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Curriculum vitae
Professor, MD, DMSc Kjeld Søballe Aarhus University Hospital, Århus Sygehus, Department of Orthopaedic Surgery Tage-‐Hansens Gade 2, DK-‐8000 Århus C
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Personal data Name: Kjeld Søballe, Professor, MD, DMSc Employment: Aarhus University Hospital, Århus Sygehus, Department of Orthopaedic Surgery, Tage-‐Hansens Gade 2, DK-‐ 8000 Aarhus C Private address: Ordrupvej 18, 8000 Aarhus C. Telephone No.: 86 11 24 00 / 20 62 04 45 E-‐mail address: [email protected] Education 1994: Specialist in Orthopaedic surgery 1994: DMSc, University of Aarhus, Denmark 1983: MD, University of Aarhus, Denmark Scientific positions 2007: Head of graduate programme within clinical medicine, University of Aarhus 2005: Full clinical Professorship in Orthopaedic Surgery, Aarhus University Hospital 2003 Honorary professor, Department of Orthopaedic Surgery, University of Minnesota, USA 2001: Clinical professor in Orthopaedics, Aarhus University Hospital (5 years) 1998: Nominated number one for a full clinical professorship in Orthopaedics, University of CPH 1998: Associate professor, Danish Institute for Health Technology Assessment (DIHTA) 1998: Associate professor, University Hospital of Aarhus 1995: Assisting professor, University Hospital of Aarhus 1994: Research and clinical fellowship, Dept. of Orthopaedics, University of Minnesota, USA 1987: Research Fellowship in Orthopaedics, Aarhus University Hospital Bibliography Peer-‐reviewed papers: 253 Citations: 3742 H-‐index: 32 Invited lectures: 175 Book chapters: 11 Book chapters in teaching books: 2 (coeditor of Ortopædisk Kirurgi by Otto Sneppen) Current research interest Experimental basic research in implant fixation, ceramic coatings, bone grafting, growth factors, cytokines, wear debris, nano science, tissue engineering, therapeutic peptides, gene technology, stem cells, clinical studies of total joints, epidemiology of osteoarthrosis, clinical databases, fast-‐track programmes and health economic research. Member of evaluation of scientific theses DMSc theses: 5 theses PhD theses: 39 theses Diploma theses: 32 theses
Curriculum vitae
Professor, MD, DMSc Kjeld Søballe Aarhus University Hospital, Århus Sygehus, Department of Orthopaedic Surgery Tage-‐Hansens Gade 2, DK-‐8000 Århus C
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Awards Queen Ingrid's Reseach Prize 2009 (100,000 DKK) Best poster, Danish Orthopaedic Society, 2005, 2008, 2009 Award Paper, Danish Orthopaedic Society, 1995, 1997, 1998, 2000, 2001, 2002, 2004, 2007 Best Poster Award, PhD Day, Aarhus University, 2006, 2007, 2009 Kappa Delta Award, Orthopaedic Research Society 2005 William Harris Award, Washington DC, 2005 (5,000 USD) Award paper. Hip International, Baveno 2002 Acta Orthopaedica Scandinavica Award article year 2000, 2002 (2 x 10,000 USD) Young investigator award. Combined Orthopaedic Reseach Society Meeting, Hamamatsu, Japan, 1997 Young investigator award. Orthopaedic Research Society, Atlanta, 1997 European Society of Biomechanics (ESB) Research Award for 1996 European Society for Biomaterials award. Amsterdam, 1988
Memberships Treasurer of the European Hip Society Member of the Danish Orthopaedic Society Member of the European Orthopaedic Research Society Member of the Orthopaedic Research Society Member of the Research Council of the Danish Rheumatism Association Member of the Danish Steering Committee of “The Bone and Joint Decade 2000-‐2010” Member of the Danish Standards Association, representing Danish orthopaedic surgery Member of the Committee on Good Clinical Practice, University of Aarhus Member of the Danish Medico-‐legal Council Member of the Executive Committee, iNano Center, University of Aarhus 2002 Member of the Steering Committee, Ganganalyselaboratoriet, Hammel Member of the Steering Committee, Orthopaedic Joint Database Member of the Board of Directors, Peter Ryholt’s Trust Fund Member of the Board (chairman), Ortopædkirurgisk Forskningsfond i Århus og Thomasens Legat Aarhus Mountain Bike Club President of the Nordic Orthopaedic Federation’s Congress in Århus, 2010 Member of the Editorial Board, Acta Orthopaedica Scandinavica
Selection Committee Chief Physician, Frederiksberg Hospital, 2009 Associated professorship in orthopedic surgery, University of Aarhus, 2009 Professor in orthopaedics, University of Aarhus, 2007 Associated professorship, University of Aarhus, 2006 Professor in orthopaedics, University of Oslo, Norway, 2004 Professorship in sensory motor function, Aarhus University Hospital, 2004 Professorship in pathology, University of Aarhus, 2004 Associated professorship, University of Aarhus, 2003 Associated professorship, University of Aarhus, 2002
Curriculum vitae
Professor, MD, DMSc Kjeld Søballe Aarhus University Hospital, Århus Sygehus, Department of Orthopaedic Surgery Tage-‐Hansens Gade 2, DK-‐8000 Århus C
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Supervisor Experience DMSc theses: Completed 1. Martin Lind 1998 2. Søren Overgaard 2000 3. Steffen Jacobsen 2006 4. Michael Ulrich-‐Vinter 2007 Diploma projects (research year): Completed 1. Martin Lind 1991 2. Ejnar Larsen 1991 3. Ole Rahbek 1996 4. Thomas Bo Jensen 1998 5. Marianne Toft 2001 6. Thomas Andersen 2002 7. Carsten Stengaard 2003 8. Mette Koefoed 2004 9. Helle Dahl Pedersen 2004 10. Dea Mathiesen 2005 11. Thomas V. Jakobsen 2005 12. Helene Juhl 2005 13. Charlotte Eriksen 2005 14. Kirill Gromov 2005 15. Martin Skøtt 2005 16. Lilli Ørris Skov 2005 17. Kim Gerloev 2005 18. Stefan Stender 2006 19. Christian Rahbek 2006 20. Lars Mikael Stensman 2006 21. Gitte Refsgård 2006 22. Karen Toftdahl 2006 23. Sys Hasslund 2007 24. Lise Beier Ommen 2007 25. Sidsel Hastrup 2007 26. Kasra Zainali 2007 27. Mette Lind Cole 2007 28. Kirsten Jellesmark 2007 29. Marie Bak 2008 30. Kristian Behrndtz 2008 31. Rikke Vestergaard 2008 32. Mikkel Saksø Mortensen 2009 33. Henrik Saksø 2009 34. Andreas West in progress 35. Peter Uhrbrand in progress 36. Finn Sørensen in progress 37. Sigurd Beier Sloth in progress 38. Klas Gustafson in progress PhD projects: Completed 1. Martin Lind, ph.d. 1996 2. Ole Rahbek 2002 3. Michel Ulrich-‐Vinther 2002 4. Søren Kold 2003 5. Thomas Bo Jensen 2003 6. Brian Elmengaard 2004 7. Marianne Nygaard 2005 8. Mogens Berg Laursen 2005 9. Alma B. Pedersen 2006 10. Berit Zippor 2007 11. Mette Ørskov Sjøland 2007 12. Anders Lamberg 2007 13. Inger Mechlenburg 2007
14. Thomas Baad Hansen 2007 15. Mette Krintel Petersen 2008 16. Britta Hørdam 2008 17. Jørgen Baas 2008 18. Stig Jakobsen 2008 19. Kristian Larsen 2008 20. Thomas V. Jacobsen 2008 21. Anders Troelsen 2009 22. Maiken Stilling 2009 23. Thomas H.L. Jensen 2009 24. Kirill Gromov 2009 25. Theis Thillemann 2009 26. Ole Gade Sørensen 2010 27. Tine Steen Rubak 2010 28. Karen V. Andersen 2010 29. Jesper Schønnemann 2010 30. Juozas Petruskevicius 2010 31. Henrik Daugaard 2010 32. Marianne Toft Vestermark 2011 33. Mette Koefoed in progress 34. Kasra Zainali in progress 35. Marie Bagger Bohn in progress 36. Michael Kjeldager Tjørnild in progress 37. Nina Dyrberg Lorenzen in progress 38. Sys Hasslund in progress 39. Birgit Skoffer in progress 40. Mette Sørensen in progress 41. Samir Munir in progress 42. Rikke Vestergaard in progress 43. Jeppe Lange in progress 44. Martin Vesterby in progress 45. Michael Kjær Jakobsen in progress 46. Charlotte Hartig Andreasen in progress 47. Jeppe Barckman in progress 48. Lone Ramer Mikkelsen in progress 49. Anette Liljensøe in progress 50. Karen Toftdahl Bjørnholdt in progress 51. Mikkel Tøttrup in progress 52. Sepp de Raedt in progress
Curriculum vitae
____________________________________________________________________________________________ Professor, MD, DMSc Kjeld Søballe Aarhus University Hospital, Århus Sygehus, Department of Orthopaedic Surgery Tage-‐Hansens Gade 2, DK-‐8000 Århus C
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Foundation and grants
Funded by Year Grants
(number) Amount in DKK
The Danish Council for Independent Research | Medical Sciences
2002
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224.944
The Danish Council for Independent Research | Medical Sciences 2003 3 1.476.818 The Danish Council for Independent Research | Medical Sciences 2004 4 780.858 The Danish Council for Independent Research | Medical Sciences 2005 5 1.392.608 A.P. Møller Foundation 2005 1 10.218.000 The Lundbeck Foundation 2005 1 750.000 The Danish Rheumatism Association 2005 2 258.319 The Research Foundation Aarhus University 2005 1 110.832 The Danish Council for Independent Research | Medical Sciences 2006 2 420.888 Institute of Clinical Medicine 2006 1 120.000 The Danish Rheumatism Association 2006 4 420.000 Aase og Ejnar Danielsen Foundation 2006 1 100.000 Karen Elise Jensens Foundation 2007 1 1.000.000 The Danish Council for Independent Research | Medical Sciences 2007 3 2.124.000 The Danish Rheumatism Association 2007 2 407.856 Aase og Ejnar Danielsen Foundation 2007 2 200.000 Augustinus Foundation 2007 1 100.000 The Danish Rheumatism Association DORG 2008 1 484.000 The Danish Rheumatism Association 2008 4 951.500 The Lundbeck Foundation 2008 2 35.450.000 Sahva Foundation 2009 1 100.000 The Health Insurance Foundation 2009 1 300.000 The Danish Rheumatism Association 2009 1 100.000 The Danish Council for Technology and Innovation 2009 1 18.500.000 Furlong Research Charitable Foundation (UK) 2009 1 1.073.559 Institute of Clinical Medicine 2009 1 200.000 The Danish Council for Independent Research | Medical Sciences 2009 1 139.185 Institute of Clinical Medicine 2010 1 200.000 The Riisfort Foundation 2010 1 232.217 The Asker Larsen Founndation 2011 1 1.496.705 The Toyota Foundation
2011 1 100.000
Published items and Citations in each year from Web of Science
Curriculum vitae
____________________________________________________________________________________________ Professor, MD, DMSc Kjeld Søballe Aarhus University Hospital, Århus Sygehus, Department of Orthopaedic Surgery Tage-‐Hansens Gade 2, DK-‐8000 Århus C
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Original publications the last 5 years (2006 February – 2011 February)
2006
140. Swider P, Pedrono A, Mouzin O, Soballe K, Bechtold JE. Biomechanical analysis of the shear behaviour adjacent to an axially loaded implant. J Biomech 2006;39:1873-‐82.
141. Kold S, Rahbek O, Vestermark M, Overgaard S, Soballe K. Bone compaction enhances fixation of weight-‐bearing hydroxyapatite-‐coated implants. J Arthroplasty 2006;21:263-‐70.
142. Jakobsen T, Kold S, Bechtold JE, Elmengaard B, Soballe K. Effect of topical alendronate treatment on fixation of implants inserted with bone compaction. Clin Orthop Relat Res 2006;444:229-‐34.
143. Pedersen EN, Alkjaer T, Soballe K, Simonsen EB. Walking pattern in 9 women with hip dysplasia 18 months after periacetabular osteotomy. Acta Orthop 2006;77:203-‐8.
144. Laursen MB, Nielsen PT, Soballe K. Detection of bony defects around cementless acetabular components in total hip arthroplasty: a DEXA study on 10 human cadavers. Acta Orthop 2006;77:209-‐17.
145. Jacobsen S, Romer L, Soballe K. The other hip in unilateral hip dysplasia. Clin Orthop Relat Res 2006;446:239-‐46.
146. Toftdahl K, Nikolajsen L, Soballe K, Tonnesen E. [Postoperative analgesia following total knee arthroplasty]. Ugeskr Laeger 2006;168:1991-‐6.
147. Petersen MK, Soballe K. [Length of stay after total hip and knee arthroplasty]. Ugeskr Laeger 2006;168:2137.
148. Conroy MJ, Pedrono A, Bechtold JE, Soballe K, Ambard D, Swider P. High-‐resolution magnetic resonance flow imaging in a model of porous bone-‐implant interface. Magn Reson Imaging 2006;24:657-‐61.
149. Nygaard M, Elling F, Bastholm L, Soballe K, Borgwardt A. No difference in early cellular response of the pseudo-‐synovial membrane after total hip arthroplasty: comparison of 3 combinations of bearing materials. Acta Orthop 2006;77:402-‐12.
150. Skott M, Andreassen TT, Ulrich-‐Vinther M, Chen X, Keyler DE, LeSage MG, Pentel PR, Bechtold JE, Soballe K. Tobacco extract but not nicotine impairs the mechanical strength of fracture healing in rats. J Orthop Res 2006;24:1472-‐9.
151. Baad-‐Hansen T, Kold S, Fledelius W, Nielsen PT, Soballe K. Comparison of performance of conventional and minimally invasive surgery acetabular reamers. Clin Orthop Relat Res 2006;448:173-‐9.
152. Petersen MK, Madsen C, Andersen NT, Soballe K. Efficacy of multimodal optimization of mobilization and nutrition in patients undergoing hip replacement: a randomized clinical trial. Acta Anaesthesiol Scand 2006;50:712-‐7.
153. Johnsen SP, Sorensen HT, Lucht U, Soballe K, Overgaard S, Pedersen AB. Patient-‐related predictors of implant failure after primary total hip replacement in the initial, short-‐ and long-‐terms. A nationwide Danish follow-‐up study including 36,984 patients. J Bone Joint Surg Br 2006;88:1303-‐8.
154. Baas J, Lamberg A, Jensen TB, Elmengaard B, Soballe K. The bovine bone protein lyophilisate Colloss improves fixation of allografted implants-‐-‐an experimental study in dogs. Acta Orthop 2006;77:791-‐8.
155. Lamberg A, Schmidmaier G, Soballe K, Elmengaard B. Locally delivered TGF-‐beta1 and IGF-‐1 enhance the fixation of titanium implants: a study in dogs. Acta Orthop 2006;77:799-‐805.
Curriculum vitae
____________________________________________________________________________________________ Professor, MD, DMSc Kjeld Søballe Aarhus University Hospital, Århus Sygehus, Department of Orthopaedic Surgery Tage-‐Hansens Gade 2, DK-‐8000 Århus C
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2007
156. Nygaard M, Bastholm L, Elling F, Soballe K, Borgwardt A. Can ultrastructural particle location predict aseptic loosening? A biopsy study of nonloose hip implants one year postoperative using three bearing material combinations. J Long Term Eff Med Implants 2007;17:321-‐34.
157. Baad-‐Hansen T, Kold S, Fledelius W, Nielsen PT, Soballe K. Alteration of the hip joint centre during acetabular reaming. Hip International 2007;17:15-‐20.
158. Jensen TB, Overgaard S, Lind M, Rahbek O, Bunger C, Soballe K. Osteogenic protein-‐1 increases the fixation of implants grafted with morcellised bone allograft and ProOsteon bone substitute: an experimental study in dogs. J Bone Joint Surg Br 2007;89:121-‐6.
159. Swider P, Conroy M, Pedrono A, Ambard D, Mantell S, Soballe K, Bechtold JE. Use of high-‐resolution MRI for investigation of fluid flow and global permeability in a material with interconnected porosity. J Biomech 2007;40:2112-‐8.
160. Troelsen A, Soballe K. [Idiopathic osteoarthritis of the hip]. Ugeskr Laeger 2007;169:390.
161. Troelsen A, Romer L, Soballe K. [Hip dysplasia: clinical assessment, radiologic evaluation and reference]. Ugeskr Laeger 2007;169:394-‐6.
162. Petersen MK, Andersen KV, Andersen NT, Soballe K. "To whom do the results of this trial apply?" External validity of a randomized controlled trial involving 130 patients scheduled for primary total hip replacement. Acta Orthop 2007;78:12-‐8.
163. Mechlenburg I, Nyengaard JR, Gelineck J, Soballe K. Cartilage thickness in the hip joint measured by MRI and stereology-‐-‐a methodological study. Osteoarthritis Cartilage 2007;15:366-‐71.
164. Jakobsen T, Kold S, Bechtold JE, Elmengaard B, Soballe K. Local alendronate increases fixation of implants inserted with bone compaction: 12-‐week canine study. J Orthop Res 2007;25:432-‐41.
165. Laursen MB, Nielsen PT, Soballe K. Bone remodelling around HA-‐coated acetabular cups : a DEXA study with a 3-‐year follow-‐up in a randomised trial. Int Orthop 2007;31:199-‐204.
166. Toftdahl K, Nikolajsen L, Haraldsted V, Madsen F, Tonnesen EK, Soballe K. Comparison of peri-‐ and intraarticular analgesia with femoral nerve block after total knee arthroplasty: a randomized clinical trial. Acta Orthop 2007;78:172-‐9.
167. Andersen KV, Pfeiffer-‐Jensen M, Haraldsted V, Soballe K. Reduced hospital stay and narcotic consumption, and improved mobilization with local and intraarticular infiltration after hip arthroplasty: a randomized clinical trial of an intraarticular technique versus epidural infusion in 80 patients. Acta Orthop 2007;78:180-‐6.
168. Stender S, Murphy M, O'Brien T, Stengaard C, Ulrich-‐Vinther M, Soballe K, Barry F. Adeno-‐associated viral vector transduction of human mesenchymal stem cells. Eur Cell Mater 2007;13:93-‐9.
169. Jensen TB, Bechtold JE, Chen X, Soballe K. Systemic alendronate treatment improves fixation of press-‐fit implants: a canine study using nonloaded implants. J Orthop Res 2007;25:772-‐8.
170. Mechlenburg I, Kold S, Romer L, Soballe K. Safe fixation with two acetabular screws after Ganz periacetabular osteotomy. Acta Orthop 2007;78:344-‐9.
171. Baad-‐Hansen T, Kold S, Kaptein BL, Soballe K. High-‐precision measurements of cementless acetabular components using model-‐based RSA: an experimental study. Acta Orthop 2007;78:463-‐9.
Curriculum vitae
____________________________________________________________________________________________ Professor, MD, DMSc Kjeld Søballe Aarhus University Hospital, Århus Sygehus, Department of Orthopaedic Surgery Tage-‐Hansens Gade 2, DK-‐8000 Århus C
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172. Jakobsen SS, Larsen A, Stoltenberg M, Bruun JM, Soballe K. Effects of as-‐cast and wrought Cobalt-‐Chrome-‐Molybdenum and Titanium-‐Aluminium-‐Vanadium alloys on cytokine gene expression and protein secretion in J774A.1 macrophages. Eur Cell Mater 2007;14:45-‐54.
173. Jakobsen T, Baas J, Bechtold JE, Elmengaard B, Soballe K. Soaking morselized allograft in bisphosphonate can impair implant fixation. Clin Orthop Relat Res 2007;463:195-‐201.
174. Troelsen A, Jacobsen S, Bolvig L, Gelineck J, Romer L, Soballe K. Ultrasound versus magnetic resonance arthrography in acetabular labral tear diagnostics: a prospective comparison in 20 dysplastic hips. Acta Radiol 2007;48:1004-‐10.
175. Jorgensen PH, Gromov K, Soballe K. [Prevention of prosthesis infections]. Ugeskr Laeger 2007;169:4159-‐63.
176. Jakobsen SS, Danscher G, Stoltenberg M, Larsen A, Bruun JM, Mygind T, Kemp K, Soballe K. Cobalt-‐chromium-‐molybdenum alloy causes metal accumulation and metallothionein up-‐regulation in rat liver and kidney. Basic Clin Pharmacol Toxicol 2007;101:441-‐6.
177. Soballe K, Chen X, Jensen TB, Kidder L, Bechtold JE. Alendronate treatment in the revision setting, with and without controlled implant motion: an experimental study in dogs. Acta Orthop 2007;78:800-‐7.
2008
178. Li D, Gromov K, Soballe K et al. Quantitative mouse model of implant-‐associated osteomyelitis and the kinetics of microbial growth, osteolysis, and humoral immunity. J Orthop Res 2008;26:96-‐105.
179. Basile P, Dadali T, Jacobson J, Hasslund S, Ulrich-‐Vinther M, Soballe K, Nishio Y, Drissi MH, Langstein HN, Mitten DJ, O'Keefe RJ, Schwarz EM, Awad HA. Freeze-‐dried tendon allografts as tissue-‐engineering scaffolds for Gdf5 gene delivery. Mol Ther 2008;16:466-‐73.
180. Troelsen A, Elmengaard B, Soballe K. A new minimally invasive transsartorial approach for periacetabular osteotomy. J Bone Joint Surg Am 2008;90:493-‐8.
181. Troelsen A, Jacobsen S, Romer L, Soballe K. Weightbearing anteroposterior pelvic radiographs are recommended in DDH assessment. Clin Orthop Relat Res 2008;466:813-‐9.
182. Petersen MK, Andersen NT, Soballe K. Self-‐reported functional outcome after primary total hip replacement treated with two different periopera-‐tive regimes: a follow-‐up study involving 61 patients. Acta Orthop 2008;79:160-‐7.
183. Larsen K, Sorensen OG, Hansen TB, Thomsen PB, Soballe K. Accelerated perioperative care and rehabilitation intervention for hip and knee replacement is effective: a randomized clinical trial involving 87 patients with 3 months of follow-‐up. Acta Orthop 2008;79:149-‐59.
184. Larsen K, Hvass KE, Hansen TB, Thomsen PB, Soballe K. Effectiveness of accelerated perioperative care and rehabilitation intervention compared to current intervention after hip and knee arthroplasty. A before-‐after trial of 247 patients with a 3-‐month follow-‐up. BMC Musculoskelet Disord 2008;9:59.
185. Troelsen A, Elmengaard B, Romer L, Soballe K. Reliable angle assessment during periacetabular osteotomy with a novel device. Clin Orthop Relat Res 2008;466:1169-‐76.
186. Hasslund S, Jacobson JA, Dadali T, Basile P, Ulrich-‐Vinther M, Soballe K, Schwarz EM, O'Keefe RJ, Mitten DJ, Awad HA. Adhesions in a murine flexor tendon graft model: autograft versus allograft reconstruction. J Orthop Res 2008;26:824-‐33.
187. Thillemann TM, Pedersen AB, Johnsen SP, Soballe K. Inferior outcome after intraoperative femoral fracture in total hip arthroplasty: outcome in 519 patients from the Danish Hip Arthroplasty Registry. Acta Orthop 2008;79:327-‐34.
Curriculum vitae
____________________________________________________________________________________________ Professor, MD, DMSc Kjeld Søballe Aarhus University Hospital, Århus Sygehus, Department of Orthopaedic Surgery Tage-‐Hansens Gade 2, DK-‐8000 Århus C
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188. Baas J, Elmengaard B, Jensen TB, Jakobsen T, Andersen NT, Soballe K. The effect of pretreating morselized allograft bone with rhBMP-‐2 and/or pamidronate on the fixation of porous Ti and HA-‐coated implants. Biomaterials 2008;29:2915-‐22.
189. Larsen K, Hansen TB, Soballe K. Hip arthroplasty patients benefit from accelerated perioperative care and rehabilitation: a quasi-‐experimental study of 98 patients. Acta Orthop 2008;79:624-‐30.
190. Daugaard H, Elmengaard B, Bechtold JE, Soballe K. Bone growth enhancement in vivo on press-‐fit titanium alloy implants with acid etched microtexture. J Biomed Mater Res A 2008;87:434-‐40.
191. Mechlenburg I, Daugaard H, Soballe K. Radiation exposure to the orthopaedic surgeon during periacetabular osteotomy. International Orthopaedics 2008. Int Orthop. 2009;33:1747-‐51. [Epub 2008 Oct 29]
192. Thillemann TM, Pedersen AB, Johnsen SP, Soballe K. Implant survival after primary total hip arthroplasty due to childhood hip disorders: results from the Danish Hip Arthroplasty Registry. Acta Orthop 2008;79:769-‐76.
193. Troelsen A, Elmengaard B, Soballe K. Comparison of the minimally invasive and ilioinguinal approaches for periacetabular osteotomy: 263 single-‐surgeon procedures in well-‐defined study groups. Acta Orthop 2008;79:777-‐84.
194. Baas J, Elmengaard B, Bechtold J, Chen X, Soballe K. Ceramic bone graft substitute with equine bone protein extract is comparable to allograft in terms of implant fixation: a study in dogs. Acta Orthop 2008;79:841-‐50.
2009
195. Zainali K, Danscher G, Jakobsen T, Jakobsen SS, Baas J, Moller P, Bechtold JE, Soballe K. Effects of gold coating on experimental implant fixation. J Biomed Mater Res A 2009;88:274-‐80.
196. Jakobsen SS, Larsen A, Stoltenberg M, Bruun JM, Soballe K. Hydroxyapatite Coatings Did not Increase TGF-‐beta and BMP-‐2 Secretion in Murine J774A.1 Macrophages, but Induced a Pro-‐inflammatory Cytokine Response. J Biomater Sci Polym Ed 2009;20:455-‐65.
197. Elmengaard B, Bechtold JE, Chen X, Soballe K. Fixation of hydroxyapatite-‐coated revision implants is improved by the surgical technique of cracking the sclerotic bone rim. J Orthop Res 2009;27:996-‐1001.
198. Crane DP, Gromov K, Li D, Soballe K, Wahnes C, Buchner H, Hilton MJ, O'Keefe RJ, Murray CK, Schwarz EM. Efficacy of colistin-‐impregnated beads to prevent multidrug-‐resistant A. baumannii implant-‐associated osteomyelitis. J Orthop Res 2009;27:1008-‐15
199. Jakobsen T, Baas J, Kold S, Bechtold JE, Elmengaard B, Soballe K. Local bisphosphonate treatment increases fixation of hydroxyapatite-‐coated implants inserted with bone compaction. J Orthop Res 2009;27:189-‐94.
200. Troelsen A, Moller JK, Bolvig L, Pryno T, Pedersen LN, Soballe K. Animal-‐Associated Bacteria, Erysipelotrix rhusiopathiae, as the Cause of Infection in a Total Hip Arthroplasty Eradication by Standard Treatment Procedures. J Arthroplasty 2010;25:497.e21-‐3. [Epub 2009 Feb 4]
201. Baas J, Elmengaard B, Jakobsen T, Bechtold J, Soballe K. Crack Revision Improves Fixation of Uncemented HA coated Implants Compared with Reaming: An Experiment in Dogs. Clin Orthop Relat Res 2009;467:2638-‐43.
202. Daugaard H, Elmengaard B, Bechtold JE, Jensen T, Soballe K. The effect on bone growth enhancement of implant coatings with hydroxyapatite and collagen deposited electrochemically and by plasma spray. J Biomed Mater Res A 2010;92:913-‐21.
203. Stilling M, Nielsen KA, Soballe K, Rahbek O. Clinical Comparison of Polyethylene Wear with Zirconia or Cobalt-‐Chromium Femoral Heads. Clin Orthop Relat Res 2009;467:2644-‐50.
Curriculum vitae
____________________________________________________________________________________________ Professor, MD, DMSc Kjeld Søballe Aarhus University Hospital, Århus Sygehus, Department of Orthopaedic Surgery Tage-‐Hansens Gade 2, DK-‐8000 Århus C
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204. Stilling M, Rahbek O, Soballe K. Inferior Survival of Hydroxyapatite versus Titanium-‐coated Cups at 15 Years. Clin Orthop Relat Res 2009;467:2872-‐9.
205. Troelsen A, Soballe K. [Periacetabular osteotomy and hip dysplasia in young adults]. Ugeskr Laeger 2009;171:1185-‐9.
206. Larsen K, Hansen TB, Thomsen PB, Christiansen T, Soballe K. Cost-‐effectiveness of accelerated perioperative care and rehabilitation after total hip and knee arthroplasty. J Bone Joint Surg Am 2009;91:761-‐72.
207. Thillemann TM, Pedersen AB, Mehnert F, Johnsen SP, Soballe K. Use of diuretics and risk of implant failure after primary total hip arthroplasty: A nationwide population-‐based study. Bone 2009;45:499-‐504.
208. Troelsen A, Mechlenburg I, Gelineck J, Bolvig L, Jacobsen S, Soballe K. What is the role of clinical tests and ultrasound in acetabular labral tear diagnostics? Acta Orthop 2009; 80:314-‐8.
209. Hordam B, Sabroe S, Pedersen PU, Mejdahl S, Soballe K. Nursing intervention by telephone interviews of patients aged over 65 years after total hip replacement improves health status: a randomised clinical trial. Scand J Caring Sci 2010;24:94-‐100. [Epub 2009 Apr 28]
210. Thorup B, Mechlenburg I, Soballe K. Total hip replacement in the congenitally dislocated hip using the Paavilainen technique. Acta Orthop 2009; 80:259-‐62.
211. Swider P, Guerin G, Baas J, Soballe K, Bechtold JE. Characterization of bone-‐implant fixation using modal
analysis: Application to a press-‐fit implant model. J Biomech 2009;42:1643-‐9.
212. Pilgaard L, Lund P, Duroux M, Fink T, Ulrich-‐Vinther M, Soballe K, Zachar V. Effect of oxygen concentration, culture format and donor variability on in vitro chondrogenesis of human adipose tissue-‐derived stem cells. Regen Med 2009;4:539-‐48.
213. Lamberg A, Bechtold JE, Baas J, Soballe K, Elmengaard B. Effect of local TGF-‐beta1 and IGF-‐1 release on implant fixation: comparison with hydroxyapatite coating: a paired study in dogs. Acta Orthop 2009;80:499-‐504.
214. Troelsen A, Elmengaard B, Soballe K. Medium-‐term outcome of periacetabular osteotomy and predictors of conversion to total hip replacement. J Bone Joint Surg Am 2009;91:2169-‐79.
215. Jakobsen T, Baas J, Bechtold JE, Elmengaard B, Soballe K. The Effect of Soaking Allograft in Bisphosphonate: A Pilot Dose-‐response Study. Clin Orthop Relat Res 2010;468:867-‐74. [Epub 2009 Sep 18]
216. Hordam B, Soballe K, Pedersen PU. Differences in health status of older people aged 65 and above after total hip replacement compared with the normal population: a cross-‐sectional study. Int J Older People Nurs 2009;4:211-‐7.
217. Jensen T, Dolatshahi-‐Pirouz A, Foss M, Baas J, Lovmand J, Duch M, Pedersen FS, Kassem M, Bunger C, Soballe K, Besenbacher F. Interaction of human mesenchymal stem cells with osteopontin coated hydroxyapatite surfaces. Colloids Surf B Biointerfaces 2009.
218. Sorensen OG, Jakobsen BW, Kold S, Hansen TB, Soballe K. Serial dilation versus extraction drilling in anterior cruciate ligament reconstruction: a biomechanical study. Knee Surg Sports Traumatol Arthrosc 2010;18:742-‐6. [Epub 2009 Sep 26]
219. Husted H, Andersen KV, Soballe K. [Sick-‐leave and recovalescence following total knee and hip arthroplasty. Ugeskr Laeger 2009;171:2892-‐6.
220. Foldager CB, Munir S, Ulrich-‐Vinther M, Soballe K, Bunger C, Lind M. Validation of suitable house keeping genes for hypoxia-‐cultured human chondrocytes. BMC Mol Biol 2009;10:94.
Curriculum vitae
____________________________________________________________________________________________ Professor, MD, DMSc Kjeld Søballe Aarhus University Hospital, Århus Sygehus, Department of Orthopaedic Surgery Tage-‐Hansens Gade 2, DK-‐8000 Århus C
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221. Jensen TB, Bechtold JE, Chen X, Vestermark M, Soballe K. No effect of autologous growth factors (AGF) around ungrafted loaded implants in dogs. Int Orthop. 2010;34:925-‐30. [Epub 2009 Oct 25]
222. Thyssen JP, Jakobsen SS, Engkilde K, Johansen JD, Soballe K, Menne T. The association between metal allergy, total hip arthroplasty, and revision. Acta Orthop 2009;80:646-‐52.
223. Stilling M, Soballe K, Andersen NT, Larsen K, Rahbek O. Analysis of polyethylene wear in plain radiographs. Acta Orthop 2009;80:675-‐82.
2010
224. Thillemann TM, Pedersen AB, Mehnert F, Johnsen SP, Soballe K. Postoperative use of bisphosphonates and risk of revision after primary total hip arthroplasty: A nationwide population-‐based study. Bone 2010;46:946-‐51.
225. Jakobsen SS, Baas J, Jakobsen T, Soballe K. Biomechanical implant fixation of CoCrMo coating inferior to titanium coating in a canine implant model. J Biomed Mater Res A 2010;94:180-‐6.
226. Troelsen A, Romer L, Kring S, Elmengaard B, Soballe K. Assessment of hip dysplasia and osteoarthritis:
Variability of different methods. Acta Radiol 2010;51:187-‐93. 227. Mechlenburg I, Kold S, Soballe K. No change detected by DEXA in bone mineral density after periacetabular
osteotomy. Acta Orthop Belg 2009;75:761-‐6. 228. Baad-‐Hansen T, Storgaard JS, Soballe K. Two-‐year migration results of the ReCap hip resurfacing system-‐a
radiostereometric follow-‐up study of 23 hips. Int Orthop 2010. [Epub ahead of print]
229. Mechlenburg I, Nyengaard JR, Gelineck J, Soballe K, Troelsen A. Cartilage Thickness in the Hip Measured by MRI and Stereology Before and After Periacetabular Osteotomy. Clin Orthop Relat Res 2010;468:1884-‐90.
230. Li D, Gromov K, Proulx ST et al. Effects of antiresorptive agents on osteomyelitis: novel insights into the pathogenesis of osteonecrosis of the jaw. Ann N Y Acad Sci 2010;1192:84-‐94.
231. Thillemann TM, Pedersen AB, Mehnert F, Johnsen SP, Soballe K. The risk of revision after primary total hip arthroplasty among statin users: a nationwide population-‐based nested case-‐control study. J Bone Joint Surg Am 2010;92:1063-‐72.
232. Kehlet H, Soballe K. Fast-‐track hip and knee replacement -‐ what are the issues? Acta Orthop 2010.
233. Petersen MK, Andersen NT, Mogensen P, Voight M, Soballe K. Gait analysis after total hip replacement with hip resurfacing implant or Mallory-‐head Exeter prosthesis: a randomised controlled trial. Int Orthop 2010. [Epub ahead of print]
234. Jakobsen SS, Baas J, Jakobsen T, Soballe K. Acid etching does not improve CoCrMo implant osseointegration
in a canine implant model. Hip Int 2010;20:171-‐8.
235. Jensen J, Foldager CB, Jakobsen TV, Soballe K, Bunger C, Baas J. Use of carboxymethyl cellulose and collagen carrier with equine bone lyophilisate suggests late onset bone regenerative effect in a humerus drill defect -‐ a pilot study in six sheep. Open Orthop J 2010;4:181-‐7.
236. Husted H, Solgaard S, Hansen TB, Soballe K, Kehlet H. Care principles at four fast-‐track arthroplasty departments in Denmark. Dan Med Bull 2010;57:A4166.
237. Sorensen OG, Larsen K, Jakobsen BW, Kold S, Hansen TB, Taudal S, Lund B, Christiansen SE, Lind M, Soballe K.
Serial dilation reduces graft slippage compared to extraction drilling in anterior cruciate ligament
Curriculum vitae
____________________________________________________________________________________________ Professor, MD, DMSc Kjeld Søballe Aarhus University Hospital, Århus Sygehus, Department of Orthopaedic Surgery Tage-‐Hansens Gade 2, DK-‐8000 Århus C
11
reconstruction: a randomized controlled trial using radiostereometric analysis. Knee Surg Sports Traumatol Arthrosc 2010. [Epub ahead of print]
238. Sorensen OG, Larsen K, Jakobsen BW, Kold S, Hansen TB, Lind M, Soballe K. The combination of radiostereometric analysis and the telos stress device results in poor precision for knee laxity measurements after anterior cruciate ligament reconstruction. Knee Surg Sports Traumatol Arthrosc 2010. [Epub ahead of print]
239. Jensen T, Jakobsen T, Baas J, Nygaard JV, Dolatshahi-‐Pirouz A, Hovgaard MB, Foss M, Bunger C, Besenbacher
F, Soballe K. Hydroxyapatite nanoparticles in poly-‐D,L-‐lactic acid coatings on porous titanium implants conducts bone formation. J Biomed Mater Res A 2010. [Epub ahead of print]
240. Troelsen A, Romer L, Jacobsen S, Ladelund S, Soballe K. Cranial acetabular retroversion is common in
developmental dysplasia of the hip as assessed by the weight bearing position. Acta Orthop 2010;81:436-‐41.
241. Stilling M, Soballe K, Larsen K, Andersen NT, Rahbek O. Knee flexion influences periprosthetic BMD measurement in the tibia. Acta Orthop 2010;81:463-‐70.
242. Eriksen CG, Olsen H, Husted LB, Sorensen L, Carstens M, Soballe K, Langdahl BL. The Expression of IL-‐6 by Osteoblasts Is Increased in Healthy Elderly Individuals: Stimulated Proliferation and Differentiation Are Unaffected by Age. Calcif Tissue Int 2010. [Epub ahead of print]
243. Zainali K, Baas J, Jakobsen TV, Danscher G, Soballe K. Particulate gold as an anti-‐inflammatory mediator in bone allograft-‐An animal study. J Biomed Mater Res A 2010. [Epub ahead of print]
244. Stilling M, Larsen K, Andersen NT, Soballe K, Kold S, Rahbek O. The final follow-‐up plain radiograph is
sufficient for clinical evaluation of polyethylene wear in total hip arthroplasty. Acta Orthop 2010. [Epub ahead of print]
245. Andersen KV, Bak M, Christensen BV, Harazuk J, Pedersen NA, Soballe K. A randomized, controlled trial comparing local infiltration analgesia with epidural infusion for total knee arthroplasty. Acta Orthop 2010. [Epub ahead of print]
246. Orskov M, Abdulghani S, McCarthy I, Soballe K, Flivik G. Comparison of flanged and unflanged acetabular cup design. Acta Orthop 2010. [Epub ahead of print]
247. Swider P, Ambard D, Guerin G, Soballe K, Bechtold JE. Sensitivity analysis of periprosthetic healing to cell
migration, growth factor and post-‐operative gap using a mechanobiological model. Comput Methods Biomech Biomed Engin 2010;1. [Epub ahead of print]
248. Vestergaard RF, Jensen H, Vind-‐Kezunovic S, Jakobsen T, Soballe K, Hasenkam JM. Bone healing after median sternotomy: A comparison of two hemostatic devices. J Cardiothorac Surg 2010;5:117. [Epub ahead of print]
249. Larsen K, Hansen TB, Soballe K, Kehlet H. Patient-‐reported outcome after fast-‐track hip arthroplasty -‐ A prospective cohort study. Health Qual Life Outcomes 2010;8:144. [Epub ahead of print]
2011
250. Fink T, Rasmussen JG, Lund P, Pilgaard L, Soballe K, Zachar V. Isolation and expansion of adipose-‐derived stem
cells for tissue engineering. Front Biosci (Elite Ed) 2011;3:256-‐63.
251. Daugaard H, Elmengaard B, Andreassen TT, Baas J, Bechtold JE, Soballe K. The combined effect of parathyroid hormone and bone graft on implant fixation. J Bone Joint Surg Br 2011;93:131-‐9.
Curriculum vitae
____________________________________________________________________________________________ Professor, MD, DMSc Kjeld Søballe Aarhus University Hospital, Århus Sygehus, Department of Orthopaedic Surgery Tage-‐Hansens Gade 2, DK-‐8000 Århus C
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252. Lund B, Soballe K, Winge S, Holmich P, Jacobsen S, Lind M. [Hip arthroscopy.]. Ugeskr Laeger 2011;173:197-‐200.
253. Daugaard H, Elmengaard B, Andreassen T, Bechtold J, Lamberg A, Soballe K. Parathyroid Hormone Treatment Increases Fixation of Orthopedic Implants with Gap Healing: A Biomechanical and Histomorphometric Canine Study of Porous Coated Titanium Alloy Implants in Cancellous Bone. Calcif Tissue Int 2011.