRESSI

1) ROLE OF NITRIC OXIDE IN A NON SEPTIC MODEL INDUCED BY ZYMOSAN IN THE RAT. S. Cuzzocrea, A. Filippelli, B. Zingarelli, M. Falciani, A.P. Caputi, and F. Rossi. Fundamental & Clinical Pharmacology 10 181 1996. Società Italiana di Farmacologia and French association des Pharmacologites, Capri 23-26 Maggio 1996 Italia.

2) ROLE OF NITRIC OXIDE IN DRINKING AND PRESSOR RESPONSES INDUCED BY ANGIOTENSIN II: EFFECTOR OF WATER DEPRIVATION. G. Calapai, L. Sautebin, F. Nava, MC. Marciano, S. Cuzzocrea, A.P. Caputi. Fundamental & Clinical Pharmacology 10 169 1996. Società Italiana di Farmacologia and French association des Pharmacologites, Capri 23-26 Maggio 1996 Italia.

3) NITRIC OXIDE AND VOLUNTARY ETHANOL CONSUMPTION IN THE RAT. G. Calapai, G. Mazzaglia, L. Sautebin, G. Costantino, S. Cuzzocrea A.P. Caputi. Fundamental & Clinical Pharmacology 10 168 1996. Società Italiana di Farmacologia and French association des Pharmacologites, Capri 23-26 Maggio 1996 Italia.

4) CARDIOVASCULAR DERANGEMENT MEDIATED BY NITRIC OXIDE IN A NON SEPTIC SHOCK MODEL INDUCED BY ZYMOSAN IN THE RAT. S. Cuzzocrea, B. Zingarelli, A. Filippelli, A.P. Caputi, F. Rossi. Nineteenth Annual Conference on Shock, Gran Traverse Village, Michigan USA 2-5 Giugno 1996. Shock 5 (S2): abs. 187, 1996.

5) EFFECT OF HYPERBARIC OXYGEN THERAPY ON ZYMOSAN-INDUCED SHOCK MODEL.C. Luongo, F. Imperatore, S. Cuzzocrea, MA. Scafuro, V. de Novellis, F. Portolano, M. Starace, F. RossiInternational Joint meeting on Hyperbaric and Underwater Medicine, Milano, Italia, 4-8 Settembre 1996, Proceedings 389, 1996.

6) ZYMOSAN-INDUCED SYSTEMIC IFLAMMATION IN THE RAT IS MEDIATED BY NITRIC OXIDE. S. Cuzzocrea, A. Filippelli, B. Zingarelli, M. Falciani, A.P. Caputi, F. Rossi. Atti del Congresso. II International Paraelios Symposium Nitric Oxide and Cell: Proliferation, Differentiation and Death. 15-17 Settembre 1996 Baia Paraelios, Italia. C-17.

7) NITRIC OXIDE IS INVOLVED IN THERMOREGULATORY ACTIVITY IN THE RAT. F. Nava, G. Calapai, G. Facciolà, S. Cuzzocrea, A. De Sarro and A.P. Caputi. Atti del Congresso. II International Paraelios Symposium Nitric Oxide and Cell: Proliferation, Differentiation and Death. 15-17 Settembre, 1996 Baia Paraelios Italia.C-16

8) MODIFICAZIONI CARDIOVASCOLARI DA PLASMA ATTIVATO CON ZYMOSAN POTREBBERO ESSERE MEDIATI DALLA PRODUZIONE DI PEROSSINITRITOS. Cuzzocrea, B. Zingarelli, A.P. Caputi, A.L. Salzman, C. SzabòIII Incontro Nazionale di Farmacologia del cuore, dei vasi e del microcircolo. 20-21 Settembre, 1996 Maratea Italia. Le Basi Razionali della Terapia pag. 56.

9) ATTUALITA’ IN TEMA DI SINDROME ORALE ALLERGICA. F. Purello D’ Ambrosio, S. Gangemi, M. Cilia, A. Musarra, G.F. Bagnato, S. Cuzzocrea. Atti del Congresso. VII Congresso Nazionale Dell’ Associazione italiana di Aerobiologia, Italia 45-48.

10) MULTIPLE ORGAN FAILURE FOLLOWING ZYMOSAN-INDUCED PERITONITIS IS MEDIATED BY NITRIC OXIDE. S. Cuzzocrea, B. Zingarelli, L. Sautebin, M. Di Rosa, A. P. Caputi. The 26th Educational & Scientific Symposium of The Society of Critical Care Medicine, Febbraio 6-10 1997, San Diego, California, USA. Crit. Care Med. 25: A71, abs. 102, 1997

11) ACTIVATION OF POLY (ADP-RIBOSE) SYNTHETASE (PARS) IV INVOLVED IN THE ENDOTHELIAL DYSFUNCTION IN RESPONSE TO PEROXTNITRITE AND ENDOTOXIN SHOCK. C. Szabò, B. Zingarelli, S. Cuzzocrea, A. L. Salzman. The 26th Educational & Scientific Symposium of The Society of Critical Care Medicine, Febbraio 6-10 1997, San Diego, California, USA. Crit. Care Med. 25: A34, abs. 6, 1997.

12) CARDIOVASCULAR DERANGEMENT BY ZYMOSAN-ACTIVATED PLASMA MAY BE MEDIATED VIA THE PRODUCTION OF PEROXYNITRITE.S. Cuzzocrea, B. Zingarelli, A.P. Caputi, A. L. Salzman and C. Szabò. The 26th Educational & Scientific Symposium of The Society of Critical Care Medicine, Febbraio 6-10 1997, San Diego, California, USA. Crit. Care Med. 25: A52, abs. 35, 1997.

13) CITOCHIINE E DRINKING BEHAVIOUR. G. Facciolà, G. Calapai, S. Cuzzocrea, F. Nava, A.P. Caputi. V Congresso Nazionale Giovani Cultori di Neuroscienze Pisa Italia. abs. B8, 1997.

14) LA DISIDRATAZIONE RIDUCE LA FEBBRE INDOTTA DA ENDOTOSSINA NEL RATTO. F. Nava, G. Calapai, G. Facciolà, S. Cuzzocrea, A. De Sarro, A.P. Caputi. V Congresso Nazionale Giovani Cultori di Neuroscienze Pisa Italia. abs. D14, 1997.

15) ROLE OF NITRIC OXIDE ON MULTIPLE ORGAN FAILURE INDUCED BY ZYMOSAN.

S. Cuzzocrea, B. Zingarelli, L. Sautebin, M. Di Rosa, A. P. Caputi. 4th International Congress on The Immune Consequences of Trauma, Shock and Sepsi Mechanism and Therapeutic Approaches 4-8 Marzo 1997 Monaco, Germania. Shock 7 (S1): abs.278, 1997.

16) ROLE OF POLY-ADP RIBOYLTRANSFERASE IN SPLANCHNIC ARTERY OCCLUSION SHOCK IN THE RAT. S. Cuzzocrea, B. Zingarelli, A.L. Salzman, and C. Szabó. 4th International Congress on The Immune Consequences of Trauma, Shock and Sepsi Mechanism and Therapeutic Approaches 4-8 Marzo 1997 Monaco, Germania. Shock 7 (S1): abs.131, 1997.

17) POLY (ADP-RIBOSE) SYNTHETASE ACTIVATION INDUCED BY PEROXYNITRITE MEDIATES MYOCARDIAL ISCHEMIA AND REPERFUSION INJURY. B. Zingarelli, S. Cuzzocrea, M. O’Connor, Z. Zsengeller, A.L. Salzman, and C. Szabó. 4th International Congress on The Immune Consequences of Trauma, Shock and Sepsi Mechanism and Therapeutic Approaches 4-8 Marzo 1997 Monaco, Germania. Shock 7 (S1): abs.351, 1997.

18) ENDOGENOUS GLUTATHIONE PROTECTS AGAINST THE VASCULAR FAILURE IN RESPONSE TO PEROXYNITRITE AND ENDOTOXIC SHOCK. S. Cuzzocrea, B. Zingarelli, A.L. Salzman, and C. Szabó. Experimental Biology ‘97 Aprile 6-9, 1997, New Orleans, LA, USA. The FASEB J. 11: 397, 1997.

19) PYRAZOLONE-1- CARBOXAMIDE AND RELATED COMPOUNDS AND NOVEL INHIBITORS OF NITRIC OXIDE SYNTHASE: PHARMACOLOGICAL CHARACTERIZATION IN CULTURED CELLS AND VASCULAR RING. G.J. Southan, D. Gauld, A. Lubeskie, B. Zingarelli, S. Cuzzocrea, A.L. Salzman, D.J. Wolff and C. Szabó. Experimental Biology ‘97 Aprile 6-9, 1997, New Orleans, LA, USA. The FASEB J. 11: 2755, 1997.

20) CONTRIBUTION OF POLY-ADP RIBOYLTRANSFERASE ACTIVATION TO THE PATHOGENESIS OF SPLANCHNIC ARTERY OCCLUSION SHOCK IN THE RAT S. Cuzzocrea, B. Zingarelli, G. Costantino, A.L. Salzman, A.P. Caputi and C. Szabó.XVIII Società Italiana di Farmacologia 30 Aprile - 3 Maggio 1997 Bari, Italia,. Pharmacological Research 35 (supl.): 83 1997.

21) ROLE OF PEROXYNITRITE AND POLY-ADP RIBOYLTRANSFERASE ACTIVATION IN MYOCARDIAL ISCHEMIA AND REPERFUSION INJURY B. Zingarelli, S. Cuzzocrea, M. O’Connor, Z. Zsengeller, A.L. Salzman and C. Szabó.XVIII Società Italiana di Farmacologia 30 Aprile - 3 Maggio 1997 Bari, Italia,. Pharmacological Research 35 (supl.): 83 1997.

22) PEROXYNITRITE FORMATION AND (ADP-RIBOSE) SYNTHETASE ACTIVATION CONTRIBUTE TO INCREASE EPITELIAL PERMEABILITY IN SPLANCHNIC ARTERY OCCLUSION AND REPERFUSION. A. Szabò, S. Cuzzocrea, B. Zingarelli, A.L. Salzman and C. Szabó. The 20th Annual Conference on Shock, Indian Wells, California, USA Giugno 15-18, 1997. Shock 7: abs.66, 1997.

23) MECHANISM OF THE VASCULAR FAILURE INDUCED BY ZYMOSAN-ACTIVATED PLASMA: ROLE OF PEROXYNITRITE AND ACTIVATION OF POLY (ADP-RIBOSE) SYNTHETASE. S. Cuzzocrea, B. Zingarelli, M. O’Connor, A.L. Salzman and C. Szabó. The 20th Annual Conference on Shock, Indian Wells, California, USA Giugno 15-18, 1997. Shock 7: abs.215, 1997.

24) PEROXYNITRITE AND ENDOTOXIN SHOCK CAUSE VASCULAR HYPO-REACTIVITY AND ENDOTHELIAL DYSFUNCTION: ROLE OF POLY (ADP-RIBOSE) SYNTHETASE ACTIVATION AND PROTECTION BY ENDOGENOUS GLUTATHIONE. C. Szabó, B. Zingarelli, S. Cuzzocrea, and A.L. Salzman. The 20th Annual Conference on Shock, Indian Wells, California, USA Giugno 15-18, 1997. Shock 7: abs.67, 1997.

25) NITRIC OXIDE AND PROSTAGLANDIN IN A EXPERIMENTAL MODEL OF MULTIPLE ORGAN FAILURE. S. Cuzzocrea, B. Zingarelli, L. Sautebin, M. Di Rosa, A. P. Caputi. The 20th Annual Conference on Shock, Indian Wells, California, USA Giugno 15-18, 1997. Shock 7: abs.107, 1997.

26) ROLE OF POLY (ADP-RIBOSE) SYNTHETASE (PARS) IN THE PEROXYNITRITE AND NITRIC OXIDE-INDUCED CYTOTOXICITY: STUDIES IN A PARS KNOCKOUT FIBROBLAS CELL LINE. C. Szabó, L. Viràg, B. Zingarelli, G.S. Scott, S. Cuzzocrea, M. O’Connor, A.L. Salzman.The 5th International Meeting on Nitric Oxide, Kyoto Japan, Settembre 15-19, 1997. Japan J. Pharmacol. 75 (S1): 101P (abs. P-316), 1997.

26) NITRIC OXIDE AND PEROXYNITRITE RELATED ANTIINFLAMMATORY EFFECTS OF MELATONINC. Szabó, E. Gilard, S. Cuzzocrea, P. Hake, B. Zingarelli, A.L. Salzman.The 5th International Meeting on Nitric Oxide, Kyoto Japan Settembre 15-19, 1997. Japan J. Pharmacol. 75 (S1): 98P (abs. P-303), 1997.

27) ANTIINFLAMMATORY EFFECTS OF MERCAPTOETHYLGUANIDINE, AN INHIBITOR OF THE INDUCIBLE NITRIC OXIDE SYNTHASE AND A SCAVENGER OF PEROXYNITRITE.C. Szabó, S. Cuzzocrea, P. Hake, B. Zingarelli, A.L. Salzman.The 5th International Meeting on Nitric Oxide, Kyoto Japan Settembre 15-19, 1997. Japan J. Pharmacol. 75 (S1): 103P (abs. P-323), 1997.

28) ROLE OF PEROXYNITRITE AND POLY (ADP-RIBOSE) SYNTHETASE (PARS) ACTIVATION EXPERIMENTAL COLITISA.L. Salzman, B. Zingarelli, S. Cuzzocrea, C. Szabó.The 5th International Meeting on Nitric Oxide, Kyoto Japan Settembre 15-19, 1997. Japan J. Pharmacol. 75 (S1): 15P (abs. 52), 1997.

29) POLY (ADP-RIBOSE) SYNTHETASE MODULATES EXPRESSION OF P-SELECTINE AND ICAM-1 IN MYOCARDIAL ISCHEMIA-REPERFUSION INJURYC. Szabó, B. Zingarelli, S. Cuzzocrea, A.L. Salzman.The 5th International Meeting on Nitric Oxide, Kyoto Japan Settembre 15-19, 1997. Japan J. Pharmacol. 75 (S1): 101P (abs. P-314), 1997.

30) PROTECTIVE EFFECT OF AN INHIBITOR OF POLY (ADP-RIBOSE) SYNTHETASE IN COLLAGEN-INDUCED ARTHRITIS.C. Szabó, S. Cuzzocrea, P. Hake, G.S. Scott, R. Hirsch, A.L. Salzman.The 5th International Meeting on Nitric Oxide, Kyoto Japan Settembre 15-19, 1997. Japan J. Pharmacol. 75 (S1): 102P (abs. P-317), 1997.

31) EVIDENCE FOR THE PEROXYNITRITE - POLY (ADP-RIBOSE) SYNTHETASE PATHWAY IN THE PATHOGENESIS OF MESENTERIC ARTERY REPERFUSION INJURYC. Szabó, A. Szabò, S. Cuzzocrea, B. Zingarelli, A.L. Salzman.The 5th International Meeting on Nitric Oxide, Kyoto Japan Settembre 15-19, 1997. Japan J. Pharmacol. 75 (S1): 101P (abs. P-315), 1997.

33) EFFECT OF HYPERBARIC OXYGEN THERAPY ON ZYMOSAN-INDUCED SHOCK MODEL.C. Luongo, F. Imperatore, S. Cuzzocrea, MA. Scafuro, V. de Novellis, F. Portolano, M. Starace, F. Rossi51° Congresso nazionale della società Italiana di Anestesia, Analgesia, Rianimazione e Terapia intensiva, Torino, Italia, 1-4 Ottobre 1997, Minerva Anestesiologica 3 (S2): 3, 1997.

34) PEROXYNITRITE-MEDIATED DNA STRAND BREAKAGE ACTIVATES POLY (ADP-

RIBOSE) SYNTHETASE AND CAUSES CELLULAR ENERGY DEPLETION IN CARRAGEENAN-INDUCED PLEURISYS. Cuzzocrea, B. Zingarelli, A.P. CaputiXII Congresso Nazionale Associazione Italiana di Immunofarmacologia. Ottobre 23-24, 1997 atti del congresso pag. 40.

35) EFFECT OF 3-AMINOBENZAMIDE, AN INHIBITOR OF POLY (ADP-RIBOSE) SYNTHETASE ON THE EXPRESSION OF P-SELECTIN AND INTERCELLULAR ADHESION MOLECULE-1 IN MYOCARDIAL ISCHEMIA-REPERFUSION.B. Zingarelli, S. Cuzzocrea, A.L. Salzman, C. SzabòThe 27th Educational and Scientific Symposium of the Society of Critical Care Medicine, Febbraio 4-8, 1998, San Antonio, Texas, U.S.A. Crit. Care Med. 26 (Suppl.): A35, abs. 5, 1998.

36) MELATONIN INHIBITS THE EXPRESSION OF THE INDUCIBLE ISOFORM OF NITRIC OXIDE SYNTASE AND EXERTS PROTECTIVE EFFECTS IN A CARRAGEENAN-MODEL OF INFLAMMATION.E. Gilard, S. Cuzzocrea, B. Zingarelli, H.R. Wong, A.L. Salzman, C. SzabòThe 27th Educational and Scientific Symposium of the Society of Critical Care Medicine, Febbraio 4-8, 1998, San Antonio, Texas, U.S.A. Crit. Care Med. 26 (Suppl.): A74, abs. 124, 1998.

37) PHARMACOLOGICAL INHIBITION, OR GENETIC ABLATION OF POLY (ADP-RIBOSE) SYNTHETASE EXERTS ANTI-INFLAMMATORY EFFECTS IN A ZYMOSAN INDUCED MODEL OF MULTIPLE ORGAN FAILURE.Szabò, S. Cuzzocrea, B. Zingarelli, A.L. Salzman The 27th Educational and Scientific Symposium of the Society of Critical Care Medicine, Febbraio 4-8, 1998, San Antonio, Texas, U.S.A. Crit. Care Med. 26 (Suppl.): A76, Abs. 134, 1998.

38) POLY (ADP-RIBOSYL) SYNTHETASE MEDIATES INTESTINAL MUCOSAL BARRIER DYSFUNCTION AFTER MESENTERIC ISCHEMIA Szabò, A.L. Salzman, B. Zingarelli, S. Cuzzocrea, C. Szabò.Experimental Biology ‘98 Aprile 18-22, 1998, San Francisco, CA, USA. The FASEB J. 12: 5845, 1998.

39) INTERLEIKIN-6 KNOCK OUT MICE EXHIBIT A RESISTANCE TO MULTIPLE ORGAN FAILURE INDUCED BY ZYMOSAN S. Cuzzocrea, G .B. De Sarro, G. Costantino, A. De Sarro, A. P. CaputiThe 6th Joint meeting of the Italian, Hungarian and Polish Parmacological Society, Maggio 14-16, 1998, Pisa, Italia. Atti del Congresso: Abs. O33, pag. 13, 1998.

40) ROLE OF PEROXYNITRITE AND POLY (ADP-RIBOSYL) SYNTHETASE ACTIVATION IN CARDIOVASCULAR DEREANGEMENT INDUCED BY ZYMOSAN IN THE RAT S. Cuzzocrea, G. Costantino, B. Zingarelli, A.P. Caputi,

The 6th Joint meeting of the Italian, Hungarian and Polish Parmacological Society, Maggio 14-16, 1998, Pisa, Italia. Atti del Congresso: Abs. P73, pag. 41, 1998.

41) INTERLEIKIN-6 KNOCK OUT MICE EXHIBIT A RESISTANCE TO MULTIPLE ORGAN FAILURE INDUCED BY ZYMOSAN Cuzzocrea, G .B. De Sarro, G. Costantino, A. De Sarro, A. P. CaputiThe 21st Annual Conference on Shock, San Antonio, Texas, U.S.A. Giugno 14-17, 1998. Shock 9: abs. 48, 1998.

42) PEROXYNITRITE-MEDIATED DNA STRAND BREAKAGE ACTIVATES POLY (ADP-RIBOSE) SYNTHETASE AND CAUSES CELLULAR ENERGY DEPLETION IN A NONSEPTIC SHOCK MODEL INDUCED BY ZYMOSAN IN THE RAT.

G. Costantino, S. Cuzzocrea, B. Zingarelli, A.P. CaputiThe 21st Annual Conference on Shock, San Antonio, Texas, U.S.A. Giugno 14-17, 1998. Shock 9: abs.35, 1998.

43) PROTECTIVE EFFECT OF MELATONIN IN A NON-SEPTIC SHOCK MODEL INDUCED BY ZYMOSAN IN THE RATCuzzocrea, G. Costantino, B. Zingarelli, F. Giuffrè, A.P. CaputiThe 21st Annual Conference on Shock, San Antonio, Texas, U.S.A. Giugno 14-17, 1998. Shock 9: abs. 192, 1998.

44)PEROXYNITRITE-DEPENDENT AND PEROXYNITRITE-INDEPENDENT CITOTOXIC MECHANISMS IN THE ABSENCE OF INDUCIBLE NITRIC OXIDE SYNTHETASE. C. Szabó, L. Viràg, B. Zingarelli, A. Szabò, S. Cuzzocrea, A. L. Salzman. The 21st Annual Conference on Shock, San Antonio, Texas, U.S.A. Giugno 14-17, 1998. Shock 202: abs. 192, 1998.

45)THE PROTECTIVE ROLE OF ENDOGENOUS GLUTATHIONE AGAINST PEROXYNITRITE-INDUCED INJURY IN CARRAGEENAN LOCAL INFLAMMATION. S. Cuzzocrea, G. Costantino, B. Zingarelli, GM. Campo, AP. Caputi The 3rd International Conference on “Biochemistry and Molecular Biology of Nitric Oxide”, Los Angeles, USA Luglio 11-15, 1998. Nitric Oxide Biology and Chamistry 2: 106 (abs. F7), 1998.

46) INTERLEUKIN-6 KNOCK OUT MICE EXHIBIT A RESISTANCE TO SPLANCHNIC ARTERY OCCLUSION SHOCK.S. Cuzzocrea, G.B. De Sarro, G. Costantino, A. De Sarro, A.P. CaputiThe 3rd International Conference on “Biochemistry and Molecular Biology of Nitric Oxide”, Los Angeles, USA Luglio 11-15, 1998. Nitric Oxide Biology and Chamistry 2: 123 (abs. I1), 1998

47) PROTECTIVE EFFECT OF MELATONIN ON CELLULAR ENERGY DEPLETION MEDIATED BY PEROXYNITRITE AND POLY (ADP-RIBOSE) SYNTHETASE ACTIVATION IN A NON-SEPTIC SHOCK MODEL INDUCED BY ZYMOSAN IN THE RATS. Cuzzocrea, G. Costantino, F. Giuffrè, AP. CaputiThe 3rd International Conference on “Biochemistry and Molecular Biology of Nitric Oxide”, Los Angeles, USA Luglio 11-15, 1998. Nitric Oxide Biology and Chamistry 2: 106 (abs. F6), 1998

48) PROTECTIVE EFFECT OF N-ACETYLCYSTEINE IN A MULTIPLE ORGAN FAILURE MODEL INDUCED BY ZYMOSAN IN THE RATS. Cuzzocrea, G. Costantino, A.P. CaputiThe 3rd International Conference on “Biochemistry and Molecular Biology of Nitric Oxide”, Los Angeles, USA Luglio 11-15, 1998. Nitric Oxide Biology and Chamistry 2: 106 (abs. F8), 1998

49) INTERLEUKIN-6 KNOCK OUT MICE EXHIBIT RESISTANCE TO SPLANCHNIC ARTERY OCCLUSION SHOCK.

S. Cuzzocrea, G.B. De Sarro, G. Costantino, A. De Sarro, A.P. CaputiThe British Pharmacological Society. Southampton, UK, Settembre 8-11, 1998. Br. J. Pharmacol 125: abs 112P, 1998.

50)THE PROTECTIVE ROLE OF ENDOGENOUS GLUTATHIONE AGAINST PEROXYNITRITE-INDUCED INJURY IN CARRAGEENAN LOCAL INFLAMMATION. S. Cuzzocrea, G. Costantino, B. Zingarelli, AP. CaputiFourth European Congress of Pharmaceutical Sciences, Milano, Italia, Settembre 11-13, 1998. Eur. J. Pharmaceut. Sciences 6: 82 (abs. 328), 1998.

51) PROTECTIVE EFFECT OF MELATONIN ON CELLULAR ENERGY DEPLETION IN A NON-SEPTIC SHOCK MODEL INDUCED BY ZYMOSAN IN THE RATCostantino, S. Cuzzocrea, AP. CaputiFourth European Congress of Pharmaceutical Sciences, Milano, Italia, Settembre 11-13, 1998.Eur. J. Pharmaceut. Sciences 6: 82 (abs. 327), 1998.

52)PROTECTIVE EFFECT OF N-ACETYLCYSTEINE IN A NON-SEPTIC SHOCK MODEL INDUCED BY ZYMOSAN IN THE RATS. Cuzzocrea, G. Costantino, A.P. CaputiFourth European Congress of Pharmaceutical Sciences, Milano, Italia, Settembre 11-13, 1998.Eur. J. Pharmaceut. Sciences 6: 52 (abs. 207), 1998.

53) ROLE OF PEROXYNITRITE AND POLY (ADP-RIBOSE) SYNTHETASE ON CELLULAR ENERGY DEPLETION IN A NONSEPTIC SHOCK MODEL INDUCED BY ZYMOSAN IN THE RAT. S. Cuzzocrea, G. Costantino, B. Zingarelli, A.P. CaputiFourth European Congress of Pharmaceutical Sciences, Milano, Settembre 11-13, 1998.Eur. J. Pharmaceut. Sciences 6: 94 (abs. 373), 1998.

54) INTERLEUKIN-6 KNOCK OUT MICE EXHIBIT A RESISTANCE TO SPLANCHNIC ARTERY OCCLUSION SHOCK.

S. Cuzzocrea, G.B. De Sarro, G. Costantino, A. De Sarro, A.P. CaputiSeminario Dottorandi di Ricerca. Siena, Italia, Settembre 24-26, 1998. Abstract book pag. 73.

55)PROTECTIVE EFFECT OF MELATONIN IN A NON-SEPTIC SHOCK MODEL INDUCED BY ZYMOSAN IN THE RATG. Costantino, S. Cuzzocrea, A.P. CaputiSeminario Dottorandi di Ricerca. Siena, Italia, Settembre 24-26, 1998. Abstract book pag. 72.

56) INTERLEIKIN-6 KNOCK OUT MICE EXHIBIT A RESISTANCE TO MULTIPLE ORGAN FAILURE INDUCED BY ZYMOSAN Cuzzocrea, G .B. De Sarro, G. Costantino, A. De Sarro, A. P. CaputiVibo Valentia Seminars on Shock. Vibo Valentia, Italy. Ottobre 10-12, 1998.

57) CONTRIBUTION OF INTERLEUKIN-6 TO THE ISCHEMIA AND REPERFUSION INJURY.Cuzzocrea, G .B. De Sarro, G. Costantino, A. De Sarro, A. P. CaputiThe 8st Congress of the European Shock Society, La Hulpe, Belgio. Ottobre 15-17, 1998. Shock 10: abs. 13, 1998.

58) PROTECTIVE EFFECT OF N-ACETYLCYSTEINE IN A NON-SEPTIC SHOCK MODEL INDUCED BY ZYMOSAN IN THE RATS. Cuzzocrea, G. Costantino, A.P. CaputiThe 8st Congress of the European Shock Society, La Hulpe, Belgio. Ottobre 15-17, 1998. Shock 10: abs. 48, 1998.

59) ROLE OF INTERLEUKIN-6 IN A NON-SEPTIC SHOCK MODEL INDUCED BY ZYMOSAN Cuzzocrea, G .B. De Sarro, G. Costantino, A. De Sarro, A. P. CaputiSecond Joint Meeting of the International Cytokine Society and International Society for Interferon and Cytokine Research Gerusalemme, Israele, Ottobre 25-30, 1998. Eur. Cytokine Network 9: abs. 410, pag. 330, 1998.

60) ROLE OF INTERLEUKIN-6 A IN SPLANCHNIC ARTERY OCCLUSION SHOCK Cuzzocrea, G .B. De Sarro, G. Costantino, A. De Sarro, A. P. CaputiSecond Joint Meeting of the International Cytokine Society and International Society for Interferon and Cytokine Research Gerusalemme, Israele, Ottobre 25-30, 1998. Eur. Cytokine Network 9: abs. 411, pag. 330, 1998.

61) CONTRIBUTION OF INTERLEUKIN-6 TO THE PATHOGENESIS OF SPLANCHNIC ARTERY OCCLUSION SHOCK.S. Cuzzocrea, G.B. De Sarro, G. Costantino, G. Ciliberto, A. De Sarro, A. P. CaputiBiomedicina ’98 Meeting on Molecular Medicine Firenze, Italia. Novembre 25-27, 1998.

62) PROTECTIVE EFFECT OF N-ACETYLCYSTEINE ON CELLULAR ENERGY DEPLETION IN A NON-SEPTIC SHOCK MODEL INDUCED BY ZYMOSAN IN THE RATS. Cuzzocrea, G. Costantino, A.P. CaputiBiomedicina ’98 Meeting on Molecular Medicine Firenze, Italia. Novembre 25-27, 1998.

63) PROTECTIVE EFFECT OF POLY (ADP-RIBOSE) SYNTHETASE INHIBITION ON MULTIPLE ORGAN FAILURE FOLLOWING ZYMOSAN-INDUCED PERITONITISS. Cuzzocrea, B. Zingarelli, G. Costantino, A.P. CaputiBiomedicina ’98 Meeting on Molecular Medicine Firenze, Italia. Novembre 25-27, 1998.

64) CARDIOVASCULAR DERANGEMENT BY ZYMOSAN-ACTIVATED PLASMA MAY BE MEDIATED VIA THE PRODUCTION OF PEROXYNITRITES. Cuzzocrea, A.P. CaputiInternational Conference on “In vitro cytotoxicity mechanisms” Rama Italia Gennaio 25-27, 1999. Abstract book pag. 38.

65) BENEFICIAL EFFECT OF N-ACETYLCYSTEINE ON CELLULAR ENERGY DEPLETION IN A NON-SEPTIC SHOCK MODEL INDUCED BY ZYMOSAN IN THE RATS. Cuzzocrea, G. Costantino, A.P. CaputiInternational Conference on “In vitro cytotoxicity mechanisms” Rama Italia Gennaio 25-27, 1999. Abstract book pag. 39.

66) PEROXYNITRITE AND POLY (ADP-RIBOSE) SYNTHETASE - CAUSES CELLULAR ENERGY DEPLETION IN A NONSEPTIC SHOCK MODEL INDUCED BY ZYMOSAN IN THE RAT. S. Cuzzocrea, G. Costantino, A.P. CaputiInternational Conference on “In vitro cytotoxicity mechanisms” Rama Italia Gennaio 25-27, 1999. Abstract book pag. 31.

67) ROLE OF ENDOGENOUS GLUTATHIONE IN CARRAGEENAN-INDUCED LOCAL INFLAMMATION. S. Cuzzocrea, G. Costantino, B. Zingarelli, AP. Caputi Fundamental & Clinical Pharmacology in press 1999. Società Italiana di Farmacologia and French association des Pharmacologites, Nantes 15-17 Marzo 1999 Francia.

68) CONTRIBUTION OF INTERLEUKIN-6 TO THE NON-SEPTIC SHOCK MODEL INDUCED BY ZYMOSAN.S. Cuzzocrea, G.B. De Sarro, G. Costantino, A. De Sarro, A.P. CaputiFundamental & Clinical Pharmacology in press 1999. Società Italiana di Farmacologia and French association des Pharmacologites, Nantes 15-17 Marzo 1999 Francia.

69) PROTECTIVE EFFECT OF N-ACETYLCYSTEINE IN A MULTIPLE ORGAN FAILURE MODEL INDUCED BY ZYMOSAN IN THE RATS. Cuzzocrea, G. Costantino, A.P. CaputiFundamental & Clinical Pharmacology in press 1999. Società Italiana di Farmacologia and French association des Pharmacologites, Nantes 15-17 Marzo 1999 Francia.

70) PROTECTIVE EFFECTS OF MELATONIN IN A RAT MODEL OF SPLANCHNIC ARTERY OCCLUSION AND REPERFUSION G. Costantino, S. Cuzzocrea, E. Mazzon, A. De Sarro, A.P. CaputiThe 4rt International Shock Congress, Philadelphia, Pennsylvania, U.S.A. Giugno 12-16, 1999. Shock 11 abs. 290, 1999.71) BENEFICIAL EFFECTS OF MN(III)TETRAKIS (4-BENZOIC ACID) PORPHYRIN (MNTBAP), A SUPEROXIDE DISMUTASE MIMETIC, IN ZYMOSAN-INDUCED NON-SEPTIC SHOCK S. Cuzzocrea, G. Costantino, E. Mazzon, A. De Sarro, A.P. CaputiThe 4rt International Shock Congress, Philadelphia, Pennsylvania, U.S.A. Giugno 12-16, 1999. Shock 11: abs. 191, 1999.

72) PROTECTIVE EFFECTS OF N-ACETYLCYSTEINE IN A RAT MODEL OF SPLANCHNIC ARTERY OCCLUSION AND REPERFUSION A.P. Caputi, G. Costantino, E. Mazzon, S. CuzzocreaThe 4rt International Shock Congress, Philadelphia, Pennsylvania, U.S.A. Giugno 12-16, 1999. Shock 11: abs. 289, 1999.

73) ROLE OF INTERLEUKIN-6 IN LOCAL INFLAMMATIONS. Cuzzocrea, L. Sautebin, G.B. De Sarro, G. Costantino, L. Rombolà, A. De Sarro, M. Di Rosa, A.P. Caputi. XXIX Concresso Nazionale Società Italiana di Farmacologia 20-23 Giugno 1999 Firenze, Italia,. Pharmacological Research 39 (supl.): 55 1999.

74) INHIBITION BY ENDOGENOUS MELATONIN OF CARRAGEENAN-INDUCED PLEURISY IN THE RAT. S. Cuzzocrea, D. Tan, G. Costantino, R.J. Reiter, A.P. Caputi XXIX Concresso Nazionale Società Italiana di Farmacologia 20-23 Giugno 1999 Firenze, Italia,. Pharmacological Research 39 (suppl.): 81 1999.

75) IN PAW INFLAMMATION INDUCED BY ZYMOSAN-ACTIVATED PLASMA MELATONIN EXERT A PROTECTIVE EFFECTS G. Costantino, S. Cuzzocrea, A.P. Caputi XXIX Concresso Nazionale Società Italiana di Farmacologia 20-23 Giugno 1999 Firenze, Italia,. Pharmacological Research 39 (suppl.): 81 1999.

76) BENEFICIAL EFFECTS OF Mn(III)TETRAKIS (4-BENZOIC ACID) PORPHYRIN, A SUPEROXIDE DISMUTASE MIMETIC, IN CARRAGEENAN-INDUCED PLEURISYS. Cuzzocrea, B. Zingarelli, G. Costantino, A.P. CaputiXXIX Concresso Nazionale Società Italiana di Farmacologia 20-23 Giugno 1999 Firenze, Italia,. Pharmacological Research 39 (suppl.): 82 1999.

77) BENEFICIAL EFFECTS OF N-ACETYLCYSTEINE IN A RAT MODEL OF SPLANCHNIC ARTERY OCCLUSION AND REPERFUSION S. Cuzzocrea, G. Costantino, E. Mazzon, A.P. CaputiXXIX Concresso Nazionale Società Italiana di Farmacologia 20-23 Giugno 1999 Firenze, Italia,. Pharmacological Research 39 (suppl.): 85 1999.

78) BENEFICIAL EFFECT OF POLY (ADP-RIBOSE) SYNTHETASE INHIBITION ON MULTIPLE ORGAN FAILURE INDUCED BY ZYMOSAN IN THE RATS. Cuzzocrea, B. Zingarelli, G. Costantino, A.P. CaputiXXIX Concresso Nazionale Società Italiana di Farmacologia 20-23 Giugno 1999 Firenze, Italia,. Pharmacological Research 39 (suppl.): 3 1999.

79) ROLE OF INTERLEUKIN-6 IN ACUTE MODEL OF INFLAMMATIONS. Cuzzocrea, L. Sautebin, G.B. De Sarro, G. Costantino, L. Rombolà, A. De Sarro, M. Di Rosa, A.P. Caputi.2nd European Concress of Pharmacology 3-7 Luglio 1999, Budapest, Ungheria. Fundamental & Clinical Pharmacology 13 (suppl.1) PM1 1999.

80) ROLE OF ENDOGENOUS MELATONIN IN CARRAGEENAN-INDUCED PLEURISY IN THE RAT. S. Cuzzocrea, D. Tan, G. Costantino, R.J. Reiter, A.P. Caputi 2nd European Concress of Pharmacology 3-7 Luglio 1999, Budapest, Ungheria.Fundamental & Clinical Pharmacology 13 (suppl.1) PW13 1999.

81) PROTECTIVE EFFECTS OF Mn(III)TETRAKIS (4-BENZOIC ACID) PORPHYRIN, A SUPEROXIDE DISMUTASE MIMETIC, IN CARRAGEENAN-INDUCED PLEURISY S. Cuzzocrea, B. Zingarelli, G. Costantino, A.P. Caputi2nd European Concress of Pharmacology 3-7 Luglio 1999, Budapest, Ungheria.Fundamental & Clinical Pharmacology 13 (suppl.1) PW49 1999.82) BENEFICIAL EFFECTS OF N-ACETYLCYSTEINE IN A RAT MODEL OF ISCHEMIA AND REPERFUSION INJURY S. Cuzzocrea, G. Costantino, E. Mazzon, A.P. Caputi2nd European Concress of Pharmacology 3-7 Luglio 1999, Budapest, Ungheria.Fundamental & Clinical Pharmacology 13 (suppl.1) PT219 1999.

83) BENEFICIAL EFFECTS OF TEMPOL, A MEMBRANE-PERMEABLE RADICAL SCAVENGER, IN A RODENT MODEL OF CARRAGEENAN-INDUCED PLEURISYS. Cuzzocrea, M. C McDonald, G. Costantino, E. Mazzon, S. Santagati, C. Thiemermann, A.P. Caputi 2nd European Concress of Pharmacology 3-7 Luglio 1999, Budapest, Ungheria.Fundamental & Clinical Pharmacology 13 (suppl.1) PW49 1999.

84) EFFECTS OF VARIOUS CONVULSANT ON INTERLEUKIN-6 DEFICIENT MICEG.B. De Sarro, S. Cuzzocrea, G. Costantino, A. De Sarro,.2nd European Concress of Pharmacology 3-7 Luglio 1999, Budapest, Ungheria. Fundamental & Clinical Pharmacology 13 (suppl.1) PS55 1999.

85) BENEFICIAL EFFECTS OF TEMPOL, A MEMBRANE-PERMEABLE RADICAL SCAVENGER, IN AN EXPERIMENTAL MODEL OF COLLAGEN-INDUCED ARTHRITIS S. Cuzzocrea, M.C. McDonald, G. Costantino, E. Mazzon, D. Britti, A.P. Caputi, C. ThiemermannThe 6th International Meeting on “Biology of Nitric Oxide”, Stoccolma, Svezia, Settembre 5-8, 1999. Acta Physiol. Scand. 167: 90 (abs. P-272), 1999.

86) ROLE OF INDUCIBLE NITRIC OXIDE SYNTHETASE IN LOCAL INFLAMMATIONS. Cuzzocrea, L. Sautebin, G. Costantino, G. Calabrò, A. De Sarro, M. Di Rosa, A.P. Caputi.The 6th International Meeting on “Biology of Nitric Oxide”, Stoccolma, Svezia, Settembre 5-8, 1999. Acta Physiol. Scand. 167: 82 (abs. P-243), 1999.

87) PROTECTIVE EFFECTS OF N-ACETYLCYSTEINE ON ISCHEMIC BRAIN INJURYS. Cuzzocrea, G. Costantino, E. Mazzon, A. De Sarro, A.P. Caputi The 6th International Meeting on “Biology of Nitric Oxide”, Stoccolma, Svezia, Settembre 5-8, 1999. Acta Physiol. Scand. 167: 25 (abs. P-19), 1999.

88) EFFECTS OF TEMPOL, A MEMBRANE-PERMEABLE RADICAL SCAVENGER, IN AN RAT MODEL OF COLLAGEN-INDUCED ARTHRITIS S. Cuzzocrea, M.C. McDonald, G. Costantino, E. Mazzon, D. Britti, A.P. Caputi, C. Thiemermann.5th International Symposium on “Multiple Risk Factor in Cardiovascular Disease: Globall Assessment and Intervention”, Venezia, Italia, Ottobre 28-31, 1999. (pag 75), 1999.89) PEROXYNITRITE DECOMPOSITION CATALYST AND SPLANCHNIC ARTERY OCCLUSION AND REPERFUSIONS. Cuzzocrea, TP. Misko, G. Costantino, A.P. Caputi, H. Macarthur and D. Salvemini 5th International Symposium on “Multiple Risk Factor in Cardiovascular Disease: Globall Assessment and Intervention”, Venezia, Italia, Ottobre 28-31, 1999. (pag 76), 1999.

90) BENEFICIAL EFFECTS OF N-ACETYLCYSTEINE ON ISCHEMIC BRAIN INJURYS. Cuzzocrea, G. Costantino, E. Mazzon, A. De Sarro, A.P. Caputi5th International Symposium on “Multiple Risk Factor in Cardiovascular Disease: Globall Assessment and Intervention”, Venezia, Italia, Ottobre 28-31, 1999. (pag 9), 1999.

91) EFFECTS OF TEMPOL, A MEMBRANE-PERMEABLE RADICAL SCAVENGER, IN A RODENT MODEL OF COLLAGEN-INDUCED ARTHRITIS S. Cuzzocrea, M.C. McDonald, G. Costantino, E. Mazzon, D. Britti, A.P. Caputi, C. Thiemermann7th Vienna Shock Forum, Vienna Austria, Novembre 13-16, 1999. Shock 12: (abs 198), 1999.

92) EFFECTS OF MELATONIN IN A RAT MODEL OF SPLANCHNIC ARTERY OCCLUSION AND REPERFUSION S. Cuzzocrea, G. Costantino, E. Mazzon, A. De Sarro, A.P. Caputi7th Vienna Shock Forum, Vienna Austria, Novembre 13-16, 1999. Shock 12: (abs. 89), 1999.

93) BENEFICIAL EFFECTS OF PEROXYNITRITE DECOMPOSITION CATALYST IN A RAT MODEL OF SPLANCHNIC ARTERY OCCLUSION AND REPERFUSIONS. Cuzzocrea, TP. Misko, G. Costantino, A.P. Caputi, H. Macarthur and D. Salvemini 7th Vienna Shock Forum, Vienna Austria, Novembre 13-16, 1999. Shock 12: (abs. 149), 1999.

94) ROLE POLY (ADP-RIBOSE) SYNTHETASE ON MULTIPLE ORGAN FAILURE INDUCED BY ZYMOSAN IN THE RATS. Cuzzocrea, A.P. Caputi.XII Convegno Nazionale sui "Processi di ADP-ribosilazione" tenutosi a Camerino il 30 settembre e 1 ottobre '99, The Journal of Biological Regulators & Homeostatic Agents 13, 4 (oct- dec), 1999.

95) ROLE OF INDUCIBLE NITRIC OXIDE SYNTHETASE IN CELLULAR ENERGY DEPLETION IN A NONSEPTIC SHOCK MODEL INDUCED BY ZYMOSAN S. Cuzzocrea, G. Costantino, G. Calabrò, A. De Sarro, 1A.P. Caputi.XII Congresso Nazionale sella Società Italiana di Tossicologia, Bologna, Italia, 23-26 Bologna Febbraio 2000, Abstract Book pag 45.

96) ROLE OF ENDOGENOUS MELATONIN IN ACUTE INFLAMMATIONS. Cuzzocrea, D. Tan, G. Costantino, R.J. Reiter, A.P. Caputi XII Congresso Nazionale sella Società Italiana di Tossicologia, Bologna, Italia, 23-26 Bologna Febbraio 2000, Abstract Book pag 46.

97) BENEFICIAL EFFECT OF TEMPOL, A MEMBRANE-PERMEABLE RADICAL SCAVENGER, ON THE MULTIPLE ORGAN FAILURE INDUCED BY ZYMOSAN IN THE RAT.S. Cuzzocrea, M.C. McDonald, H. Mota-Filipe, A.P. Caputi, C. ThiemermannXII Congresso Nazionale sella Società Italiana di Tossicologia, Bologna, Italia, 23-26 Bologna Febbraio 2000, Abstract Book pag 47.

98) EFFECTS OF MELATONIN ON ISCHEMIC BRAIN INJURY S. Cuzzocrea, G. Costantino, E. Gitto, E. Mazzon, F. Fulia, I. Serraino, S. Cordaro, I. Berberi A. De Sarro, A.P. Caputi 5th International Congress on The Immune Consequences of Trauma, Shock and Sepsi Mechanism and Therapeutic Approaches 29-4 Marzo 2000 Monaco, Germania. Shock 13, abs 237, 2000.

99) EFFECTS OF N-ACETYLCYSTEINE IN ISCHEMIA AND REPERFUSION INJURY S. Cuzzocrea, E. Mazzon, G. Costantino, I. Serraino, A. De Sarro, A.P. Caputi5th International Congress on The Immune Consequences of Trauma, Shock and Sepsi Mechanism and Therapeutic Approaches 29-4 Marzo 2000 Monaco, Germania. Shock 13, abs 250, 2000.

100) EFFECTS OF TEMPOL, A MEMBRANE-PERMEABLE RADICAL SCAVENGER, ON THE MULTIPLE ORGAN FAILURE INDUCED BY ZYMOSAN IN THE RATS. Cuzzocrea, M.C. McDonald, E. Mazzon, H. Mota Filipe, V. Lepore, M.L. Terranova, A.

Ciccolo, A.P. Caputi, C. Thiemermann.5th International Congress on The Immune Consequences of Trauma, Shock and Sepsi Mechanism and Therapeutic Approaches 29-4 Marzo 2000 Monaco, Germania. Shock 13, abs 248, 2000.

101) INHIBITION OF THE ACTIVATION OF NFkB WITH CALPAIN INHIBITOR 1 REDUCES THE MULTIPLE ORGAN FAILURE IN ENDOTOXIC AND HEMORRHAGIC SHOCK M.C. McDonald, H. Ruetten, H. Mota Filipe, S. Cuzzocrea, C. Thiemermann.5th International Congress on The Immune Consequences of Trauma, Shock and Sepsi Mechanism and Therapeutic Approaches 29-4 Marzo 2000 Monaco, Germania. Shock 13, abs 668, 2000.

102) CALPAIN INHIBITOR I REDUCES THE COLON INJURY CAUSED BY DINITROBENZENE SULFONIC ACID IN THE RAT S. Cuzzocrea, M.C. McDonald, E. Mazzon, V. Lepore, A. Ciccolo, A.P. Caputi, C. ThiemermannThe 23rd Annual Conference on Shock, Snowbird, Utha, U.S.A. Giugno 3-6, 2000. Shock 13, abs. 112, 2000.103) PROTECTIVE EFFECT OF N-ACETYLCYSTEINE, A FREE RADICAL SCAVENGER, ADMINISTRATION ON GENTAMICIN-INDUCED ACUTE RENAL FAILURE IN RATS.S. Cuzzocrea, E. Mazzon, I. Serraino, G. Calabrò, D. Britti, G. Mazzullo, A. De Sarro, A.P. CaputiThe 23rd Annual Conference on Shock, Snowbird, Utha, U.S.A. Giugno 3-6, 2000. Shock 13, abs. 76, 2000.

104) PROTECTIVE EFFECTS OF M40401 A SUPEROXIDE DISMUTASE MIMETIC IN A RAT MODEL OF SPLANCHNIC ARTERY OCCLUSION AND REPERFUSIONS. Cuzzocrea, E. Mazzon, G. Calabrò, G. Costantino, AP. Caputi, D.P. Riley, D. SalveminiThe 23rd Annual Conference on Shock, Snowbird, Utha, U.S.A. Giugno 3-6, 2000. Shock 13, abs. 168, 2000.

105) EFFECTS OF N-ACETYLCYSTEINE ON ISCHEMIC BRAIN INJURY

S. Cuzzocrea, G. Costantino, E. Mazzon, I. Serraino, G. Calabrò, G. Cucinotta, A. De Sarro, A.P. Caputi The 23rd Annual Conference on Shock, Snowbird, Utha, U.S.A. Giugno 3-6, 2000. Shock 13, abs. 204, 2000.

106) PROTECTIVE EFFECT OF TEMPOL, A MEMBRANE-PERMEABLE RADICAL SCAVENGER, ON THE MULTIPLE ORGAN FAILURE INDUCED BY ZYMOSAN IN THE RATS. Cuzzocrea, M.C. McDonald, E. Mazzon, V. Lepore, A. Ciccolo, A.P. Caputi, C. Thiemermann

The 23rd Annual Conference on Shock, Snowbird, Utha, U.S.A. Giugno 3-6, 2000. Shock 13, abs. 169, 2000.

107) BENEFICIAL EFFECTS OF N-ACETYLCYSTEINE IN A RAT MODEL OF SPLANCHNIC ARTERY OCCLUSION AND REPERFUSION L. Dugo, S Cuzzocrea, E. Mazzon, A.P. Caputi.VII Congresso Nazionale della Società Italiana di Ricerche Cardiovascolari, Bologna, 20-22 Settembre 2000.

108) BENEFICIAL EFFECTS OF M40401 A SUPEROXIDE DISMUTASE MIMETIC IN A RAT MODEL OF SPLANCHNIC ISCAEMIA AND REPERFUSION.S. Cuzzocrea, E. Mazzon, G. Calabrò, G. Costaantino, A.P. Caputi, D.P. Riley D. Salvemini. VII Congresso Nazionale della Società Italiana di Ricerche Cardiovascolari, Bologna, 20-22 Settembre 2000.

109) RUOLO DELLA NITROSSIDO SINTASI INDUCIBILE (INOS) NEL DANNO SISTEMICO D’ORGANO INDOTTO DA ZYMOSAN. L. Dugo, E. Mazzon, A.P. Caputi, S. Cuzzocrea. VI Convegno Nazionale, IV Convegno Monotematico SIF Aspetti Biologici dell’Ossido di Azoto, Urbino-Collegio del Colle, 6-7 Ottobre 2000.

110) EFFETTI PROTETTIVI DELLA DECOMPOSIZIONE CATALITICA DEL PEROSSINITRITO IN UN MODELLO DI OCCLUSIONE E RIPERFUSIONE DELL’ARTERIA SPLANCNICA NEL RATTO. S. Cuzzocrea, T.P. Misko, G. Costantino, L. Dugo, A.P. Caputi, H. Macarthur, D. Salvemini. VI Convegno Nazionale, IV Convegno Monotematico SIF Aspetti Biologici dell’Ossido di Azoto, Urbino-Collegio del Colle, 6-7 Ottobre 2000.

110) DEFLAZACORT REDUCES THE DEVELOPMENT OF NASAL POLYPOSIS: RELATIONSHIP TO ITS INHIBITORY EFFECT ON NITRIC OXIDE AND PEROXYNITRITE PRODUCTION AND ITS POLY(ADP.RIBOSE) SYNTHASE REDUCING ACTIVITY.F. Cascio, I. Serraino, L. Dugo, A.P. Caputi, S. Cuzzocrea. Immunopharmacology and Immunoterapy Today, XIV Congresso Nazionale della Società Internazionale di Immunofarmacologia e della Società Italiana di Immunofarmacologia, Firenze, 10-11 Novembre 2000.

111) INDUIBLE NITRIC OXIDE SYNTHASE KNOCK OUT MICE EXHIBIT A RESISTANCE TO CARRAGEENAN-INDUCED LOCAL INFLAMMATION.S. Cuzzocrea, E. Mazzon, L. Dugo, A. De Sarro, A.P. Caputi. Immunopharmacology and Immunoterapy Today, XIV Congresso Nazionale della Società Internazionale di Immunofarmacologia e della Società Italiana di Immunofarmacologia, Firenze, 10-11 Novembre 2000.

112) THE TYROSINE KINASE INHIBITOR TYRPHOSTIN AG126 REDUCES THE DEVELOPMENT OF ACUTE AND CHRONIC INFLAMMATION.

S. Cuzzocrea, M.C. Mc Donald, E. Mazzon, L. Dugo, A.P. Caputi, C. Thiemermann. Immunopharmacology and Immunoterapy Today, XIV Congresso Nazionale della Società Internazionale di Immunofarmacologia e della Società Italiana di Immunofarmacologia, Firenze, 10-11 Novembre 2000.

113) EFFECT OF MELATONIN ON CELLULAR ENERGY DEPLETION MEDIATED BY PEROXYNITRITE AND POLY(ADP-RIBOSE) SYNTHASE ACTIVATION IN AN ACUTE MODEL OF INFLAMMATION. L. Dugo, A. De Sarro, A.P. Caputi, S. Cuzzocrea. Immunopharmacology and Immunoterapy Today, XIV Congresso Nazionale della Società Internazionale di Immunofarmacologia e della Società Italiana di Immunofarmacologia, Firenze, 10-11 Novembre 2000.

114) PROTECTIVE EFFECTS OF CELECOXIB IN LUNG INJURY AND RED BLOOD CELLS MODIFICATION INDUCED BY CARRAGEENAN IN THE RAT. S. Cuzzocrea, E. Mazzon, L. Dugo, I. Serraino, A De Sarro, A.P. Caputi. XXX National Congress of The Italian Pharmacology Society, Genova, Italia, 30 Maggio-2 Giugno 2001. Pharmacological Research, 43: 28, 2001.

115) EFFECTS OF 5-AMINOISOQUINOLINONE, A WATER-SOLUBLE, POTENT INHIBITOR OF THE ACTIVITY OF POLY (ADP-RIBOSE) POLYMERASE, IN A RODENT MODEL OF LUNG INJURY. I. Serraino, M.C. Mc Donald, E. Mazzon, L. Dugo, M. Threadgill, C. Thiemermann, A.P. Caputi. S. Cuzzocrea. XXX National Congress Of The Italian Pharmacology Society, Genova, Italia, 30 Maggio-2 Giugno 2001. Pharmacological Research, 43: 62, 2001.

116) PHARMACOLOGICAL MANIPULATION OF THE INFLAMMATORY CASCADE BY THE SUPEROXIDE DISMUTASE MIMETIC, M40403.S. Cuzzocrea, E. Mazzon, L. Dugo, D. P. Riley, I Serraino, A.P. Caputi, D. Salvemini. XXX National Congress of The Italian Pharmacology Society, Genova, Italia, 30 Maggio-2 Giugno 2001. Pharmacological Research, 43: 91, 2001.

117) BENEFICIAL EFFECTS OF M40401 A SUPEROXIDE DISMUTASE MIMETIC IN A RAT MODEL OF SPLANCHNIC ARTERY OCCLUSION AND REPERFUSION. S. Cuzzocrea, E. Mazzon, I Serraino, L. Dugo, A.P. Caputi, D. P. Riley, D. Salvemini. XXX National Congress of The Italian Pharmacology Society, Genova, Italia, 30 Maggio-2 Giugno 2001. Pharmacological Research, 43: 101, 2001.

118) ROLE OF INDUCIBLE NITRIC OXIDE SYNTHASE IN THE INITIATION OF THE INFLAMMATORY RESPONSE AFTER POSTISCHEMIC INJURY. L. Dugo, S. Cuzzocrea, E. Mazzon, A. De Sarro, C. Thiemermann, A.P. Caputi. XXX National Congress of The Italian Pharmacology Society, Genova, Italia, 30 Maggio-2 Giugno 2001. Pharmacological Research, 43: 102, 2001.

119) INDUCIBLE NITRIC OXIDE SYNTHASE KNOCK OUT MICE ARE PROTECTED FROM BONE LOSS CAUSED BY ESTROGEN DEPLETION. S. Cuzzocrea, E. Mazzon, F. A.J. Van de Loo, A.P. Caputi, A. Maggi. XXX National Congress of The Italian Pharmacology Society, Genova, Italia, 30 Maggio-2 Giugno 2001. Pharmacological Research, 43: 124, 2001.

120) EFFECT OF N-ACETYLCYSTEINE ON GENTAMICIN-MEDIATED NEPHROPATHY IN RAT. De Sarro, E. Mazzon, D. Britti, G. Mazzullo, A.P. Caputi, S. Cuzzocrea. XXX National Congress of the Italian Pharmacology Society, Genova, Italia, 30 Maggio-2 Giugno 2001. Pharmacological Research, 43: 126, 2001.

121) INDUCIBLE NITYRIC OXIDE SYNTHASE STIMULATES DOPAMINERGIC NEURODEGENERATION IN THE PARAQUAT MODEL OF PARKINSON DISEASE. G. De Sarro, N. Costa, R. Marra, G. Donato, S. Cuzzocrea, E. Mazzon, A. De Sarro, D. Rotiroti. XXX National Congress of The Italian Pharmacology Society, Genova, Italia, 30 Maggio-2 Giugno 2001. Pharmacological Research, 43: 140, 2001.

122) BEHAVIOURAL EFFECTS OF PARAQUAT TREATMENT ON FORCED SWIMMING TEST IN TWO MICE STRAINS.M. Arbitrio, G. Trombetta, S. Cuzzocrea, G. De Sarro, D. Rotiroti. XXX National Congress of the Italian Pharmacology Society, Genova, Italia, 30 Maggio-2 Giugno 2001. Pharmacological Research, 43: 144, 2001.

123) EFFECTS OF 5-AMINOISOQUINOLINONE, A WATER SOLUBLE, POTENT INHIBITOR OF THE ACTIVITY OF POLY (ADP-RIBOSE) POLYMERASE, IN A RODENT MODEL OF LUNG INJURY. I. Serraino, M.C. McDonald, E. Mazzon, L. Dugo, M. Threadgill, C. Thiermann, A.P. Caputi, S. Cuzzocrea. Twenty-Fourth Annual Conference on Shock, Marco Island, Florida 9-12 Giugno 2001. Shock 15: Abs. 9, 2001

124) ROLE OF INDUCIBLE NITRIC OXIDE SYNTHASE IN THE INITIATION OF THE INFLAMMATORY RESPONSE AFTER POSTISCHEMIC INJURY. S. Cuzzocrea, L. Dugo, E. Mazzon, A. De Sarro, A.P. Caputi, C. Thiemermann. Twenty-Fourth Annual Conference on Shock, Marco Island, Florida 9-12 Giugno 2001. Shock 15: Abs. 89, 2001

125) BENEFICIAL EFFECTS OF GPI 6150, AN INHIBITOR OF POLY (ADP-RIBOSE) POLYMERASE IN A RAT MODEL OF SPLANCHNIC OCCLUSION AND REPERFUSION. E. Mazzon, L. Dugo, A. De Sarro, J. Li, A.P. Caputi, J. Zhang, S. Cuzzocrea. Twenty-Fourth Annual Conference on Shock, Marco Island, Florida 9-12 Giugno 2001. Shock 15: Abs. 174, 2001

126) INDUCIBLE NITRIC OXIDE SYNTHASE KNOCK OUT MICE EXHIBIT RESISTANCE TO THE ACUTE PANCREATITIS INDUCED BY CERULEIN. T. Centorrino, E. Mazzon, L. Dugo, A. Ciccolo, F.A.J. Van de Loo, A.P. Caputi, C. Thiemermann, S. Cuzzocrea. Twenty-Fourth Annual Conference on Shock, Marco Island, Florida 9-12 Giugno 2001. Shock 15: Abs. 210, 2001

127) EFFECTS OF N-ACETYLCYSTEINE, A RADICAL SCAVENGER, ON LUNG INJURY AND RED BLOOD CELL MODIFICATION INDUCED BY CARRAGEENAN IN THE RAT. L. Dugo, E. Mazzon, A.P. Caputi, S. Cuzzocrea. Twenty-Fourth Annual Conference on Shock, Marco Island, Florida 9-12 Giugno 2001. Shock 15: Abs. 224, 2001

128) HUMAN RECONSTITUTED HIGH-DENSITY LIPOPROTEIN ATTENUATES THE MULTIPLE ORGAN INJURY AND DYSFUNCTION IN HEMORRHAGIC SHOCK. M.C. McDonald, H. Mota-Filipe, G.W. Cockerill, S. Cuzzocrea, N.E. Miller, C. Thiemermann. Twenty-Fourth Annual Conference on Shock, Marco Island, Florida 9-12 Giugno 2001. Shock 15: Abs. 245, 2001

129) INDUCIBLE NITRIC OXIDE SYNTHASE REGULATE THE INITIATION OF THE INFLAMMATORY RESPONSE AFTER POTISCHEMIC INJURY. S. Cuzzocrea, L. Dugo, E. Mazzon, A. De Sarro, A.P. Caputi, C. Thiemermann.3rd Meeting of the Federation of the European Pharmacological Societies (EPHAR), Lione, Francia, 6-9 Luglio 2001. Fundamental and Clinical Pharmacology, 15: Abs. 8P146, 2001.

130) EFFECTS OF GPI 6150, AN INHIBITOR OF POLY(ADP-RIBOSE) POLYMERASE IN A RAT MODEL OF SPLANCHNIC ARTERY OCCLUSION AND REPERFUION. L. Dugo, E. Mazzon, A. De Sarro, J. Li, A.P. Caputi, J. Zhang, S. Cuzzocrea. 3rd Meeting of the Federation of the European Pharmacological Societies (EPHAR), Lione, Francia, 6-9 Luglio 2001. Fundamental and Clinical Pharmacology, 15: Abs. 8P147, 2001.

131) PHARMACOLOGICAL MANIPULATION OF THE INFLAMMATORY CASCADE BY THE SUPEROXIDE DISMUTASE MIMETIC, M40403. S. Cuzzocrea, E. Mazzon, L. Dugo, D.P. Riley, I. Serraino, A.P. Caputi, D. Salvemini. 3rd Meeting of the Federation of the European Pharmacological Societies (EPHAR), Lione, Francia, 6-9 Luglio 2001. Fundamental and Clinical Pharmacology, 15: Abs. 8P205, 2001.

132) ABSENCE OF ENDOGENOUS INTERLEUKIN-6 ENHANCES THE INFLAMMATORY RESPONSE DURING ACUTE PANCREATITIS IN MICE. E. Mazzon, L. Dugo, R. Di Paola, T. Genovese, A.P. Caputi, S. Cuzzocrea.Twenty-Fifth Annual Conference on Shock, Big Sky, Montana, U.S.A. Giugno 8-11, 2002. Shock 17, Abs. 55, 2002.

133) THE PPAR-γ LIGAND 15-DEOXY∆12,14PGJ2 ATTENUATES THE DEVELOPMENT

OF INTESTINAL ISCHEMIA/REPERFUSION.B. Pisano, A. Ianaro, E. Mazzon, L. Dugo, R. Di Paola, T. Genovese, A.P. Caputi, S. Cuzzocrea.Twenty-Fifth Annual Conference on Shock, Big Sky, Montana, U.S.A. Giugno 8-11, 2002. Shock 17, Abs. 144, 2002.

134) BENEFICIAL EFFECTS OF SUPEROXIDE DISMUTASE MIMETICS THE MULTIPLE ORGAN FAILURE INDUCED BY ZYMOSAN IN THE RAT. S. Cuzzocrea, R. Di Paola, T. Genovese, L. Dugo, I. Serraino, A.P. Caputi, D. Salvemini.Twenty-Fifth Annual Conference on Shock, Big Sky, Montana, U.S.A. Giugno 8-11, 2002. Shock 17, Abs. 185, 2002.

135) THE TYROSIN KINASE INHIBITOR TYRPHOSTIN AG126 REDUCES THE MULTIPLE ORGAN FAILURE INDUCED BY ZYMOSAN IN THE RAT. L. Dugo, P.K. Chatterjee, E. Mazzon, M.C. McDonald, R. Di Paola, F. Fulia, A.P. Caputi, C. Thiemermann, S. Cuzzocrea.Twenty-Fifth Annual Conference on Shock, Big Sky, Montana, U.S.A. Giugno 8-11, 2002. Shock 17, Abs. 186, 2002.

136) ANTIOXIDANT ACTIVITY OF CYANIDIN-3-O-GLUCOSIDE ON THE ENDOTHELIAL DYSFUNCTION IN CELLS AND IN VASCULAR RINGS EXPOSED TO PEROXYNITRITE. I. Serraino, L. Dugo, P. Dugo, L. Mondello, G. Dugo, A.P. Caputi, S. Cuzzocrea.Twenty-Fifth Annual Conference on Shock, Big Sky, Montana, U.S.A. Giugno 8-11, 2002. Shock 17, Abs. 201, 2002.

137) BENEFICIAL EFFECTS OF SUPEROXIDE DISMUTASE MIMETICS THE MULTIPLE ORGAN FAILURE INDUCED BY ZYMOSAN IN THE RAT. S. Cuzzocrea, R. Di Paola, T. Genovese, L. Dugo, I. Serraino, A.P. Caputi, D. Salvemini.Tenth Congress of the European Shock Society, Oslo, Norway. Settembre 5-7, 2002. Shock 18, Abs. 11, 2002.

138) PPAR-γ LIGANDS ATTENUATE THE DEVELOPMENT OF INTESTINAL ISCHEMIA/REPERFUSION. L. Dugo, B. Pisano, E. Mazzon, A.P. Caputi, S. Cuzzocrea.Tenth Congress of the European Shock Society, Oslo, Norway. Settembre 5-7, 2002. Shock 18, Abs. 15, 2002.

139) ABSENCE OF ENDOGENOUS INTERLEUKIN-6 ENHANCES THE INFLAMMATORY RESPONSE DURING ACUTE PANCREATITIS INDUCED BY CERULEIN IN MICE. T. Genovese, E. Mazzon, L. Dugo, R. Di Paola, A.P. Caputi, S. Cuzzocrea.Tenth Congress of the European Shock Society, Oslo, Norway. Settembre 5-7, 2002. Shock 18, Abs. 19, 2002.

140) BENEFICIAL EFFECTS OF GW274150, A NOVEL, POTENT AND SELECTIVE

INHIBITOR OF iNOS ACTIVITY, IN A RODENT MODEL OF COLLAGEN-INDUCED ARTHRITIS. R. Di Paola, S. Cuzzocrea, I. Serraino.VI Seminario Nazionale per Dottorandi in Farmacologia e Scienze Affini, Certosa di Pontignano, Siena, Italia. Settembre 23-26, 2002. Società Italiana di Farmacologia, Atti del Congresso, pag.145, 2002.

141) EFFECTS OF CALPAIN INHIBITOR I ON THE MULTIPLE ORGAN FAILURE INDUCED BY ZYMOSAN IN THE RAT.T. Genovese, S. Cuzzocrea, I. Serraino.VI Seminario Nazionale per Dottorandi in Farmacologia e Scienze Affini, Certosa di Pontignano, Siena, Italia. Settembre 23-26, 2002. Società Italiana di Farmacologia, Atti del Congresso, pag.141, 2002.

142) PPAR-γ LIGANDS ATTENUATE THE DEVELOPMENT OF INTESTINAL ISCHEMIA/REPERFUSION.L. Dugo, S. Cuzzocrea.VI Seminario Nazionale per Dottorandi in Farmacologia e Scienze Affini, Certosa di Pontignano, Siena, Italia. Settembre 23-26, 2002. Società Italiana di Farmacologia, Atti del Congresso, pag.106, 2002.

143) ROLE OF INDUCIBLE NITRIC OXIDE SYNTHASE IN THE INITIATION OF THE INFLAMMATORY RESPONSE AFTER POSTISCHEMIC INJURY.T. Genovese, L. Dugo, R. Di Paola, E. Mazzon, A. De Sarro, A.P. Caputi, S. Cuzzocrea.VIII Convegno Nazionale “Aspetti Biologici dell’Ossido di Azoto”, Certosa di Pontignano, Siena, Italia. Ottobre 6-8, 2002. Atti del Congresso, 2002.

144) ROLE OF NITRIC OXIDE ON PROSTAGLANDIN BIOSYNTHESIS.T. Genovese, L. Dugo, R. Di Paola, E. Mazzon, A. De Sarro, A.P. Caputi, S. Cuzzocrea.VIII Convegno Nazionale “Aspetti Biologici dell’Ossido di Azoto”, Certosa di Pontignano, Siena, Italia. Ottobre 6-8, 2002. Atti del Congresso, 2002.

145) EFFECTS OF GW274150, A NOVEL, POTENT AND SELECTIVE INHIBITOR OF iNOS ACTIVITY, IN A RODENT MODEL OF COLLAGEN-INDUCED ARTHRITIS.R. Di Paola, T. Genovese, E. Mazzon, L. Dugo, I. Serraino, A.P. Caputi, S. Cuzzocrea.VIII Convegno Nazionale “Aspetti Biologici dell’Ossido di Azoto”, Certosa di Pontignano, Siena, Italia. Ottobre 6-8, 2002. Atti del Congresso, 2002.

146) EFFETTI PROTETTIVI DELLE ANTOCIANINE ESTRATTE DAL SUCCO DI MORA IN UN MODELLO DI INFIAMMAZIONE POLMONARE ACUTA NEL RATTO.I. Serraino, A. Rossi, P. Dugo, R. Di Paola, L. Mondello, T. Genovese, D. Morabito, G. Dugo, L. Sautebin, A.P. Caputi, S. Cuzzocrea.XV Congresso Nazionale, Catania, Italia. Novembre 28-30, 2002. Associazione Italiana di Immunofarmacologia. Atti del Congresso, pag.83, 2002.

147) RUOLO DELLA 5-LIPOSSIGENASI NEL DANNO POLMONARE INDOTTO DA

CARRAGENINA NEL TOPO.A. Rossi, I. Serraino, R. Di Paola, L. Dugo, T. Genovese, B. Calabrò, A.P. Caputi, S. Cuzzocrea, L. Sautebin.XV Congresso Nazionale, Catania, Italia. Novembre 28-30, 2002. Associazione Italiana di Immunofarmacologia. Atti del Congresso, pag.80, 2002.

148) LA PROSTAGLANDINA 15-DEOSSI12,14-PGJ2, RIDUCE LA SEVERITA’ DEL DANNO AL COLON INDOTTO DALL’ACIDO DINITROBENZEN SULFORICO NEL RATTO.A. Ianaro, S. Cuzzocrea, E. Mazzon, B. Pisano, L. Dugo, I. Serraino, R. Di Paola, M. Di Rosa, A.P. Caputi,.XV Congresso Nazionale, Catania, Italia. Novembre 28-30, 2002. Associazione Italiana di Immunofarmacologia. Atti del Congresso, pag.68, 2002.

149) RUOLO DELLA INTERLEUCHINA-6 NELLA PANCREATITE ACUTA INDOTTA DA CERULEINA NEL TOPO.T. Genovese, I. Serraino, L. Dugo, R. Di Paola, A.P. Caputi, S. Cuzzocrea.XV Congresso Nazionale, Catania, Italia. Novembre 28-30, 2002. Associazione Italiana di Immunofarmacologia. Atti del Congresso, pag.67, 2002.

150) RUOLO DELLA INTERLEUCHINA-10 NEL DANNO POLMONARE ACUTO INDOTTO DA CARRAGENINA.R. Di Paola, T. Genovese, L. Dugo, I. Serraino, A.P. Caputi, S. Cuzzocrea.XV Congresso Nazionale, Catania, Italia. Novembre 28-30, 2002. Associazione Italiana di Immunofarmacologia. Atti del Congresso, pag.64, 2002.

151) RUOLO DELLA PROSTAGLANDINA 15-DEOSSI12,14-PGJ2, LIGANDO DEL PPAR-γ, NELL’INFIAMMAZIONE ACUTA E CRONICA.S. Cuzzocrea, L. Dugo, I. Serraino, R. Di Paola, T. Genovese, A.P. Caputi.XV Congresso Nazionale, Catania, Italia. Novembre 28-30, 2002. Associazione Italiana di Immunofarmacologia. Atti del Congresso, pag.26, 2002.

152) ROLE OF INTERLEUKIN-10 IN ACUTE AND CHRONIC INFLAMMATION Cuzzocrea S, Dugo L, Serraino I, Genovese T, Di Paola R, Caputi APProceedings Of The British Parmacological Society, Metropole Brighton, Brighton, UK, January 8th-10th, 2003

153) ROLE OF PPAR-G LIGAND ROSIGLITAZONE ON THE DEVELOPMANT OF CARRAGEENAN INDUCED LUNG INJURYCuzzocrea S, Dugo L, Di Paola R, Serraino I, Genovese T, Caputi AP, Thiemermann CProceedings Of The British Parmacological Society, Metropole Brighton, Brighton, UK, January 8th-10th, 2003

154) ATTENUATE THE DEVELOPMENT OF INTESTINAL ISCHEMIA/REPERFUSION PPAR-γ LIGANDS

Dugo L, Pisano B, Wayman N, Ianaro A, Mazzon E, Caputi AP, Thiemermann C, Cuzzocrea S

Proceedings Of The British Parmacological Society, Metropole Brighton, Brighton, UK, January 8th-10th, 2003

155) ROLE OF THE INDUCIBLE NITRIC OXIDE SYNTHASE IN EXPERIMENTAL MODEL OF ACUTE PANCREATITISS.Cuzzocrea, L. Dugo, I. Serraino, T. Genovese, R. Di Paola, D. Britti, A.P. Caputi, C.ThiemermannJoint Meeting of the Italian and Dutch Pharmacological Societies, Lunteren, Olanda. Febbraio 12-14, 2003.

156) ROLE OF PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR-γ (PPAR-γ) LIGANDS THE DEVELOPMENT OF ACUTE AND CHRONIC INFLAMMATION.S. Cuzzocrea, L. Dugo, R. Di Paola, I. Serraino, T. Genovese, A.P. Caputi.Joint Meeting of the Italian and Dutch Pharmacological Societies, Lunteren, Olanda. Febbraio 12-14, 2003.

157) ANTI-INFLAMMATORY ACTIVITY OF METHYLGUANIDINE ON CARRAGEENAN INDUCED RAT PLEURISYS.Marzocco, I. Serraino, S. Cuzzocrea, R. Sorrentino, A. Pinto and G. AutoreJoint Meeting of the Italian and Dutch Pharmacological Societies, Lunteren, Olanda. Febbraio 12-14, 2003.

158) PYRROLIDINE DITHIOCARBAMATE MODULATES THE SEVERITY OF CERULEIN INDUCED MURINE ACUTE PANCREATITIS.I. Serraino, I. Virlos, E. Mazzon, R. Di Paola, T. Genovese, D. Britti, C. Thiemermann, A. Siriwardena, S. Cuzzocrea.Joint Meeting of the Italian and Dutch Pharmacological Societies, Lunteren, Olanda. Febbraio 12-14, 2003.

159) ROLE OF PPAR-γ LIGAND ROSIGLITAZONE ON THE DEVELOPMENT OF EXPERIMENTAL ACUTE PANCREATITISS. Cuzzocrea, L. Dugo, B. Pisano, A. Ianaro, R. Di Paola, T. Genovese, I. Serraino, A.P. Caputi, C. Thiemermann.Second International Symposium on PPARs: From Basic Science to Clinical Applications, Florence, Italy-March 19-22, 2003

160) ROLE OF PPAR-γ LIGAND ROSIGLITAZONE ON THE DEVELOPMENT OF CARRAGEENAN-INDUCED LUNG INJURY S. Cuzzocrea, L. Dugo, R. Di Paola, I. Serraino, T. Genjovese, A.P. Caputi, C. Thiemermann. Second International Symposium on PPARs: From Basic Science to Clinical Applications, Florence, Italy-March 19-22, 2003

161) ROLE OF PPAR- γ LIGANDS ATTENUATE THE DEVELOPMENT OF INTESTINAL ISCHEMIA/REPERFUSIONL. Dugo, B. Pisano, N.Wayman, A. Ianaro, E. Mazzon, A.P. Caputi, C. Thiemermann, S. Cuzzocrea

Second International Symposium on PPARs: From Basic Science to Clinical Applications, Florence, Italy-March 19-22, 2003

162) EFFECT OF 5-AMINOISOQUINOLINONE, A WATER SOLUBLE, POTENT INHIBITOR OF THE ACTIVITY OF POLY(ADP-RIBOSE)POLYMERASE, IN A RODENT MODEL OF LUNG INJURYDugo L, Cuzzocrea S, McDonald MG, Mazzon E, Serraino I, Threadgill M, Caputi AP, Thiemermann CPARP-2003, Lisbon, Portugal, May 2nd-5th, 2003

163) ROLE OF POLY(ADP-RIBOSE)POLYMERASE IN ISCHEMIA-REPERFUSION INJURY OF THE INTESTINECuzzocrea SPARP-2003, Lisbon, Portugal, May 2nd-5th, 2003

164) PREVENTION OF ANTIGEN-INDUCED BRONCHOCONSTRICTION BY OF POLY(ADP-RIBOSE)POLYMERASE INHIBITORS IN ACTIVELY SENSITIZED GUINEA PIGSMasini E, Suzuki Y, Pierpaoli S, Cuzzocrea S, Bani D, Suzuki HPARP-2003, Lisbon, Portugal, May 2nd-5th, 2003

165) PYRROLIDINE DITHIOCARBAMATE ATTENUATES THE DEVELOPMENT OF ORGAN FAILURE INDUCED BY ZYMOSAN IN MICEDi Paola R, Genovese T, Patel NSA, Chatterjee PK, Caputi AP, Thiemermann C, Cuzzocrea STwenty-Sixth Annual Conference on Shock, Phoenix, Arizona, June 7th-10th, 2003

166) INDUCIBLE NITRIC OXIDE SYNTHASE-DEFICIENT MICE EXHIBIT RESISTANCE TO THE ACUTE PANCREATITIS INDUCED BY CERULEINDugo L, Mazzon E, Serraino I, Caputi Ap, Thiemermann C, Cuzzocrea STwenty-Sixth Annual Conference on Shock, Phoenix, Arizona, June 7th-10th, 2003

169) PPAR-gamma LIGANDS REDUCED THE DEVELOPMENT OF INTESTINAL ISCHEMIA/REPERFUSIONS.Cuzzocrea, Dugo L, Pisano B, Wayman N, Ianaro A, Mazzon E, Caputi AP, Thiemermann CTwenty-Sixth Annual Conference on Shock, Phoenix, Arizona, June 7th-10th, 2003

170) IN VITRO EFFECT OF A PEPTIDE ACTIVATING PAR2(PAR2-AP) ON AIRWAYS OF LPS-TREATED RATSCicala C, Morello S, Maffia P, Cuzzocrea S, Roviezzo F, Cirino G.31° Congresso Nazionale della Società Italiana di Farmacologia, Trieste, Giugno 26-29, 2003

171) PROTECTIVE EFFECTS OF M40401, A SELECTIVE SUPEROXIDE DISMUTASE MIMETIC, ON THE MULTIPLE ORGAN FAILURE INDUCED BY ZIMOSAN IN THE RATCuzzocrea S, Mazzon E, Di Paola R, Genovese T, Serraino I, Dugo L, Caputi AP, Salvemini D31° Congresso Nazionale della Società Italiana di Farmacologia, Trieste, Giugno 26-29, 2003

172) ROSIGLITAZONE A LIGANDS OF THE PEROXISOME PROLIFERATOR-ACTRIVATED RECEPTOR-γ (PPAR-γ), REDUCE THE EVOLUTION OF MURINE TYPE II COLLAGEN-INDUCED ARTHRITISCuzzocrea S, Mazzon E, Dugo L, Patel N, Serraino I, Di Paola R, Genovese T, Britti D,. Caputi AP, Thiemermann C31° Congresso Nazionale della Società Italiana di Farmacologia, Trieste, Giugno 26-29, 2003

173) MELATONIN REVERTS THE LIPOPOLYSACCAHARIDE (LPS) INDUCED HIPOREACTIVITY IN A VIVO AND IN VITRO MODEL IN RATd’Emmanuele di Villa Bianca R, Cuzzocrea S, Serraino I, Marzocco S, Autore G, Pinto A, Sorrentino R.31° Congresso Nazionale della Società Italiana di Farmacologia, Trieste, Giugno 26-29, 2003

174) PYRROLIDINE DITHIOCARBAMATE MODULATES THE SEVERITY OF CERULEIN INDUCED MURINE ACUTE PANCREATITISDe Sarro A, Virlos I, Mazzon E, Serraino I, Di Paola R, Genovese T, Britti D, Thiemermann C, Siriwardena A, Cuzzocrea S31° Congresso Nazionale della Società Italiana di Farmacologia, Trieste, Giugno 26-29, 2003

175) PREVENTION OF ANTIGEN-INDUCED BRONCHOCOSTRICTION BY INHIBITION OF (ADP-RIBOSE)POLYMERASE, IN ACTIVELY SENSITIZED GUINEA PIGSDi Felice A, Pierpaoli S, Vannacci A, Giannini L, Marzocca C, Zagli G, Mannaioni PF, Suzuki H, Cuzzocrea S, Bani D, Masini E31° Congresso Nazionale della Società Italiana di Farmacologia, Trieste, Giugno 26-29, 2003

176) BENEFICIAL EFFECTS OF 5-AMINOISOQUINOLINONE, A NOVEL, POTENT, WATER-SOLUBLE, INHIBITOR OF POLY(ADP-RIBOSE)POLYMERASE, IN A RAT MODEL OF SPLANCHNIC ARTERY OCCLUSION AND REPERFUSIONDi Paola R, Genovese T, Serraino I, Dugo L, De Sarro A, Caputi AP, Cuzzocrea S31° Congresso Nazionale della Società Italiana di Farmacologia, Trieste, Giugno 26-29, 2003

177) ROSIGLITAZONE AND 15-DEOXY-∆12,14-PROSTAGLANDIN J2, LIGANDS OF THE PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR-γ (PPAR-γ), REDUCE ISHEMIA/REPERFUSION INJURY OF THE GUTDugo L, Pisano B, Ianaro A, Patel NSA, Di Paola R, Genovese T, Chatterjee PK, Di Rosa M, Caputi AP, Thiemermann C, Cuzzocrea S31° Congresso Nazionale della Società Italiana di Farmacologia, Trieste, Giugno 26-29, 2003

178) PYRROLIDINE DITHIOCARBAMATE (PDTC) REDUCES NEURONAL DAMAGE AFTER SPINAL CORD INJURY IN RATSGenovese T, Di Paola R, Cardali S, Conti A, Cuzzocrea S, Caputi AP.31° Congresso Nazionale della Società Italiana di Farmacologia, Trieste, Giugno 26-29, 2003

179) THE EFFECT OF PROSTAGLANDIN J2 AND 2-CYCLOPENTEN-1-ONE ON RESTENOSIS IN A RAT MODEL OF ANGIOPLASTYIalenti A, Ianaro A, Maffia P, Grassia G, Cuzzocrea S, Santoro MG, Di Rosa M

31° Congresso Nazionale della Società Italiana di Farmacologia, Trieste, Giugno 26-29, 2003

180) EFFECT OF METHYLGUANIDINE ON CARRAGEENAN-INDUCED LUNG INJURYMarzocco S, Serraino I, Cuzzocrea S, Sorrentino R, Pinto A, Autore G.31° Congresso Nazionale della Società Italiana di Farmacologia, Trieste, Giugno 26-29, 2003

181) CALPAIN INHIBITOR I REDUCES ISCHEMIA AND REPERFUSION-INDUCED INTESTINAL INJURYMarzocco S, Di Paola R, Autore G, Serraino I, De Sarro A, Pinto A, Caputi AP, Cuzzocrea S.31° Congresso Nazionale della Società Italiana di Farmacologia, Trieste, Giugno 26-29, 2003

182) 5-LIPOXYGENASE KNOCKOUT MICE EXHIBIT A RESISTANCE TO SPLANCHNIC ARTERY OCCLUSION (SAO) SHOCKRossi A, Cuzzocrea S, Serraino I, Di Paola R, Genovese T, Caputi AP, Sautebin L.31° Congresso Nazionale della Società Italiana di Farmacologia, Trieste, Giugno 26-29, 2003

183) ROLE OF 5-LIPOXYGENASE IN THE MULTIPLE ORGAN FAILURE INDUCED BY ZYMOSANSautebin L, Cuzzocrea S, Rossi A, Serraino I, Di Paola R, Britti D, Caputi AP.31° Congresso Nazionale della Società Italiana di Farmacologia, Trieste, Giugno 26-29, 2003

184) ANTIOXIDANT AND ANTINFLAMMATORY EFFECT OF CYANIDIN-3-O-GLUCOSIDE FROM BLACKBERRY EXTRACTSerraino I., Rossi Antonietta, Paola Dugo, Rosanna Di Paola, Luigi Mondello, Tiziana Genovese, Morabito D, Dugo G, Sautebin L, Caputi A P, Cuzzocrea S.31° Congresso Nazionale della Società Italiana di Farmacologia, Trieste, Giugno 26-29, 2003

185) MELATONIN IMPROVES BEHAVIOURAL RESPONSE ON FORCED SWIMMING TEST AND DECREASE NEURONAL DAMAGE AFTER PARAQUAT TREATMENT IN TWO MICE STRAINS Trombetta G, Arbitrio M, Costa N, Cuzzocrea S, Marra R, De Sarro G, Rotiroti D.31° Congresso Nazionale della Società Italiana di Farmacologia, Trieste, Giugno 26-29, 2003

186) ANTIOXIDANT AND ANTI-INFLAMMATORY EFFECTS OF CYANIDIN-3-O-GLUCOSIDE FROM BLACKBERRY EXTRACTSerraino I, Rossi A, Dugo P, Di Paola R, Mondello L, Genovese T, Morabito D, Dugo G, Sautebin L, Caputi AP, Cuzzocrea S.3rd International Symposium on Natural Drugs, Naples, Italy, 2nd-4th,2003

187) ANTI-INFLAMMATORY EFFECT OF YUCCA SCHIDIGERA ROEZL DERIVED COMPOUNDS ON LPS-STIMULATED J774.A1MACROPHAGES.Marzocco S, Cuzzocrea S, Piacente S, Pizza C, Oleszek W, Stochmal A, Sorrentino R, Pinto, Autore G.3rd International Symposium on Natural Drugs, Naples, Italy, 2nd-4th,2003

188) INHIBITORY EFFECTS OF A BLACKBERRY EXTRACT ON THE CIRCULATORY FAILURE AND ORGAN DYSFUNCTION CAUSED BY ENDOTOXIN IN THE RATSautebin L, Rossi A, Serraino I, Dugo P, Di Paola R, Mondello L, Morabito D, Caputi AP Cuzzocrea S3rd International Symposium on Natural Drugs, Naples, Italy, 2nd-4th,2003

189) EFFECT OF METHYLGUANIDINE IN A MODEL OF SEPTIC SHOCK INDUCED BYLPSMarzocco S, Di Paola R, Britti D, Pinto A, Sorrentino R, Cuzzocrea S, Autore G.Aspetti biologici dell’ossido di azoto IX Convegno Nazionale, Certosa di Pontignano-Siena, Italia, 13-15 Ottobre 2003

190) INHIBITION OF THE NUCLEAR FACTOR-KB ACTIVATION WITH PYRROLIDINEDITHIOCARBAMATE ATTENUATES INFLAMMATION AND OXIDATIVE STRESS AFTER EXPERIMENTAL SPINAL CORD TRAUMA IN RATSGenovese T, Cardali S, Conti A, Di Paola R, Cuzzocrea S.Aspetti biologici dell’ossido di azoto IX Convegno Nazionale, Certosa di Pontignano-Siena, Italia, 13-15 Ottobre 2003

191) iNOS MEDIATES BONE LOSS IN OVARIECTOMIZED MICECuzzocrea S, Mazzon E, Dugo L, Genovese T, Di Paola R, Vegeto E, Caputi AP, Maggi AAspetti biologici dell’ossido di azoto IX Convegno Nazionale, Certosa di Pontignano-Siena, Italia, 13-15 Ottobre 2003

192) EFFECT OF AMINOGUANIDINE IN LIGATURE-INDUCED PERIODONTITIS IN THERATSDi Paola R, Marzocco S, Mazzon E, Dattola F, Rotondo F, Britti D, De Maio M, Genovese T, Cuzzocrea SAspetti biologici dell’ossido di azoto IX Convegno Nazionale, Certosa di Pontignano-Siena, Italia, 13-15 Ottobre 2003

193) ROLE OF POLY(ADP-RIBOSE) POLYMERASE IN ISCHEMIA-REPERFUSIONINJURY OF THE INTESTINE S. Cuzzocrea 6th World Congress on Trauma, Shock, Inflammation and Sepsis in conjunction with the 5 th

International Congress on Shock. March 2nd – 6th, 2004 Munich, Germany. Abstract book pp:91

194) CALPAIN INHIBITOR I REDUCES INTESTINAL ISCHEMIA-REPERFUSIONINJURY IN THE RATR. Di Paola S. Marzocco, G. Autore, A. Pinto, A.P. Caputi, C. Thiemmermann S. Cuzzocrea6th World Congress on Trauma, Shock, Inflammation and Sepsis in conjunction with the 5 th

International Congress on Shock March 2nd – 6th, 2004 Munich, Germany. Abstract book pp 92

195) ROSIGLITAZONE, A LIGAND OF THE PEROXISOME PROLIFERATORACTIVATED RECEPTOR-GAMMA (PPAR-Γ) REDUCES THE DEVELOPMENT OF NON SEPTIC SHOCK INDUCED BY ZYMOSAN IN MICE

S. Cuzzocrea, L. Dugo, N.S.A. Patel, R. Di Paola, T. Genovese, P.K. Chatterjee, A.P. Caputi C. Thiemermann 6th World Congress on Trauma, Shock, Inflammation and Sepsis in conjunction with the 5 th

International Congress on Shock March 2nd – 6th, 2004 Munich, Germany. Abstract book pp. 128.

196) PYRROLIDINE DITHIOCARBAMATE REDUCED SPINAL CORD TRAUMA INRATS Genovese, S. Cardali, A. Conti, R. Di Paola, S. Cuzzocrea.6th World Congress on Trauma, Shock, Inflammation and Sepsis in conjunction with the 5 th

International Congress on Shock March 2nd – 6th, 2004 Munich, Germany. Abstract book pp27

197) ROLE OF SUPEROXIDE ANION IN SEPTIC AND NON SEPTIC SHOCK Cuzzocrea S.German Italian Villa Vigoni Conference on Redox Regulation in Disease and Ageing March 24-27, 20004

198) ROLE OF PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR-γ (PPAR-γ)LIGANDS: THE DEVELOPMENT OF ACUTE AND CHRONIC INFLAMMATIONCuzzocrea S. Dugo L. Di Paola R, Genovese T, Caputi AP and Christoph ThiemermannOne Day Meeting Organised By GREMI PPAR α/β/γ and Inflammation paris, Pasteur Institute, March 26, 2004

199) ESTROGENS AND INFLAMMATION Cuzzocrea S.5th International Symposium on Women’s Health and Menopause new Findings, new Strategies, Iimproved Quality of Life. Florence Italy April 21-24, 2004

200) INHIBITION OF IΚB BY CALPAIN-1 INHIBITOR AMELIORATES THE INDICESOF MURINE CERULEIN-INDUCED ACUTE PANCREATITIS. Virlos IT, Serraino I, Mazzon E, Thiemermann C, Siriwardena AK, Cuzzocrea S. Selective Presented at the Annual meeting of the American Gastroenterology Association, New Orleans, LA, May 17th 2004. (abstract in Gastroenterology)

201) INHIBITION OF IΚB BY CALPAIN-1 INHIBITOR AMELIORATES THE INDICESOF MURINE CERULEIN-INDUCED ACUTE PANCREATITIS. Virlos IT, Serraino I, Mazzon E, Thiemermann C, Siriwardena AK, Cuzzocrea S. Selective Presented at the 6th World Congress of the International HepatoPancreatoBiliary Association, Washington DC, 5th June 2004. (abstract in HPB).

202) REDUCTION IN THE DEVELOPMENT OF CERULEIN-INDUCED ACUTEPANCREATITIS BY TREATMENT WITH M40401, A NEW SELECTIVE SUPEROXIDE DISMUTASE MIMETIC. S. Cuzzocrea, T. Genovese, E. Mazzon, R. Di Paola, C. Muià, D. Britti, D. Salvemini11th Congress of the European Shock Society Vienna, Austria January 27-30, 2005SHOCK 23, abst 40, 2005

203) BENEFICIAL EFFECTS OF 5-AMINOISOQUINOLINONE, A NOVEL, POTENT,WATER-SOLUBLE, INHIBITOR OF THE OF POLY (ADP-RIBOSE) POLYMERASE, IN A RAT MODEL OF SPLANCHNIC ARTERY OCCLUSION AND REPERFUSIONR. Di Paola, T. Genovese, A.P. Caputi, M. Threadgill, C. Thiemermann, S. Cuzzocrea11th Congress of the European Shock Society Vienna, Austria January 27-30, 2005SHOCK 23, abst 43, 2005

204) INHIBITORS OF POLY (ADP-RIBOSE) POLYMERASE MODULATE SIGNAL TRANSDUCTION PATHWAYS AND SECONDARY DAMAGE IN EXPERIMENTAL SPINAL CORD TRAUMA. T. Genovese, E. Mazzon, C. Muià, N.S.A. Patel, M.D. Threadgill, P. Bramanti, A. De Sarro, C. Thiemermann, S. Cuzzocrea.11th Congress of the European Shock Society Vienna, Austria January 27-30, 2005SHOCK 23, abst 56, 2005

205) WY 14643, A POTENT EXOGENOUS PPAR-α LIGAND REDUCES INTESTINAL INJURY ASSOCIATED WITH SPLANCHNIC ARTERY OCCLUSION (SAO) SHOCK.S. Cuzzocrea, R. Di Paola, E. Mazzon, T. Genovese, C. Muià, A.P. Caputi11th Congress of the European Shock Society Vienna, Austria January 27-30, 2005SHOCK 23, abst 121, 2005

206) ROSIGLITAZONE AND 15-DEOXY-12,14-PROSTAGLANDIN J2, LIGANDS OF THE PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR-γ (PPAR-γ), REDUCE ISCHAEMIA/REPERFUSION INJURY OF THE GUTS. Cuzzocrea, B. Pisano, L. Dugo, A. Ianaro, N.S.A. Patel, R. Di Paola, T. Genovese, P.K. Chatterjee, M. Di Rosa, A.P. Caputi, C. Thiemermann11th Congress of the European Shock Society Vienna, Austria January 27-30, 2005SHOCK 23, abst 120, 2005

207) MICE LACKING THE 110KDA ISOFORM OF POLY (ADP-RIBOSE ) GLYCOHYDROLASE ARE PROTECTED AGANIST RENAL ISCHEMIA REPERFUSION INJURY.E. Mazzon, N.S.A. Patel, C. Thiemermann, S. Cuzzocrea, R. Di Paola, U. Cortes, Z.Q. Wang, H-M Filipe. 11th Congress of the European Shock Society Vienna, Austria January 27-30, 2005SHOCK 23, abst 117, 2005

208) 15-DEOXY-∆12,14-PROSTAGLANDIN J2, REDUCES THE MULTIPLE ORGAN FAILURE CAUSED BY WALL-FRAGMENT OF GRAM-POSITIVE AND GRAM-NEGATIVE BACTERIA.L. Dugo, M. Collins, S. Cuzzocrea, C. Thiemermann 11th Congress of the European Shock Society Vienna, Austria January 27-30, 2005SHOCK 23, abst 148, 2005

209) MELATONIN LIMITS LUNG INJURY IN BLEOMYCIN TRETED MICE. T. Genovese, R. Di Paola, E. Mazzon, C. Muià, A.P. Caputi, S. CuzzocreaTwenty-Eighth Annual Conference On Shock. Marco Island, Florida, USA June 4-7 2005.SHOCK 23, abst 192, 200532° Congresso Nazionale Della Società Italiana Di Farmacologia. Napoli, Italia 1-4 Giugno 2005

210) WY 14643, A POTENT EXOGENOUS PPAR- LIGAND REDUCES INTESTINAL INJURY ASSOCIATED WITH SPLANCHNIC ARTERY OCCLUSION (SAO) SHOCK.R. Di Paola, E. Mazzon, T. Genovese, C. Muià, A.P. Caputi, S. Cuzzocrea. 32° Congresso Nazionale Della Società Italiana Di Farmacologia. Napoli, Italia 1-4 Giugno 2005

211) GREEN TEA POLYPHENOL EXTRACT ATTENUATES ISCHAEMIA/REPERFUSION INJURY OF THE GUT. C. Muià, E. Mazzon, R. Di Paola, T. Genovese, M. Menegazzi, A.P. Caputi, H. Suzuki, S. Cuzzocrea 32° Congresso Nazionale Della Società Italiana Di Farmacologia. Napoli, Italia 1-4 Giugno 2005

212) GLUCOCORTICOID INDUCED TNF RECEPTOR FAMILY GENE (GITR) KNOCK OUT MICE EXHIBIT A RESISTANCE TO SPLANCHNIC ARTERY OCCLUSION (SAO) SHOCK. S. Cuzzocrea, G. Nocentini, R. Di Paola S. Ronchetti, E. Mazzon, R. Bianchini, T. Genovese, C. Muià, A.P. Caputi, C. Riccardi.32° Congresso Nazionale Della Società Italiana Di Farmacologia. Napoli, Italia 1-4 Giugno 2005

213) INHIBITORS OF POLY (ADP-RIBOSE) POLYMERASE MODULATE SIGNAL TRANSDUCTION PATHWAYS AND SECONDARY DAMAGE IN EXPERIMENTAL SPINAL CORD TRAUMA.T. Genovese, E. Mazzon, C. Muià, N.S.A. Patel, M.D. Thredgill, P. Bramanti, A. De Sarro, C. Thiemermann, S. Cuzzocrea.32° Congresso Nazionale Della Società Italiana Di Farmacologia. Napoli, Italia 1-4 Giugno 2005

214) EFFECT OF ROSIGLITAZONE AND 15-DEOXY-D12,14- PROSTAGLANDIN J2 ON BLEOMYCIN-INDUCED LUNG INJURY.S. Cuzzocrea, T. Genovese, R. Di Paola, C. Ma Struzzo, M. Sortino, N. Crimi, A.P. Caputi, C. Thiemermann, C. Vancheri.32° Congresso Nazionale Della Società Italiana Di Farmacologia. Napoli, Italia 1-4 Giugno 2005

215) INCREASED CARRAGEENAN-INDUCED ACUTE LUNG INFLAMMATION IN OLD RATS. E. Corsini, R. Di Paola, B. Viviani, T. Genovese, E. Mazzon, S. Bartesaghi, M. Marinovich, C.Cl.C, Galli, S. Cuzzocrea32° Congresso Nazionale Della Società Italiana Di Farmacologia. Napoli, Italia 1-4 Giugno 2005

216) ROLE OF GLUCOCORTICOID- INDUCED TNF RECEPTOR FAMILY GENE (GITR) IN COLLAGEN-INDUCED ARTHRITIS. S. Cuzzocrea, E. Ayroldi R. Di Paola, M. Agostini, E. Mazzon, S. Bruscoli, T. Genovese, S. Ronchetti, A.P. Caputi, C. Riccardi.

32° Congresso Nazionale Della Società Italiana Di Farmacologia. Napoli, Italia 1-4 Giugno 2005

217) UP-REGULATION OF PROSTAGLANDIN BIOSYNTHESIS BY LEUKOTRIENE C4 IN ELICITED MICE PERITONEAL MACROPHAGES ACTIVATED WITH PERITONEAL MACROPHAGES ACTIVATED WITH LIPOPOLYSACCHARIDE/INTERFERON-. A. Rossi, M.A. Acquaviva, F. Iuliano, C. Pergola, S. Cuzzocrea, L. Sautebin32° Congresso Nazionale Della Società Italiana Di Farmacologia. Napoli, Italia 1-4 Giugno 2005

218) ERYTHROPOIETIN REDUCES THE DEGREE OF ARTHRITIS CAUSED BY TYPE II COLLAGEN IN THE MOUSES. Cuzzocrea, E. Mazzon, R. Di Paola, T. Genovese, N.S.A. Patel, D. Britti, A.P. Caputi, C. Thiemermann32° Congresso Nazionale Della Società Italiana Di Farmacologia. Napoli, Italia 1-4 Giugno 2005

219) 5-AMINOISOQUINOLINONE REDUCES COLON INJURY BY EXPERIMENTAL COLITIS. A. De Sarro, E. Mazzon, R. Di Paola, T. Genovese, N.S.A. Patel, C. Muià, M.D. Threadgill, S. Cuzzocrea.32° Congresso Nazionale Della Società Italiana Di Farmacologia. Napoli, Italia 1-4 Giugno 2005

220) EFFECTS OF ANTHOCYANINS FROM BLACKBERRY EXTRACT ON NITRITE AND PROSTAGLANDIN PRODUCTION BY J774 MURINE MACROPHAGES STIMULATED WITH LIPOPOLYSACCHARIDE. C. Pergola, A. Rossi, P. Dugo, S. Cuzzocrea, L. Sautebin.32° congresso nazionale della società italiana di farmacologia. Napoli, Italia 1-4 giugno 2005

221) GREEN TEA POLYPHENOL EXTRACT ATTENUATES ISCHAEMIA/REPERFUSION INJURY OF THE GUT. C Muià, E. Mazzon, R. Di Paola, T. Genovese, M. Menegazzi, A.P. Caputi, H. Suzuki, S. CuzzocreaTwenty-Eighth Annual Conference On Shock. Marco Island, Florida, USA June 4-7 2005.SHOCK 23, abst 38, 2005

222) PARG ACTIVITY MEDIATES INTESTINAL INJURY INDUCED BY SPLANCHNIC OCCLUSION AND REPERFUSION. S. Cuzzocrea, R. Di Paola, E. Mazzon, U. Cortes, T.Genovese, C.Muià, W. Li, W. Xu, J.H. Li, J. Zhang, Z.Q. Wang.Twenty-Eighth Annual Conference On Shock. Marco Island, Florida, USA June 4-7 2005.SHOCK 23, abst 40, 2005

223) ROLE OF ENDOGENOUS LIGANDS FOR THE PEROXISOME PROLIFERATORS ACTIVATED RECEPTORS ALPHA IN THE SECONDARY DAMAGE IN EXPERIMENTAL SPINAL CORD TRAUMA.R. Di Paola, T. Genovese, E. Mazzon, G. Cannavò, C. Muià, P. Bramanti, S. CuzzocreaTwenty-Eighth Annual Conference On Shock. Marco Island, Florida, USA June 4-7 2005.SHOCK 23, abst 138, 2005

224) MICE LACKING THE 110 KDA ISOFORM OF POLY (ADP-RIBOSE) GLYCOHYDROLASE (PARG110) ARE PROTECTED AGAINST RENAL ISCHEMIA/REPERFUSION INJURY NSA Patel, U. Cortes, R. Di Paola, E. Mazzon, H. Mota Filipe, S. Cuzzocrea, Zhao-Qi Wang, C. ThiemermannPoly (ADP-Ribose) Polymerases: Bench to Bedside. October 5th-7th, 2005, Gateshead, United Kingdom.

225) INHIBITORS OF POLY (ADP-RIBOSE) POLYMERASE MODULATE SIGNAL TRANSDUCTION PATHWAYS AND SECONDARY DAMAGE IN EXPERIMENTAL SPINAL CORD TRAUMA. T. Genovese, E. Mazzon, C. Muià, NSA Patel , M.D Threadgill, P. Bramanti, A. De Sarro, C. Thiemermann, S. CuzzocreaPoly (ADP-Ribose) Polymerases: Bench to Bedside. October 5th-7th, 2005, Gateshead, United Kingdom.

226) PARG ACTIVITY MEDIATES INTESTINAL INJURY INDUCED BY ISCHEMIA AND REPERFUSION S Cuzzocrea, R Di Paola, E Mazzon, U Cortes, T Genovese C Muià, W Li, W Xu, JH Li, J Zhang, ZQ Wang .Poly (ADP-Ribose) Polymerases: Bench to Bedside. October 5th-7th, 2005, Gateshead, United Kingdom.

227) PARG ACTIVITY MEDIATES INTESTINAL INJURY INDUCED BY SPLANCHNIC ARTERY OCCLUSION AND REPERFUSION.Cuzzocrea S., Di Paola R., Mazzon E., Cortes U., Genovese T., Muià C., Li W., Xu W., Li J.H., Zhang J., Wang Z.Q.XIV Congresso Nazionale SITOX. Roma, Istituto Superiore di Sanità, 6-9 Febbraio 2006.

228) ROLE OF ENDOGENOUS AND EXOGENOUS LIGANDS FOR THE PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR ALPHA IN THE DEVELOPMENT OF BLEOMYCIN-INDUCED LUNG INJURY.Genovese T., Mazzon E., Di Paola R., Muià C., Crisafulli C., Caputi AP., Cuzzocrea S.XIV CONGRESSO NAZIONALE SITOX. ROMA, ISTITUTO SUPERIORE DI SANITÀ, 6-9 FEBBRAIO 2006.

229) ANTHOCYANINS, GREEN TEA AND HYPERICUM ESTRACT IN ACUTE AND CHRONIC INFLAMMATIONCuzzocrea s.XIV CONGRESSO NAZIONALE SITOX. ROMA, ISTITUTO SUPERIORE DI SANITÀ, 6-9 FEBBRAIO 2006.

230) GREEN TEA POLYPHENOL EXTRACT ATTENUATES LUNG INJURY IN EXPERIMENTAL MODEL OF CARRAGEENAN-INDUCED PLEURISY IN MICE

Muià C., Mazzon E., Di Paola R., Genovese T., Menegazzi M., Zaffini R., Suzuki H., Cuzzocrea S.XIV CONGRESSO NAZIONALE SITOX. ROMA, ISTITUTO SUPERIORE DI SANITÀ, 6-9 FEBBRAIO 2006.

231) MECHANISM OF THE ANTI-INFLAMMATORY EFFECT OF GLUCOCORTICOID : RELATIONSHIP WITH THE PPAR- α LIGAND PATHWAYCrisafulli C., Mazzon E., Muià C., Caputi A.P., Cuzzocrea S.XIV CONGRESSO NAZIONALE SITOX. ROMA, ISTITUTO SUPERIORE DI SANITÀ, 6-9 FEBBRAIO 2006.

232) GLYCOGEN SYNTHASE KINASE-3B INHIBITION REDUCES THE DEVELOPMENT OF NON SEPTIC SHOCK INDUCED BY ZYMOSAN IN MICE. S Cuzzocrea. R Di Paola, E Mazzon, C Crisafulli, T. Genovese, C Muià, E Esposito, M Abdelrahaman, C thiemermann. Twelfth Congress Of The European Shok Society, Ulm, Germany, September 14-16 2006.

233) GLYCOGEN SYNTHASE KINASE-3 INHIBITION REDUCES SECONDARY DAMAGE IN EXPERIMENTAL SPYNAL CORD TRAUMA. S Cuzzocrea. T. Genovese, E Mazzon, C Crisafulli, R Di Paola, C Muià, E Esposito, M Collin, P Bramanti, C thiemermann. TWELFTH CONGRESS OF THE EUROPEAN SHOK SOCIETY, ULM, GERMANY, SEPTEMBER 14-16 2006.

234) PARG ACTIVITY MEDIATES POST-TRAUMATIC INFLAMMATORY REACTION AFTER EXPERIMENTAL SPYNAL CORD TRAUMA. E Mazzon, T. Genovese, C Crisafulli, R Di Paola, C Muià, E Esposito, P Bramanti, J Zhang, Z Wang, S Cuzzocrea.Twelfth Congress Of The European Shok Society, Ulm, Germany, September 14-16 2006.

235) ABSENCE OF PEROXISOME PROLIFERATORS ACTIVATED RECEPTORS ALPHA (PPAR-) ENHANCED THE MULTIPLE ORGAN FAILURE INDUCED BY ZYMOSAN E Esposito, R Di Paola, E Mazzon, T. Genovese, C Muià, C Crisafulli, E Sessa, R Meli, S Cuzzocrea.Twelfth Congress Of The European Shok Society, Ulm, Germany, September 14-16 2006.

236) PROTECTIVE EFFECT OF HYPERICUM PERFORATUM IN ZYMOSAN-INDUCED MULTIPLE ORGAN DYSFUNCTION SYNDROME.E Esposito, R Di Paola, E Mazzon, C Muià, C Crisafulli, T. Genovese, P Di Bella, M Menegazzi, R Meli, S Cuzzocrea.Twelfth Congress Of The European Shok Society, Ulm, Germany, September 14-16 2006.

237) NEUROPROTECTION AND ENHANCED RECOVERY WITH HYPERICUM PERFORATUM EXTRACT AFTER EXPERIMENTAL SPINAL CORD INJURY IN MICE.T. Genovese, E Mazzon, M Menegazzi, R Di Paola, C Muià, C Crisafulli, P Bramanti, H Suzuki, S Cuzzocrea.

FITOMED 2006 II° CONGRESSO INTERSOCIETÀ SULLE PIANTE MEDICINALI. TAORMINA- MESSINA, 6-8 LUGLIO 2006

238) PROTECTIVE EFFECT OF HYPERICUM PERFORATUM IN ZYMOSAN-INDUCED NON SEPTICK SHOCK. E Esposito, R Di Paola, E Mazzon, C Muià, C Crisafulli, T. Genovese, P Di Bella, M Menegazzi, R Meli, H Suzuki, S Cuzzocrea. FITOMED 2006 II° CONGRESSO INTERSOCIETÀ SULLE PIANTE MEDICINALI. TAORMINA- MESSINA, 6-8 LUGLIO 2006

239) ANTHOCYANINS, GREEN TEA AND HYPERICUM PERFORATUM EXTRACTS IN ACUTE INFLAMMATION S Cuzzocrea. FITOMED 2006 II° CONGRESSO INTERSOCIETÀ SULLE PIANTE MEDICINALI. TAORMINA- MESSINA, 6-8 LUGLIO 2006

240) GREEN TEA POLYPHENOL EXTRACT ATTENUATES ISCHAEMIA/REPERFUSION INJURY OF THE GUT. C. Muià, E. Mazzon, R. Di Paola, T. Genovese, M. Menegazzi, A.P. Caputi, H. Suzuki, S. CuzzocreaFITOMED 2006 II° CONGRESSO INTERSOCIETÀ SULLE PIANTE MEDICINALI. TAORMINA- MESSINA, 6-8 LUGLIO 2006

241) GREEN TEA POLYPHENOL EXTRACT ATTENUATES LUNG INJURY IN EXPERIMENTAL MODEL OF CARRAGEENAN-INDUCED PLEURISY IN MICE.C Crisafulli, C. Muià, E. Mazzon, R. Di Paola, T. Genovese, M. Menegazzi, H. Suzuki, S. CuzzocreaFITOMED 2006 II° CONGRESSO INTERSOCIETÀ SULLE PIANTE MEDICINALI. TAORMINA- MESSINA, 6-8 LUGLIO 2006

242) GREEN TEA POLYPHENOL EXTRACT ATTENUATES ZYMOSAN-INDUCED NON SEPTICK SHOCK. IN MICE.R. Di Paola, E. Mazzon, C. Muià, C Crisafulli, T. Genovese, M. P Di Bella, E Esposito, M Menegazzi, R Meli, H Suzuki, S Cuzzocrea. Fitomed 2006 II° congresso intersocietà sulle piante medicinali. Taormina- Messina, 6-8 luglio 2006

243) MELATONIN INHIBITS EXPRESSION OF THE INDUCIBLE ISOFORM OF NITRIC OXIDE SYNTHASE AND CYCLOOXYGENASE-2 IN GLIOMA CELLS. E Esposito, C Muià, G. Mattace Raso, R Meli, S Cuzzocrea. XIII Convegno Monotematico SIF, XI Convegno Nazionale Aspetti Biologici dell’Ossido di Azoto, Urbino –Campus Scientifico Sogesta 19 Settembre 2006.

244) MODULATION OF NITRIC OXIDE HOMEOSTASIS IN MICE MODEL OF SPINAL CORD INJURY. T. Genovese, E. Mazzon, S. Mariotto, M Menegazzi, , H Suzuki, S Cuzzocrea.

XIII Convegno Monotematico SIF, XI Convegno Nazionale Aspetti Biologici dell’Ossido di Azoto, Urbino –Campus Scientifico Sogesta 19 Settembre 2006.

245) INHIBITION OR KNOCK OUT OF INDUCIBLE NITRIC OXIDE SYNTHASE RESULT IN RESISTANCE TO BLEOMYCIN-INDUCED LUNG INJURY. T. Genovese, E. Mazzon, R. Di Paola, MA Sortino, C Cancheri and S Cuzzocrea. XIII Convegno Monotematico SIF, XI Convegno Nazionale Aspetti Biologici dell’Ossido di Azoto, Urbino –Campus Scientifico Sogesta 19 Settembre 2006.

246) ROLE OF PARP-1 AND PARG ENZYMES IN SECONDARY DAMAGE ASSOCIATED WITH MEDULLAR TRAUMA.S. Cuzzocrea XIX Convegno Nazionale “I Processi di ADP- Ribosilazione” Università di Napoli “Federico II” 9-11 Novembre 2006.

247) SOLUBLE GITR (GLUCOCORTICOID- INDUCED TNFR- RELATED GENE) FUSION PROTEIN INHIBITS ACUTE LUNG INFLAMMATION. S. Cuzzocrea, G Nocentini, R. Di Paola, M Agostani, E Mazzon, S Ronchetti, C Crisafulli, A.P. Caputi C. Riccardi 5th International Congress on Autoimmunity Sorrento, Italy Novembre 29-December 3, 2006.

248) ABSENCE OF GITR (GLUCOCORTICOID- INDUCED TNFR- RELATED GENE) REDUCES THE EVOLUTION OF MURINE TYPE ii COLLAGEN- INDUCED ARTHRITIS. S. Cuzzocrea, E Ayroldi, R. Di Paola, M Agostini, E Mazzon, S Bruscoli, T. Genovese, S Ronchetti, A.P. Caputi C. Riccardi 5th International Congress on Autoimmunity Sorrento, Italy Novembre 29-December 3, 2006.

249) EFFECT OF 17-B ESTRADIOL ON SIGNAL TRASDUCTION PATHWAYS AND SECONDARY DAMAGE IN EXPERIMENTAL SPINAL CORD INJURY.S. Cuzzocrea, T. Genovese, E Mazzon, E Esposito, R. Di Paola, C Muià.7th World Congress on Trauma, Shock, Inflammation and Sepsis (TSIS 2007)- Interdisciplinary Summit on Inflammation March 13th-17th 2007 Munich Germany

250) SPLANCHNIC ISCHEMIA REPERFUSION INJURY IS REDUCED BY GENETIC OR PHARMACOLOGICAL INHIBITION OF TNF-A S. Cuzzocrea, E Esposito, E Mazzon, C Muià. R Meli.7th World Congress on Trauma, Shock, Inflammation and Sepsis (TSIS 2007)- Interdisciplinary Summit on Inflammation March 13th-17th 2007 Munich Germany

251) GLYCOGEN SYNTHASE KINASE-3B INHIBITION ATTENUATES THE DEVELOPMENT OF ISCHEMIA/REPERFUSION INJURY OF THE GUT S. Cuzzocrea, E Esposito, E Mazzon, C Muià. M, Abdelrahnam, R. Di Paola,7th World Congress on Trauma, Shock, Inflammation and Sepsis (TSIS 2007)- Interdisciplinary Summit on Inflammation March 13th-17th 2007 Munich Germany

252) ETANERCEPT ATTENUATES THE DEVELOPMENT OF CERULEIN-INDUCED ACUTE PANCREATITIS IN MICE. A COMPARISON WITH TNF-A GENETIC DELETION.S. Cuzzocrea, G, Malleo, E Mazzon, T. Genovese, R. Di Paola, C Muià7th World Congress on Trauma, Shock, Inflammation and Sepsis (TSIS 2007)- Interdisciplinary Summit on Inflammation March 13th-17th 2007 Munich Germany

253) HYDROGEN SULFIDE IN DISEASE.A. Sivaraijah, M Collino, M Yasin, S. Cuzzocrea, C. Thiemermann.7th World Congress on Trauma, Shock, Inflammation and Sepsis (TSIS 2007)- Interdisciplinary Summit on Inflammation March 13th-17th 2007 Munich Germany