U.O Dermatologia UniversitariaDirettore Prof. Paolo Barachini

Linee di ricerca e collaborazioni• Riparazione tessutale cutanea CNR Massa

• Micro-nano biosistemi/sensori Dip. Di Chimica UNIPI

• Analisi 3D-colorimetrica lesioni cutanee ARANZ New Zealand

• Polimorfismi genici in psoriasi-ulcere cutanee UNIPI

• Indicatori prognostici immunoistochimici Dept. Of Dermatology, Univ. Of Miami

• Sviluppo matrici extracellulari dermiche Università di Montpellier

• Psoriasia e ecografia alta risoluzione Reumatologia UNIPI

• Lesioni da pressione Rischio Clinico AOUP

• Acne e ruolo mediatori infiammatori Endocrinologia UNIPI

Smart Wearable and Autonomous Negative pressure device and homecare solution

Swan iCare project

• Exodus coordinator agency Grece

• Commisariat energie atomiques et alternatives France

• Centre Suisse electronique et microtechnique Suisse

• University of Pisa Dept. Of Chemistry Italy

• CHU Diabetic foot Grenoble France

• Euroresearch Italy

• Heamopharm Biofluids Italy

• European wound management association Denmark

• ICCS Univerisy of Athens Grece

• Smith and Nephew United Kingdom

• University of Pisa Dermatology Unit Italy

Biosensori

LED control

Photodiode ADC Spectrographic analysis

Cardiac related pulsatility analysis

Optical probe Mixed-Signal Electronics Signal Processing

Tissueperfusion

TissueOxygenation

&SpO2

Phot

odio

de

LED

(IR

)

LED

(R&

IR)

Negative Pressure Wound Therapy

Healthcare NetworkHospital Infrastructure,

Doctors, Care Center, etc ...

Wire

less

Wid

e Ar

ea N

etw

ork

(GSM

, GPR

S, U

MTS

)

Wire

less

Wid

e Ar

ea N

etw

ork

(GSM

, GPR

S, U

MTS

)

Wireless Local Area Network

(WIFI)

Wireless Local Area Network

(WIFI)

Smartphone (User interface / Gateway)

- GUI application - Remote control and monitoring of the SNPD - Gateway Bluetooth 4.0 or ANT+ Bluetooth WiFi EDGE ; GSM/GPRS ; UMTS

Stationary and ambulatory sensors

- Pulse Oximetry opto-electronic sensors - Insole pressure sensor - Dorsiflexion sensor

Smart Negative Pressure Device

- Wound extracted parameters - Local-in skin and wound temperature - MMPs (1, 2, 3, 8, 9) - TNFa - CRP - pH - Bacteria quantification and identification - Actuator control - Pump - Wearable sensor extracted parameters - SpO2, Heart Rate (HR), Perfusion Index (PI) - Insole pressure on three points - Dorsiflexion parameters - Inside parameters extraction - Activity classification - Embedded electronics - Analog front-end sensor interface - Low Power microcontroller - Power management - Microcontroller - Ultra low power communication module - USB - SD Memory Card - User interface

Smart Disposable interface parts

- Wound surface - Trans Epiderma Water Loss - Release of collagen - Release of growth factors - Release of MMP inhibitors - Biosensing optical fiber - Colometric sensors - Flat wound drain - Tranparent occlusive dressing - Negative pressure capability - Physical sensors - Temperature sensor - Conductivity sensor

Glucose meter

- Measuring range: 20 ~ 630 mg/dL - Data transfer/ communication: ANTwireless

Ear Thermometer

- Measuring Core Body Temperature