SAR Prostate DFP – Teaching Case of the Week 5/21/18 QUALITY … · 2019-04-02 · Rajan T....
Transcript of SAR Prostate DFP – Teaching Case of the Week 5/21/18 QUALITY … · 2019-04-02 · Rajan T....
QUALITYIMPROVEMENT:ISTHEBIOPSYPATHOLOGY
REFLECTIVEOFDISEASEGRADE?
RajanT.Gupta,M.D.
SitharthanSekar,B.S.
SARProstateDFP–TeachingCaseoftheWeek5/21/18
� 56yearoldM� PSA-4.4ng/mL� PSADensity-0.20ng/mL2
� NegaJvepriorTRUS-guidedbiopsy� PresentstoDukeformpMRIand
evaluaJonofpossibleprostatecancer
History
CasecourtesyofRajanT.Gupta,MD;DukeUniversityMedicalCenter
T2W ADC
b1400 CasecourtesyofRajanT.Gupta,MD;DukeUniversityMedicalCenter
� AxialT2W-lesioninrightanteriorPZatlevelofthemid-gland/apex� Lesionmeasured1.6cminmaximalaxialdimension
� CorrespondingareaofmarkedrestricJondiffusiononADCandb1400images
MRIInterpretaJon
CasecourtesyofRajanT.Gupta,MD;DukeUniversityMedicalCenter
� OverallPI-RADSCategory5� Thelesionwasupgradedfroma4to5,duetoitssizegreaterthan1.5cm.
MRIInterpretaJon
CasecourtesyofRajanT.Gupta,MD;DukeUniversityMedicalCenter
� TargetedMRI-USfusionbiopsyàG3+3=6PCa� MulJdisciplinaryteammettoreviewresults� Lowgradetumorfelttobediscordantwith
imagingfindings� PaJentunderwentradicalprostatectomydue
tohighsuspicionofclinicallysignificantcanceranddiscordancewithfusionbiopsy� FinalsurgicalpathologyrevealedG3+4=7PCa
FollowUp
CasecourtesyofRajanT.Gupta,MD;DukeUniversityMedicalCenter
� PI-RADS5lesionshaveveryhighlikelihoodofclinicallysignificantcancer
� Discordantbiopsyresultsrequirefollowup� Inthiscase,mulJdisciplinaryteamshould
(Radiology,Urology,andPathology)reviewpathologyanddetermineconcordance/discordanceandnextstepsinmanagement
TeachingPoints
CasecourtesyofRajanT.Gupta,MD;DukeUniversityMedicalCenter
THANKYOU
RajanT.Gupta,M.D.AssociateProfessorofRadiology
AssistantProfessorofSurgeryDirector,AbdominalImagingFellowshipProgram
DukeUniversityMedicalCenter&[email protected]
@RajanTGuptaMD
SARProstateDFP–TeachingCaseoftheWeek5/21/18