Omeprazole/trimetazidine
Transcript of Omeprazole/trimetazidine
Reactions 1456 - 15 Jun 2013
SOmeprazole/trimetazidine
Constipation causing valsalva retinopathy: casereport
A 58-year-old man developed valsalva retinopathy as aresult of constipation, while receiving omeprazole andtrimeazidine.
The man started receiving omeprazole and trimetazidine[dosage and routes not stated] for chest pain. He presentedwith a 2-day history of central vision loss in his right eye.Fundal examination of his right eye showed a small area ofhaemorrhage over the supernasal aspect of the macula. Healso reported a 2-week history of constipation that had startedafter initiating trimetazidine and omeprazole [duration oftherapy to onset of reaction not stated]. He was diagnosed withvalsalva retinopathy; thought to have been caused by strainingduring bowel motions.
The man was managed conservatively. His premacularhaemorrhage resolved spontaneously 3 months after hispresentation and his visual symptoms subsided. Hismedication was adjusted and his constipation resolved.
Author comment: "We report a case of a gentleman whopresented with a 2-day history of sudden loss of right eyecentral vision and central scotoma. The diagnosis in this casewas valsalva retinopathy as a result of constipation, whichwas a side effect caused by medications (trimetazidine andomeprazole) for his chest pain."Chan JCW, et al. Can constipation lead to visual loss?. Hong Kong Practitioner 35:24-26, No. 1, Mar 2013 - Hong Kong 803088278
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Reactions 15 Jun 2013 No. 14560114-9954/10/1456-0001/$14.95 Adis © 2010 Springer International Publishing AG. All rights reserved