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XLightAll in one system: small footprint enableseasy installation and avoids laboratoryreconfiguration.

XLerateImproved performance: higher throughputthan LIAISON®, long walk-away time andimproved instrument reliability.

XLellenceSafety quality, compatibility with LIAISON®.Continuous monitoring of all critical assaysteps and liquid detection by pressuresensor.

XLargeHigher number of reagents on board andnew tests available.

XLogicRemote assistance, LIS ready and open forfuture LAS connection.

DELIVERS VALUES

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Long Walk-away TimeSystem gives the user upfront estimationof the consumable volumes on boardand allows the user to increase theconsumable volumes before starting.The disposable reaction cuvettes andsample tips, the liquid and reagentsare in continuous loading and theoperator can load and unload reagentsin any moment.

New architecture,New Graphics ApproachA complete and user-friendly softwareoffers a real two-way communication.Highly secure traceability of all processes,status of reagents and consumables aswell as all the information useful to monitorwork and achieve higher effectiveness.Test profile organization, Rerun and Reflextest rules based on operator’s input.

Higher ThroughputThe throughput is optimized splittingthe pipetting phases of Reagents andSamples into different cycles. The washerand measure chambers have doublecapacity.

The incubator may host up to 80cuvettes. The throughput is optimizedfor single-step assays, keeping it as highas possible.

Throughput of the LIAISON® XL rangesfrom 50 to 90% more than that ofLIAISON®, with most 2-step assaysworking at maximum throughput.

Consistent throughput up to 180 testsper hour depending on test profilerequired.

ENHANCE YOUR LABORATORY EFFICIENCY, IMPROVED CAPACITY AND WORKFLOW

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Consumable loading

Disposable Sample Tips and reactionCuvettes in continuous loading.

Sample Area

Up to 10 racks with 12 positions eachin continuous loading. Sample rack maybe removed as soon as samplingis completed. Barcode identificationrecognizes the assay required, butmanual input is also allowed.Different tube sizes are allowed.

Starter reagents

In continuous loading.LIAISON® XL recognizes position and lotnumber of each starter bottle and uponexhaustion of a starter bottle, it switchesautomatically to the next inserted bottle.All the information is updatedautomatically during the process.

Cabinet Area

System liquid tanks in continuous loading.Solid and liquid waste allows continuousunloading.

LIAISON® XL: COMPACT A

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Touch Screen Monitor with

Integrated Keyboard

Easy-to-use software, thecommunication between operatorand instrument requires neitherkeyboard nor mouse. Our Online helpensures that the user always gets clearexplanations to each action which canbe acquired at the touch of a button.

Reagent Area

Continuous loading for all Integralreagents.Quick release features allow the operatorto replace reagents as soon as they areexhausted.

Table

Under the reagent area toplace tiny items on the table forinstant aid to the user (maximum weightcapacity of table is 2,5 kg).

AND EFFICIENT DESIGN

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Reliable performanceThe novel technical solutions and componentsenhance the system reliability.

LIAISON® XL has the following features tohelp maximize quality• Disposable pipette tips that prevent sample carryover• Clot detection• Aspiration/Dispensing verification• Automated reflex testing and auto-rerun to ensureaccuracy of results.Single-cavity reaction cuvettes can be loaded at anytime, with any orientation; cuvettes are automaticallyloaded and sorted into the instrument from the cuvettereservoir.

MaintenanceNo daily maintenance is required.The LIAISON® XL informs the user when maintenanceis due and monitors the scheduled needs automatically.If the user chooses to complete maintenance at alater time, the system allows continuation of workand traces that maintenance has not yet beencompleted.

Service Remote AccessDirect access from our central Service center to LIAISON®

XL system allows customers to obtain the fastest solutionpossible in the event of required assistance.

Sample LoadingUp 120 tubes in continuous loading optimize theworkflow.The operator can define an automatic dilution processthrough a flexible assay protocol.

INNOVATION TO MEET YOUR NEEDS

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LIAISON® XL is compatible with the reagents and formats of the menuof products currently available for LIAISON® analyzer.

Proven QualityAll components are ready to use in one integral. LIAISON® XL utilizes chemiluminescencetechnology with magnetic microparticles (MP), the same proven quality technology used forLIAISON®.

High Reagent Capacity and Complete Traceability25 reagent positions allow preparation of larger reagent volumes for medium-to large-capacitycustomers.Different reagent Integrals or multiples of the same assay can be loaded simultaneously. Uponexhaustion of one Integral, the instrument switches automatically to the next inserted reagents.LIAISON® XL recognizes position, expiration date and lot number of reagents loaded.All the information is updated automatically during the process.

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OVERVIEW

BARCODES

System descriptionThroughputTime to first resultAssays on board

Random access or batch immunoassay systemUp to 180 tests per hour25 minutes25

SAMPLES AND SAMPLE HANDLING

Sample racksSample capacityWalk-away timeStat handlingSample typeSample integrity control

Sample carryover

6-mm to 15-mm internal diameter. Up to 100-mm height120 samples, 12-position sample racks in a 10-lane sample areaApproximately 6 hoursSTAT may be assigned to any position in the sample areaSerum / plasma / urine / CSF• Pneumatic-based level sensor• Aspirated/dispensed volume detection and flagging• Clot detection and flaggingAbsent due to the use of LIAISON® XL Disposable Tips

Sample tubes (all reading typesmay be active simultaneously)Control sera

EAN / Code 128 / Code 39 / Cod-a-bar / Interleaved 2 of 5

2D barcodes recognized by hand-held scanner

REAGENTS AND REAGENT HANDLING

Reagent coolingReagent integrity control

Reagent capacity

13°C ± 2°C• Radio Frequency identification (RFID)• Automatic inventory tracking and updating to integral RFID tag• Tracking of calibration validity• Tracking of on-board stability25-position cooled storage for reagent integrals + 4 position cooledstorage for reagent ancillaries

CuvettesDisposable TipsDI WaterWash BufferSystem cleaning solution

On board capacity: 1000On board capacity: 57610-L container + 2-L reservoir10-L container + 2-L reservoir2-L container

CONSUMABLE CAPACITY

TECHNICAL SPECIFICATIONS

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Solid wasteLiquid waste

2500 Disposable tips & cuvettes,Second container allow an instrument autonomy of 15 min2 x 10-L containers

Loading/unloading ofitems during systemoperation

Includes:Sample racks/Reagent integrals/Ancillaries/Cuvettes/Disposable tips/Controlracks/Wash liquid/System liquid/Liquid waste/Solid waste/Starter reagents

Operating system MonitorGUI

Microsoft® Windows®

17" diagonal LCD touch sensitive screen• Quick access to all pages• Critical events and actions recorded• Software-guided and logged maintenance

WASTE CAPACITY

CONTINUOUS OPERATION

USER INTERFACE

RESULTS MANAGEMENT

Viewing and editing

RetestBack-upPrivacy/safety

• Results available at all times• Sort, search, filter (display customization available)• Possibility of evaluation, validation and release of results prior to printing or LIS reportingRetest always available, even automated based on predefined rulesResults can be stored manually or automaticallyCompliant with privacy/safety regulations

QUALITY CONTROL

Package

AccessRule definitions

Long-term monitoring including L-J graphs coveringWestgard & RiliBÄK rulesAccessible at all timesAvailable to users

ENVIRONMENTAL FEATURES

15-32°C10%-85% RH non condensing90-240v, 50-60 HzHeight: 59 in or 150 cmWidth: 59 in or 150 cmDepth: 36 in or 90 cmLIAISON® XL 661 lbs or 300 kg (includes Monitor & Accessories)63.9 dBA at operator normal position

Operating temperatureOperating humidityElectricalDimensions (excludes monitorand accessories)

WeightNoise

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BONE & MINERAL25-OH Vitamin D TOTALIntact PTH1-84 PTHOsteocalcinBAP OSTASE®

THYROIDTSH (3rd Gen.)Free T3Free T4T3T4hTgAnti-hTgAnti-TPO

REPRODUCTIVEENDOCRINOLOGYLHFSHProlactinProgesteroneTestosteroneEstradiolhCG/ß-hCG

CARDIAC MARKERSTroponin IMyoglobinCK-MB

DIABETESC-PeptideInsulin

SEPSISBRAHMS PCT®

ADRENAL FUNCTIONACTHCortisolDHEA-S

VIRAL HEPATITIS AND HIVHBsAgHBsAg Confirmatory testAnti-HBsAnti-HBcHBc IgMHBeAgAnti-HBeAnti-HAVHAV IgMHCV AbHIV Ab/Ag

EBVEBV IgMVCA IgGEBNA IgGEA IgG

ANAEMIAFerritin

HYPERTENSIONDirect ReninAldosterone*

GROWTHhGHIGF-I

AUTOIMMUNITYANA ScreendsDNAtTG IgAENA ScreenCardiolipin IgG, IgM

TUMOUR MARKERSCEAFree PSATotal PSACA 15-3®

CA 125 II™CA 19-9™TPA®-MNSES100AFPhCG/ß-hCGhTgß2-MicroglobulinTKCalcitonin

TORCHToxo IgGToxo IgMToxo IgG AvidityRubella IgGRubella IgMCMV IgGCMV IgMCMV IgG AvidityHSV-1/2 IgGHSV-1 IgGHSV-2 IgGHSV-1/2 IgMParvovirus B19 IgGParvovirus B19 IgM

BORRELIABorrelia burgdorferi IgGBorrelia burgdorferi IgM

TREPONEMATreponema Screen

VZVVZV IgGVZV IgM

OTHER INFECTIOUS DISEASESMycoplasma pneumoniae

* Under development

The Family Collection

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A Wide Range of Specialty Tests

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Worldwide Corporate Headquarters

DiaSorin S.p.A.Via Crescentino - 13040 Saluggia (VC) - Italy

Tel. +39.0161.487526 - Fax: +39.0161.487670www.diasorin.com - E-mail: [email protected]