CURRICULUM VITAE Zhongjun Jon Wu, Ph.D. Professor of...

CURRICULUM VITAE

Zhongjun Jon Wu, Ph.D.

Professor of Cardiothoracic Surgery

University of Louisville School of Medicine

Date: December 8, 2014

Contact Information

Business Address

Department of Cardiovascular and Thoracic Surgery

Cardiovascular Innovation Institute, room 410

University of Louisville

302 E. Muhammad Ali Blvd

Louisville KY 40202

Phone Number (502) 852 1351

Fax Number (502) 852-5458

E-mail [email protected]

Foreign Languages Chinese

Education

1986 B.S.E. Optical Instruments, Tsinghua University, Beijing, PR China

1989 M.S.E. Optical Engineering, Shanghai Institute of Optics & Fine Mechanics

Chinese Academy of Sciences, PR China

1996 Ph.D. Biomedical Engineering, University of Miami, Coral Gables, FL

Employment History

Academic Appointments:

1996 Research Associate

Department of Biomedical Engineering, University of Miami

1998-2000 Visiting Research Assistant Professor

Department of Surgery, School of Medicine, University of Pittsburgh

2000-2003 Research Assistant Professor

Department of Surgery, School of Medicine, University of Pittsburgh

2003-2009 Assistant Professor

Department of Surgery, University of Maryland School of Medicine

2009- 2011 Associate Professor


2011- 2014 Associate Professor with Tenure


2004-11/2014 Adjunct Faculty Member,

Department of Bioengineering, University of Maryland, College Park, MD

mailto:[email protected]


2014- 11/2014 Professor with Tenure


11/2014- present Professor with Tenure

Department of Cardiovascular and Thoracic Surgery, University of

Louisville School of Medicine

11/2014- present Associate Faculty

Department of Bioengineering, University of Louisville Speed School of

Engineering

Other Employment

1986-1989 Graduate Student Researcher

Shanghai Institute of Optics and Fine Mechanics, Chinese Academy of

Sciences Shanghai, P. R. China

1989-1992 Research Engineer

Shanghai Institute of Optics and Fine Mechanics, Chinese Academy of

Sciences Shanghai, P. R. China

1992-1996 Graduate Student Researcher

Department of Biomedical Engineering, University of Miami, Coral

Gables, FL

1996-1998 Laboratory Project Coordinator/Research Staff

Department of Surgery, UPMC Health System, Pittsburgh, PA

Research Interests and Expertise

Development of Artificial Organs: Ventricular Assist Devices, Blood Pumps, Artificial

Lungs, Respiratory Assist Devices

Computational Modeling and Design Optimization of Blood Contacting Medical Devices

Blood Flow, Flow Visualization, Blood Damage, Cell Mechanics, Cardiac Biomechanics,

Hemodynamics

Biological Responses to Artificial Organs in Human and Animals

Animal Models of Cardiovascular Disease and Development of New Treatment

Technologies

Professional Society Membership

1994-Present Member, American Society for Artificial Internal Organs (ASAIO)

1999-Present Member, Biomedical Engineering Society (BMES)

2002-Present Member, American Society of Mechanical Engineers (ASME)

Honors And Awards 1991 Scientific and Technological Progress Award, Chinese Academy of Sciences 1994 Travel Fellowship Award, American Society for Artificial Internal Organs 1996 Award of Academic Merit, University of Miami

Administrative and Professional Services


Institutional Services

2003-11/2014 Director, Artificial Organs Laboratory

*Oversee staff of 16 and budget of ~ $2.0 million/year

2009-2010 Alternative Member, School of Medicine Council

11/2014 – present Director of Research, Department of Cardiovascular and Thoracic Surgery,

University of Louisville School of Medicine

Local and National Services

Reviewer for Professional Journals

1999-2014 Regular Reviewer ASAIO Journal (>4/year)

2003-2014 Regular Reviewer Artificial Organs (>3/year)

2003 Acta Biotheoretica

2003 ASME Journal of Fluids Engineering

2005-present Annals of Biomedical Engineering

2006, 2011, 2012 Biomechanics and Modeling in Mechanobiology

2006, 2010 Journal of Biomechanics

2008, 2010, 2012 Journal of Membrane Science

2008, 2010 ASME Journal of Biomechanical Engineering

2008 Applied Physics Letters

2010 Applied Mathematical Modeling

2010-2013 The Open Biomedical Engineering Journal (>1/year)

2010-present Cardiovascular Engineering and Technology (>2/year)

2010-present Journal of Engineering in Medicine (>2/year)

2010 The Open Cardiovascular and Thoracic Surgery Journal

2010 Medical Engineering & Physics (>2/year)

2012 Computers in Biology and Medicine

2011 Biochemical Engineering Journal

2011 Journal of Addiction Research & Therapy

2012 Journal of Biomedical Materials Research: Part A

2012 Stem Cells Translational Medicine

2012 Journal of Healthcare Engineering

2012 Computers in Biology and Medicine

2013 BioMedical Engineering OnLine

2013 Circulation (3)

2013 Journal of Fluids and Structures

2013 Applied Mathematics and Mechanics

2014 Journal of Surgical Research (1)

2014 Mathematical Problems in Engineering (1)

2014 Computers in Biology and Medicine (1)

Reviewer for Books and Book Proposals

1999 University of Pittsburgh patent disclosure

2005 Reviewer, Wiley Encyclopedia of Biomedical Engineering


2010 Reviewer, Springer Book Proposal

Reviewer for Grants and Research Proposals

2000 Grant Reviewer for USDA Small Business Innovative Research Program

2003 Grant Reviewer for Kentucky Science and Engineering Foundation 2005 Grant Reviewer for Kentucky Science and Engineering Foundation

2006 Grant Reviewer for John Sealy Memorial Endowment Fund for Biomedical Research

2010 Grant Reviewer for Italian Ministry of Health, General Directorate for Health and

Technologies Research,

2013 Grant Reviewer for Italian Ministry of Health, General Directorate for Health and

Technologies Research,

2009 Member of US FDA Technical Review Committee – FY2010 Science Prioritization

Process, Office of Science and Engineering Laboratories, Center for Devices and

Radiological Health, US Food and Drug Administration (FDA) (2009)

2010~2013 Member of NIH Special Emphasis Panel/Scientific Review Study Section

(SBIR/STTR) – Small Business: Cardiovascular and Surgical Devices: ZRG1 SBTS-E

(10) B (Oct. 2010), ZRG1-SBIBV 12 (Feb, 2012), ZRG1-SBIBV12 (June 2012),

ZRG1-SBIB-V12 (March 2013), ZRG1-SBIB-Y12 (June 2013), ZRG1-SBIB-Y12

(Nov.2013)

Reviewer and Organizer for Professional Conferences

2007, 2008, 2013 Reviewer for the ASAIO Annual Conferences

2009 Reviewer for BMES Annual Meeting

2002 Session Chair, International Congress on Biological and Medical Engineering,

Singapore, December, 2002

2007 Session Chair, 53rd ASAIO Annual Conference, - Chicago, IL

2007 Session Chair, 2nd International Joint Congress of the International Federation for

Artificial

2007 Organs (IFAO) and Japanese Society for Artificial Organs (JSAO). Osaka, Japan

October, 2007.

2009 Session Chair, BMES 2009 Annual Conference, October 7 to 10, 2009, Pittsburgh, PA

2010 Associate Chair – Cardiopulmonary Track, ASAIO 2010 Annual Meeting, Baltimore,

MD

2011 Chair – Cardiopulmonary Track, ASAIO 2011 Annual Meeting, Washington DC

2010 Member of Program Committee of ASAIO Annual Meeting



2014 Chair – Bioengineering Track, ASAIO 2014 Annual Meeting, Washington DC

Editorial Board

2006-present Member of Editorial Board of ASAIO Journal

2008-present Member of Editorial Board of Open Biomedical Engineering Journal

2013-present Member of Editorial Board of Chronicles of Surgery

2012 Guest Editor, International Journal of Biomaterials – Special Issue on Advanced

Surface Modifications for Blood-Contacting Surfaces of Medical Devices


External Assessor for Promotion and Tenure

2010 Texas Tech University

2010 University of Michigan

2011 University of Connecticut

2011 University of Louisville

Other Services

2010 Judge, Ph.D. student paper competition at the ASME Summer Bioengineering

Conference

2013 Howard University's Research Day Judging Committee

2011 - 2012 Member of Board of Trustees of the American Society for Artificial Internal

Organs (ASAIO)

Teaching Responsibilities

Student Mentorship and Supervision

University of Pittsburgh:

1998 Alison Curtis, MS, (Senior Engineer, Edwards LifeScience)

1999 Benjamin Ewing, BS, (Engineer Cook Vascular Inc.)

2001 Rebecca K Gottlieb, Ph.D. (Medtronic MiniMed), Research Advisor and PhD Thesis

Committee

2003 Jeffrey Connors, BS, (Material Sciences and Engineering)

2004 Tim Bachman, BS, (MS, University of Pittsburgh, Bioengineering)

2005 Rui Zhao, MS (PhD Student, Carnegie Mellon University)

University of Maryland, Baltimore:

2004 Thesis committee of Rui Zhao’s Master’s Degree (University of Pittsburgh)

2005 Jennifer Lamos (Summer Student, University of Maryland College Park)

2005 Qing Hu (Summer Student, University of Maryland College Park)

2006 Philip Hewes (Summer Student, Biomedical Engineering, University of Michigan)

2006 David Huang (Bioengineering PhD Student Rotation, University of Maryland College

Park)

2007 Julien Azimzadeh (Summer Student, University of Maryland College Park)

2007 Michael J Hickey (Summer Student, VA-MD Regional College of Veterinary Medicine)

2007 Sumair Akhtar (Summer Medical Student, University of Maryland School of Medicine)

2008 Kristina Rotolo (Summer Student, Biomedical Engineering, Duke University)

2008 Charlie Xu (Summer Student, Biomedical Engineering, Duke University)

2008 Adam Pampori (Summer Student, Bioengineering, University of Maryland College

Park)

2008 Ethan Bassett (Summer Medical Student, University of Maryland School of Medicine)

2008 Jeremy Pollock (Summer Medical Student, University of Maryland School of Medicine)

2009 Brian Miller (Summer Medical Student, University of Maryland School of Medicine)

2009 Colin Gause (Summer Medical Student, University of Maryland School of Medicine)

2009 Craig Stauffer (Summer Medical Student, University of Maryland School of Medicine)

2009 Andrea Saltos (Summer Medical Student, University of Maryland School of Medicine)



Park)


Park)

2010 Ofra Rybak (Summer Student, Mechanical Engineering, University of Michigan)

2010 Gregory Bittle (Summer Medical Student, University of Maryland School of Medicine)

2010 Bryan Buckingham (Summer Medical Student, University of Maryland School of

Medicine)

2011 Chetan Pasrija (Summer Medical Student, University of Maryland School of Medicine)

2011 Charles R Cooper (Summer Medical Student, University of Maryland School of

Medicine)

2012- present, Jun Ding (PhD Student of Mechanical Engineering, University of Maryland

Baltimore County)

2011-present, Adam Behren (PhD thesis committee member, University of Maryland College

Park)

Post-Doctoral Fellow Mentorship and Supervision

2004 – 2006 Juntao Zhang, PhD

2005 – 2008 Guangming Cheng, MD, PhD

2007 – 2008 Yang Gao, MD

2007 – 2009 Won-Bae Chang, MD

2005 – 2009 Tao Zhang, PhD

2009 – 2010 Giacomo Bianchi, MD

2007 – 2010 M Ertan Taskin, PhD

2008 – 2011 Katharine H Fraser, PhD

2009 – 2011 Kang Zhou, MD

2009 – 2012 Xufeng Wei, MD, PhD

2010 – 2012 Yunshang Zhao, PhD

2010 – 2012 Pei Zhang, PhD

2010 – 2013 Narayana Garimella, PhD

2012 – 2014 Yang Liu, MD, PhD

2009 – 2014 Pablo Sanchez, MD, PhD

2011 – 2014 Jiafeng Zhang, PhD

2102 – present Nandan K Mondal, PhD

2014 – present Zengshen Chen, PhD

Resident Mentorship and Supervision

2004 – 2005 Deyanira Prastein, MD

2004 – 2006 Ahmet Kilic, MD

2005 – 2007 G Kwame Yankey, MD

2008 – 2009 Marc Gibber, MD

2011 – 2013 A Claire Watkins, MD


Visiting Scholar

2009-2011 Hosting Visiting Associate Professor Ho Sung Son, MD, PhD, Korea

University, College of Medicine. Dept. of Thoracic and Cardiovascular Surgery

Grant Support

Active Grants

07/05/13-03/31/18 (PI: 40%) MPI: BP Griffith/ ZJ Wu

“First-In-Human Use of an Artificial Lung for Ambulatory

Respiratory Support”

NIH/NHLBI 1R01HL118372-01

Total Cost: $4,946,992

Role: PI

06/28/12-06/27/15 (Co-Investigator: 10%) PI: BP Griffith

"Improving MSC Engraftment in the Ischemic Heart"

Maryland Stem Cell Research Fund

Total Cost: $689,958.00

Role: serve as Co-Investigator to manage the daily research

activities for the project

07/24/2013-7/23/2015 (Co-Investigator: 5%) PI: PG Sanchez

“Bone Marrow Derived Stem Cells to Improve Donor Lung

Quality & Transplant Outcomes”


Total Cost: $200,000

Role: Co-Investigator

01/15/2014 - 12/31/2014 (Co-Investigator: 5%) PI: R Jarvik

“Administrative Center for PumpKIN Pre-Clinical Contractors”

HHSN268201200001I (NIH/NHLBI)


Role: Co-Investigator

Pending Grants:

04/1/15-03/31/19 (PI: 20 %) MPI: ZJ Wu/BP Griffith

"Shear-Induced Hemostatic Dysfunction and Bleeding in CF-VAD

recipients"

NIH 1R01 HL124170-01A1

Total Cost: $ 2,119,944 (8 percentile, award is pending)

04/1/15-03/31/19 (PI: 5 %) PI: ZJ Wu (subcontract)

“Paracorporeal VAD for versatile Circulatory Support”

NIH R43HL124830-01A1

Total Cost: $61,400 (Priority Score: 35)


Completed Grants

05/01/95-09/30/00 (Co-Investigator: 50%) PI: BP Griffith

“Development of the University of Pittsburgh Streamliner Blood

Pump”

McGowan Foundation/University of Pittsburgh


10/01/95-09/30/00 (Co-Investigator: 25 %) PI: K Butler (Nimbus, Inc.)

“Development of an Innovative Ventricular Assist System”

NIH/NHLB1 N01-HV-58155

Total Cost: $4,091,336 ($2,661,452 contracted to University of

Pittsburgh)

03/01/97-07/01/97 PI

“Flow Visualization Study of AB-180 Centrifugal Blood Pump”

Cardiac Assist Technologies, Inc.

Total Cost: $18,000

08/01/99-12/31/99 PI

“Hemodynamic Study of Arterial Cannulae”

Cardiac Assist Technologies, Inc

Total Cost: $15,000

08/01/99-03/31/00 PI

“Hemodynamic Study of Blood Filtering Devices”

Metamorphic Surgical Devices, Inc.

Total Cost: $13,300

04/01/00-03/31/05 (Co-Investigator: 20%) PI: Bartley P. Griffith

“Bioengineering – Biological Study of Non-Pulsatile Perfusion”

NIH/NIBIB R01EB02076

Total Direct Cost: $1,281,813


“Development of a Chronic Artificial Lung”

NIH/NHLB1 1R01HL60740


09/01/00-08/31/04 (Co-Investigator:10%) PI: O. Ghattas/JF Antaki

“Simulation of Flows with Dynamic Interfaces on Multi-Teraflop

Computers”

NSF ACI #0086093


07/01/01-08/31/01 PI

“Flow Visualization Study of Medtronic MiniMed Intravascular


Glucose Sensor”

Medtronic MiniMed

Total Cost: $2,700

07/01/01-06/30/02 Sub-Contract PI

“Physiological Controller for Rotary Blood Pumps”

NIH/NHLBI-SBIR R43HL066656

Subcontract with Antakamatics Inc

Total Cost: $98,000


“Development of Artificial Organs and Related Products”

State of Pennsylvania


07/01/01-12/30/02 PI

“Flow Visualization of HeartQuest CF4 Blood Pump”

MedQuest Medical, Inc.

Total Cost: $27,000

10/01/01-03/31/03 (Co-Investigator: 5%) PI: Sarangapani/Antaki

“Fuel Cell Power Packs for Left Ventricular Assist Devices”

NIH/NHLBI 2R44HL61069-02A1

Total Direct Cost: $46,811 (to University of Pittsburgh)

03/01/02-02/28/05 (Co- Investigator: 20%) PI: Michael S. Sacks

“Biomechanical Optimization of TE Heart Valves”

NIH/NHLBI R01HL068816

Total Direct Cost: $750,000

04/01/02-03/31/06 (Co-Investigator/Consultant) PI: William J. Federspiel

“Percutaneous Respiratory Assist Catheter”

NIH/NHLBI R01HL070051


07/01/02-06/30/03 PI

“Flow Visualization of Thoratec HeartMate III Maglev

Centrifugal Blood Pump”

Engineering and Applied Sciences, Inc.

Total Cost: $13,000

07/01/02-06/30/03 (Co-Investigator: 20%) PI: AJ Russell

“Development of Artificial Organs and Related Products”

Commonwealth of Pennsylvania: ME#02-223



07/01/03-06/30/07 Proposal Contributor as Co-Investigator

PI: KB Chandran

“Fluid Structure Simulation for Prosthetic Heart Valves”

NIH/NHLB1 1R01HL071814


02/01/06-01/31/07 STTR Research Institution PI

PI: B Biancucci/ZJ Wu

“Impeller optimization for a combined pump-oxygenator”

NIH R41 HL083621

Total Cost: $200,046 ($100,309 to University of Maryland)

04/01/06-03/31/07 STTR Research Institution PI

PI: K Dasse/ZJ Wu

“Integrated Maglev Pump-Oxygenator for Respiratory Failure”

NIH R41 HL084807

Total Cost: $266,988 ($101,613 to University of Maryland)

04/01/04-03/31/09 (Co-Investigator: 5 to 30 %) PI: Robert Jarvik/Bartley Griffith

“Pediatric Circulatory Support”

NIH/NHLBI HHSN268200448190C


06/01/09-08/31/10 PI (supplement support) PI: ZJ Wu

“Linking Multi-scale Dynamics of Shear-Induced Blood Damage

to CFD Modeling”

NIH/NHLBI 3R01HL088100-02S109

Total Cost: $20,625

08/01/09-05/31/12 PI (supplement support) PI: ZJ Wu


to CFD Modeling”

NIH/NHLBI 3R01HL088100-02S209


04/01/08-03/31/12 (UMB Principle Investigator: 5 %) PI: K Dasse/ZJ Wu

“Integrated Magley Pump-Oxygenator for Respiratory Failure”

NIH/NHLBI R42 HL084807

Total Cost: $1,395,479 ($732,311 to University of Maryland)

04/01/06-03/31/13 (Co-Investigator: 15 %) PI: Bartley P. Griffith

“Strain Controlled LVAD Unloading and Post MI Remodeling”

NIH/NHLBI R01 HL 081106





05/01/09-04/30/13 (Co-Investigator: 5%) PI: Bartley P Griffith

“Engineering Cardiac Stem Cells for Heart Repair”

McGowan Charitable Fund




07/15/09 - 7/31/13 (UMB PI: 5%) PIs: G Farnan/ZJ Wu

“CircuLite's Circulatory Support System in Children and Infants”

NIH/NHLBI 1R44HL096214 (NCE)

Total Cost: $2,943,568.80

01/15/10-01/14/14 (Co-Investigator: 10 %) PI: BP Griffith

“Pumps for Kids, Infants and Neonates (PumpKIN) Pre-Clinical

Program”



Role: serve as Co-Investigator to manage the daily activities for the

project

01/15/10-01/14/14 (Co-Investigator: 10 %) PIs: R Jarvik/BP Griffith

“Pumps for Kids, Infants and Neonates (PumpKIN) Pre-Clinical

Program”





08/1/12-07/31/14 (Co-PI: 2%) PIs: P Kofinas/ZJ Wu

"Synthetic Polymer Functional Hydrogel for Hemorrhage Control"

University of Maryland Baltimore-University of Maryland College

Park Seed Grant

Total Cost: $75,000

07/24/13-7/23/15 (Co-Investigator, 5%) PI: PG Sanchez

"Bone Marrow Derived Stem Cells to Improve Donor Lung

Quality & Transplant Outcomes"



05/1/2013-04/30/15 (PI: 1%) PI: ZJ Wu

"Particle Image Velocimetry (PIV) Study of the Thoratec

HeartMate III Ventricular Assist Device"


Thoratec Corporation

Total Cost: $50,000

05/01/07-04/30/14 (Co-Investigator: 15 %) PI: BP Griffith

“Development of an Artificial Pump-Lung for Respiratory

Failure”

NIH/NHLBI R01 HL082631




09/01/08-05/31/14 (PI: 15 %) PI: ZJ Wu


to CFD Modeling”

NIH/NHLBI R01 HL 088100


Patents

1. Touch down of blood pump impellers. US Patent 6,761,532, July 13, 2004.

2. Method and apparatus for providing limited back-flow in a blood pump during a non-

pumping state. US patent application filed on December 19, 2002. US Patent Application

Publication No.: US 2003/0144574 A1. July 31, 2003.

3. Blood Pump-Oxygenator System. US patent application filed on September 13, 2004. US

Patent Application Publication No.: US 2007/0249888 A1. October 25, 2007.

4. Integrated centrifugal blood pump-oxygenator, an extracorporeal life support system and a

method of a method of de-bubbling and priming an extracorporeal life support system. US

Patent 8,496,874 B2, August 2013.

5. Biocompatible Coating Compositions. US Patent Application PCT/US2014/010391, filed on

January 7, 2014.

6. Self-Expanding Cannula. US Patent Application PCT/US14/46978, file on July 18, 2014.

7. Blood Oxygenator. US Provisional Patent Application, filed on December 22, 2013.

8. Self-Seal Double Lumen Cannula. US Provisional Patent Application filed on November 14,

2014.

9. An Artificial Lung System and Its Methods of Use. US Provisional Patent Application filed

on November 19, 2014.

Publications

Peer-reviewed Journal Articles

1. Yang XY, Wu ZJ and Wu MX. A New Optical Method Used for Measuring the Runout of

Shafting. Measurement Technique, No. 2: 1-3, 1988, (in Chinese).


2. Chen QS and Wu ZJ. A Simple Measurement Method of Repeatability Error of Limit Switch.

Measurement Technique, No. 12: 14-15, 1990 (in Chinese).

3. Wu ZJ, Chen XZ and Sun BD. A Vibrating Stage with Spring-supporting for Testing

Recording Characteristics of Optical Storage Media. Chinese Journal of Lasers, 18:333-336,

1991 (in Chinese).

4. Li XS, Wu ZJ, Gan BH and Sun JF. An Automatic Instrument for Measuring Defects of

Optical Disk Substrates. Chinese Journal of Scientific Instrument. Vol.13: 136-142, 1992 (in

Chinese).

5. Wu ZJ, Li XS, Gan BH and Sun JF. Fast Classification and Counting of Surface Defects and

Evaluation of Surface Performances for Optical Disks. Chinese Journal of Lasers, Vol. A20,

No. 12: 921-925, 1993.

6. Bluestein D, Menon S, Wu ZJ, Haubold A, Armitage TH and Hwang NH. Closing Behavior

of a New Bileaflet Mechanical Heart Valve. ASAIO J 39:398-402, 1993.

7. Wu ZJ, Shu MC, Scott DR and Hwang NH. The Closing behavior of Medtronic Hall

Mechanical Heart Valves. ASAIO J 40: 702-706, 1994.

8. Wu ZJ, Wang Y and Hwang NH. Occluder Closing Behavior: A key Factor in Mechanical

Heart Valve Cavitation. J Heart Valve Dis 3 (Suppl. I): 25-34, 1994.

9. Wu ZJ, Gao BZ and Hwang NH. Transient Pressure at Closing of a Monoleaflet Mechanical

Heart Valve Prosthesis: Mounting Compliance Effect. J Heart Valve Dis 4:553-567, 1995.

10. Wu ZJ and Hwang NH. Ventricular Pressure Slope (dp/dt) and Bileaflet Mechanical Heart

Valve Closure. ASAIO J 41:763-767, 1995.

11. Wu ZJ and Hwang NH. Asynchronous Closure and Leaflet Impact Velocity of Bileaflet

Mechanical Heart Valves. J Heart Valve Dis 4: (Suppl. I): 38-49, 1995.

12. Wu ZJ, Slonin JH and Hwang NH. Transient Pressure Signals in Mechanical Heart Valve

Cavitation. ASAIO J 42: 555-561, 1996.

13. Wu ZJ, Gao BZ, Slonin JH and Hwang NH. Bileaflet Mechanical Heart Valves at Low

Cardiac Outputs. ASAIO J 42: 747-749, 1996.

14. Amin DV, Antaki JF, P Litwak, Thomas D, Wu ZJ, Yu YC, Choi S, Boston JR and Griffith

BP. Controller for an Axial Flow Blood Pump. Biomed Instrum Technol 31:483-487, 1997.

15. Thomas DC, Butler KC, Taylor LP, Le Blanc P, Griffith BP, Kormos RL, Borovetz HS, Wu

ZJ and Antaki JF. Continued Development of the Nimbus/University of Pittsburgh (UOP)

Axial Flow Left Ventricular Assist System. ASAIO J 43:564-566, 1997

16. Amin DV, Antaki JF, Litwak P, Thomas D, Wu ZJ, Watach M. Induction of ventricular

collapse by an axial flow blood pump. ASAIO J 44: M685-690, 1998.

17. Curtis AS, Wu ZJ, Kormos RL and Antaki JF.A Novel Ventricular Apical Cannula: In-Vitro

Evaluation Using Transparent Compliant Casts. ASAIO J 44: 691-695, 1998.

18. Thomas D, Butler KC, Taylor L, LeBlanc P, Griffith B, Kormos R, Borovetz H, Litwak P,

Kameneva M, Choi S, Burgreen G, Wu Z, Antaki J. Year two progress of the Nimbus-

University of Pittsburgh (UoP) axial flow left ventricular assist system. ASAIO J 44: M521-

524, 1998.


19. Wu ZJ, Antaki JF, Burgreen GW, Thomas D, Butler KC and Griffith BP. Fluid Dynamic

Characterization of Operating Conditions for Continuous Flow Blood Pumps. ASAIO J 45:

442-449, 1999.

20. Burgreen GW, Antaki JF, Wu ZJ, LeBlanc P and Butler KC. A Computational and

Experimental Comparison of Two outlet Stators for the Nimbus LVAD. ASAIO J 45:328-

333, 1999.

21. Wu ZJ, Gottlieb RK, Burgreen GW, Holmes JA Borzelleca DC, Kameneva MV Griffith

BP, and Antaki JF. Investigation of Fluid Dynamics within a Miniature Mixed Flow Blood

Pump. Experiments in Fluids 31:615-629, 2001.

22. Burgreen GW, Antaki JF, Wu ZJ, Holmes JA. Computational fluid dynamics as a

development tool for rotary blood pumps. Artificial Organs 25:336-340, 2001.

23. Litwak KN, Kihara S, Kameneva MV, Litwak P, Uryash A, Wu ZJ, Griffith BP. Effects of

continuous flow left ventricular assist device support on skin tissue microcirculation and

aortic hemodynamics. ASAIO Journal 49:103-107, 2003.

24. Kihara S, Litwak KN, Nichols L, Litwak P, Kameneva MV, Wu ZJ, Kormos RL, Griffith

BP. Smooth muscle cell hypertrophy of renal cortex arteries with chronic continuous flow

left ventricular assist. Annals of Thoracic Surgery 75: 178-83, 2003.

25. Hildebrand D, Wu ZJ, Mayer J, Sacks M. Design and Hydrodynamic Evaluation of A Novel

Pulsatile Bioreactor for Biologically Active Heart Valves. Annals of Biomedical Engineering

32(8):1039-1049, 2004.

26. Kameneva MV, Wu ZJ, Urash A, Repko B, Litwak KN, Billiar TR, Fink MP, Simmons RL,

Griffith BP, Borovetz HS. Blood soluble drag-reducing polymers prevent lethality from

hemorrhagic shock in acute animal experiments. Biorheology 41(1):53-64, 2004.

27. Burgreen GW, Loree HW, Bourque K, Dague C, Poirier VL, Farrar D, Hampton E, Wu ZJ,

Gempp TM, Schöb R. Computational Fluid Dynamics Analysis of a Maglev Centrifugal Left

Ventricular Assist Device. Artificial Organs 28: 874-881, 2004.

28. Litwak KN, Koenig SC, Tsukui H, Kihara S, Wu Z, Pantalos GM. Effects of left ventricular

assist device support and outflow graft location upon aortic blood flow. ASAIO J 50:432-7,

2004.

29. Wu ZJ, Gartner M, Litwak KN, Griffith BP. Progress toward an ambulatory artificial lung. J

Thorac Cardiovasc Surg. 2005 Oct; 130(4):973-8.

30. Zhao R, Antaki JF, Naik T, Bachman TN, Kameneva MV, Wu ZJ. Microscopic

Investigation of Erythrocyte Deformation Dynamics. Biorheology 2006, Vol. 43: 747 - 765.

31. Kilic A, Li T, Nolan TDC, Nash JR, Li S, Prastein DJ, Schwartzbauer G, Moainie SL,

Yankey GK, DeFilippi C, Wu ZJ and Griffith BP. Strain-Related Regional Alterations of

Calcium-Handling Proteins in Myocardial Remodeling. J Thorac Cardiovasc Surg,

132(4):900-8, 2006.

32. Zhang J, Gellman B, Koert A, Dasse KA, Gilbert RJ, Griffith BP, Wu ZJ. Computational

and Experimental Evaluation of the CentriMag® Blood Pump. Artificial Organs 30 (3):168-

177, 2006.

33. Gammie JS, Yankey GK, Nolan T, Wu ZJ, Dickfeld T, Cartier C, Tremblay A; MacNeil TP,

Burke A, Griffith BP. Beating Heart Direct Left Atrial Access Balloon Cryoablation: Safety


and Efficacy of Pulmonary Vein Isolation in an Ovine Model. Innovations: Technology &

Techniques in Cardiothoracic & Vascular Surgery. 2(4):188-191, July 2007

34. Kilic A, Nolan TDC, Li T, Yankey GK, Prastein DJ, Jarvik RK, Wu ZJ and Griffith BP.

Early In-Vivo Experience with the Pediatric Jarvik 2000 Heart. ASAIO Journal 53 (3):374-8,

2007 (corresponding author).

35. Zhang J, Koert A, Gellman B, Gempp T, Dasse KA, Gilbert RJ, Griffith BP and Wu ZJ.

Optimization of a Miniature Maglev Ventricular-Assist Device (VAD) for Pediatric

Circulatory Support. ASAIO J. 53(1):23-31, 2007.

36. Zhang J, Nolan TDC, Zhang T, Griffith BP and Wu ZJ. Characterization of membrane blood

oxygenation devices using computational fluid dynamics. Journal of Membrane Science. Vol.

288(1-2): 268-279, 2007

37. Yankey GK, Li T, Kilic A, Cheng G, Satpute A, Savai K, Li S, Moainie SL, Prastein D,

DeFillipi C, Wu ZJ, Griffith BP. Regional Remodeling Strain and Its Association with

Myocardial Apoptosis Post-Myocardial Infarction in Ovine Model. J Thorac Cardiovasc Surg

135(5):991-8, 998.e1-2, 2008.

38. Gottlieb RK, Shu F, Kameneva MV, Antaki JF, Wu ZJ, Burgreen GW. Liquid crystal shear

stress sensor for blood and other opaque viscous fluids. Journal of Flow Visualization and

Image Processing. 16: 51-71, 2009.

39. Zhang T, Cheng G, Koert A, Zhang J, Gellman B, Yankey GK, Satpute A, Dasse KA, Gilbert

RJ, Griffith BP, Wu ZJ. Functional and Biocompatibility Performances of an Integrated

Maglev Pump-Oxygenator. Artificial Organs 33 (1):36-45, 2009.

40. Zhang J, Taskin ME, Koert A, Zhang T, Gellman B, Dasse KA, Gilbert RJ, Griffith BP, Wu

ZJ. Computational Design and In-Vitro Characterization of an Integrated Maglev Pump-

Oxygenator (IMPO). Artificial Organs 2009; 33:805-817.

41. Marhefka JN, Zhao R, Wu ZJ, Velankar SS, Antaki JF and Kameneva MV. Drag reducing

polymers improve tissue perfusion via modification of the RBC traffic in microvessels.

Biorheology 2009; 46:281-292.

42. Pantalos G, et al. Use of computer and in vitro modeling techniques during the development

of pediatric circulatory support devices: National Heart, Lung, and Blood Institute Pediatric

Assist Device Contractor's Meeting: Pediatric Modeling Techniques Working Group. ASAIO

J. 2009; 55:3-5. Erratum in: ASAIO J. 2009;55:307.

43. Fraser KH, Zhang T, ME Taskin, Griffith BP, Wu ZJ. Computational Fluid Dynamics

Analysis of Thrombosis Potential in Left Ventricular Assist Device Drainage Cannulae.

ASAIO Journal 56:157-163, 2010.

44. Gibber M, Wu ZJ, Chang WB, Bianchi G, Hu J, Garcia J, Jarvik R, Griffith BP. In-Vivo

Experience of the Child Size Pediatric Jarvik 2000 Heart: Update. ASAIO J. 2010 Jul-

Aug;56(4):369-76. PMID: 20467298 (corresponding author).

45. Taskin ME, Zhang T, Gellman B, Fleischli A, Dasse KA, Griffith BP, Wu ZJ.

Computational Characterization of Flow and Hemolytic Performance of the UltraMag TM

Blood Pump for Circulatory Support. Artificial Organs 2010 Dec;34(12):1099-113.. PMID:

20626739.


46. Taskin ME, Fraser KH, Zhang T, Griffith BP, Wu ZJ. Micro-scale Modeling of Flow and

Oxygen Transfer in Hollow Fiber Membrane Bundle. Journal of Membrane Science 2010;

362: 172-183. PMID: 20802783.

47. Casey BJ, Behrens AM, Hess JR, Wu ZJ, Griffith BP, Kofinas P. FVII Dependent

Coagulation Activation in Citrated Plasma by Polymer Hydrogels. Biomacromolecules. 2010

Dec 13;11(12):3248-55. PMID: 21058718.

48. Fraser KH, Taskin ME, Griffith BP, Wu ZJ. The use of Computational Fluid Dynamics in

the Development of Mechanical Circulatory Support Devices. Med Eng Phys. 2011

Apr;33(3):263-80. PMID: 21075669.

49. Zhang T, Taskin ET, Fang HB, Pampori A, Jarvik R, Griffith BP, Wu ZJ. Study of Flow-

induced Hemolysis using Novel Couette-Type Blood-Shearing Devices. Artificial Organs

2011 Dec;35(12):1180-6.

50. Garcia JP, Kon ZN, MD, Evans C, Wu Z, Iacono AT, McCormick B and Griffith BP.

Ambulatory veno-venous extracorporeal membrane oxygenation: Innovation and pitfalls. J

Thorac Cardiovasc Surg. 2011 Oct;142(4):755-61. PMID: 21924145

51. Wu ZJ, Gellman B, Zhang T, Taskin ME, Dasse KA, Griffith BP. Computational Fluid

Dynamics and Experimental Characterization of the Pediatric Pump-Lung. Cardiovasc Eng

Tech 2011; 2:276-287.

52. Zhang T, Wei X, Bianchi G, Griffith BP and Wu ZJ. A novel wearable pump-lung device:

in-vitro and acute in-vivo study. Journal of Heart and Lung Transplantation, 2012

Jan;31(1):101-5. Epub 2011 Oct 20. PMID: 22014451 (Featured on cover page).

53. Wu ZJ, Zhang T, Bianchi G, Wei X, Son H-S, Zhou K, Taskin ME, Wang P, Bianccuci B,

Garcia J, Griffith BP. 30-Day In-vivo Performance of a Wearable Artificial Pump-Lung for

Ambulatory Respiratory Support. Ann Thorac Surg. 2012 Jan;93(1):274-81.

54. Wu ZJ, Taskin ME, Zhang T, Griffith BP. Computational Model-Based Design of a

Paracorporeal Artificial Pump-Lung for Cardiopulmonary/Respiratory Support. Artif Organs.

2012 Apr;36(4):387-99. doi: 10.1111/j.1525-1594.2011.01369.x. [Epub ahead of print]

PMID: 22145732.

55. Taskin ME, Fraser KH, Zhang T, Wu CF, Griffith BP, Wu ZJ. Evaluation of Eulerian and

Lagrangian Models for Hemolysis Estimation. ASAIO J. 2012 Jul;58(4):363-72. PMID:

22635012

56. Taskin ME, Zhang T, Fraser KH, Griffith BP, Wu ZJ. Design Optimization of a Wearable

Artificial Pump-Lung Device with Computational Modeling. ASME Journal of Medical

Devices 2012, Vol. 6 / 031009-1. [DOI: 10.1115/1.4007282]

57. Fraser KH, Zhang T, Taskin ME, Griffith BP, Wu ZJ. A Quantitative Comparison of

Mechanical Blood Damage Related Parameters in Rotary Ventricular Assist Devices. ASME

Journal of Biomechanical Engineering 2012, Vol. 134 / 081002-1. [DOI:10.1115/1.4007092]

58. Wu ZJ, Garimella N, Larsson R, Brynda E. Advanced Surface Modifications for Blood-

Contacting Surfaces of Medical Devices. Int J Biomater. 2012; 2012:291735. doi:

10.1155/2012/291735. Epub 2012 Jul 5.PMID: 22829827.

59. Zhao Y, Li T, Wei X, Bianchi G, Hu J, Sanchez PG, Xu K, Zhang P, Pittenger MF, Wu ZJ,

Griffith BP. Mesenchymal Stem Cell Transplantation Improves Regional Cardiac Remodeling

http://www.ncbi.nlm.nih.gov/pubmed/21058718

http://www.ncbi.nlm.nih.gov/pubmed/21058718


Following Ovine Infarction. Stem Cells Translational Medicine 2012;1:685– 695 (co-

corresponding author, featured paper with press release).

60. Sanchez PG, Bittle GJ, Williams K, Pasrija C, Xu K, Wei X, Garcia JP, Wu ZJ, Griffith BP.

Ex-Vivo Lung Evaluation Of Pre-Arrest Heparinization in Donation After Cardiac Death.

Annals of Surgery 2013 Mar;257(3):534-41. doi: 10.1097/SLA.0b013e318273bef1.PMID:

23108122.

61. Wei X, Li T, Son HS; Li S, Wu ZJ, Griffith BP. Chronic Animal models for evaluation of

implantable pediatric ventricular assist devices. ASAIO J. 2013 Jan-Feb;59(1):75-80. doi:

10.1097/MAT.0b013e31827986fe. Erratum in: ASAIO J. 2013 Mar-Apr;59(2):193. Sanchez,

Pablo [corrected to Sanchez, Pablo G]. PMID:23254234 (corresponding author)

62. Wei X, Li T, Li S, Son HS, Sanchez PG, Niu S, Watkins AC, DeFilippi C, Jarvik R, Wu ZJ,

Griffith BP. Acute hemodynamic evaluation of the infant Jarvik ventricular assist device in a

piglet animal model. Journal of Heart and Lung Transplantation 2013 Jan;32(1):112-9. doi:

10.1016/j.healun.2012.10.011.PMID: 23260711(Corresponding author) (Featured on cover

page).

63. Zhang J, Zhang P, Fraser KH, Griffith BP, Wu ZJ. Comparison of fluid dynamic numerical

models for a clinical ventricular assist device and experimental validation. Artificial Organs

2013 Apr;37 (4):380-9. doi: 10.1111/j.1525-1594.2012.01576.x. Epub 2013 Feb 27.PMID:

23441681.

64. Zhou K, Niu S, Bianchi G, Wei X, Garimella N, Griffith BP, Wu ZJ. Biocompatibility

Assessment of a Long-Term Wearable Artificial Pump-Lung in Sheep. Artif Organs. 2013

Aug;37(8):678-88. doi: 10.1111/aor.12049. Epub 2013 Mar 3.PMID: 23452221.

65. Wei X, Li T, Hagen B, Zhang P, Sanchez P, Williams K, Li S, Bianchi G, Son HS, Wu C,

DeFilippi C, Xu KY, Lederer WJ, Wu ZJ, Griffith BP. Short-term Mechanical Unloading

with Left Ventricular Assist Devices after Acute Myocardial Infarction Conserves Calcium

Cycling and Improves Heart Function. JACC: Cardiovascular Interventions 2013

Apr;6(4):406-15. doi: 10.1016/j.jcin.2012.12.122. Epub 2013 Mar 20.PMID: 23523452 (co-

corresponding author).

66. Li T, Kilic A, Wei X, Wu C, Schwartzbauer G, Yankey K, DeFilippi C, Bond M, Wu ZJ,

Griffith BP. Regional imbalanced activation of the calcineurin/BAD apoptotic pathway and

the PI3K/Akt survival pathway after myocardial infarction. Int J Cardiol. 2013 Jun

5;166(1):158-65. doi: 10.1016/j.ijcard.2011.10.107. Epub 2011 Nov 15. [Epub ahead of print]

PMID: 22088220 (co-corresponding author).

67. Li T, Wei X, Sanchez PG, AC Watkins, Wu ZJ, Griffith BP. Prophylactic amiodarone and

lidocaine improve survival in an ovine model of large size myocardial infarction. J Surg Res.

2013 Nov;185(1):152-8. doi: 10.1016/j.jss.2013.05.050. Epub 2013 Jun 7. PMID:23773712

(co-corresponding author).

68. Mondal NK, Sorensen E, Hiivala N, Feller E, Griffith BP, and Wu ZJ. Oxidative Stress,

DNA Damage and Repair in Heart Failure Patients after Implantation of Continuous Flow

Left Ventricular Assist Devices. Int J Med Sci. 2013 May 20;10(7):883-93. doi:

10.7150/ijms.6219. Print 2013. PMID: 23781134.

69. Casey BJ, Behrens AM, Tsinas ZI, Hess JR, Wu ZJ, Griffith BP, Kofinas P. In vitro and in

vivo evaluation of polymer hydrogels for hemorrhage control. J Biomater Sci Polym Ed


2013;24(15):1781-93. doi: 10.1080/09205063.2013.801707. Epub 2013 Jun 6.

70. Gao Y, Li T, Wu C, Bittle G, Chen S, Wu ZJ, Griffith BP. Pim-1 Mediated Signaling during

the Process of Cardiac Remodeling Following Myocardial Infarction in Ovine Hearts. J Mol

Cell Cardiol. 2013 Oct;63:89-97. doi: 10.1016/j.yjmcc.2013.07.012. Epub 2013 Jul 27.

PMID: 23899906 (co-corresponding author).

71. Zhang JF, Chen X, Fraser KH, Taskin ET, Griffith BP, Wu ZJ. Computational Study of the

Blood Flow in Three Types of 3D Hollow-Fiber Membrane Bundles. J Biomech Eng. 2013

Dec;135(12):121009. doi: 10.1115/1.4025717. PMID: 24141394

72. Hu J, Mondal NK, Sorensen E, Cai L, Fang HB, Griffith BP, Wu ZJ. Platelet glycoprotein

Ibα (GPIbα) ectodomain shedding and non-surgical bleeding in heart failure patients

supported by continuous flow left ventricular assist devices (CF-LVADs). J Heart Lung

Transplant. 2014 Jan;33(1):71-9. doi: 10.1016/j.healun.2013.08.013. Epub 2013 Sep

19.PMID: 24055626

73. Behrens AM, Sikorski MJ, Li T, Wu ZJ, Griffith BP, Kofinas P. Blood Aggregating

Hydrogel Particles for Use as a Hemostatic Agent. Acta Biomater. 2014 Feb;10(2):701-8.

PMID: 24185001

74. Liu Y, Sanchez PG, Wei X, Li T, Watkins AC, Li SY, Griffith BP, Wu ZJ. Right ventricular

unloading and respiratory support with a wearable artificial pump-lung (APL) in an ovine

model. J Heart Lung Transplant. 2014 Feb 26. pii: S1053-2498(14)01004-3. doi:

10.1016/j.healun.2014.02.026. [Epub ahead of print]. PMID:24746636

75. Mondal NK, Sorensen EN, Hiivala NH, Feller ED, Pham SM, Griffith BP, Wu ZJ.

Intraplatelet reactive oxygen species, mitochondrial damage and platelet apoptosis augment

non-surgical bleeding in heart failure patients supported by continuous-flow left ventricular

assist device. Platelets. 2014 Aug 28:1-9. [Epub ahead of print] PMID: 25167344

76. Zhao Y, Hu J, Buckingham B, Pittenger M, Wu ZJ, Griffith BP. Pim-1 kinase cooperates

with serum signal supporting MSC propagation. Cells Tissues Organs. 2014 Nov 11. [Epub

ahead of print]. PMID:25402318 (corresponding author).

77. Ding J, Chen Z, NiuS, Zhang J, Mondal NK, Griffith BP and Wu ZJ. Quantification of

Shear-Induced Platelet Activation: High Shear Stresses for Short Exposure Time. Artif

Organs (in press).

78. Wei X, Sanchez PG, Liu Y, Li T, Watkins AC, Wu ZJ, Griffith BP. Mechanical Circulatory

Support of a Univentricular Fontan Circulation with a Continuous Axial-Flow Pump in a

Piglet Model. ASAIO J. 2014 Nov 13. [Epub ahead of print] PMID: 25396272

(corresponding author).

79. Ding J, Niu S, Chen Z, Zhang T, Griffith BP, Wu ZJ. Shear-Induced Hemolysis: Species

Differences. Artif Organs (in press).

80. Liu Y, Sanchez PG, Wei X, Watkins AC, Niu S, Wu ZJ, Griffith BP. Thirty-Day

Cardiopulmonary Support with a Novel Pediatric Pump-Lung (PediPL) in an Ovine Animal

Model. Artif Organs (accepted, minor revision) (corresponding author).

Book Chapters:


1. Wu ZJ, JF Antaki, K Litwak, MV Kameneva, HS Borovetz, RL Kormos. Ventricular assist

devices: current status and future perspective. In New Frontiers in Biomedical Engineering.

Hwang (ed), Kluwer Academic Publisher, New York, 2003.

Peer Reviewed Conference Papers

1. Yan HB, Gan FX and Wu ZJ. Structural Change Characteristics of the Vapor-deposited

Al-Cu Alloy Films. SPIE, Vol. 1230: 699-700, 1990.

2. Wu ZJ, Pan T, Chen XZ, Sun BD and Yuan HJ. Investigation of the Microscopical

Readout Characteristics of Optical Recording Media. SPIE, Vol. 1230: 675-677, 1990.

3. Curtis AS, Meyer RK, Wu ZJ, Burgreen GW, Antaki JF. Application of bioluminescent

plankton for shear stress measurement within circulatory assist components. Proc Int Conf

on Cardiac Mechanics in Medicine and Biology, Hawaii, 1998.

4. Wu ZJ, Burgreen GW, Thomas D, Butler KC, Griffith BP and Antaki JF. Visualization of

Flow Features in a Miniature Axial Flow Blood Pump Using Laser-Based Fluorescent Particle

Imaging Technique. Proceedings of the 8th International Symposium on Flow Visualization,

paper 112, Italy, September 1998.

5. Gottlieb RK, Wu ZJ, Borovetz HS and Antaki JF. Calibration of a Novel Liquid Crystal

Shear Stress Sensor. Proceedings of the 8th International Symposium on Flow Visualization,

paper 113, Italy, September 1998.

6. Wu ZJ, Sturk K, Marascalco P, Marhefka, J Kameneva MV. Modification of Flow Behavior

of Red Blood Cells by Blood Soluble Drag-Reducing Polymers. Proceedings of International

Congress on Biological and Medical Engineering, Singapore, December, 2002.

7. Marascalco PJ, Pensenstadler KL, Smith GC, Baer SA, JN Marhefka, Wu ZJ, Kameneva

KV. Effect of drag reducing polymers (DRPs) on red blood cell (RBC) filterability.

Biomedical Engineering: Recent Developments. J Vossoughi (editor), 2002

8. Antaki JF, Boston JR, Simaan M, and Wu Z. Current strategies for control of turbodynamic

blood pumps. Proceedings of 2nd Joint Conference of the IEEE Engineering in Medicine and

Biology Society and the Biomedical Engineering Society, Houston, October, 2002.

9. Zhang J, Nolan TDC, Griffith BP, and Wu ZJ. Computational and In-vitro Characterization

of Pressure Drop and Oxygenation in Blood Membrane Oxygenators. Proceedings of the

American Society of Mechanical Engineers Summer Bioengineering Conference, June 22-26,

2005.

10. Zhang J, Nolan TDC, Egerton M., Griffith BP, and Wu ZJ. Numerical Prediction of Shear

Stress Induced Hemolysis in Biomedical Devices. Proceedings of the American Society of

Mechanical Engineers Summer Bioengineering Conference, June 22-26, 2005.

11. Wu ZJ, Prastein D, Kilic A, Moainie S, Egerton M, Nash JR, Sacks MS, and Griffith

BP. Strain Mapping of LVAD Unloading and Post MI Remodeling. Proceedings of the

American Society of Mechanical Engineers Summer Bioengineering Conference, June 22-26,

2005.

12. Taskin ME, Zhang T, Wu C, Griffith BP, Wu ZJ, "CFD Assisted Design of a Wearable

Artificial Pump Lung Device", Proceedings of ASME International Mechanical Engineering

Congress & Exposition, Boston, MA. Oct. 31-Nov. 6, 2008.

13. Wu C, Li T, Savai K, Griffith BP, Wu ZJ. Strain mapping of LV myocardium and its

correlation with activation of apoptotic molecular pathways post infarction. Presented at the

http://users.adelphia.net/~stnash98/AOLab/publications_files/ASME_Zhang_OXY.pdf

http://users.adelphia.net/~stnash98/AOLab/publications_files/ASME_Zhang_OXY.pdf

http://users.adelphia.net/~stnash98/AOLab/publications_files/ASME_Zhange_BD.pdf

http://users.adelphia.net/~stnash98/AOLab/publications_files/ASME_Zhange_BD.pdf

http://users.adelphia.net/~stnash98/AOLab/publications_files/ASME_Wu.pdf


ASME 2008 Summer Bioengineering Conference (SBC2008). Marriott Resort, Marco Island,

Florida, USA, June 25-29, 2008.

14. Taskin ME, Zhang T, Gellman B, Dasse KA, Griffith BP, and Wu ZJ. 3D flow modeling

and blood damage characterization of the ultramag™ blood pump. Presented at the ASME

2008 Summer Bioengineering Conference (SBC2008). Marriott Resort, Marco Island,

Florida, USA, June 25-29, 2008.

15. Taskin EM, Zhang T, Griffith BP, and Wu ZJ. Computational Analysis of a Wearable

Artificial Pump Lung Device in Terms of Rotor/Stator Interactions. The ASME 2009

Summer Bioengineering Conference, June 17 to 21, 2009, Lake Tahoe, CA.

16. Wu C, Chang WB, Gibber M, Griffith BP, Wu ZJ. Bioengineering Quantification of Left

Ventricular Remodeling Following Myocardial Infarction. The ASME 2009 Summer

Bioengineering Conference, June 17 to 21, 2009, Lake Tahoe, CA.

17. Fraser KH, Taskin ME, Zhang T, RRichardson S, Gellman B, Dasse B, Griffith BP, Wu ZJ.

The effect of impeller position on CFD calculations of blood flow in magnetically levitated

centrifugal blood pumps. Proceedings of the American Society of Mechanical Engineers

Summer Bioengineering Conference (SBC2010). June 16-19, Grande Beach Resort, Naples,

Florida, USA.

18. Taskin ME, Zhang T, Griffith BP, and Wu ZJ. Design Optimization of a Wearable Artificial

Pump-Lung Device with Computational Modeling. Proceedings of the American Society of

Mechanical Engineers Summer Bioengineering Conference (SBC2010). June 16-19, Grande

Beach Resort, Naples Florida, USA.

19. Engel E, Wu ZJ, and Griffith BP. Early Remodeling Strain Levels Can Predict The

Progression of Remodeling of The Left Ventricle Post Myocardial Infarction. Proceedings of

the American Society of Mechanical Engineers Summer Bioengineering Conference

(SBC2010). June 16-19, Grande Beach Resort, Naples, Florida, USA.

20. K H Fraser, M E Taskin, T Zhang, B P Griffith and Z J Wu Comparison of Shear Stress,

Residence Time and Lagrangian Estimates of Hemolysis in Different Ventricular Assist

Devices. 26th Southern Biomedical Engineering Conference, 2010, IFMBE Proceedings, 32,

pp 548-551

21. Zhang P, Li T, Williams K, Li S, Wei X, Son H, Sanchez P, Griffith BP, Wu ZJ. Analysis of

Mechanical Effects on Myocardial Infarction Remodeling. Proceedings of the ASME 2011

Summer Bioengineering Conference, June 22-25, 2011, Farmington, PA.

22. Fraser KH, Zhang T, Griffith BP, Wu ZJ. Differences in Shear Stress, Residence Time and

Estimates Of Hemolysis between Different Ventricular Assist Devices. Proceedings of the

ASME 2011 Summer Bioengineering Conference, June 22-25, 2011, Farmington, PA.

23. Zhang J, Zhang P, Fraser K, Griffith BP, Wu ZJ. Experimental Validation of Fluid Dynamic

Numerical Models in Blood Pump Simulation. Proceedings of the ASME 2012 Summer

Bioengineering Conference, (SBC2012), June 20-23, Fajardo, Puerto Rico, USA.

Published Abstracts and Conference Presentations

1. Wu ZJ, Ren Q, Simom G, Parel J-M. Photo-thermal Modeling Biomechanics of Laser

Photo-thermal Keratoplasty (LPTK). Presented at ARVO Annual Meeting May 1993.

Sarasota, Florida.


2. Menon S, Li W, Wu ZJ, Haubold A and Hwang NH. A Long Body Mechanical Heart

Valve for Improved Hydrodynamic Performance. Presented at BMES 1993 Annual Fall

Meeting, Memphis, October 21-24, 1993.

3. Wang SK, Wu ZJ, Wang Y and Hwang NH. Deceleration of Bileaflet MHV at Closing

and Transient Pressure Reduction. Presented at BMES 1993 Annual Fall Meeting,

Memphis, October 21-24, 1993.

4. Wu ZJ, Menon S and Hwang NH. Impact and Rebound of Mechanical Heart Valve

(MHV) Leaflets at Closing. Presented at BMES 1993 Annual Fall Meeting, Memphis,

October 21-24, 1993.

5. Wang Y, Wu ZJ and Hwang NH. Squeeze Flow Fields at the Closing of Mechanical

Heart Valves. Presented at Second World Congress of Biomechanics. Amsterdam, the

Netherlands, July 10-15, 1994.

6. Salat O, Wu ZJ, Glismann CC and Hwang NH. Adjustable Preload and Afterload for

Mock Flow Loop Testing of Prosthetic Heart Valves. Presented at Second World

Congress of Biomechanics. Amsterdam, the Netherlands, July 10-15, 1994.

7. Hwang NH, Wu ZJ and Fung KY. Mechanical Heart Valve Closing Velocity and

Cavitation Potential. Presented at the Second Sheffield Symposium of Heart Valve

Replacement. Sheffield, UK, October 1994.

8. Wu ZJ and Hwang NH. Mounting Orientations and The Closure Behavior of a

Monoleaflet Mechanical Heart Valve. Presented at 1994 BMES Annual Meeting, Tempe,

Arizona, October 14-16, 1994.

9. Wu ZJ, Wang SK and Hwang NH. Regurgitant Jet Profiles in Asynchronous Closure of

Bileaflet Mechanical Heart Valves. Presented at ASAIO 1995 Annual Meeting, Chicago,

May 4-6, 1995.

10. Wu ZJ, Gao BZ, Ritter C and Hwang NH. Effect of Housing Compliance on Mechanical

Heart Valve (MHV) Transient Pressure at Closing. P resented at 1995 BMES Annual

Meeting, Boston, October 6-8, 1995.

11. Wu ZJ, Gao BZ, Slonin JH and Hwang NH. Performance of Bileaflet Mechanical Heart

Valves at Low Cardiac Output,” Presented at ASAIO 1996 Annual Meeting, Washington,

DC, May 1996.

12. Wu ZJ, Slonin JH and Hwang NH. Transient Pressure Signals as A Means in Measuring

Mechanical Heart Valve Cavitation Potential. Presented at 1996 Fall BMES Annual

Meeting, State College, PA, October 2-4, 1996.

13. Antaki JF, Paden BE, Gurgreen GW, Groon NJ, Kameneva MV, Wu Z, Holmes JA and

Griffith BP. The ‘Streamliner’: a New Mixed Flow Blood Pump with Magnetic Bearings.

Presented at 5th Congress of the International Society for Rotary Blood Pumps. Marseille,

France, September 1997.

14. Antaki JF, Choi S, Thomas D, Amin D, Litwak P, Wu ZJ and Boston RJ. In Search of ...

Hemodynamic Control for Rotary Blood Pumps 2: Architecture, Algorithms, and

Setpoints. Presented at 5th Congress of the International Society for Rotary Blood Pumps.

Marseille, France, September 1997.

15. Wu ZJ and Hwang NH. Cavitation in Mechanical Heart Valves: A Squeeze Flow

Phenomenon. Presented at 1997 BMES Annual Meeting, San Diego, CA, October 1997.

16. Curtis AS, Wu ZJ, Antaki JF. Transparent Compliant Left ventricle for Flow

Visualization of Apical Cannulation. Presented at 1997 BMES Annual Meeting, San


Diego, CA, October 1997.

17. Lardo AC, Webber SA, Wu ZJ, Friehs I, del Nido PJ, Cape EG. Effect of accessory

pulmonary blood flow in the bidirectional superior vena cava anastomosis: a quantitative

fluid dynamics study. Presented at the American Heart Association 70th Scientific

sessions. Orlando, FL. November 1997.

18. Curtis AS, Meyer RK, Wu ZJ, Burgreen GW and Antaki JF. Application of

Bioluminescent Plankton for Shear Stress Measurement within Circulatory Assist

Components. Presented at International Conference on Mechanics in Medicine and

Biology, Honolulu, Hawaii, March 1998.

19. Burgreen GW, Antaki JF, Wu ZJ, LeBlanc P, Butler KC, Kormos, RL. A computational

and experimental comparison of two outlet stators for the Nimbus LVAD. In: The 44th

Meeting of the American Society of Artificial Internal Organs. New York NY, April 23-

25, 1998.

20. Amin D, Antaki JF, Litwak P, Thomas D, Wu ZJ, Watach M, Butler KC. Introduction of

ventricular collapse by axial flow blood pump. IN: The 44th Meeting of the American

Society of Artificial Internal Organs. New York NY, April 23-25, 1998.

21. Wu ZJ, Antaki JF, Burgreen GW, Butler K, Thomas D, and Griffith BP. Fluid dynamic

characterization of operating conditions for continuous flow blood pumps. In: The 44th

Meeting of the American Society of Artificial Internal Organs. New York, NY, April 23-

25, 1998.

22. Antaki JF, Paden BE, Gurgreen GW, Kameneva MV, Wu ZJ, Holmes JA, Paden D,

Groom NJ, and Griffith BP. Development Progress of the Streamliner Mixed Flow Blood

Pump with Magnetic Bearings. Presented at 6th Congress of the International Society for

Rotary Blood Pumps. Utah, July 1998.

23. Antaki JF, Wu ZJ, Gurgreen GW, Sorensen EN, Holmes JA and Griffith BP. Fluid

Dynamic Phenomena within A magnetically Levitated Mixed Flow Blood Pump.

Presented at the Third World Congress of Biomechanics. Sapporo, Japan, August 1998.

24. Wu ZJ, Kameneva MV, Repko BM, Butler KC and Antaki JF. Relationship between

fluid dynamics and hemolysis of an axial flow blood pump. The 1998 BMES annual

meeting, Cleveland, OH, October 1998.

25. Lardo AC, Webber SA, Iyenagar A, Wu Z, Friehs I, del Nido PJ, Cape EG. Pulmonary

flow dynamics of the bidirectional superior cavopulmonary anastomisis with accessory

main and aortopulmonary flow sources. The American Heart Association 71st Scientific

sessions. November 1998, Dallas, TX.

26. Iyengar AK, Park SC, Wu ZJ, Neches WH. Hemodynamic considerations in the genesis

of coarctation of aorta: an in vitro study of fetal cardiac circulation. American Society of

Echocardiography: 10th Annual Scientific Sessions, Washington, DC, June 1999.

27. Wu ZJ, Antaki JF, Ewing B, Kameneva MV, Repko BM, Thomas DC, Butler KC.

Operating range for axial flow blood pump: relationship of fluid dynamics, efficiency, and

hemolysis. In: The 44th Meeting of the American Society of Artificial Internal Organs.

San Diego, CA, June 2-5, 1999.

28. Antaki JF, Wu J, Boston, Baloa L, Choi S, Litwak K, Litak P, L McCue, Thomas, D, Butler

KC. In continued search of … control for turbodynamic blood pumps. In: The 44th

Meeting of the American Society of Artificial Internal Organs. San Diego, CA, June 2-5,

1999.


29. Antaki JF, Gurgreen GW, Wu ZJ, Borzelleca D, Kameneva MV, Holmes JA, Litwak P,

Litwak K, Watach M, Paden BE, Dragnes T, Groom NJ and Griffith BP. Development

Progress of the University of Pittsburgh Streamliner: a Mixed Flow Blood Pump with

Magnetic Bearings. Presented at In: The 46th Meeting of the American Society of

Artificial Internal Organs. New York, NY, June 28-July1, 2000.

30. Butler K, Thomas D. Taylor L, Petersen T, Poirier V, Parsaie F, Kormos R, Borovetz H,

Litwak P, Litwak K, Kameneva M, Wu J, Antaki J, Watach M. The Heartmate II Axial

flow LVAS: Journey towards Clinical Trial. In: The 46th Meeting of the American

Society of Artificial Internal Organs. New York, NY, June 28-July1, 2000.

31. Wu ZJ, Holmes JA, Griffith BP, Gartner MJ. Flow Dynamics of an Active Mixing

Pump-Oxygenator. The 47th Meeting of the American Society of Artificial Internal

Organs. New York, NY, June 28-July1, 2000.

32. Gottlieb R, Antaki J, Wu Z, Griffith BP. Visualization of wall shear stress in blood-

wetted artificial organs using new photochromic liquid crystal sensor. The 47th Meeting

of the American Society of Artificial Internal Organs. New York, NY, June 28-July1,

2000.

33. Antaki JF, Liu Y, and Wu ZJ. Cannula design can reduce regurgitant flow during VAD

stoppage: when a check valve is not a check valve. The 47th Meeting of the American


34. Snyder TA, Wu J, Antaki JF, Burgreen GW, Wagner WR. In vitro investigation of shear-

induced platelet activation in axial flow VADS. The 47th Meeting of the American


35. Kihara S, Litwak KN, Litwak P, Nichols L, Wu ZJ, Kormos L. Lower assist rate is

associated with pathology of renal cortex arteries with continuous flow left ventricular

assist in calves. Presentation at ASAIO Annual Meeting, New York, NY, June 13-15,

2002.

36. Litwak KN, Wu ZJ, Kihara S. Altered Aortic hemodynamics with Continuous VAD

Support. Presentation at ASAIO Annual Meeting, New York, NY, June 13-15, 2002.

37. Antaki JF, Boston JR, Simaan M, Wu ZJ. Current Strategies for Control of

Turbodynamic Blood Pumps. Presented at 2nd Joint Conference of the IEEE Engineering

in Medicine and Biology Society and the Biomedical Engineering Society, Houston, TX,

October 2002

38. Wu ZJ, Antaki JF, Litwak K, Kameneva MV, Borovetz HS, Kormos R. Ventricular

assist devices: current status and future perspective. World Congress for Chinese

Biomecial Engineers, Taipei, Taiwan, December 2002.

39. Wu ZJ, Marascalco P, Marhefka J, Kameneva MV. Increased Red Blood Cell

Deformation by Minute Concentrations of Blood Soluble Drag-Reducing Polymers

(DRPs). ASAIO-ISAO Joint Conference. Washington DC, June 19-21, 2003.

40. Litwak KN, Kihara S, Wu Z, Sinha A, Lohman D and Koenig S. Pulsatile and

continuous flow vad aortic hemodynamics: outflow graft location is the key. ASAIO-

ISAO Joint Conference. Washington DC, June 19-21, 2003.

41. Antaki JF, Ludlow JC, Miles SD, Wu J, Burgreen GW, Wu Z, Khanwilkar P, Long J.

Low-profile inlet for centrifugal pump. ASAIO-ISAO Joint Conference. Washington

DC, June 19-21, 2003.


42. Marascalco PJ, Marhefka J, Wu Z, Kameneva M. Effect of drag reducing moplymer

(DRPs) on red blood cell (RBC) filterability. ASAIO-ISAO Joint Conference.

Washington DC, June 19-21, 2003.

43. Hildebrand D, Wu J, Mayer J, Sacks M. Development and Evaluation of a Novel

Pulsatile Flow Loop for Biologically Active Heart Valves. Society for Heart Valve

Disease 2nd Biennial Meeting, Paris, France, June 28 – July 1, 2003.

44. Wu ZJ, Zhao R, Fu A, Marascalco P, Antaki JF and Kameneva MV. Effect of Drag

Reducing Polymers On Microscale Flow Behavior Of Red Blood Cells. Second

International Interdisciplinary Conference on Cardiovascular Medicine and Science,

Bethesda, Maryland. July 23-25, 2003.

45. Wu ZJ, Zhao R, Kameneva MV and Antaki JF. Blood Cell Tracking Velocimetry for

Studying Flow-Induced Blood Damage Dynamics. Second International Interdisciplinary

Conference on Cardiovascular Medicine and Science, Bethesda, Maryland. July 23-25,

2003.

46. Wu ZJ, Marascalco PJ, Smith GC, Marhefka JN, and Kameneva MV. Effect of drag-

reducing polymers on red blood cells in microchannel flow. 75th Annual Meeting of the

Society of Rheology. Pittsburgh, PA, October, 2003.

47. ZJ Wu, WJ Federspiel. DPIV flow study of a pulsating artificial lung catheter. ASAIO

50th Anniversary Conference, Washington DC, June 17-19, 2004

48. Zhao R, Antaki JF, Wu ZJ, Kameneva MV, Bachman T. Investigation of microscale

blood flow behavior and shear-induced blood damage by cell tracking velocimetry.

ASAIO 50th Anniversary Conference, Washington DC, June 17-19, 2004

49. Dague C, Bourgue K, Loree H, Farrar D, Gurgreen G, Hampton E, Fleischli A, Gempp T,

Schoeb R, Wu ZJ, K Litwak K, Watach M, Tamez D, Gregoric ID, Clubb FJ, Frazier

OH. CFD and flow visualization analyses of critical gaps in a rotary pump, with in vivo

corroboration. ASAIO 50th Annual meeting, Washington DC, June 17-19, 2004.

50. Zhao R, Antaki JF, Wu ZJ, Diao C, Kameneva MV. Red Blood Cell Response to Supra-

physiologic Shear Stress in Micro-channels with Different Geometries. Presented at 2004

BMES Annual Meeting, Philadelphia, PA, Oct 13 ~16, 2004

51. Wu ZJ, Zhang JT, Nolan TD, Chambers S, and Griffith BP. Development of a Novel

Integrated Pump Oxygenator. Presented at the American Society for Artificial and

Internal Organs 51st Annual Conference, Washington DC, June 9-11, 2005.

52. Zhang J, Nolan TDC, Griffith BP, and Wu ZJ. Prediction of Oxygenation, Hemolysis

and Thrombosis in Blood Membrane Oxygenators Using Computational Fluid Dynamics.

Presented at the American Society for Artificial and Internal Organs 51st Annual

Conference, Washington DC, June 9-11, 2005.

53. Prastein DJ, Kilic A, Ayala T, Wu ZJ, and Griffith BP. Myocardial Strain Map of

Remodeling. Presented at the American Society for Artificial and Internal Organs 51st

Annual Conference, Washington DC, June 9-11, 2005.

54. Kilic A., Prastein D.J., Schwartzbauer G., Wu ZJ, and B.P. Griffith. Regional SERCA2a

Protein Expression in the Post-MI Model of Heart Failure. Presented at the American

Society for Artificial Internal Organs 51st Annual Conference, Washington DC, June 9-

11, 2005

55. Nash JR, Kilic A, Prastein D, Li T, Nolan TDC, Schwartzbauer G, Griffith BP, and Wu

ZJ. Left Ventricular Regional Strains and Protein Expression Predict Remodeling Post

http://www.icr-heart.com/biennial2003/files/16837.doc

http://www.icr-heart.com/biennial2003/files/16837.doc

http://www.rheology.org/sor03a/abstract.asp?PaperID=263

http://www.rheology.org/sor03a/abstract.asp?PaperID=263

http://users.adelphia.net/~stnash98/AOLab/publications_files/ASAIO-Strain%20Map_Prastein.pdf

http://users.adelphia.net/~stnash98/AOLab/publications_files/ASAIO-Strain%20Map_Prastein.pdf

http://users.adelphia.net/~stnash98/AOLab/publications_files/ASAIO-SERCA2a_Kilic.pdf

http://users.adelphia.net/~stnash98/AOLab/publications_files/ASAIO-SERCA2a_Kilic.pdf

http://users.adelphia.net/~stnash98/AOLab/publications_files/BMES_Nash.pdf


Myocardial Infarction. Presented at the Biomedical Engineering Society Annual Fall

Meeting, September 28-October 1, 2005

56. Zhang J, Griffith BP, and Wu ZJ. CFD Based Multi-objective Analysis and

Optimization of Blood Oxygenating Devices. Presented at the Biomedical Engineering

Society Annual Fall Meeting, September 28-October 1, 2005

57. Kilic A, Li T, Nash J, Prastein D, Schwartzbauer G, Nolan T, Wu Z, Griffith B. Strain

Related Regional Alteration of Sarcoplasmic Reticulum ATPase in Heart Failure. 3rd

International Congress, The Failing Heart Under Stress, Amsterdam, Netherlands,

November 2005.

58. Li T, Kilic A, Nash J, Prastein D, Schwartzbauer G, Nolan T, Wu Z, Griffith B. Strain

Related Alterations of the Phosphoinositide 3-Kinase / Akt / BAD Survival Pathway.

JACC Supp 2006 47 (Issue 4, Supp. 1): 76A.

59. Kilic A, Li T, Nash JR, Prastein DJ, Schwartzbauer G, Nolan TDC, Wu Z, Griffith BP.

Strain Related Regional Alterations of Calcium Handling Proteins in Heart Failure.

American Association for Thoracic Surgery. 86th Annual Meeting, Philadelphia, PA,

April 2006.

60. Kilic A, Nash J, Li T, Prastein D, Schwartzbauer G, Nolan T, Wu Z, Griffith B.

Mechanical Unloading of the Failing Heart Restores Strain Related Calcium Handling

Protein Expression. J Heart Lung Trans Supp 2006 25 (Issue 2, Supp. 1): S103.

61. Kilic A, Nolan TDC, Li T, Yankey GK, Prastein DJ, Jarvik R, Wu Z, Griffith BP.

Chronic In-Vivo Hemodynamic Study of the Pediatric Jarvik 2000 Heart. 52nd Annual

ASAIO Conference, Chicago, IL, June 2006.

62. Wu ZJ, Kilic A, Nolan TDC, Li T, Yankey GK, Jarvik R, Griffith BP. Compensatory

Hemodynamic and Biologic Responses to Pediatric Circulatory Support in Lambs. 52nd

Annual ASAIO Conference, Chicago, IL, June 2006.

63. Wu ZJ, Zhang J, Nolan TDC, Zhang T, Griffith BP. Computational and experimental

evaluation of an integrated blood pump oxygenator. Presentation at 5th World Congress of

Biomechanics, Munich, Germany, July 28 ~ August 4, 2006.

64. Zhang J, Zhang T, Nolan TDC, Griffith BP, Wu ZJ. Toward a Multi-Objective Model for

Artificial Lung Devices. Presentation at 5th World Congress of Biomechanics, Munich,

Germany, July 28 ~ August 4, 2006.

65. Kilic A, Yankey GK, Nolan TDC, Li T, Cheng G, Wu Z, Griffith BP. Regional Systolic

and Remodeling Strain Differences during Cardiac Remodeling. American College of

Surgeons 92nd Annual Clinical Congress, Chicago, IL., October, 2006

66. Wu ZJ, Kilic A, Zhang J, Burgreen G, Cheng G, Yankey GK, Li T, Jarvi RK, Griffith

BP. Progress and Initial In-Vivo Experience of the Pediatric Jarvik 2000 Hearts. ISHLT,

2007, San Francisco.

67. Yankey GK, Li T, Kilic A, Moainie S, Weidenhamer N, Nolan T, Cheng G, Prastein D,

Schwartzbauer G, Wu ZJ, Griffith BP. Regional Remodeling Strain and Its Association

with Myocardial Apoptosis Post-Myocardial Infarction in Ovine Model. 87th Annual

American Association for Thoracic Surgery Meeting, Washington, D.C.; May 2007

68. Yankey GK, Nolan T, Wu ZJ, Griffith BP, Gammie JS. Epicardial Cryoablation Reliably

Produces Transmural Lesions on the Beating Heart. ISMICS, Rome, Italy, June, 2007

69. Zhang J, Koert A, Zhang T, Gellman B, Dasse KA, Gilbert RJ, Griffith BP, Wu ZJ.

Computational Fluid Dynamics Analysis of an Integrated Maglev Pump-Oxygenator

http://users.adelphia.net/~stnash98/AOLab/publications_files/BMES_Nash.pdf


(IMPO). Presented at 53rd ASAIO Annual Conference, June 7-9, 2007 - Chicago, IL

70. Wu ZJ, Gellman B, Zhang J, Koert A, Zhang T, Dasse KA, Griffith BP. An Integrated

Maglev Pump-Oxygenator (IMPO). Presented at 53rd ASAIO Annual Conference, June

7-9, 2007 - Chicago, IL

71. Wu ZJ, Li T, Yankey GK, Kilic A, Cheng G, Savai K, Griffith BP. LV regional strains

and activation of molecular survival and apoptotic pathways post myocardial infarction.

Presentation at BMES 2007 Annual Fall Meeting, Los Angeles, CA, September 26-29,

2007.

72. Zhang T, Zhang J, Nolan TDC, Griffith BP, Wu ZJ. Benchmark Study of Oxygen

Transfer in Microporous Hollow Fiber Membrane (HFM) Bundles. Presentation at BMES

2007 Annual Fall Meeting, Los Angeles, CA, September 26-29, 2007.

73. Yankey GK, Li T, Kilic A, Savai K, Cheng G, Satpute A, Wu ZJ, Griffith BP. Strain

Related Changes in Regional Myocardial Cyclin-Dependent Kinase (Cdk) Inhibitor

Protein, p21 Post-Myocardial Infarction in Ovine Model. American College of Surgeons,

Meeting, New Orleans, LA, October 2007

74. Cheng G, Farnan R, Jarvik RK, Griffith BP, Wu ZJ. In Vivo Experience with Different

Types of Assist Devices for Heart Unloading. Presented at the 54th ASAIO Annual

Conference, San Francisco, CA. June 19-21, 2008.

75. Zhang T, Griffith BP, Wu ZJ. Characterization of hollow fiber membrane bundles in

benchmrak test. Presented at the 54th ASAIO Annual Conference, San Francisco, CA.

June 19-21, 2008.

76. Taskin ME, Zhang T, Gellman B, DasseKA, Griffith BP, and Wu ZJ. Computational

flow and blood damage modeling of the ultramag™ blood pump. Presented at the 54th

ASAIO Annual Conference, San Francisco, CA. June 19-21, 2008.

77. Zhang T, Wu C, Snyder T, Jarvik R, Griffith BP, Wu ZJ. Study of blood damage using a

newly developed blood shearing device. Presented at the 54th ASAIO Annual

Conference, San Francisco, CA, June 19-21, 2008.

78. Savai K, Wu C, Farnan R, Cheng G, Morley D, Griffith BP, and Wu ZJ. The Impact of

Partial Circulatory Support on the Strain Distribution on the Post-Infarction Left

Ventricular Wall. Presented at the 54th ASAIO Annual Conference, San Francisco, CA,

June 19-21, 2008.

79. Gao Y, Savai K, Li T, Wu C, Bond M, Wu ZJ, Griffith BP. Expression of Akt/Pim-1

Survival Proteins in Myocardial Remodeling. Basic Cardiovascular Sciences Conference

2008 - Heart Failure: Molecular Mechanisms and Therapeutic Targets. Keystone, CO, Jul

28-31, 2008.

80. Li T, Savai K, Wu C, Yankey GK, Cheng G, DeFilippi C, Bond M, Wu ZJ, Griffith BP.

Strain Activation of Calcineurin-Mediated Mitochondria Apoptotic Pathway after

Myocardial Infarction in Ovine Model. Basic Cardiovascular Sciences Conference 2008 -

Heart Failure: Molecular Mechanisms and Therapeutic Targets. Keystone, CO, Jul 28-31,

2008

81. Wu ZJ, Wilson A, Wu C, Veirs M, Chang WB, Savai K, Macvittie T, Griffith BP.

Transplantation of Mesenchymal Stem Cells Improves Myocardial Infarct Border Zone

Contractility. BMES Annual Fall Meeting, St. Louis, MO. October 2-4, 2008.

82. Taskin ME, Zhang T, Griffith BP, Wu ZJ, "A Combined CFD-based hemolysis

Prediction Approach for Biomedical Devices", BMES Annual Fall Meeting, St. Louis,


MO. October 2-4, 2008.

83. Taskin ME, Zhang T, Griffith BP, Wu ZJ. Micro-Scale Modeling of Flow through

Hollow Fiber Membrane. The 55th ASAIO Annual Conference, Dallas, TX, May 28-30,

2009.

84. Jarvik R, Wu ZJ, Griffith BP. Cone Bearings Enable Sub-Miniature Permanent Blood

Pumps. The 55th ASAIO Annual Conference, Dallas, TX, May 28-30, 2009.

85. Zhang T, Taskin T, Wong T, Biancucci B, Wu ZJ, Griffith BP. Development of a

Wearable Pump-Lung. The 55th ASAIO Annual Conference, Dallas, TX, May 28-30,

2009.

86. Fraser KH, Mihelc K, Gellman B, Dasse K, Griffith BP, Wu ZJ. CFD Analysis of

Thrombosis Potential in LVAD Drainage Cannulation. The 55th ASAIO Annual

Conference, Dallas, TX, May 28-30, 2009.

87. Gibber M, Chang WB, Hu J, Savai K, Jarvik R, Wu ZJ, Griffith BP. Pediatric Jarvik

2000 Heart Experience Update. The 55th ASAIO Annual Conference, Dallas, TX, May

28-30, 2009.

88. Wu C, Chang WB, Gibber M, Wu ZJ, Griffith BP. Acute Left Ventricular Unloading by

the Impella VAD. The 55th ASAIO Annual Conference, Dallas, TX, May 28-30, 2009.

89. Zhang T, TaskinM, Gellman B, Dasse K, Griffith BP, Wu ZJ. Link of Fluid Dynamic

Variables to Hemolysis in Blood Pumps. The 55th ASAIO Annual Conference, Dallas,

TX, May 28-30, 2009.

90. Jarvik R, Wu Z, Sherman C, Kavala L, and Griffith B. Summary at Completion of the

Jarvik 2000 NIH Pediatric Development Program. The Fifth International Conference on

Pediatric Mechanical Circulatory Support Systems and Pediatric Cardiopulmonary

Perfusion, Dallas, TX, May 28-30, 2009.

91. Farnan GG, Marsille O, Kerkhoffs W, Farnan RC, Wu C, Wu ZJ, Griffith BP. Pediatric

Application of the CircuLite Synergy Micro-Pump Technology. The Fifth International

Conference on Pediatric Mechanical Circulatory Support Systems and Pediatric

Cardiopulmonary Perfusion, Dallas, TX, May 28-30, 2009.

92. Taskin ME, T Zhang, BP Griffith, and Wu ZJ. Computational and Experimental

Evaluation of an Artifical Pump-Lung Device. FDA / NHLBI / NSF Workshop on

Computer Methods for Cardiovascular Devices, June 1-2, 2009, Bethesda, Maryland.

93. Fraser KH, Taskin ME, Zhang T, Griffith BP, and Wu ZJ. The Influence of Taylor

Vortices in Centrifugal Ventricular Assist Devices on Blood Damage Potential.

FDA/NHLBI/NSF Workshop on Computer Methods for Cardiovascular Devices, June 1-

2, 2009, Bethesda, Maryland.

94. Wu ZJ, Gellman B, Zhang T, Mihelc K, Gibber M, Chang WB, Taskin M, Garcia J,

Dasse K, Griffith BP. Chronic In-vivo Performance of Pediatric Pump-Lung (PediPL) for

Cardiopulmonary/Circulatory Support. 2009 Biomedical Engineering Society Annual Fall

Meeting, Pittsburgh, October 7-10, 2009.

95. Wu ZJ, Zhang T, Taskin ME, Bianchi G, Wong P, Biancucci B, Griffith BP. An

Ultracompact Integrated Magnetically Levitated Pump-Lung for

Cardiac/Cardiopulmonary Support. 17th Congress of the International Society of Rotary

Blood Pumps (ISRBP). October 1 to 3, 2009, Singapore.

96. Fraser KH, Zhang T, Taskin ME, Chen C, Griffith BP, Wu ZJ. Design of a New Mag-

Lev Hemolyzer using CFD. The 56th ASAIO Annual Conference, Baltimore, MD, May


27-29, 2010

97. Taskin ME, Zhang T, Gellman B, Dasse KA, Griffith BP, and Wu ZJ. Computational

evaluation of the pediatric scaled pump-lung (PediPL) device. The 56th ASAIO Annual

Conference, Baltimore, MD, May 27-29, 2010.

98. Engel E, Wei X, Bianchi G, Son HS, Griffith BP, Wu ZJ. Impella LVAD Effectively

Decreases Strains in Left Ventricle after Myocardial Infarction. The 56th ASAIO Annual


99. Bianchi G, Wei X, Li T, Engel E, Son HS, Wu ZJ, Griffith BP. Early unloading of

infarcted hearts prevents cardiac remodeling and preserves calcium homeostasis. The

56th ASAIO Annual Conference, Baltimore, MD, May 27-29, 2010.

100. Zhang T, Bianchi G, Gellman B, Dasse K, Garcia J, Wu ZJ, Griffith BP. 30 Day In-Vivo

Performance of an Integrated Pediatric Pump-Lung for Cardiac/Cardiopulmonary

Support. The 56th ASAIO Annual Conference, Baltimore, MD, May 27-29, 2010.

101. Zhou K, Hu J, Griffith BP, Wu ZJ. Evaluation of Platelet Activation in Ovines Implanted

with Integrated Pump-Lung Using Soluble P-Selectin. The 56th ASAIO Annual


102. Kon ZN, Tendukular A, Wu ZJ, Iacono A, McCormick B, Griffith BP, Garcia JP. Extra

Corporeal Membrane Oxygenation via cannulation of the internal jugular vein with a

dual-lumen Single Catheter System: A novel Approach for treatment of End-Stage Lung

Disease, 90th Annual American Association for Thoracic Surgery Meeting, Toronto, ON,

Canada; May 2010

103. Taskin ME, Zhang T, Fraser KH, Griffith BP, and Wu ZJ. Evaluation of Power-Law

Hemolysis Prediction Models. FDA/NHLBI/NSF Workshop on Computer Methods for

Cardiovascular Devices, June 10-11, 2010, Bethesda, Maryland.

104. Fraser KH, Taskin ME, Zhang T, Griffith BP, Wu ZJ. Comparison of Shear Stresses and

Residence Times in Different Ventricular Assist Devices. FDA/NHLBI/NSF Workshop

on Computer Methods for Cardiovascular Devices, June 10-11, 2010, Bethesda,

Maryland.

105. Griffith BP, Drummond A, Farnan R, Wu Z, Zhang T, Budris J, and Farnan G.

Feasibility of CircuLite’s Circulatory Support System in Children. The Sixth International

Conference on Pediatric Mechanical Circulatory Support Systems and Pediatric

Cardiopulmonary Perfusion, Boston, May, 2010.

106. Wei X, Li T, Williams K, Bianchi G, Son HS, Li S, Wu ZJ, Griffith BP. Unloading with

left ventricular assist devices protects heart function by normalizing alterations of calcium

handling proteins after myocardium infarction. Presentation at AHA Scientific Sessions

2010, Chicago, IL, Nov. 13-17, 2010.

107. Wu ZJ, Gellman B, Zhang T, Dasse K, Garcia JP and Griffith BP. An Integrated

Pediatric Pump-Lung for Cardiac/Cardiopulmonary Support. ISHLT 31st Annual Meeting

and Scientific Sessions, April 13-16, 2011 San Diego, CA, USA.

108. Fraser K, Zhang T, Sorensen E, Hu J, Williams K, Feller E, Garcia J, Griffith B, Wu ZJ.

Mechanical Blood Damage in an Axial VAD compared to a Centrifugal VAD. ISHLT

31st Annual Meeting and Scientific Sessions, April 13-16, 2011 San Diego, CA, USA.

109. Wei X, Son H, Sanchez PG, Zhang P, Wu ZJ, Jarvik R, Griffith BP. Acute

Hemodynamic Evaluation of the Infant Jarvik Heart in a Piglet Animal Model.

Presentation at the 57th ASAIO Annual Conference, Washington DC, June 10 -12, 2011.


110. Garimella N, Zhang T, Griffith BP, Wu ZJ. Prior Evaluation of Heparinized Hollow

Fiber Membrane Sample Surfaces. Presentation at the 57th ASAIO Annual Conference,

Washington DC, June 10 -12, 2011.

111. Fraser KH, Zhang T, Griffith BP, Wu ZJ. Larger Shear Stresses In Axial VADs Account

for Their Increased Hemolysis Risk Compared With Centrifugal VADs. Presentation at

the 57th ASAIO Annual Conference, Washington DC, June 10 -12, 2011.

112. Wu ZJ, Gellman BN, Zhang T, Wei X, Son H, Sanchez P, Vafiades D, Dasse K and

Griffith BP. Pre-Clinical Program of the Integrated Pediatric Pump-Lung (PediPL) for

Kids, Infants and Neonates. Presentation at the 57th ASAIO Annual Conference,


113. Zhang T, Fang HB, Jarvik J, Griffith BP, Wu ZJ. Study of Shear-induced Blood Damage

in Different Species. Presentation at the 57th ASAIO Annual Conference, Washington

DC, June 10 -12, 2011.

114. Zhou K, Niu S, Griffith BP, Wu ZJ. High Shear-short exposure time induced platelets

activation in different species. Presentation at the 57th ASAIO Annual Conference,


115. Hu J, Sorensen E, Feller E, Griffith BP, Wu ZJ. Evaluation of Contributing Factors to

Nonsurgical Bleeding in Continuous-flow Left Ventricular Assist Device (CF-LVAD)

Recipients. Presentation at the 57th ASAIO Annual Conference, Washington DC, June 10

-12, 2011.

116. Wei X, Li T, Williams K, Bianchi G, Son HS; Li S, DeFilippi C, Wu ZJ, Griffith BP.

Early short-term unloading with left ventricular assist device reduces regional

hypertrophy after myocardium infarction via multiple pathways. American Heart

Association (AHA) Scientific Session 2011, Orlando, Florida.

117. Wei X, Li T, Williams K, Bianchi G, Son HS; Li S, DeFilippi C, Wu ZJ, Griffith BP.

Short-term Mechanical Unloading by left ventricular assist device reduces infarct size and

prevents adverse remodeling after MI. The American College of Cardiology’s (ACC's)

61st Annual Scientific Session 2012, Chicago, Illinois.

118. Wei X, Li T, Son HS; Li S, Wu ZJ, Griffith BP. Mechanical circulatory support to a

failing Fontan circulation in a piglet animal model. Presentation at American Society of

Artificial Internal Organs (ASAIO) 58th Annual Conference, San Francisco, California,|

June 13-16, 2012.

119. Wei X, Li T, Son HS; Li S, Wu ZJ, Griffith BP. The physiological effects of the artificial

pump-lung device in a ovine animal model. American Society of Artificial Internal

Organs (ASAIO) 58th Annual Conference, San Francisco, California, June 13-16, 2012.

120. Wei X, Li T, Son HS; Li S, Wu ZJ, Griffith BP. The animal model for evaluation of the

pediatric VAD. Presentation at American Society of Artificial Internal Organs (ASAIO)

58th Annual Conference, San Francisco, California,| June 13-16, 2012.

121. Fraser KH, Taskin ME, Zhang T, Griffith BP and Wu ZJ. Flow weighted residence time:

a useful indicator of hemolysis. Presentation at American Society of Artificial Internal

Organs (ASAIO) 58th Annual Conference, San Francisco, California, June 13-16, 2012.

122. Garimella N, Gellman B, Griffith BP, Wu ZJ. In-Vivo Hemocompatibility of

Heparinized Hollow Fiber Membranes of the Pediatric Pump-Lung (PediPL) Device.

Presentation at American Society of Artificial Internal Organs (ASAIO) 58th Annual

Conference, San Francisco, California, June 13-16, 2012.


123. Niu S, Zhang T, WIllaims K, Griffith BP, Wu ZJ. Shear Induced Platelet Activation And

Signal Transduction. Presentation at American Society of Artificial Internal Organs

(ASAIO) 58th Annual Conference, San Francisco, California, June 13-16, 2012.

124. Hu J, Watkins AC, Niu N, Romar L, Hiivala NJ, Fraser K, Feller ED, Griffith BP, Wu

ZJ. Mitochondrial Damage: Potential Mechanism of Platelet Dysfunction Leading to

Nonsurgical Bleeding Complications in CF-LVAD Patients. Presentation at American

Society of Artificial Internal Organs (ASAIO) 58th Annual Conference, San Francisco,

California, June 13-16, 2012.

125. Zhang J, Zhang P, Fraser KH, Griffith BP, Wu ZJ. Comparison of Fluid Dynamic

Numerical Models for a Clinical Ventricular Assist Device and Experimental Validation.

Presentation at American Society of Artificial Internal Organs (ASAIO) 58th Annual

Conference, San Francisco, California, June 13-16, 2012.

126. Grimella N, Griffith BP, Wu ZJ. Comparative Biocompatibility Assessment of Coatings

Applied On hollow Fiber Membranes of Blood Oxygenators. Presentation at American

Society of Artificial Internal Organs (ASAIO) 59th Annual Conference, Chicago, IL,

California, June 12-15, 2013.

127. Zhang J, Fraser KH, Teal J, Jarvik R, Griffith BP, Wu ZJ. Comparison of Two Impellers

for the Jarvik Infant Pump: a Computational Fluid Dynamics (CFD) Study. Presentation

at American Society of Artificial Internal Organs (ASAIO) 59th Annual Conference,

Chicago, IL, California, June 12-15, 2013.

128. Mondal NK, Sorensen EN, Hiivala N, Feller ED, Griffith BP, Wu ZJ. Higher expression

of AGNOR and NOR Associated Proteins in Blood Leukocytes of Heart Failure Patients

Supported by Continuous Flow Left Ventricular Assist Devices (LVADs). Presentation at

American Society of Artificial Internal Organs (ASAIO) 59th Annual Conference,

Chicago, IL, California, June 12-15, 2013.

129. Watkins AC, Wei X, Sanchez PG, Liu Y, Bittle GJ, Li T, Narain A, Repetto M, Faria E,

Li S, Jarvik R, Wu ZJ, Griffith BP. Evaluation of the Infant Jarvik Ventricular Assist

Device in a Chronic Juvenile Sheep Model. Presentation at the International Society for

Heart and Lung Transplantation 33rd Annual Meeting and Scientific Sessions, Montreal,

Canada, April 24-27, 2013.

130. Mondal NK, Sorensen EN, Hiivala, Feller ED, Griffith BP, Wu ZJ. Oxidative Stress

Induced DNA Damage and Repair in Heart Failure Patients Supported by Continuous

Flow Ventricular Assist Devices. Presentation at the International Society for Heart and

Lung Transplantation 33rd Annual Meeting and Scientific Sessions, Montreal, Canada,

April 24-27, 2013.

131. Pasrija C, Sanchez PG, Wu ZJ, Griffith BP. Developing a Novel Large Animal Model of

Trauma-Induced Systemic Inflammatory Response Syndrome. Presentation at Clinical

Congress 2013 of the American College of Surgeons. Washington DC, Ocb. 6-10,2013.

132. Mondal NK, Sorensen EK, Hiivala N, Feller ED, Pham S, Griffith BP and Wu ZJ.

Intraplatelet reactive oxygen species, mitochondrial damage and platelet apoptosis

augment non-surgical bleeding in heart failure patients supported by continuous-flow left

ventricular assist device (CF-LVADs). Presentation at the International Society for Heart

and Lung Transplantation (ISHLT) 34th Annual Meeting and Scientific Sessions, April

10-13, 2014, San Diego, CA.


133. Liu Y, Sanchez PG, Narain A, Wei X, Watkins AC, Wu ZJ, Griffith BP. Thirty-Day

Cardiopulmonary Support with a Novel Portable Pediatric Artificial Pump-Lung.

Presentation at the International Society for Heart and Lung Transplantation (ISHLT)

34th Annual Meeting and Scientific Sessions, April 10-13, 2014, San Diego, CA.

134. Mondal NK, Sorensen EN, Feller ED, Rajagopal K, Pham SM, Griffith BP and Wu ZJ.

Comparison of Intraplatelet Reactive Oxygen Species, Mitochondrial Damage and

Platelet Apoptosis after HeartMate II, Jarvik 2000 and HeartWare Left Ventricular Assist

Device implantation. Presentation at American Society of Artificial Internal Organs

(ASAIO) 60th Annual Conference, Washington DC, June 18-21, 2014.

135. Niu S, Griffith BP, Wu ZJ. In-Vitro Shear Stress-Induced platelet activation: Differences

between Species: Human, Ovine, and Porcine. Presentation at American Society of

Artificial Internal Organs (ASAIO) 60th Annual Conference, Washington DC, June 18-

21, 2014.

136. Zhang J, Ding J, Griffith BP, Wu ZJ. Computational Study of Blood Damage Potential in

Three Types of Hollow Fiber Membrane Bundles. Presentation at American Society of


21, 2014.

137. Liu Y, Sanchez PG, Watkins AC, Li T, Griffith BP, Wu ZJ. An Ovine Animal Model for

Long Term Evaluation of Artificial Pump Lungs. Presentation at American Society of


21, 2014.

138. Liu Y, Sanchez PG, Watkins AC, Niu S, Teal J, Jarvik R, Wu ZJ, Griffith BP. Sixty-Day

In Vivo Performance of Infant Jarvik 2000 Heart In a Juvenile Sheep Model. Presentation

at American Society of Artificial Internal Organs (ASAIO) 60th Annual Conference,

Washington DC, June 18-21, 2014.

139. Scotti C, Debus K, Horner M, Goodin M, Hariharan P, Chow R, Zhang J, and Wu ZJ.

Fluids Perspective on the CAM as Applied to Centrifugal and Axial Blood Pumps.

Presentation at ASME 2014 Verification and Validation Symposium. Las Vegas, NV.

May 7, 2014.

Invited Lectures and Talks

1. Department of Mechanical Engineering, University of Pittsburgh. “Laser-based flow

visualization in medical devices.” March 15, 2002.

2. Keynote Speaker, World Congress for Chinese Biomecial Engineers, Taipei, Taiwan.

“Ventricular assist devices: current status and future perspective”. December 4, 2002.

3. Keynote Speaker, the 2nd International Joint Congress of the International Federation for

Artificial Organs (IFAO) and Japanese Society for Artificial Organs (JSAO). Osaka,

Japan. “Progress and In-Vivo Experience of the Pediatric Jarvik 2000 Hearts”. October

29, 2007.

4. Hunter Distinguished Lecture, Department of Bioengineering, Clemson University.

“Development of an Integrated Artificial Pump-Lung: From Concept to In-vivo

Evaluation”. November 9, 2007.


5. ChBE Department Seminar, Illinois Institute of Technology. “Fluid Dynamics and

Related Phenomena in Cardiovascular Artificial Organs”. December 5, 2007.

6. Distinguished Lecture, Korea University Artificial Organ Center, Seoul, Korea.

“Development of an Ambulatory artificial pump-lung for respiratory failure and blood

pumps for reversing cardiac remodeling post myocardial infarction”. June 22, 2008.–

7. Graduate Seminar, Fischell Department of Bioengineering, University of Maryland

College Park. "Development of Artificial Pump-Lung Technology: From Concept to

Bedside". March 11, 2011.

8. Graduate Seminar, Department of Chemical and Molecular Engineering, University of

Maryland College Park. "Use of Computational Fluid Dynamics in Development of

Cardiovascular Medical Devices: From Concept to Clinical Practice". February 7, 2012.

9. Invited Speaker at ASAIO 58th Annual Conference, San Francisco, California | June 13-

16, 2012, Bioengineering Track 3: Blood Damage and Thrombosis Modeling. "Blood

Damage." June 15, 2012.

10. Invited Speaker at ASAIO 58th Annual Conference, San Francisco, California | June 13-

16, 2012, Pulmonary Track 3: New and Novel Artificial Lung Technologies. "Design and

Optimization of an Integrated Artificial Pump-Lung for Respiratory Support." June 16,

2012.

11. Featured Faculty Speaker at China Heart Congress (CHC) 2012, Beijing, August 9 to 12,

2012. "Circulatory Assist Devices for Heart Failure: from Concepts to Clinical Use."

August 9, 2012.

12. Invited Research Seminar, “Recent development in ventricular assist devices and

extracorporeal membrane oxygenation (ECMO)”. Soochow University, Cardiovascular

Research Institute. April 18, 2013.

13. Invited Speaker at the 7th Five-Continent International Symposium on Cardiovascular

Diseases. Beijing, April 19-21, 2013. “Recent Advances of Extracorporeal Membrane

Oxygenation (ECMO).” April 21, 2013.

14. Invited Speaker at ASAIO 59th Annual Conference, Chicago, Illinois, June 12-16, 2013,

Pulmonary Track 3 Evolving Technologies in Artificial Lung: “Wearable Artificial

Pump-Lung for Ambulatory Respiratory Support.” May 14, 2013.

15. Distinguished Visitor Lecture, University of Louisville, Division of Cardiothoracic

Surgery and Cardiovascular Innovation Institute. “Use of Computational Fluid Dynamics

in Development of Cardiovascular/Cardiopulmonary Medical Devices: From Concept to

Clinical Practice”. June 25, 2013.

16. Invited Speaker at US FDA Public Workshop - Methods for Thrombogenicity Testing.

“Thrombogenicity of Mechanical Circulatory Support Devices: Experience and

Challenges from Design to Clinical Use”, FDA White Oak Campus, Silver Spring, MD,

20993. April 14, 2014.


17. Invited Speaker at 7th World Congress of Biomechanics. “A Pediatric Pump-Lung

(PediPL) for Kids, Infants, and Neonates: Challenges and Progress”. Boston, MA 02215.

July 6-11,2014

18. Invited Speaker at 7th World Congress of Biomechanics. “Computational fluid dynamic

analysis and In-vivo hemodynamics of Jarvik 2000 Infant VAD”. Boston, MA 02215.

July 6-11,2014

19. Invited Speaker at 2014 BMES Annual Meeting - Biomedical Engineering Society.

“CFD-Based Multi-Objective Modeling of Artificial Lung Devices” October 22-25, 2014

in San Antonio, Texas.

20. Graduate Seminar, Department of Mechanical Engineering, University of Maryland

Baltimore County. "Development of Cardiovascular Medical Devices: From Concept to

Clinical Practice". Sept. 26, 2014

CURRICULUM VITAE Zhongjun Jon Wu, Ph.D. Professor of...

Documents

Transcript of CURRICULUM VITAE Zhongjun Jon Wu, Ph.D. Professor of...