Medical Imaging• Il medical imaging è

attualmente in grado, con varie tecniche, di fornire informazioni su scala dal cm fino a m (cellula)

• Imaging multimodale (funzionale – anatomico, informazione integrata)

• Applicazioni: diagnostica, validazione protocolli terapeutici, studio di processi in-vivo

Approccio multidisciplinareClassico campo in cui c’e’ bisogno di competenze interdisciplinari sia all’interno del dipartimento che con gli altri dipartimenti. Infatti non esiste una sola tecnica elettiva ma molte tecniche possono essere usate, cosi come molti processi possono essere studiati e investigati in ambiti di vario genere. Es. appunto stem cell, diagnostica, sviluppo di nuovi farmaci, neuroscienze …

… Applying the new molecular imaging tools to humans will make a fundamental improvement in how cancer is understood in vivo and should allow earlier detection, stratification of patients for treatment, and objective evaluation of new therapies in a given patient.The outcome will be considerably better management and care of those with cancer.

• Screening/Prevenzione• Diagnosi precoce• Monitor di efficacia terapeutica /

medicina personalizzata• Diagnosi/terapia combinate

(“Theranostics”)• Image guidance” di terapia

rigenerativa• Controllo dell’efficacia terapeutica• Chirurgia e biopsia “Imagine-guided” • Follow-up

Molecular Libraries and Imaging

The Molecular Imaging Roadmap has three components:1.High-Specificity/High-Sensitivity Molecular Imaging Probes. The goal of this initiative is to improve probe detection sensitivity 10- to 100-fold within 5 years. 2.Molecular Imaging and Contrast Agent Database (MICAD). This new database catalogs imaging probe information, describing the specificities, activities, and applications of imaging probes for a wide range of diseases and biological functions. 3.Imaging Probe Development Center (IPDC). This center offers the production of known imaging probes for the research community in cases where there is no viable commercial supplier, and generates novel imaging probes for biomedical research and clinical applications.

Life Sciences Fund grants awards to launch health researchPublic release date: 17-Apr-2008

Patricia Kuhl, University of Washington, $4,033,304Program title: Early Learning and Brain Development: MEG Brain Imaging Center for Infants and Children Program focus: To establish a regional child brain imaging center to utilize the latest in brain imaging technology to measure the young brain in action and explore the basic mechanisms, and the potential underlying problems, that drive early learning and lay the foundation for life-long learning.Children's brain responses to events such as thinking, listening to language and music, and social interactions have been linked to their subsequent development and learning capacity. The investigators will use magneto-encephalography (MEG), a technology which is new to Washington State. MEG measures brain waves at the surface of the scalp in a non-invasive, noiseless process. This will be the only MEG in the world devoted to children. The behaviors, syndromes, and disabilities that will be addressed by the team represent unmet medical needs and are all prevalent in Washington State and worldwide. Improved understanding of the causes and possible treatment of autism, ADHD, dyslexia, learning difficulties and other diseases with early childhood onset will have profound implications for both the educational and health-care systems.

www.lsdfa.org/home.html

The Medical Imaging Conference (MIC) in collaboration with the Nuclear Science Symposium, is one of the outstanding scientific meetings where innovative research results on physical, technological and mathematical aspects of radiotracer-based medical imaging are presented. It provides a unique interdisciplinary platform for discussing future developments in medical imaging along the whole chain from basic research to medical application. Following the ongoing trend to multimodality and to the synergistic exchange of algorithms and methodology, MIC attracts researchers from the whole field of medical imaging. These technological developments result in a steady increase of the diagnostic power of medical imaging techniques and facilitate new therapeutic approaches.

• Founded: 29 December 2000

• The mission of the NIBIB is to improve human health by providing leadership for development and accelerating the application of biomedical technologies. The Institute is committed to integrating engineering and physical sciences with the life sciences to advance basic research and medical care.

NIBIB Intramural Labs

• Positron Emission Tomography (PET) Radiochemistry Group

• Laboratory of Bioengineering and Physical Science

– Drug Delivery and Kinetics – Instrumentation Research and

Development – Molecular Interactions – Nanoscale Immunodiagnostics – Protein Biophysics – Supramolecular Structure and Function

Scientific Program Areas (Extramural)

BiomaterialsBiomedical Informatics Drug and Gene Delivery Systems and Devices Image-Guided Interventions Image Processing, Visual Perception and Display Imaging Agents and Molecular Probes Magnetic, Biomagnetic and Bioelectric Devices Magnetic Resonance Imaging and Spectroscopy Mathematical Modeling, Simulation and Analysis Multi-Scale Modeling Initiative Medical Devices and Implant Science Micro-Biomechanics Micro- and Nano-Systems; Platform Technologies Nanotechnology Nuclear Medicine Optical Imaging and Spectroscopy Rehabilitation Engineering Sensors Structural Biology Surgical Tools, Techniques and Systems Telehealth Tissue Engineering Ultrasound: Diagnostic and Interventional X-ray, Electron, and Ion Beam

http://www.nibib.nih.gov/Research/ProgramAreas

http://www.nibib.nih.gov/Research/Intramural

Medical Imaging

Medical imaging

• Multidisciplinarietà, Multimodality Tecnologie e salute

• Diagnosi precoce, funzionale, specifica

• Molecular Imaging in-vivo

• Image-guidance di terapie, ad es. con cellule staminali